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The map label for this gene is appC [H]

Identifier: 222525029

GI number: 222525029

Start: 2231341

End: 2232333

Strand: Direct

Name: appC [H]

Synonym: Chy400_1765

Alternate gene names: 222525029

Gene position: 2231341-2232333 (Clockwise)

Preceding gene: 222525028

Following gene: 222525030

Centisome position: 42.35

GC content: 55.69

Gene sequence:

>993_bases
ATGGCCACCAGCACGACTGCCGTGCCGCTTGAAGAGGCCGCACCCCGACGGTCGGAGGGGCAATGGGCGATTGTCTTTCG
CCGTTTCCGCCGTCACCGTCTGGCGATGTTTTGTGTCGGCCTCCTGACAGTGTTACTTCTGTTGTCGGCGCTAGCGCCGT
TAATTGCTCCCTATCCACGCGATGAGCCTAATCTGGGTGGTCGTTTCTTGACACCAATGGGTGTTGATGCTGATGGCGGT
GTCCACGTTCTTGGCACTGACCACCTGGGCCGCGACTATGCCACTCGTCTGCTCTACGCATCACGGGTGTCGCTCGGTAC
GGCCTTCCTGGCTACCGCTGTTGCCTCGACTATCGGTATTTTGTTGGGGATGCTGGCCGGTTATTTCGGTGGCTGGGTTG
ATACGCTCATCAGCCGTTTTCTCGAAATTGTGGCAACATTCCCTACGCTGCTGCTCCTGCTTATTCTGGCCTCAATTCTG
GTGCAGAATATCAATGCTATTCCAATCCCTGACTGGCTGGCATCATTTCTGGCCTTTATGTTTGCCGTCTCAGAACGGGA
AGCCCGCATTATCATTGCCGTGATTATGGTGCTGGCCTTTTTTGGGTGGACGGGAACAGCCCGTTTGATGCGCGGTATGG
TGCTCTCGGTACGTGAGAACGTCTATATCGAGTCGGCGCGTGCTCTGGGCGCCAGTAATGCGCGTATCCTGTTTCGCCAC
GTCTTCCCCAATGCCCTGCCACCGATGATCGTGGACTTTACCCTCGGTGTTAACGGTACGCTGGTGGCAGAGTCAGCGCT
CAGTTTTCTGGGCTTTGGCATTCAAGACCCGACGCCAACATGGGGCAATATGCTGGGCTATGCCCAGAGCTATATGTTTC
AATATCCGTGGATGCCGCTGATTCCGGCACTCCCAATTCTGATTGCTTCGATTGCAATCAACTATATTGGTGATGGGTTG
CGTGATGCGCTCGATCCGCGTCAACGCGGCTAG

Upstream 100 bases:

>100_bases
TTGATCCGCGTATTCGACTGACATAAAGTGCGTTATCATTATGATATGGCGACCGACAATGGCGCCGGTCGTATGCAAGC
ATTTCACGAGGAGAGGTTTG

Downstream 100 bases:

>100_bases
GGAACACGGCGCAAACGCTTGAGGAATAAAGATACGGAGCAACTGTGGCAACCGAGTCTCGTGTTGTAGCGGGTGCAGAG
CGCCCAACCGCCCGCCGTGG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MATSTTAVPLEEAAPRRSEGQWAIVFRRFRRHRLAMFCVGLLTVLLLLSALAPLIAPYPRDEPNLGGRFLTPMGVDADGG
VHVLGTDHLGRDYATRLLYASRVSLGTAFLATAVASTIGILLGMLAGYFGGWVDTLISRFLEIVATFPTLLLLLILASIL
VQNINAIPIPDWLASFLAFMFAVSEREARIIIAVIMVLAFFGWTGTARLMRGMVLSVRENVYIESARALGASNARILFRH
VFPNALPPMIVDFTLGVNGTLVAESALSFLGFGIQDPTPTWGNMLGYAQSYMFQYPWMPLIPALPILIASIAINYIGDGL
RDALDPRQRG

Sequences:

>Translated_330_residues
MATSTTAVPLEEAAPRRSEGQWAIVFRRFRRHRLAMFCVGLLTVLLLLSALAPLIAPYPRDEPNLGGRFLTPMGVDADGG
VHVLGTDHLGRDYATRLLYASRVSLGTAFLATAVASTIGILLGMLAGYFGGWVDTLISRFLEIVATFPTLLLLLILASIL
VQNINAIPIPDWLASFLAFMFAVSEREARIIIAVIMVLAFFGWTGTARLMRGMVLSVRENVYIESARALGASNARILFRH
VFPNALPPMIVDFTLGVNGTLVAESALSFLGFGIQDPTPTWGNMLGYAQSYMFQYPWMPLIPALPILIASIAINYIGDGL
RDALDPRQRG
>Mature_329_residues
ATSTTAVPLEEAAPRRSEGQWAIVFRRFRRHRLAMFCVGLLTVLLLLSALAPLIAPYPRDEPNLGGRFLTPMGVDADGGV
HVLGTDHLGRDYATRLLYASRVSLGTAFLATAVASTIGILLGMLAGYFGGWVDTLISRFLEIVATFPTLLLLLILASILV
QNINAIPIPDWLASFLAFMFAVSEREARIIIAVIMVLAFFGWTGTARLMRGMVLSVRENVYIESARALGASNARILFRHV
FPNALPPMIVDFTLGVNGTLVAESALSFLGFGIQDPTPTWGNMLGYAQSYMFQYPWMPLIPALPILIASIAINYIGDGLR
DALDPRQRG

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=329, Percent_Identity=35.258358662614, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1787498, Length=328, Percent_Identity=33.2317073170732, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1787760, Length=329, Percent_Identity=29.483282674772, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1789964, Length=304, Percent_Identity=33.2236842105263, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1789889, Length=271, Percent_Identity=32.1033210332103, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1788505, Length=245, Percent_Identity=30.6122448979592, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787549, Length=311, Percent_Identity=28.6173633440514, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35998; Mature: 35867

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSTTAVPLEEAAPRRSEGQWAIVFRRFRRHRLAMFCVGLLTVLLLLSALAPLIAPYPR
CCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DEPNLGGRFLTPMGVDADGGVHVLGTDHLGRDYATRLLYASRVSLGTAFLATAVASTIGI
CCCCCCCEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGMLAGYFGGWVDTLISRFLEIVATFPTLLLLLILASILVQNINAIPIPDWLASFLAFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
FAVSEREARIIIAVIMVLAFFGWTGTARLMRGMVLSVRENVYIESARALGASNARILFRH
HHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VFPNALPPMIVDFTLGVNGTLVAESALSFLGFGIQDPTPTWGNMLGYAQSYMFQYPWMPL
HCCCCCCCHHEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCH
IPALPILIASIAINYIGDGLRDALDPRQRG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ATSTTAVPLEEAAPRRSEGQWAIVFRRFRRHRLAMFCVGLLTVLLLLSALAPLIAPYPR
CCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DEPNLGGRFLTPMGVDADGGVHVLGTDHLGRDYATRLLYASRVSLGTAFLATAVASTIGI
CCCCCCCEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGMLAGYFGGWVDTLISRFLEIVATFPTLLLLLILASILVQNINAIPIPDWLASFLAFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
FAVSEREARIIIAVIMVLAFFGWTGTARLMRGMVLSVRENVYIESARALGASNARILFRH
HHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VFPNALPPMIVDFTLGVNGTLVAESALSFLGFGIQDPTPTWGNMLGYAQSYMFQYPWMPL
HCCCCCCCHHEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCH
IPALPILIASIAINYIGDGLRDALDPRQRG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]