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The map label for this gene is celR [H]

Identifier: 222524543

GI number: 222524543

Start: 1613826

End: 1614875

Strand: Reverse

Name: celR [H]

Synonym: Chy400_1267

Alternate gene names: 222524543

Gene position: 1614875-1613826 (Counterclockwise)

Preceding gene: 222524544

Following gene: 222524542

Centisome position: 30.65

GC content: 50.86

Gene sequence:

>1050_bases
ATGACACTAGAAGAAATTGCGCGCCTTGCCGGTTGTTCACGCTCGACAGTCTCTCGGGTGATTAACCACGATCCACATGT
GAGTCCAGAAATGCGAGAGCGAGTATGGCAAATCATTAAAGAGCACGATTTTCAGCCTAATCTTGCAGCACGCGCATTAG
CTGGTCGTCGCAGTCGAGTCATCGGTCTGGTCATACCTCATCCACTCAGCACGATTTTTACCGATCCGTATTTTTCAGTA
TTGATTCAGGGGTGTGCAAAGGCATGTGATGAGCGTGGGTATTATTTGATGCTATCACTGGTGCTACGACAAGAAGACGA
CACCTATCAATGGTTAATTCACGCTCGACACATAGATGGTCTGCTTCTGGCACCACCGTTGATGGATGACCCGTTCGTGC
AGCATTTGTTGGCCAAACGACTGCCGCTTGTCATGATCGGTCGAATTCCTGGTCGCACAGATATTTCTTCGGTGAATGTT
GATAACCTCAAAGGCGCTATCCTGGCTACGCAGCATCTGTTGAAGCTTGGCTACTCGAAGATTGCCACTATTACCGGTTT
AATGAGCCTGGTCGGCGCCTATGATCGCCTGGAAGGCTATCTGTGTGCGCTGCGCGAGGCGGGTATCGAGCCGCATCCGG
AATATATTCAGGGGGGCGATTGGTCAGAAGCCAGCGGAAAGTACGCTATGCAACGCCTATTGCAGGTTACCCCTCGGCCT
GATGCCGTGTTTGCTGCCAATGACAGCATGGCTGTCGGCGCGATAAAAGCAATCCAGGCGGCGGGGTTGAAGGTTCCTGA
TGATATTGCCGTAGTGGGATTTGATAACTTGCCGGTAGCGACAACGATTGATCCGCCTCTGACTACGGTACATCATCCAA
TTGAGCAGATCGGCTTTCTGGCTGCTGCTACGCTAATTGAACAGTTAGAGACCTGTACAACCCAGGCGGCGAAAGTTAGT
GTTCAGCATATTGTCCTACCTACCAGGTTGATTGTTCGTATGTCTTGTGGAGCAGCGCTGCGACGTAGCACTCATCCCAA
GACTCATTAA

Upstream 100 bases:

>100_bases
GCAAGATGATCAGCATTTTGTGGGTATTTACCAACAAACAACACAACAAGCATACAGTGCTGATGTACTCGCAATTCGTT
TCTACCAAATGGAGATACAG

Downstream 100 bases:

>100_bases
GGATTCGGAACGCAAGATAAAAAACAAGGAGGTGAACCAGGCCAGGACTACCAGGAGTAAATGTTGTACCTTATCGATTT
ATTTCCATGTTTTGGATCCC

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MTLEEIARLAGCSRSTVSRVINHDPHVSPEMRERVWQIIKEHDFQPNLAARALAGRRSRVIGLVIPHPLSTIFTDPYFSV
LIQGCAKACDERGYYLMLSLVLRQEDDTYQWLIHARHIDGLLLAPPLMDDPFVQHLLAKRLPLVMIGRIPGRTDISSVNV
DNLKGAILATQHLLKLGYSKIATITGLMSLVGAYDRLEGYLCALREAGIEPHPEYIQGGDWSEASGKYAMQRLLQVTPRP
DAVFAANDSMAVGAIKAIQAAGLKVPDDIAVVGFDNLPVATTIDPPLTTVHHPIEQIGFLAAATLIEQLETCTTQAAKVS
VQHIVLPTRLIVRMSCGAALRRSTHPKTH

Sequences:

