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The map label for this gene is arsC [H]

Identifier: 222524719

GI number: 222524719

Start: 1833423

End: 1834184

Strand: Reverse

Name: arsC [H]

Synonym: Chy400_1446

Alternate gene names: 222524719

Gene position: 1834184-1833423 (Counterclockwise)

Preceding gene: 222524720

Following gene: 222524713

Centisome position: 34.81

GC content: 59.71

Gene sequence:

>762_bases
ATGAACTCACAACCTTCTTCCTCAGCACTGAACGGGCTGCGCCTGCTGACCGACGAAACGCGCTGGAAGATCATCCAGTC
CCTGCGCGACAGTGATCGCCAGGTGAGTGAGCTGGTGACGACGCTCGGTCTGGCCCAGAATCTGGTCTCGTATCATCTAC
ACGTGTTGCGTCAGGCTGGCCTGGTACGTGCCCACCGCAGCGACGCTGATGGGCGGGTTGTCTACTACAGCCTCGATCTG
GCAGCGATGGCTGCCCTGCTGACCGGCATCGGTGATGAACTGGCATTGCCGGGCACCCGTCCGCTTGAACTACCGGCGGT
GAAAGTAGCATTCCTGTGCCGCGCCAACAGTGCTCGCTCGCAAATAGCCGAGGCCTGGTTGCGTGTGTTGAGCGATGGTC
AGGTCCAGGCGATGAGTGCTGGAACGCACCCGCAAGCTGTCCATCCGTTAGCCATCACTGTCATGGCAGAGGTAGGGATA
CCGATTGATCAGCAAGTTTCCAAATCGATCACAATGATCATCGATCAGCGTCCTGATCTGATTGTAACGGTGTGTGACAT
TGCGCGCGAGGAGTGTCCGGTGTGGCCAGAGGCCGCCCGCCATATTCACTGGAGTGTAGCCGATCCGGTGGCTATTCAGG
GTACTGCTGATCAGCGGCATGCCGCCTTTGTCGCCGCCCGCGAAGAATTGCGCGAACGGGTGCGGGGCCTGCTGGCGTTA
TTGCCGCGTTGGTTTGGGGGGGGTGCATCACACGATACGTAG

Upstream 100 bases:

>100_bases
TGTGTGTAGCTTGATACTCTTCCCTCTTCCATCTCCTTGCCGAACCAGCCCGGCTCTGGTACGATACGGGCACGCCGTAT
CGCAGAGAGTTTCAAACCCT

Downstream 100 bases:

>100_bases
GGGGTATGCTCAGGATGGGTGTGCAGAAGCTACGCTTCCGCGTCCCCTGTACATCGACCGGATGCGTGTACCTATGATCC
CCCTCTCGCGACTATCAATC

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MNSQPSSSALNGLRLLTDETRWKIIQSLRDSDRQVSELVTTLGLAQNLVSYHLHVLRQAGLVRAHRSDADGRVVYYSLDL
AAMAALLTGIGDELALPGTRPLELPAVKVAFLCRANSARSQIAEAWLRVLSDGQVQAMSAGTHPQAVHPLAITVMAEVGI
PIDQQVSKSITMIIDQRPDLIVTVCDIAREECPVWPEAARHIHWSVADPVAIQGTADQRHAAFVAAREELRERVRGLLAL
LPRWFGGGASHDT

Sequences:

>Translated_253_residues
MNSQPSSSALNGLRLLTDETRWKIIQSLRDSDRQVSELVTTLGLAQNLVSYHLHVLRQAGLVRAHRSDADGRVVYYSLDL
AAMAALLTGIGDELALPGTRPLELPAVKVAFLCRANSARSQIAEAWLRVLSDGQVQAMSAGTHPQAVHPLAITVMAEVGI
PIDQQVSKSITMIIDQRPDLIVTVCDIAREECPVWPEAARHIHWSVADPVAIQGTADQRHAAFVAAREELRERVRGLLAL
LPRWFGGGASHDT
>Mature_253_residues
MNSQPSSSALNGLRLLTDETRWKIIQSLRDSDRQVSELVTTLGLAQNLVSYHLHVLRQAGLVRAHRSDADGRVVYYSLDL
AAMAALLTGIGDELALPGTRPLELPAVKVAFLCRANSARSQIAEAWLRVLSDGQVQAMSAGTHPQAVHPLAITVMAEVGI
PIDQQVSKSITMIIDQRPDLIVTVCDIAREECPVWPEAARHIHWSVADPVAIQGTADQRHAAFVAAREELRERVRGLLAL
LPRWFGGGASHDT

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 27578; Mature: 27578

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSQPSSSALNGLRLLTDETRWKIIQSLRDSDRQVSELVTTLGLAQNLVSYHLHVLRQAG
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVRAHRSDADGRVVYYSLDLAAMAALLTGIGDELALPGTRPLELPAVKVAFLCRANSARS
HHHHHCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHH
QIAEAWLRVLSDGQVQAMSAGTHPQAVHPLAITVMAEVGIPIDQQVSKSITMIIDQRPDL
HHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHEEEECCCCE
IVTVCDIAREECPVWPEAARHIHWSVADPVAIQGTADQRHAAFVAAREELRERVRGLLAL
EEEHHHHHHHHCCCCHHHHHEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
LPRWFGGGASHDT
HHHHHCCCCCCCC
>Mature Secondary Structure
MNSQPSSSALNGLRLLTDETRWKIIQSLRDSDRQVSELVTTLGLAQNLVSYHLHVLRQAG
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVRAHRSDADGRVVYYSLDLAAMAALLTGIGDELALPGTRPLELPAVKVAFLCRANSARS
HHHHHCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHH
QIAEAWLRVLSDGQVQAMSAGTHPQAVHPLAITVMAEVGIPIDQQVSKSITMIIDQRPDL
HHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHEEEECCCCE
IVTVCDIAREECPVWPEAARHIHWSVADPVAIQGTADQRHAAFVAAREELRERVRGLLAL
EEEHHHHHHHHCCCCHHHHHEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
LPRWFGGGASHDT
HHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]