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The map label for this gene is rbsK [H]

Identifier: 222525125

GI number: 222525125

Start: 2357080

End: 2357991

Strand: Direct

Name: rbsK [H]

Synonym: Chy400_1863

Alternate gene names: 222525125

Gene position: 2357080-2357991 (Clockwise)

Preceding gene: 222525124

Following gene: 222525126

Centisome position: 44.74

GC content: 59.21

Gene sequence:

>912_bases
ATGACTCCTACGATTGTGGTTGTCGGTAGCCTGAACATGGATCTGGTAGTGCGCGCACCACGCCATCCACAACCGGGAGA
GACGGTTATTGGTAGTGATTTTCAAACCTTTCCGGGTGGTAAAGGGGCAAATCAGGCGGTGGCCGCAGCCCGGTTGGGAG
CACGTGTTCACCTTGTCGGGCGGGTGGGAGTAGATGCGTTCGGTCATACCCTGCTGGCGACAGCCCAAGAGCACGGCGTC
GATACCACCTTTGTCCAGCGTGACCCGACGGCACCTACCGGTGTTGCGCTGATTACCATTGACTCTCACGGTCAAAATAC
GATAGTTGTCGCGCCGGGTGCGAATATGCAGGTAACGGAAGCGGATGTGCTACGTGCAGAGTCGGTGCTGGCCACGGCTG
ATATGCTGTTGATGCAACTTGAATGTCCGCTTGAGGTCGTGATTGCGGCGGCCCGCCTGGCTCATCATCACGGTGTTCCG
GTGGTGTTAAATCCGGCCCCGGCCCGTCCGTTACCGGTTGATCTGTTGGCGCTGGTTGATTTCCTCATTCCCAATCAGCT
TGAATTGCAAGCCCTTGCCGAAGGTGAAGCCGATCTGCGCACCGCAATTCGCTATCTGCAACAACGTGGTGCTCGCAATG
TGGTGGTTACCCTGGCTGAAGCCGGCGCGGTCCTGGCCGAAGCCGATCAGATCATCCACGAGCCGGCGTTCGAGGTACCG
GTTGTCGATACGGTGGCGGCGGGTGATGCGTTTGTTGCTGCTTTCTGCGTTGCCAGCGCCAGCGGCAAATCGCCGCAGGA
GGCTGTACGTTGGGGAAACGCAGCCGGTGCGCTGGCAGTCACCCGTGAAGGTGCGCAGCCGTCATTGCCGGCCTATCGAG
AGGTGCTGCGGTTGTTGAAGGTTAGTGGGTGA

Upstream 100 bases:

>100_bases
AAACCGAATTGTTTGCCGGTCCCGCCATTACCATTCCCGGCAACATTTGCTATGATGTTGACCTGAGCCTTCGTTGATGA
ACGTCTGAGGGAGCACATCT

Downstream 100 bases:

>100_bases
GGGAATTTGCCCGGCATAACCCAAGTTGCCACCTTTATCACCACAGAGACACGAAGGACACCGAGGATGTGGATAACCGG
GGTTGCTCCCGTGAGGTGTG

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MTPTIVVVGSLNMDLVVRAPRHPQPGETVIGSDFQTFPGGKGANQAVAAARLGARVHLVGRVGVDAFGHTLLATAQEHGV
DTTFVQRDPTAPTGVALITIDSHGQNTIVVAPGANMQVTEADVLRAESVLATADMLLMQLECPLEVVIAAARLAHHHGVP
VVLNPAPARPLPVDLLALVDFLIPNQLELQALAEGEADLRTAIRYLQQRGARNVVVTLAEAGAVLAEADQIIHEPAFEVP
VVDTVAAGDAFVAAFCVASASGKSPQEAVRWGNAAGALAVTREGAQPSLPAYREVLRLLKVSG

Sequences:

