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The map label for this gene is xylR [H]

Identifier: 222524484

GI number: 222524484

Start: 1539962

End: 1541188

Strand: Direct

Name: xylR [H]

Synonym: Chy400_1208

Alternate gene names: 222524484

Gene position: 1539962-1541188 (Clockwise)

Preceding gene: 222524483

Following gene: 222524485

Centisome position: 29.23

GC content: 54.44

Gene sequence:

>1227_bases
ATGACAACTCTTGGCGAAAAAGCAACCCGTCAGCACACCCGGGACGTCAACTTACGTCTGGTATTGCGGCTTATCTACGA
GCTAGGTGCGGTGAGCCGAGCTGACCTGGCACGTTTGACTAACTTGACGCGAACGACGGTTTCCGATGTTGTAGGAGAAC
TGATAGAACGTGGCTTAGTCATCGAGACCGGATTGGCGACAGGTGGAGGAATAGGGCGTACACCTATGCTCCTGAGCGTT
GCTGAATGGTCACGACCGGTAGCAGCTATTAGTGTCAATGCTGACAGCGTCGAAGGGGCGCTGGTTAGTCTGCGAGGAAA
CGTAGGAAGGCGTATCAGCCGCTCGATTCAGGGGCAGACAGGTGCCGATGCACTAAACACCTTGCAAGAAACTCTTGACG
AGCTGATTCAGACGGCAAACCAGCCACTTCTCGGCATTGGTGTAACCACTCCTGGCTTGATTAACGCCAGTTCGGGAATG
ATTGTCCGCGCAGTCGGACTGGAATGGGCCGATCTACCACTTGGTCAGTTACTCCATGAACGCTACGGCTTACCGGTGAA
GGTGGTCAACGATAGTCAATGCCTGGCTTTAGCTGAGCATCTATTTGGTGAATGGCGAGGTGTAGCCAACTTGGTGGTCC
TGAAGATTGGGAAAGGTGTAGGTGCCGGTATTGTGCTGAATGGTCAACTCTATGCTGGTGAAGGGTTTGGTGCTGGTGAA
ATTGGACACCTGGCCTTTACCGCGAACGGACTGCTTTGCAAGTGTGGAAATCGGGGGTGTCTTGAAACCGTGTTGGGAAG
TGACGCCCTGTTACACCAGGCTCGAACAGCAATTGCTGCCAATCCAAATAGTATTCTCGCAGCATACGCCAGCGATCTAT
CACTCGGGCGGATTGCTGAAGGGGCAGCGATGGGCGACCCGGTTGCCCAGCACGTTATAACAACCGCTGCCGCAGCAACC
GGCGCCGCAGTAGCTACCATTATCAGTCTGTTGTCGGTTCGTCATGTCTTGATTACGGGTCGGATTACCGCCTTCGGAGA
AACGTTTGCTGAGTTAGTGCGTCGTGAAGTGGCACAGCGGGCACTACCAGCCCTGGTACGGGATACTGAGATCAGACTTG
CGCCGGCACCGACCATTACGCCCCTCATTGGCGCAGCAGCCCCAGTCTTGACCGGGGAATTGGGTTTGATTCGTCTTCAC
CGTCGTGAGGAACACGTTGATGCTTGA

Upstream 100 bases:

>100_bases
CTCAATGCTGTGAGAATGGCCAGTTATCCTCTTGACAGGGTTTTATTTGCGTGCTACTATTTTGTTAGTTCATTGGACTA
TCTAATTAAGACGATCTGCT

Downstream 100 bases:

>100_bases
AGCCTTCGCCAATCGTTATCGGATTGAACTGTCCGAGCGTGTCATTCCATTCTGGCTACGCCATTCGCTTGATCATCAGC
ATGGCGGTTATTTCAGCGCA

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MTTLGEKATRQHTRDVNLRLVLRLIYELGAVSRADLARLTNLTRTTVSDVVGELIERGLVIETGLATGGGIGRTPMLLSV
AEWSRPVAAISVNADSVEGALVSLRGNVGRRISRSIQGQTGADALNTLQETLDELIQTANQPLLGIGVTTPGLINASSGM
IVRAVGLEWADLPLGQLLHERYGLPVKVVNDSQCLALAEHLFGEWRGVANLVVLKIGKGVGAGIVLNGQLYAGEGFGAGE
IGHLAFTANGLLCKCGNRGCLETVLGSDALLHQARTAIAANPNSILAAYASDLSLGRIAEGAAMGDPVAQHVITTAAAAT
GAAVATIISLLSVRHVLITGRITAFGETFAELVRREVAQRALPALVRDTEIRLAPAPTITPLIGAAAPVLTGELGLIRLH
RREEHVDA

Sequences:

