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The map label for this gene is wecG [H]

Identifier: 222524905

GI number: 222524905

Start: 2067240

End: 2068004

Strand: Reverse

Name: wecG [H]

Synonym: Chy400_1639

Alternate gene names: 222524905

Gene position: 2068004-2067240 (Counterclockwise)

Preceding gene: 222524906

Following gene: 222524904

Centisome position: 39.25

GC content: 53.07

Gene sequence:

>765_bases
ATGAGTTGCCATCGCATTTCAGTACTTAAAACCGTTATTGACCCATTCCCGATCTCGGCTCTCAACCAATACATCGGCGA
GGCCATTGCTTCGCATAAGCAACGAATCATCGCTCATCACAACTTACACAGCGTTTACCTGTATCATCGTGATGCCAAAA
TGCGGATGTTTTACGAACGAGCGGACATTATCCATATTGATGGCATGCCCCTTGTTTACTGGGCGCGCCTGTTAGGCTAT
CCGGTGTCACGTGACCAGCGGGTAACGTACGTTGACTGGATTCAGCCATTGCTGGCAATGGCTACGGCTGAAGGATGGCG
TGTGTTCTACCTCGGTGGTAAACCAGGGGTAGCCGCCCGTGCAGCAGAGATCGTATGCCGGCAATACCCGACACTTACCA
TTGCCACACACCACGGCTATTTTCCGCCGGAAGAGAATGACACAGTATTAGCAACCATTGCCGCCTTTCAGCCCCATATC
TTGCTGGTTGGCATGGGGATGCCGCGTCAAGAACATTGGGTACTGGACAATCTCGACAAGCTTACAGCGAATGCTATTCT
AACTGCTGGAGCATGCTTTGACTATATTGCCGGCGCGATTCCCACGCCACCACGCTGGATGGGGCGTCTGGGGTTAGAGT
GGCTCTATCGCCTCATCAGCGAACCGCGCCGCCTGGGGAAGCGATATCTGATCGAGCCGTGGGCATTGTTACCACTGATG
ATCGCCGATGTACGGAGCGTGTTGCTGAGGAAAGGAAGGAGCTAA

Upstream 100 bases:

>100_bases
AACGCAAAAGACTAGGAAATTTATCACTGATGAATGCCAAAAAATATGATCTTAATCAAATGATTGACGAATATATCAAG
CACCTGTTTATCAAATAAAG

Downstream 100 bases:

>100_bases
TATGCGATTAGCTGCTAATGCTCTACGTAAATCTGCTAAATGGCTGATGACCGGTATGGTTTTTTTACTGGTGCTTATTC
TGTTTTCAGGAAGCCTGGAT

Product: WecB/TagA/CpsF family glycosyl transferase

Products: C55-PP-GlcNAc-ManNAcA; UDP [C]

Alternate protein names: UDP-ManNAcA transferase [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MSCHRISVLKTVIDPFPISALNQYIGEAIASHKQRIIAHHNLHSVYLYHRDAKMRMFYERADIIHIDGMPLVYWARLLGY
PVSRDQRVTYVDWIQPLLAMATAEGWRVFYLGGKPGVAARAAEIVCRQYPTLTIATHHGYFPPEENDTVLATIAAFQPHI
LLVGMGMPRQEHWVLDNLDKLTANAILTAGACFDYIAGAIPTPPRWMGRLGLEWLYRLISEPRRLGKRYLIEPWALLPLM
IADVRSVLLRKGRS

Sequences:

>Translated_254_residues
MSCHRISVLKTVIDPFPISALNQYIGEAIASHKQRIIAHHNLHSVYLYHRDAKMRMFYERADIIHIDGMPLVYWARLLGY
PVSRDQRVTYVDWIQPLLAMATAEGWRVFYLGGKPGVAARAAEIVCRQYPTLTIATHHGYFPPEENDTVLATIAAFQPHI
LLVGMGMPRQEHWVLDNLDKLTANAILTAGACFDYIAGAIPTPPRWMGRLGLEWLYRLISEPRRLGKRYLIEPWALLPLM
IADVRSVLLRKGRS
>Mature_253_residues
SCHRISVLKTVIDPFPISALNQYIGEAIASHKQRIIAHHNLHSVYLYHRDAKMRMFYERADIIHIDGMPLVYWARLLGYP
VSRDQRVTYVDWIQPLLAMATAEGWRVFYLGGKPGVAARAAEIVCRQYPTLTIATHHGYFPPEENDTVLATIAAFQPHIL
LVGMGMPRQEHWVLDNLDKLTANAILTAGACFDYIAGAIPTPPRWMGRLGLEWLYRLISEPRRLGKRYLIEPWALLPLMI
ADVRSVLLRKGRS

Specific function: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in ECA synthesis [H]

COG id: COG1922

COG function: function code M; Teichoic acid biosynthesis proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 26 family [H]

Homologues:

Organism=Escherichia coli, GI2367289, Length=194, Percent_Identity=30.9278350515464, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023085
- InterPro:   IPR004629 [H]

Pfam domain/function: PF03808 Glyco_tran_WecB [H]

EC number: 2.4.1.- [C]

Molecular weight: Translated: 28979; Mature: 28848

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCHRISVLKTVIDPFPISALNQYIGEAIASHKQRIIAHHNLHSVYLYHRDAKMRMFYER
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHH
ADIIHIDGMPLVYWARLLGYPVSRDQRVTYVDWIQPLLAMATAEGWRVFYLGGKPGVAAR
CCEEEECCCHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHH
AAEIVCRQYPTLTIATHHGYFPPEENDTVLATIAAFQPHILLVGMGMPRQEHWVLDNLDK
HHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHH
LTANAILTAGACFDYIAGAIPTPPRWMGRLGLEWLYRLISEPRRLGKRYLIEPWALLPLM
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IADVRSVLLRKGRS
HHHHHHHHHHCCCC
>Mature Secondary Structure 
SCHRISVLKTVIDPFPISALNQYIGEAIASHKQRIIAHHNLHSVYLYHRDAKMRMFYER
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHH
ADIIHIDGMPLVYWARLLGYPVSRDQRVTYVDWIQPLLAMATAEGWRVFYLGGKPGVAAR
CCEEEECCCHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHH
AAEIVCRQYPTLTIATHHGYFPPEENDTVLATIAAFQPHILLVGMGMPRQEHWVLDNLDK
HHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHH
LTANAILTAGACFDYIAGAIPTPPRWMGRLGLEWLYRLISEPRRLGKRYLIEPWALLPLM
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IADVRSVLLRKGRS
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-acetyl-D-mannosaminuronic-acid; undecaprenyl-N-acetyl-alpha-D-glucosaminyl-pyrophosphate [C]

Specific reaction: UDP-N-acetyl-D-mannosaminuronic-acid + undecaprenyl-N-acetyl-alpha-D-glucosaminyl-pyrophosphate = C55-PP-GlcNAc-ManNAcA + UDP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA