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The map label for this gene is speA [H]

Identifier: 222524483

GI number: 222524483

Start: 1537650

End: 1539161

Strand: Direct

Name: speA [H]

Synonym: Chy400_1207

Alternate gene names: 222524483

Gene position: 1537650-1539161 (Clockwise)

Preceding gene: 222524482

Following gene: 222524484

Centisome position: 29.18

GC content: 58.53

Gene sequence:

>1512_bases
GTGGTACAGTTGAAGACGCTAACCTTTGCCGACTTGATTGCACAGCAGACCGGCTTTGCCGGTGAGGGCCGCCTGACCGA
TTTCGTGAGCCGTTACGACGGCGACCTCTACTTTGGTGATCGTCTCAACTTGAACCGACTGGTACGCCAACACGGTGCAC
CGCTCGAAGTCGTATACACACCGCAAATTACTGCACAAATTCACCGCATGATCGGCTGGGCCGCGCAGGCTCGTGCCGCT
ACCGAATACGCAGCCCCCTTCCATTACGCCTATGCGACCAAGGCTAACTTTGCTGCCGAGGCGGTGCAAACGGCGTTGGC
GGCTGGTGCTCATTATGAAACCTCGGCAACTGCCGACCTGATCATCGCCCATGGTCTCTGGCGTCAGGGCATCCTGCCAC
CTGATCGACTGATCTGTTGCAACGGCTCAAAGGAGCCGGCCTACCGCAACGCGATCCGGCAATTGCGTCTCGACGGTTGT
GAGACGGTGATACCCGTCCTCGATGATCTCAGTGAATTGCACGATCTGATCACAACGCCGGCACCCTTACAATTTGGTGT
GCGTGAACGTGCCGCCGGAAATCGGGATGGTCGACACCCCGGCAATGATCGTTTTGGCTTGACAATGGCCGAGATCGAAC
AGGCTGCCGATCTGATTGCAACGACTGAACACCGGCTTGTGCTGTACCATGCCATGATCGGCAGCCAGATCGAAGACGAA
GGGCACTTCCTGACCACCCTGCGGGCTTCGATTGAGAACTATTGTCGTCTACGCCGCCGTGTACCAACCCTGCGCTACTT
CAATTTTGGTGGTGGCGTACCAACTGCCGGGTATCAGTTGACGTTCAACTTCGACTACCAGCGTTTTCTTGCCCGGCTGA
TGGCAACGGTGCGCGATCTGTGTGCCGAATACGATGTACCGGTGCCGGAGTTAATCGGTGAATTTGGCCGTTACACCGTC
GCCACCCACAGCGCCTATCTGGTTGAGGTGGGCGCCGTGAAAGCGGGACAACCCGATCAACCAGACTGGTATTTGATCAA
TGGCTCACTGATGGTGATGTTACCGGACACCCTTTTCGTCAGTGGGCAGGAGTTTGTCATCCTGCCGCTCAGCGACTGGC
ATCGGCCAGTGCGTCCAGTACGGCTTGCCGGTCGGCGCACATGCGACAGCGATGACATCTATCCGCGACCGGAACAGCCG
CCATTGTGGTTGCCGGAGACCGATGGCGGTTTGGTCCTGGCCATTTTCGGCATTGGTGCGTACCAGCAGATGATTTCTGG
CCGTGGCGGGGCCCACCACTGTCTGACGCCCGAAGCGGCTCGCTTCATCGTCGAAGAGCGTGATGGGCGTCTCAGTTCAC
GACTGGTGCCACAGCAGGATCAGGCGACTATTATGCGCTTGCTCGGTTATCGTCCGCAGCCGACAGCACTGCCATTGCCA
TTCCGCCAGCCGGCTCGCCCGGCAGTACTCGCTGCCCGCCGGCGTACCCGGGAGCGAATGGTATCGATTTGA

Upstream 100 bases:

>100_bases
GCCGGTGTTCGCTTGTGATCTTGCCCGCTTCTGGTGGGATAGGTCTTATTTTGCCCTGGTTTCGTGGTGCGGGTTGTTCC
CGCTGTATGAATGGAGGAAT

Downstream 100 bases:

>100_bases
GGTAAGGTGATACGATGAGGACAGGTGGCCCATAGAGGCCACCTGTTGGTTTTCATGAGTCCAGACCTCATCCTAAAACC
CGCTGATAATTCAAACCGTG

Product: Orn/DAP/Arg decarboxylase 2

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MVQLKTLTFADLIAQQTGFAGEGRLTDFVSRYDGDLYFGDRLNLNRLVRQHGAPLEVVYTPQITAQIHRMIGWAAQARAA
TEYAAPFHYAYATKANFAAEAVQTALAAGAHYETSATADLIIAHGLWRQGILPPDRLICCNGSKEPAYRNAIRQLRLDGC
ETVIPVLDDLSELHDLITTPAPLQFGVRERAAGNRDGRHPGNDRFGLTMAEIEQAADLIATTEHRLVLYHAMIGSQIEDE
GHFLTTLRASIENYCRLRRRVPTLRYFNFGGGVPTAGYQLTFNFDYQRFLARLMATVRDLCAEYDVPVPELIGEFGRYTV
ATHSAYLVEVGAVKAGQPDQPDWYLINGSLMVMLPDTLFVSGQEFVILPLSDWHRPVRPVRLAGRRTCDSDDIYPRPEQP
PLWLPETDGGLVLAIFGIGAYQQMISGRGGAHHCLTPEAARFIVEERDGRLSSRLVPQQDQATIMRLLGYRPQPTALPLP
FRQPARPAVLAARRRTRERMVSI

Sequences:

>Translated_503_residues
MVQLKTLTFADLIAQQTGFAGEGRLTDFVSRYDGDLYFGDRLNLNRLVRQHGAPLEVVYTPQITAQIHRMIGWAAQARAA
TEYAAPFHYAYATKANFAAEAVQTALAAGAHYETSATADLIIAHGLWRQGILPPDRLICCNGSKEPAYRNAIRQLRLDGC
ETVIPVLDDLSELHDLITTPAPLQFGVRERAAGNRDGRHPGNDRFGLTMAEIEQAADLIATTEHRLVLYHAMIGSQIEDE
GHFLTTLRASIENYCRLRRRVPTLRYFNFGGGVPTAGYQLTFNFDYQRFLARLMATVRDLCAEYDVPVPELIGEFGRYTV
ATHSAYLVEVGAVKAGQPDQPDWYLINGSLMVMLPDTLFVSGQEFVILPLSDWHRPVRPVRLAGRRTCDSDDIYPRPEQP
PLWLPETDGGLVLAIFGIGAYQQMISGRGGAHHCLTPEAARFIVEERDGRLSSRLVPQQDQATIMRLLGYRPQPTALPLP
FRQPARPAVLAARRRTRERMVSI
>Mature_503_residues
MVQLKTLTFADLIAQQTGFAGEGRLTDFVSRYDGDLYFGDRLNLNRLVRQHGAPLEVVYTPQITAQIHRMIGWAAQARAA
TEYAAPFHYAYATKANFAAEAVQTALAAGAHYETSATADLIIAHGLWRQGILPPDRLICCNGSKEPAYRNAIRQLRLDGC
ETVIPVLDDLSELHDLITTPAPLQFGVRERAAGNRDGRHPGNDRFGLTMAEIEQAADLIATTEHRLVLYHAMIGSQIEDE
GHFLTTLRASIENYCRLRRRVPTLRYFNFGGGVPTAGYQLTFNFDYQRFLARLMATVRDLCAEYDVPVPELIGEFGRYTV
ATHSAYLVEVGAVKAGQPDQPDWYLINGSLMVMLPDTLFVSGQEFVILPLSDWHRPVRPVRLAGRRTCDSDDIYPRPEQP
PLWLPETDGGLVLAIFGIGAYQQMISGRGGAHHCLTPEAARFIVEERDGRLSSRLVPQQDQATIMRLLGYRPQPTALPLP
FRQPARPAVLAARRRTRERMVSI

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=328, Percent_Identity=24.0853658536585, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 56166; Mature: 56166

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQLKTLTFADLIAQQTGFAGEGRLTDFVSRYDGDLYFGDRLNLNRLVRQHGAPLEVVYT
CEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEECCCCCHHHHHHHCCCCEEEEEC
PQITAQIHRMIGWAAQARAATEYAAPFHYAYATKANFAAEAVQTALAAGAHYETSATADL
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHH
IIAHGLWRQGILPPDRLICCNGSKEPAYRNAIRQLRLDGCETVIPVLDDLSELHDLITTP
HHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
APLQFGVRERAAGNRDGRHPGNDRFGLTMAEIEQAADLIATTEHRLVLYHAMIGSQIEDE
CCCHHCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCC
GHFLTTLRASIENYCRLRRRVPTLRYFNFGGGVPTAGYQLTFNFDYQRFLARLMATVRDL
CCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
CAEYDVPVPELIGEFGRYTVATHSAYLVEVGAVKAGQPDQPDWYLINGSLMVMLPDTLFV
HHHCCCCHHHHHHHHCCEEEEECCEEEEEECCCCCCCCCCCCEEEECCEEEEEECCEEEE
SGQEFVILPLSDWHRPVRPVRLAGRRTCDSDDIYPRPEQPPLWLPETDGGLVLAIFGIGA
CCCCEEEEECHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCEEEEEECCHH
YQQMISGRGGAHHCLTPEAARFIVEERDGRLSSRLVPQQDQATIMRLLGYRPQPTALPLP
HHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHCCCCCCCCCCCC
FRQPARPAVLAARRRTRERMVSI
CCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVQLKTLTFADLIAQQTGFAGEGRLTDFVSRYDGDLYFGDRLNLNRLVRQHGAPLEVVYT
CEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEECCCCCHHHHHHHCCCCEEEEEC
PQITAQIHRMIGWAAQARAATEYAAPFHYAYATKANFAAEAVQTALAAGAHYETSATADL
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHH
IIAHGLWRQGILPPDRLICCNGSKEPAYRNAIRQLRLDGCETVIPVLDDLSELHDLITTP
HHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
APLQFGVRERAAGNRDGRHPGNDRFGLTMAEIEQAADLIATTEHRLVLYHAMIGSQIEDE
CCCHHCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCC
GHFLTTLRASIENYCRLRRRVPTLRYFNFGGGVPTAGYQLTFNFDYQRFLARLMATVRDL
CCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
CAEYDVPVPELIGEFGRYTVATHSAYLVEVGAVKAGQPDQPDWYLINGSLMVMLPDTLFV
HHHCCCCHHHHHHHHCCEEEEECCEEEEEECCCCCCCCCCCCEEEECCEEEEEECCEEEE
SGQEFVILPLSDWHRPVRPVRLAGRRTCDSDDIYPRPEQPPLWLPETDGGLVLAIFGIGA
CCCCEEEEECHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCEEEEEECCHH
YQQMISGRGGAHHCLTPEAARFIVEERDGRLSSRLVPQQDQATIMRLLGYRPQPTALPLP
HHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHCCCCCCCCCCCC
FRQPARPAVLAARRRTRERMVSI
CCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]