>Translated_408_residues
MTTLGEKATRQHTRDVNLRLVLRLIYELGAVSRADLARLTNLTRTTVSDVVGELIERGLVIETGLATGGGIGRTPMLLSV
AEWSRPVAAISVNADSVEGALVSLRGNVGRRISRSIQGQTGADALNTLQETLDELIQTANQPLLGIGVTTPGLINASSGM
IVRAVGLEWADLPLGQLLHERYGLPVKVVNDSQCLALAEHLFGEWRGVANLVVLKIGKGVGAGIVLNGQLYAGEGFGAGE
IGHLAFTANGLLCKCGNRGCLETVLGSDALLHQARTAIAANPNSILAAYASDLSLGRIAEGAAMGDPVAQHVITTAAAAT
GAAVATIISLLSVRHVLITGRITAFGETFAELVRREVAQRALPALVRDTEIRLAPAPTITPLIGAAAPVLTGELGLIRLH
RREEHVDA
>Mature_407_residues
TTLGEKATRQHTRDVNLRLVLRLIYELGAVSRADLARLTNLTRTTVSDVVGELIERGLVIETGLATGGGIGRTPMLLSVA
EWSRPVAAISVNADSVEGALVSLRGNVGRRISRSIQGQTGADALNTLQETLDELIQTANQPLLGIGVTTPGLINASSGMI
VRAVGLEWADLPLGQLLHERYGLPVKVVNDSQCLALAEHLFGEWRGVANLVVLKIGKGVGAGIVLNGQLYAGEGFGAGEI
GHLAFTANGLLCKCGNRGCLETVLGSDALLHQARTAIAANPNSILAAYASDLSLGRIAEGAAMGDPVAQHVITTAAAATG
AAVATIISLLSVRHVLITGRITAFGETFAELVRREVAQRALPALVRDTEIRLAPAPTITPLIGAAAPVLTGELGLIRLHR
REEHVDA

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=284, Percent_Identity=28.5211267605634, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI4885285, Length=284, Percent_Identity=28.5211267605634, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI298566315, Length=285, Percent_Identity=28.7719298245614, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI190014632, Length=285, Percent_Identity=28.7719298245614, Blast_Score=102, Evalue=8e-22,
Organism=Escherichia coli, GI1787878, Length=355, Percent_Identity=28.4507042253521, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1786891, Length=358, Percent_Identity=28.2122905027933, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI87082127, Length=358, Percent_Identity=25.1396648044693, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787363, Length=264, Percent_Identity=23.4848484848485, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081733, Length=174, Percent_Identity=29.8850574712644, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 42596; Mature: 42465

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLGEKATRQHTRDVNLRLVLRLIYELGAVSRADLARLTNLTRTTVSDVVGELIERGLV
CCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEE
IETGLATGGGIGRTPMLLSVAEWSRPVAAISVNADSVEGALVSLRGNVGRRISRSIQGQT
EEECCCCCCCCCCCCCEEEHHHCCCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHCCCC
GADALNTLQETLDELIQTANQPLLGIGVTTPGLINASSGMIVRAVGLEWADLPLGQLLHE
CHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEECCCCCEEEEECCCCCCCCHHHHHHH
RYGLPVKVVNDSQCLALAEHLFGEWRGVANLVVLKIGKGVGAGIVLNGQLYAGEGFGAGE
HCCCCEEEECCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCEEEECEEEECCCCCCCC
IGHLAFTANGLLCKCGNRGCLETVLGSDALLHQARTAIAANPNSILAAYASDLSLGRIAE
CCEEEEECCCEEEECCCCCHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHC
GAAMGDPVAQHVITTAAAATGAAVATIISLLSVRHVLITGRITAFGETFAELVRREVAQR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ALPALVRDTEIRLAPAPTITPLIGAAAPVLTGELGLIRLHRREEHVDA
HHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEECCCHHCCCC
>Mature Secondary Structure 
TTLGEKATRQHTRDVNLRLVLRLIYELGAVSRADLARLTNLTRTTVSDVVGELIERGLV
CCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEE
IETGLATGGGIGRTPMLLSVAEWSRPVAAISVNADSVEGALVSLRGNVGRRISRSIQGQT
EEECCCCCCCCCCCCCEEEHHHCCCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHCCCC
GADALNTLQETLDELIQTANQPLLGIGVTTPGLINASSGMIVRAVGLEWADLPLGQLLHE
CHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEECCCCCEEEEECCCCCCCCHHHHHHH
RYGLPVKVVNDSQCLALAEHLFGEWRGVANLVVLKIGKGVGAGIVLNGQLYAGEGFGAGE
HCCCCEEEECCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCEEEECEEEECCCCCCCC
IGHLAFTANGLLCKCGNRGCLETVLGSDALLHQARTAIAANPNSILAAYASDLSLGRIAE
CCEEEEECCCEEEECCCCCHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHC
GAAMGDPVAQHVITTAAAATGAAVATIISLLSVRHVLITGRITAFGETFAELVRREVAQR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ALPALVRDTEIRLAPAPTITPLIGAAAPVLTGELGLIRLHRREEHVDA
HHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8920183 [H]