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The map label for this gene is cefD [H]

Identifier: 222525063

GI number: 222525063

Start: 2277958

End: 2279163

Strand: Reverse

Name: cefD [H]

Synonym: Chy400_1800

Alternate gene names: 222525063

Gene position: 2279163-2277958 (Counterclockwise)

Preceding gene: 222525066

Following gene: 222525062

Centisome position: 43.26

GC content: 57.79

Gene sequence:

>1206_bases
ATGACAGCGACAACCTGCTCTCTGCCCATACCAGAACTGGCCGAACAATTTCTGCTCCGCCGCGATATGACCTTTCTCAA
CCACGGCAGCTTCGGTGCCTGTCCACAGCCGGTCTTTGCCGTCTATCAGCAGTGGCAGCGCACGCTTGAAGCACAACCGG
TTGAGTTTCTCGGACGACGTTTATCAGATTTGCTGTATCGCGCTCGTTCTGAACTGGCAGCTTTCGTCGGTGCAGCAGCA
GAGGATGTAGTCTTTGTCCCAAACGTCACCTACGCGCTCAACATTGTGGCCCGTTCGCTGGATTTGCAACCAGGCGATGA
AGTTTTGGGGATCACGCACGAGTACGGCGCTATCGAGCGTACCTGGCGCTACGTGTGTCTGCAACGAGGCGCAACTTACA
GGAACCAGCCGGTTGAACTGCCGGTAACGACGTCTGATGAGATCATCGATCAGATCTGGCAGGGAGTCACTCCGCGCACA
CGGGTTATGTTGATCAGCCATATCACCTCGCCAACGGCAATCGTGATGCCGGTGGCAGAGGTATGCCGGCGGGCACGGGC
AGCAGGGATTCTCACCGTGATAGACGGTGCGCATGCGCCGGGTCAGATCGACCTGAATCTGCACGAGTTAGCCCCCGATT
TCTACGCCGGTAACTGTCACAAATGGTTGTGCGCCCCCAAAGGGGCCGGTTTTCTCTACGTTCGCTCTGAACATCAGGTC
AAACTGGAACCACTGGTGGTAAGTTGGGGATGGCAGCCACCCACCCCACTCCAGGGCAGTTTTCTTGCCTACCCAGAGGG
ACGGCCACTACAGGCGTATTACGAATGGATGGGCACCGATGACCCTTCGGCATTTCTCACTGTCCCGGCAGCCATCGAAT
TTCAACGTCGCCACAACTGGAGCGCAATGCGGCTGGCGTGCCACGAACTTTTGCGTACCGCCTCGCAGCACATCCTCGCA
CTCAGCGATATACCACCGCTTACCCCTGACGATCCAGGCTGGTGGGTGCAGATGCGGGCACTGCCCCTGCCACCGTGCGA
TCCGACACTGGTTCAGTCCCGCCTCTGGCGCGAGTGGCGAATTGAGGTACCATGTTTCACCTGGGAAGGACGACCGTTGA
TCCGCGTCTCCATCCAGGTCTACAATACACCGGCAGATGTTGAGCGATTGTTGACCGGCCTGCAAGCCGTACTGAGCACA
TCATGA

Upstream 100 bases:

>100_bases
GGAATTAGGGCGAGGTTGTATGATCAGGGGGTTGATCATCTGCTCGCCATTTATCGGCGATAATAGAGGCTGACACTACA
ACCACGATCAAGGATCGACC

Downstream 100 bases:

>100_bases
TAGACATCGACCACGTAAGCTACACCTATCCCGGCGCTACCGAACCGATCTTACGCAACCTGAGTCTTCAGATTGCACCG
GGCGAATTCTTGCTGGTTTG

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTATTCSLPIPELAEQFLLRRDMTFLNHGSFGACPQPVFAVYQQWQRTLEAQPVEFLGRRLSDLLYRARSELAAFVGAAA
EDVVFVPNVTYALNIVARSLDLQPGDEVLGITHEYGAIERTWRYVCLQRGATYRNQPVELPVTTSDEIIDQIWQGVTPRT
RVMLISHITSPTAIVMPVAEVCRRARAAGILTVIDGAHAPGQIDLNLHELAPDFYAGNCHKWLCAPKGAGFLYVRSEHQV
KLEPLVVSWGWQPPTPLQGSFLAYPEGRPLQAYYEWMGTDDPSAFLTVPAAIEFQRRHNWSAMRLACHELLRTASQHILA
LSDIPPLTPDDPGWWVQMRALPLPPCDPTLVQSRLWREWRIEVPCFTWEGRPLIRVSIQVYNTPADVERLLTGLQAVLST
S

Sequences:

>Translated_401_residues
MTATTCSLPIPELAEQFLLRRDMTFLNHGSFGACPQPVFAVYQQWQRTLEAQPVEFLGRRLSDLLYRARSELAAFVGAAA
EDVVFVPNVTYALNIVARSLDLQPGDEVLGITHEYGAIERTWRYVCLQRGATYRNQPVELPVTTSDEIIDQIWQGVTPRT
RVMLISHITSPTAIVMPVAEVCRRARAAGILTVIDGAHAPGQIDLNLHELAPDFYAGNCHKWLCAPKGAGFLYVRSEHQV
KLEPLVVSWGWQPPTPLQGSFLAYPEGRPLQAYYEWMGTDDPSAFLTVPAAIEFQRRHNWSAMRLACHELLRTASQHILA
LSDIPPLTPDDPGWWVQMRALPLPPCDPTLVQSRLWREWRIEVPCFTWEGRPLIRVSIQVYNTPADVERLLTGLQAVLST
S
>Mature_400_residues
TATTCSLPIPELAEQFLLRRDMTFLNHGSFGACPQPVFAVYQQWQRTLEAQPVEFLGRRLSDLLYRARSELAAFVGAAAE
DVVFVPNVTYALNIVARSLDLQPGDEVLGITHEYGAIERTWRYVCLQRGATYRNQPVELPVTTSDEIIDQIWQGVTPRTR
VMLISHITSPTAIVMPVAEVCRRARAAGILTVIDGAHAPGQIDLNLHELAPDFYAGNCHKWLCAPKGAGFLYVRSEHQVK
LEPLVVSWGWQPPTPLQGSFLAYPEGRPLQAYYEWMGTDDPSAFLTVPAAIEFQRRHNWSAMRLACHELLRTASQHILAL
SDIPPLTPDDPGWWVQMRALPLPPCDPTLVQSRLWREWRIEVPCFTWEGRPLIRVSIQVYNTPADVERLLTGLQAVLSTS

Specific function: Catalyzes the reversible isomerization between isopenicillin N and penicillin N [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=378, Percent_Identity=26.7195767195767, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789175, Length=229, Percent_Identity=28.3842794759825, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25143064, Length=192, Percent_Identity=23.9583333333333, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =5.1.1.17 [H]

Molecular weight: Translated: 45113; Mature: 44982

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATTCSLPIPELAEQFLLRRDMTFLNHGSFGACPQPVFAVYQQWQRTLEAQPVEFLGRR
CCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
LSDLLYRARSELAAFVGAAAEDVVFVPNVTYALNIVARSLDLQPGDEVLGITHEYGAIER
HHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCEEEEEHHCCCHHH
TWRYVCLQRGATYRNQPVELPVTTSDEIIDQIWQGVTPRTRVMLISHITSPTAIVMPVAE
HHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHCCCCCCHHEEEEECCCCCCCHHHHHHH
VCRRARAAGILTVIDGAHAPGQIDLNLHELAPDFYAGNCHKWLCAPKGAGFLYVRSEHQV
HHHHHHHCCEEEEECCCCCCCEEEEEHHHHCCCCCCCCCCEEEECCCCCCEEEEECCCCE
KLEPLVVSWGWQPPTPLQGSFLAYPEGRPLQAYYEWMGTDDPSAFLTVPAAIEFQRRHNW
EEEEEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHCCCCCCCEEEEECHHEEHHHHCCC
SAMRLACHELLRTASQHILALSDIPPLTPDDPGWWVQMRALPLPPCDPTLVQSRLWREWR
HHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHE
IEVPCFTWEGRPLIRVSIQVYNTPADVERLLTGLQAVLSTS
EECCEEEECCCEEEEEEEEEECCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TATTCSLPIPELAEQFLLRRDMTFLNHGSFGACPQPVFAVYQQWQRTLEAQPVEFLGRR
CCCCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
LSDLLYRARSELAAFVGAAAEDVVFVPNVTYALNIVARSLDLQPGDEVLGITHEYGAIER
HHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCEEEEEHHCCCHHH
TWRYVCLQRGATYRNQPVELPVTTSDEIIDQIWQGVTPRTRVMLISHITSPTAIVMPVAE
HHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHCCCCCCHHEEEEECCCCCCCHHHHHHH
VCRRARAAGILTVIDGAHAPGQIDLNLHELAPDFYAGNCHKWLCAPKGAGFLYVRSEHQV
HHHHHHHCCEEEEECCCCCCCEEEEEHHHHCCCCCCCCCCEEEECCCCCCEEEEECCCCE
KLEPLVVSWGWQPPTPLQGSFLAYPEGRPLQAYYEWMGTDDPSAFLTVPAAIEFQRRHNW
EEEEEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHCCCCCCCEEEEECHHEEHHHHCCC
SAMRLACHELLRTASQHILALSDIPPLTPDDPGWWVQMRALPLPPCDPTLVQSRLWREWR
HHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHE
IEVPCFTWEGRPLIRVSIQVYNTPADVERLLTGLQAVLSTS
EECCEEEECCCEEEEEEEEEECCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8437592 [H]