>Translated_303_residues
MTPTIVVVGSLNMDLVVRAPRHPQPGETVIGSDFQTFPGGKGANQAVAAARLGARVHLVGRVGVDAFGHTLLATAQEHGV
DTTFVQRDPTAPTGVALITIDSHGQNTIVVAPGANMQVTEADVLRAESVLATADMLLMQLECPLEVVIAAARLAHHHGVP
VVLNPAPARPLPVDLLALVDFLIPNQLELQALAEGEADLRTAIRYLQQRGARNVVVTLAEAGAVLAEADQIIHEPAFEVP
VVDTVAAGDAFVAAFCVASASGKSPQEAVRWGNAAGALAVTREGAQPSLPAYREVLRLLKVSG
>Mature_302_residues
TPTIVVVGSLNMDLVVRAPRHPQPGETVIGSDFQTFPGGKGANQAVAAARLGARVHLVGRVGVDAFGHTLLATAQEHGVD
TTFVQRDPTAPTGVALITIDSHGQNTIVVAPGANMQVTEADVLRAESVLATADMLLMQLECPLEVVIAAARLAHHHGVPV
VLNPAPARPLPVDLLALVDFLIPNQLELQALAEGEADLRTAIRYLQQRGARNVVVTLAEAGAVLAEADQIIHEPAFEVPV
VDTVAAGDAFVAAFCVASASGKSPQEAVRWGNAAGALAVTREGAQPSLPAYREVLRLLKVSG

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=35.8108108108108, Blast_Score=154, Evalue=1e-37,
Organism=Escherichia coli, GI1790193, Length=303, Percent_Identity=42.5742574257426, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI87082343, Length=300, Percent_Identity=30.6666666666667, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788491, Length=293, Percent_Identity=24.2320819112628, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788484, Length=310, Percent_Identity=27.0967741935484, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=298, Percent_Identity=36.241610738255, Blast_Score=164, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6319884, Length=330, Percent_Identity=30.9090909090909, Blast_Score=132, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24583886, Length=298, Percent_Identity=35.5704697986577, Blast_Score=153, Evalue=1e-37,
Organism=Drosophila melanogaster, GI20128807, Length=301, Percent_Identity=36.2126245847176, Blast_Score=141, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31544; Mature: 31412

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTIVVVGSLNMDLVVRAPRHPQPGETVIGSDFQTFPGGKGANQAVAAARLGARVHLVG
CCCEEEEEECCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHCCEEEEEE
RVGVDAFGHTLLATAQEHGVDTTFVQRDPTAPTGVALITIDSHGQNTIVVAPGANMQVTE
ECCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCCEEECH
ADVLRAESVLATADMLLMQLECPLEVVIAAARLAHHHGVPVVLNPAPARPLPVDLLALVD
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHH
FLIPNQLELQALAEGEADLRTAIRYLQQRGARNVVVTLAEAGAVLAEADQIIHEPAFEVP
HHCCCCCEEHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCC
VVDTVAAGDAFVAAFCVASASGKSPQEAVRWGNAAGALAVTREGAQPSLPAYREVLRLLK
CCCEECCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
VSG
CCC
>Mature Secondary Structure 
TPTIVVVGSLNMDLVVRAPRHPQPGETVIGSDFQTFPGGKGANQAVAAARLGARVHLVG
CCEEEEEECCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHCCEEEEEE
RVGVDAFGHTLLATAQEHGVDTTFVQRDPTAPTGVALITIDSHGQNTIVVAPGANMQVTE
ECCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCCEEECH
ADVLRAESVLATADMLLMQLECPLEVVIAAARLAHHHGVPVVLNPAPARPLPVDLLALVD
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHH
FLIPNQLELQALAEGEADLRTAIRYLQQRGARNVVVTLAEAGAVLAEADQIIHEPAFEVP
HHCCCCCEEHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCC
VVDTVAAGDAFVAAFCVASASGKSPQEAVRWGNAAGALAVTREGAQPSLPAYREVLRLLK
CCCEECCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
VSG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]