Click here to switch to the map view.

The map label for this gene is yfbG [C]

Identifier: 222524609

GI number: 222524609

Start: 1705444

End: 1706394

Strand: Reverse

Name: yfbG [C]

Synonym: Chy400_1333

Alternate gene names: 222524609

Gene position: 1706394-1705444 (Counterclockwise)

Preceding gene: 222524610

Following gene: 222524608

Centisome position: 32.39

GC content: 54.99

Gene sequence:

>951_bases
ATGCGCGTGTTAATTACCGGCGGAGCAGGATTTCTCGGTTCACACCTCTGTGATCGTTTTCTGGCTGAAGGTCATACGGT
GATCGCAATGGATAATCTGATCACCGGCAGCACCGACAACATCGCTCATCTGGCCGGACACCCTCGCTTCCTCTTCATTC
ACCACGATGTTACTAATTACATCTATATCGAAGGGCCGATTGACGCCGTGTTGCATTTTGCGTCACCGGCATCGCCAATT
GATTACCTTGAGCTACCGATTCAGACGCTCAAAGTGGGTGCTCTCGGTACGCACAAGGCGCTTGGTCTGGCACGGGCCAA
AGGTGCCCGCTTCCTCCTCGCTTCAACCTCGGAAGTGTACGGCGACCCCCAGGTCCATCCGCAACCCGAAAGTTACTACG
GGCACGTGAATCCGGTCGGGCCGCGCGGCGTCTACGATGAAGCCAAGCGTTTCGCTGAGGCGATGACGATGGCTTATCAC
ACGTATCACGGTGTGGAAACCCGCATTGTTCGCATCTTCAATACCTATGGCCCACGCATGCGGTTGCGTGACGGGCGGGT
CGTGCCCAACTTTATTTCACAGGCACTGCGTGGCGAGCCGCTCACTATCTACGGTGATGGCAGCCAGACCCGTTCGTTCC
AGTACGTTTCCGATCTGGTTGAAGGCGTGTACCGATTGCTCTTCAGTGATGAGGTCGAACCGGTCAATATTGGTAATCCG
GGTGAGTTTACGATAGCCGAGTTTGCCCAGATTGTGAATGAGATCACGGGCAATAAGGCTGGCGTCGTCTACCGCGATCT
GCGCACGAAAGACGACCCTCAAGTGCGGCAACCCGATATTACCAAAGCGCGCCGAATTCTCAATTGGGAACCGAAAGTGA
CGTTGCGCGAAGGCCTAGAGCAGACAATACCCTGGTTCCGGCAGGAACTACAACGACGTGGCGAATTATAA

Upstream 100 bases:

>100_bases
AGGTAGAAGGAGTTTAACAGGTATCGGTACAATATTCATCAAACCTTCACGATGACAGATTAGAATACAGGCTGAAAAGC
AACGAAGGAGCACATCATCT

Downstream 100 bases:

>100_bases
GCACGAGGAGGCGGTACGAAGCGTATGAAGGCGGTCATTCTGGCTGGCGGCTACGGCACCCGGATCAGCGAAGAGAGTGC
CATTCGTCCGAAACCGATGG

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MRVLITGGAGFLGSHLCDRFLAEGHTVIAMDNLITGSTDNIAHLAGHPRFLFIHHDVTNYIYIEGPIDAVLHFASPASPI
DYLELPIQTLKVGALGTHKALGLARAKGARFLLASTSEVYGDPQVHPQPESYYGHVNPVGPRGVYDEAKRFAEAMTMAYH
TYHGVETRIVRIFNTYGPRMRLRDGRVVPNFISQALRGEPLTIYGDGSQTRSFQYVSDLVEGVYRLLFSDEVEPVNIGNP
GEFTIAEFAQIVNEITGNKAGVVYRDLRTKDDPQVRQPDITKARRILNWEPKVTLREGLEQTIPWFRQELQRRGEL

Sequences:

>Translated_316_residues
MRVLITGGAGFLGSHLCDRFLAEGHTVIAMDNLITGSTDNIAHLAGHPRFLFIHHDVTNYIYIEGPIDAVLHFASPASPI
DYLELPIQTLKVGALGTHKALGLARAKGARFLLASTSEVYGDPQVHPQPESYYGHVNPVGPRGVYDEAKRFAEAMTMAYH
TYHGVETRIVRIFNTYGPRMRLRDGRVVPNFISQALRGEPLTIYGDGSQTRSFQYVSDLVEGVYRLLFSDEVEPVNIGNP
GEFTIAEFAQIVNEITGNKAGVVYRDLRTKDDPQVRQPDITKARRILNWEPKVTLREGLEQTIPWFRQELQRRGEL
>Mature_316_residues
MRVLITGGAGFLGSHLCDRFLAEGHTVIAMDNLITGSTDNIAHLAGHPRFLFIHHDVTNYIYIEGPIDAVLHFASPASPI
DYLELPIQTLKVGALGTHKALGLARAKGARFLLASTSEVYGDPQVHPQPESYYGHVNPVGPRGVYDEAKRFAEAMTMAYH
TYHGVETRIVRIFNTYGPRMRLRDGRVVPNFISQALRGEPLTIYGDGSQTRSFQYVSDLVEGVYRLLFSDEVEPVNIGNP
GEFTIAEFAQIVNEITGNKAGVVYRDLRTKDDPQVRQPDITKARRILNWEPKVTLREGLEQTIPWFRQELQRRGEL

Specific function: Unknown

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=310, Percent_Identity=57.0967741935484, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI7657641, Length=328, Percent_Identity=29.2682926829268, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI4507709, Length=323, Percent_Identity=24.1486068111455, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788589, Length=345, Percent_Identity=28.9855072463768, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI48994969, Length=334, Percent_Identity=30.2395209580838, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1788353, Length=340, Percent_Identity=26.4705882352941, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=28.8690476190476, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788366, Length=350, Percent_Identity=26.5714285714286, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17539532, Length=311, Percent_Identity=52.7331189710611, Blast_Score=356, Evalue=1e-98,
Organism=Caenorhabditis elegans, GI115532424, Length=322, Percent_Identity=29.5031055900621, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17568069, Length=325, Percent_Identity=27.3846153846154, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17507723, Length=342, Percent_Identity=26.3157894736842, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI133901786, Length=345, Percent_Identity=26.3768115942029, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI133901790, Length=345, Percent_Identity=26.3768115942029, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI133901788, Length=345, Percent_Identity=26.3768115942029, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17539422, Length=345, Percent_Identity=26.3768115942029, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17539424, Length=345, Percent_Identity=26.3768115942029, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71982035, Length=347, Percent_Identity=23.342939481268, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=353, Percent_Identity=26.0623229461756, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356223, Length=311, Percent_Identity=55.9485530546624, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI19923002, Length=346, Percent_Identity=25.1445086705202, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24158427, Length=340, Percent_Identity=26.7647058823529, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35413; Mature: 35413

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLITGGAGFLGSHLCDRFLAEGHTVIAMDNLITGSTDNIAHLAGHPRFLFIHHDVTNY
CEEEEECCCHHHHHHHHHHHHHCCCEEEEECCEECCCCCCCHHHCCCCEEEEEEECCCCE
IYIEGPIDAVLHFASPASPIDYLELPIQTLKVGALGTHKALGLARAKGARFLLASTSEVY
EEEECHHHHHHHHCCCCCCHHHHHCCHHHHEECCCCCHHHHHHHHCCCCEEEEEECHHHC
GDPQVHPQPESYYGHVNPVGPRGVYDEAKRFAEAMTMAYHTYHGVETRIVRIFNTYGPRM
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCCCCEE
RLRDGRVVPNFISQALRGEPLTIYGDGSQTRSFQYVSDLVEGVYRLLFSDEVEPVNIGNP
EECCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCC
GEFTIAEFAQIVNEITGNKAGVVYRDLRTKDDPQVRQPDITKARRILNWEPKVTLREGLE
CCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHH
QTIPWFRQELQRRGEL
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRVLITGGAGFLGSHLCDRFLAEGHTVIAMDNLITGSTDNIAHLAGHPRFLFIHHDVTNY
CEEEEECCCHHHHHHHHHHHHHCCCEEEEECCEECCCCCCCHHHCCCCEEEEEEECCCCE
IYIEGPIDAVLHFASPASPIDYLELPIQTLKVGALGTHKALGLARAKGARFLLASTSEVY
EEEECHHHHHHHHCCCCCCHHHHHCCHHHHEECCCCCHHHHHHHHCCCCEEEEEECHHHC
GDPQVHPQPESYYGHVNPVGPRGVYDEAKRFAEAMTMAYHTYHGVETRIVRIFNTYGPRM
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCCCCEE
RLRDGRVVPNFISQALRGEPLTIYGDGSQTRSFQYVSDLVEGVYRLLFSDEVEPVNIGNP
EECCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCC
GEFTIAEFAQIVNEITGNKAGVVYRDLRTKDDPQVRQPDITKARRILNWEPKVTLREGLE
CCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHH
QTIPWFRQELQRRGEL
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]