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The map label for this gene is celR [H]

Identifier: 222524457

GI number: 222524457

Start: 1499936

End: 1500964

Strand: Reverse

Name: celR [H]

Synonym: Chy400_1181

Alternate gene names: 222524457

Gene position: 1500964-1499936 (Counterclockwise)

Preceding gene: 222524458

Following gene: 222524456

Centisome position: 28.49

GC content: 55.78

Gene sequence:

>1029_bases
ATGCATATTACCCTTGACGAAATTGCCCGGCGGGCCGGGGTCTCGCGATCAACTGCATCACGGGTTCTCAACAATCACCC
GCATGTGAACCCGGCAGTGCGCGAGCGGGTCTGGCAGGCTATTCGCGAAACCAATTATCAACCAAACCATCCTGCGCGCT
CACTGGCCAGCCGTCGGTCGCAGGTGATTGGGATCATTATTCCGCAGTCGATCCACACCCTGTTCGCCGATCCGTACTTT
CCGCTCTTGATCGAAGGGATTGCCTGTGTCTGTAATGCGCGGGAATTTTCGATCATGCTGGAGCTGGCGACCAATACAAC
TGGCAATCCCTACCGTCATATTGGTCGGCGCGGCTTTCTCGATGGTGCGATCGTAGCATCGGCAATCGAAGATGAATTTC
TGGCGCAATGGCTACAACAAGAAACGCTTCCGGTGGTGTCAGTTGGGCGCATCAGCTCGCATCCGGTTATTCCCTATGTT
GATGTGGACAATCGTCATGGTGCGCGTATGATGGTTGATCACCTGATTCGACGAGGTTACCGCCGGATCGCAACCATTAC
CGGGCCAATGAATATCGTTGCCGGACGAGATCGCTATGCCGGGTATTGTGAAGGGCTGGCCGCTGCCGGATTACCGGTAC
AACCTGAACTCGTCGTCGAGGGCAACTTTAGCGAACAGAGTGGCTTTGCGGCGATGCAGATGCTCTTGCAGCTTGACCCG
CTGCCCGATGCCGTCTTTGCGGCCAGCGATATGATGGCGCTTGGCGCTTTCAAAGCCTTGCGTGCTGCCGATCTGGTTGT
TCCGCGTGATATTGCGTTGACCGGATTTGATGATATTCCGCTCGCCGCAGCAATGACACCGGCGTTAACGACCGTTCGGC
AGCCGATCAATGAACTGGGTCAGACCGCGGCCCGGCTCTTACTCGATCACCTGATTATCGCTTCTTCCGAACCTGCACCA
CAGCGGGTTATTCTGCCTACCGAGCTGATCATTCGTGAAAGTTGCATTCGCGACTCAGAAAGGGGGTGA

Upstream 100 bases:

>100_bases
CGGTTTTGTACAAGTGCTTCGCGCTTTTTGAAAAGCCAGACCTGCTCCTTTTTTGTACTATAAGGCCAGTTGGAAGCGTT
CCCAGTGAGTGGTGGCAGAT

Downstream 100 bases:

>100_bases
AGATACCGCCACATTGCAAAAACTCGTACCCCGACCTGTGTCCAACACAATGGTGTAGTAGTTCCAGAGGAGGAAATGAG
ATGAAGTCGTTCAAAGTCCT

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MHITLDEIARRAGVSRSTASRVLNNHPHVNPAVRERVWQAIRETNYQPNHPARSLASRRSQVIGIIIPQSIHTLFADPYF
PLLIEGIACVCNAREFSIMLELATNTTGNPYRHIGRRGFLDGAIVASAIEDEFLAQWLQQETLPVVSVGRISSHPVIPYV
DVDNRHGARMMVDHLIRRGYRRIATITGPMNIVAGRDRYAGYCEGLAAAGLPVQPELVVEGNFSEQSGFAAMQMLLQLDP
LPDAVFAASDMMALGAFKALRAADLVVPRDIALTGFDDIPLAAAMTPALTTVRQPINELGQTAARLLLDHLIIASSEPAP
QRVILPTELIIRESCIRDSERG

Sequences:

>Translated_342_residues
MHITLDEIARRAGVSRSTASRVLNNHPHVNPAVRERVWQAIRETNYQPNHPARSLASRRSQVIGIIIPQSIHTLFADPYF
PLLIEGIACVCNAREFSIMLELATNTTGNPYRHIGRRGFLDGAIVASAIEDEFLAQWLQQETLPVVSVGRISSHPVIPYV
DVDNRHGARMMVDHLIRRGYRRIATITGPMNIVAGRDRYAGYCEGLAAAGLPVQPELVVEGNFSEQSGFAAMQMLLQLDP
LPDAVFAASDMMALGAFKALRAADLVVPRDIALTGFDDIPLAAAMTPALTTVRQPINELGQTAARLLLDHLIIASSEPAP
QRVILPTELIIRESCIRDSERG
>Mature_342_residues
MHITLDEIARRAGVSRSTASRVLNNHPHVNPAVRERVWQAIRETNYQPNHPARSLASRRSQVIGIIIPQSIHTLFADPYF
PLLIEGIACVCNAREFSIMLELATNTTGNPYRHIGRRGFLDGAIVASAIEDEFLAQWLQQETLPVVSVGRISSHPVIPYV
DVDNRHGARMMVDHLIRRGYRRIATITGPMNIVAGRDRYAGYCEGLAAAGLPVQPELVVEGNFSEQSGFAAMQMLLQLDP
LPDAVFAASDMMALGAFKALRAADLVVPRDIALTGFDDIPLAAAMTPALTTVRQPINELGQTAARLLLDHLIIASSEPAP
QRVILPTELIIRESCIRDSERG

Specific function: Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787580, Length=339, Percent_Identity=31.2684365781711, Blast_Score=184, Evalue=7e-48,
Organism=Escherichia coli, GI1790194, Length=336, Percent_Identity=34.5238095238095, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1787948, Length=346, Percent_Identity=32.9479768786127, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI1790369, Length=340, Percent_Identity=32.0588235294118, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789068, Length=310, Percent_Identity=31.2903225806452, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1788474, Length=343, Percent_Identity=31.4868804664723, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786540, Length=335, Percent_Identity=30.4477611940298, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789202, Length=304, Percent_Identity=31.9078947368421, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787906, Length=352, Percent_Identity=28.6931818181818, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790715, Length=314, Percent_Identity=27.0700636942675, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI48994940, Length=312, Percent_Identity=28.2051282051282, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789456, Length=350, Percent_Identity=27.1428571428571, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1790689, Length=347, Percent_Identity=23.9193083573487, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786268, Length=287, Percent_Identity=24.0418118466899, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37528; Mature: 37528

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHITLDEIARRAGVSRSTASRVLNNHPHVNPAVRERVWQAIRETNYQPNHPARSLASRRS
CCCCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
QVIGIIIPQSIHTLFADPYFPLLIEGIACVCNAREFSIMLELATNTTGNPYRHIGRRGFL
CEEEEEECHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHCCCCC
DGAIVASAIEDEFLAQWLQQETLPVVSVGRISSHPVIPYVDVDNRHGARMMVDHLIRRGY
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
RRIATITGPMNIVAGRDRYAGYCEGLAAAGLPVQPELVVEGNFSEQSGFAAMQMLLQLDP
HHEEEECCCHHEEECCCCHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCC
LPDAVFAASDMMALGAFKALRAADLVVPRDIALTGFDDIPLAAAMTPALTTVRQPINELG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
QTAARLLLDHLIIASSEPAPQRVILPTELIIRESCIRDSERG
HHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MHITLDEIARRAGVSRSTASRVLNNHPHVNPAVRERVWQAIRETNYQPNHPARSLASRRS
CCCCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
QVIGIIIPQSIHTLFADPYFPLLIEGIACVCNAREFSIMLELATNTTGNPYRHIGRRGFL
CEEEEEECHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHCCCCC
DGAIVASAIEDEFLAQWLQQETLPVVSVGRISSHPVIPYVDVDNRHGARMMVDHLIRRGY
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
RRIATITGPMNIVAGRDRYAGYCEGLAAAGLPVQPELVVEGNFSEQSGFAAMQMLLQLDP
HHEEEECCCHHEEECCCCHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCC
LPDAVFAASDMMALGAFKALRAADLVVPRDIALTGFDDIPLAAAMTPALTTVRQPINELG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
QTAARLLLDHLIIASSEPAPQRVILPTELIIRESCIRDSERG
HHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10224066 [H]