>Translated_349_residues
MTLEEIARLAGCSRSTVSRVINHDPHVSPEMRERVWQIIKEHDFQPNLAARALAGRRSRVIGLVIPHPLSTIFTDPYFSV
LIQGCAKACDERGYYLMLSLVLRQEDDTYQWLIHARHIDGLLLAPPLMDDPFVQHLLAKRLPLVMIGRIPGRTDISSVNV
DNLKGAILATQHLLKLGYSKIATITGLMSLVGAYDRLEGYLCALREAGIEPHPEYIQGGDWSEASGKYAMQRLLQVTPRP
DAVFAANDSMAVGAIKAIQAAGLKVPDDIAVVGFDNLPVATTIDPPLTTVHHPIEQIGFLAAATLIEQLETCTTQAAKVS
VQHIVLPTRLIVRMSCGAALRRSTHPKTH
>Mature_348_residues
TLEEIARLAGCSRSTVSRVINHDPHVSPEMRERVWQIIKEHDFQPNLAARALAGRRSRVIGLVIPHPLSTIFTDPYFSVL
IQGCAKACDERGYYLMLSLVLRQEDDTYQWLIHARHIDGLLLAPPLMDDPFVQHLLAKRLPLVMIGRIPGRTDISSVNVD
NLKGAILATQHLLKLGYSKIATITGLMSLVGAYDRLEGYLCALREAGIEPHPEYIQGGDWSEASGKYAMQRLLQVTPRPD
AVFAANDSMAVGAIKAIQAAGLKVPDDIAVVGFDNLPVATTIDPPLTTVHHPIEQIGFLAAATLIEQLETCTTQAAKVSV
QHIVLPTRLIVRMSCGAALRRSTHPKTH

Specific function: Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=329, Percent_Identity=37.0820668693009, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1790369, Length=348, Percent_Identity=32.7586206896552, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1787948, Length=338, Percent_Identity=31.6568047337278, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1789068, Length=300, Percent_Identity=31.6666666666667, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1789202, Length=295, Percent_Identity=32.8813559322034, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1788474, Length=306, Percent_Identity=33.0065359477124, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786540, Length=351, Percent_Identity=31.6239316239316, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1787580, Length=335, Percent_Identity=27.7611940298507, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1787906, Length=346, Percent_Identity=26.0115606936416, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786268, Length=285, Percent_Identity=27.719298245614, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI48994940, Length=316, Percent_Identity=27.8481012658228, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1790715, Length=316, Percent_Identity=26.2658227848101, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1790689, Length=335, Percent_Identity=27.1641791044776, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789456, Length=308, Percent_Identity=25.974025974026, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790192, Length=221, Percent_Identity=28.0542986425339, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38342; Mature: 38211

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLEEIARLAGCSRSTVSRVINHDPHVSPEMRERVWQIIKEHDFQPNLAARALAGRRSRV
CCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCE
IGLVIPHPLSTIFTDPYFSVLIQGCAKACDERGYYLMLSLVLRQEDDTYQWLIHARHIDG
EEEEECCCHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHEEHHHCCC
LLLAPPLMDDPFVQHLLAKRLPLVMIGRIPGRTDISSVNVDNLKGAILATQHLLKLGYSK
EEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IATITGLMSLVGAYDRLEGYLCALREAGIEPHPEYIQGGDWSEASGKYAMQRLLQVTPRP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
DAVFAANDSMAVGAIKAIQAAGLKVPDDIAVVGFDNLPVATTIDPPLTTVHHPIEQIGFL
CEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEECCCCHHHHHHHHHHHHHH
AAATLIEQLETCTTQAAKVSVQHIVLPTRLIVRMSCGAALRRSTHPKTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TLEEIARLAGCSRSTVSRVINHDPHVSPEMRERVWQIIKEHDFQPNLAARALAGRRSRV
CHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCE
IGLVIPHPLSTIFTDPYFSVLIQGCAKACDERGYYLMLSLVLRQEDDTYQWLIHARHIDG
EEEEECCCHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHEEHHHCCC
LLLAPPLMDDPFVQHLLAKRLPLVMIGRIPGRTDISSVNVDNLKGAILATQHLLKLGYSK
EEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IATITGLMSLVGAYDRLEGYLCALREAGIEPHPEYIQGGDWSEASGKYAMQRLLQVTPRP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
DAVFAANDSMAVGAIKAIQAAGLKVPDDIAVVGFDNLPVATTIDPPLTTVHHPIEQIGFL
CEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEECCCCHHHHHHHHHHHHHH
AAATLIEQLETCTTQAAKVSVQHIVLPTRLIVRMSCGAALRRSTHPKTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10224066 [H]