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The map label for this gene is fur [H]

Identifier: 222525119

GI number: 222525119

Start: 2348194

End: 2348664

Strand: Direct

Name: fur [H]

Synonym: Chy400_1857

Alternate gene names: 222525119

Gene position: 2348194-2348664 (Clockwise)

Preceding gene: 222525118

Following gene: 222525124

Centisome position: 44.57

GC content: 55.63

Gene sequence:

>471_bases
ATGACCACAAATGCTTCCTCATCACCCCAACCGTCGCTTGATACACAGGCCTGGCTCAATAGTGTTCGGGCAGCATGGCA
GCGTACCGGTTTGCGCATTACGCTTCCTCGCATGCGGGTGATTGAAACGATTGCGTCATACCGTGCTCCTTTCAGTGCCG
AACAGCTTTACGCCGATCTGTGTACGCACAGTGAAACTCCTGGCCGGGCAACTGTTTATCGCACCATTGAACAACTTCAC
GCCAGTGGCTGGTTGGCCCGTATTCATGGGCCGGTCGGCGAAGAGGGGTATGTACCTTGCCATCCTGGTCATCTTCACCA
CCTGGTCTGTACCAGGTGCGGTGCGGTCACCAGCTTTGAAGGGTGCGATCTCGATAATTTGCTGAATCGGGTTGCGGCTG
AAACTGGCTTTAGCGTGGAGGGGCATCTCTTGCAGCTCTTTGGCCGTTGTGCGCGCTGTCAGGCCAATTGA

Upstream 100 bases:

>100_bases
TTGGGGCGGCCCTTGTGGCCGCCCTATGTCCATCGTATACGCGCTAACAACAGTGGTGCGACGCACTTGCTGAGAGCGTT
GCACCTGGATGCAAAGCACT

Downstream 100 bases:

>100_bases
TACAAGCTTATCGAAGTAACTGTGTAGAGGAAGAAACGGCGAAGGTAGTGCTTTTGCCGTTTCTTTGTTTGGGGGTTGAA
CAGGAACTAAGGACACCCTC

Product: Fur family ferric uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MTTNASSSPQPSLDTQAWLNSVRAAWQRTGLRITLPRMRVIETIASYRAPFSAEQLYADLCTHSETPGRATVYRTIEQLH
ASGWLARIHGPVGEEGYVPCHPGHLHHLVCTRCGAVTSFEGCDLDNLLNRVAAETGFSVEGHLLQLFGRCARCQAN

Sequences:

>Translated_156_residues
MTTNASSSPQPSLDTQAWLNSVRAAWQRTGLRITLPRMRVIETIASYRAPFSAEQLYADLCTHSETPGRATVYRTIEQLH
ASGWLARIHGPVGEEGYVPCHPGHLHHLVCTRCGAVTSFEGCDLDNLLNRVAAETGFSVEGHLLQLFGRCARCQAN
>Mature_155_residues
TTNASSSPQPSLDTQAWLNSVRAAWQRTGLRITLPRMRVIETIASYRAPFSAEQLYADLCTHSETPGRATVYRTIEQLHA
SGWLARIHGPVGEEGYVPCHPGHLHHLVCTRCGAVTSFEGCDLDNLLNRVAAETGFSVEGHLLQLFGRCARCQAN

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates the expression of the fbp protein [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=128, Percent_Identity=32.8125, Blast_Score=77, Evalue=4e-16,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17160; Mature: 17028

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNASSSPQPSLDTQAWLNSVRAAWQRTGLRITLPRMRVIETIASYRAPFSAEQLYADL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHCCCCCHHHHHHHH
CTHSETPGRATVYRTIEQLHASGWLARIHGPVGEEGYVPCHPGHLHHLVCTRCGAVTSFE
HHCCCCCCHHHHHHHHHHHHHHCCHHEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
GCDLDNLLNRVAAETGFSVEGHLLQLFGRCARCQAN
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTNASSSPQPSLDTQAWLNSVRAAWQRTGLRITLPRMRVIETIASYRAPFSAEQLYADL
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHCCCCCHHHHHHHH
CTHSETPGRATVYRTIEQLHASGWLARIHGPVGEEGYVPCHPGHLHHLVCTRCGAVTSFE
HHCCCCCCHHHHHHHHHHHHHHCCHHEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
GCDLDNLLNRVAAETGFSVEGHLLQLFGRCARCQAN
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8406856 [H]