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The map label for this gene is rfbB [C]

Identifier: 222524610

GI number: 222524610

Start: 1706478

End: 1707491

Strand: Reverse

Name: rfbB [C]

Synonym: Chy400_1334

Alternate gene names: 222524610

Gene position: 1707491-1706478 (Counterclockwise)

Preceding gene: 222524611

Following gene: 222524609

Centisome position: 32.41

GC content: 54.04

Gene sequence:

>1014_bases
ATGGTAAATCTACAAACGTTTGCCGGGGCACGGGTGTTGATCACCGGTGGCCTGGGTTTTATCGGCTCAAATCTGGCCCA
TCGCCTGGTTGAACTGGGCGCGAACGTCACTCTGGTCGATTCGCTGATCCCAGAGTACGGCGGGAATCTCTACAACATCG
CCGGAATCGAAGATCGGGTGCGCGTGAACATTGCCGATGTACGCGATGAATACTCGATGAACTATCTGGTGCAGGGGCAG
GATGTGCTCTTTAACCTGGCCGGCCAGACCAGTCATCTCGATTCGATGCGCAATCCGTATATCGATCTCGACATCAATTG
CCGGGCGCAGCTCTCTATCCTCGAAGCGTGCCGTAAACATAATCCAGGCATCACCGTCGTGTATGCCTCAACCCGGCAGA
TTTACGGTAAGCCCAATTACCTGCCGGTAGATGAACGGCATCTTTTGCATCCGGTTGATGTGAATGGCATCAATAAAATG
GCCGGCGAATGGTATCACATTCTCTACAACAATGTCTATGGTATTCGGGCATGCGCCTTACGTCTGACCAACACCTACGG
CCCGCGCATGCGGGTCAAAGACGCGCGCCAGACCTTTCTTGGTATCTGGATCAGGAATGTCATCGAAGGGAAGCCGATCC
AGGTGTGGGGCGATGGTAGTCAGTTACGCGATTTTACCTATATTGATGATTGTGTTGATGCCCTCTTGCTGGCGGCATTG
CATCCGGCAGCAAGCGGACAAATTTTTAATCTAGGCGGGCTTGAAGTCATCAGTCTGCGTGACCTGGCCGCACTGACGGT
TGAAGTGGCCGGCGGGGGCAGCTTTGAGATTATTCCCTATCCAGCCGACCGCAAGCCGATTGATATTGGTGATTACTATG
CCGATGATCGGCGGATCCGCACCATGCTGGGCTGGCAGCCGCGAATTGACCTCCGCACCGGTCTGGCCCGGACTATTGCC
TTCTACCGTGAGCATCGCCACCACTATTGGGATGTGCAGGTAGAAGGAGTTTAA

Upstream 100 bases:

>100_bases
CCGAAGATCTGGCCGGACGCATTTTATCTCTGCCAATGTACCCGGAATTGACGTATGAAGAGATTATGCTGGTTGCCGAG
ACGATTCGAGCGGGGGGGAT

Downstream 100 bases:

>100_bases
CAGGTATCGGTACAATATTCATCAAACCTTCACGATGACAGATTAGAATACAGGCTGAAAAGCAACGAAGGAGCACATCA
TCTATGCGCGTGTTAATTAC

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MVNLQTFAGARVLITGGLGFIGSNLAHRLVELGANVTLVDSLIPEYGGNLYNIAGIEDRVRVNIADVRDEYSMNYLVQGQ
DVLFNLAGQTSHLDSMRNPYIDLDINCRAQLSILEACRKHNPGITVVYASTRQIYGKPNYLPVDERHLLHPVDVNGINKM
AGEWYHILYNNVYGIRACALRLTNTYGPRMRVKDARQTFLGIWIRNVIEGKPIQVWGDGSQLRDFTYIDDCVDALLLAAL
HPAASGQIFNLGGLEVISLRDLAALTVEVAGGGSFEIIPYPADRKPIDIGDYYADDRRIRTMLGWQPRIDLRTGLARTIA
FYREHRHHYWDVQVEGV

Sequences:

>Translated_337_residues
MVNLQTFAGARVLITGGLGFIGSNLAHRLVELGANVTLVDSLIPEYGGNLYNIAGIEDRVRVNIADVRDEYSMNYLVQGQ
DVLFNLAGQTSHLDSMRNPYIDLDINCRAQLSILEACRKHNPGITVVYASTRQIYGKPNYLPVDERHLLHPVDVNGINKM
AGEWYHILYNNVYGIRACALRLTNTYGPRMRVKDARQTFLGIWIRNVIEGKPIQVWGDGSQLRDFTYIDDCVDALLLAAL
HPAASGQIFNLGGLEVISLRDLAALTVEVAGGGSFEIIPYPADRKPIDIGDYYADDRRIRTMLGWQPRIDLRTGLARTIA
FYREHRHHYWDVQVEGV
>Mature_337_residues
MVNLQTFAGARVLITGGLGFIGSNLAHRLVELGANVTLVDSLIPEYGGNLYNIAGIEDRVRVNIADVRDEYSMNYLVQGQ
DVLFNLAGQTSHLDSMRNPYIDLDINCRAQLSILEACRKHNPGITVVYASTRQIYGKPNYLPVDERHLLHPVDVNGINKM
AGEWYHILYNNVYGIRACALRLTNTYGPRMRVKDARQTFLGIWIRNVIEGKPIQVWGDGSQLRDFTYIDDCVDALLLAAL
HPAASGQIFNLGGLEVISLRDLAALTVEVAGGGSFEIIPYPADRKPIDIGDYYADDRRIRTMLGWQPRIDLRTGLARTIA
FYREHRHHYWDVQVEGV

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=325, Percent_Identity=30.4615384615385, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI7657641, Length=336, Percent_Identity=26.7857142857143, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI48994969, Length=352, Percent_Identity=26.9886363636364, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788353, Length=344, Percent_Identity=27.6162790697674, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1788589, Length=352, Percent_Identity=24.7159090909091, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1790049, Length=284, Percent_Identity=27.4647887323944, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17539532, Length=327, Percent_Identity=28.1345565749235, Blast_Score=117, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17568069, Length=330, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115532424, Length=346, Percent_Identity=25.7225433526012, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356223, Length=323, Percent_Identity=29.4117647058824, Blast_Score=118, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37840; Mature: 37840

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNLQTFAGARVLITGGLGFIGSNLAHRLVELGANVTLVDSLIPEYGGNLYNIAGIEDRV
CCEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCEEEECCCCCEE
RVNIADVRDEYSMNYLVQGQDVLFNLAGQTSHLDSMRNPYIDLDINCRAQLSILEACRKH
EEEEECCCCCCCCEEEEECCEEEEEECCCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHC
NPGITVVYASTRQIYGKPNYLPVDERHLLHPVDVNGINKMAGEWYHILYNNVYGIRACAL
CCCEEEEEECCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEEEHHCCCCHHHHEEE
RLTNTYGPRMRVKDARQTFLGIWIRNVIEGKPIQVWGDGSQLRDFTYIDDCVDALLLAAL
EEECCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHH
HPAASGQIFNLGGLEVISLRDLAALTVEVAGGGSFEIIPYPADRKPIDIGDYYADDRRIR
CCCCCCCEEECCCEEEEEECCEEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCHHHH
TMLGWQPRIDLRTGLARTIAFYREHRHHYWDVQVEGV
HHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECC
>Mature Secondary Structure
MVNLQTFAGARVLITGGLGFIGSNLAHRLVELGANVTLVDSLIPEYGGNLYNIAGIEDRV
CCEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCEEEECCCCCEE
RVNIADVRDEYSMNYLVQGQDVLFNLAGQTSHLDSMRNPYIDLDINCRAQLSILEACRKH
EEEEECCCCCCCCEEEEECCEEEEEECCCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHC
NPGITVVYASTRQIYGKPNYLPVDERHLLHPVDVNGINKMAGEWYHILYNNVYGIRACAL
CCCEEEEEECCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEEEHHCCCCHHHHEEE
RLTNTYGPRMRVKDARQTFLGIWIRNVIEGKPIQVWGDGSQLRDFTYIDDCVDALLLAAL
EEECCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHH
HPAASGQIFNLGGLEVISLRDLAALTVEVAGGGSFEIIPYPADRKPIDIGDYYADDRRIR
CCCCCCCEEECCCEEEEEECCEEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCHHHH
TMLGWQPRIDLRTGLARTIAFYREHRHHYWDVQVEGV
HHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]