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The map label for this gene is ppnK

Identifier: 222524443

GI number: 222524443

Start: 1479949

End: 1480779

Strand: Direct

Name: ppnK

Synonym: Chy400_1167

Alternate gene names: 222524443

Gene position: 1479949-1480779 (Clockwise)

Preceding gene: 222524442

Following gene: 222524444

Centisome position: 28.09

GC content: 57.28

Gene sequence:

>831_bases
ATGCTAGAGCGCGTGGCGGTTCTGTATAACCCCTTGAGCGATGCTTCGATCAAACTATCGCGTGAACTTGCCGACTGGCT
CGTCGAACGGGGTGTGAAAACGACGCGCGGTGTATCGCAGGAGTTCCGCGACCAGCCACATCTGGTGGCAGACTGCGACT
TGATGATCGCGCTGGGAGGTGATGGTACCGTCTTGCGCGCAGCCCGCCTCTGCTTCCCACACAACATCCCGGTCTTGCCG
GTAGCACTCGGACACCTCAGTTTTATGGCCGAAATTGGCCCTGATGAGGTGTATAGCGGTTGTGAACAGATTATGAACGG
TGGCGGCTGGTTTGACGAACGGTCACTGGTGCGAGCACAACTCTGGCGAGGTGGCCAGAAACTCAGCCAACACACCGCAC
TGAATGAGGTCGTGATCTCGCGGAGCGATCTAAGCCGGATTGTGAATGTCCACGTCACCATTGATGACAGCCCGCTCACG
ACCTACCACGCCGATGGCGTGATCGTTGCCACTGCAACCGGCTCGACGGCCTACGCCCTGGCTGCCGGCGGTCCAATCGT
TGATCCGCGTTCGCAGGCGTTGGTGCTGGTGCCAATTGCCGCGCACCTGACTAATATTCCGTCAATGGTTCTACACGAAG
ATGCTGTTGTGACGATGCAGCTTCGCTCGCGCCACCATGCGTTGCTTGCAGTTGATGGACGAGAAAATATTGACCTGATT
GAAGGTGATGAGGTGGTTGTCCGTCGCAGCCCCCAGGTCTGCACCTTTGTCAGGCTCCGTCCAAGTAATCAGTTTTATAC
CCAACTGGTGGCTCGTCTACGGCGTTCGTGA

Upstream 100 bases:

>100_bases
TATCTCCTATCTTCTATCTCCTATCTCCTATCCTCTATCCTCACCCACTCTGCTCAGCTTGTGGTATTCTGATGCAAACA
GGGTGAGAGGAGGTTGAGAC

Downstream 100 bases:

>100_bases
TTGCAGAGGGTCTGCGGTACAGCAATGGCAATCTGTTGATACACCTGTATACATGAGGGGAATGAGCATATGCTGGCCTA
CACAGGCGCAACCGTAAGTG

Product: ATP-NAD/AcoX kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MLERVAVLYNPLSDASIKLSRELADWLVERGVKTTRGVSQEFRDQPHLVADCDLMIALGGDGTVLRAARLCFPHNIPVLP
VALGHLSFMAEIGPDEVYSGCEQIMNGGGWFDERSLVRAQLWRGGQKLSQHTALNEVVISRSDLSRIVNVHVTIDDSPLT
TYHADGVIVATATGSTAYALAAGGPIVDPRSQALVLVPIAAHLTNIPSMVLHEDAVVTMQLRSRHHALLAVDGRENIDLI
EGDEVVVRRSPQVCTFVRLRPSNQFYTQLVARLRRS

Sequences:

>Translated_276_residues
MLERVAVLYNPLSDASIKLSRELADWLVERGVKTTRGVSQEFRDQPHLVADCDLMIALGGDGTVLRAARLCFPHNIPVLP
VALGHLSFMAEIGPDEVYSGCEQIMNGGGWFDERSLVRAQLWRGGQKLSQHTALNEVVISRSDLSRIVNVHVTIDDSPLT
TYHADGVIVATATGSTAYALAAGGPIVDPRSQALVLVPIAAHLTNIPSMVLHEDAVVTMQLRSRHHALLAVDGRENIDLI
EGDEVVVRRSPQVCTFVRLRPSNQFYTQLVARLRRS
>Mature_276_residues
MLERVAVLYNPLSDASIKLSRELADWLVERGVKTTRGVSQEFRDQPHLVADCDLMIALGGDGTVLRAARLCFPHNIPVLP
VALGHLSFMAEIGPDEVYSGCEQIMNGGGWFDERSLVRAQLWRGGQKLSQHTALNEVVISRSDLSRIVNVHVTIDDSPLT
TYHADGVIVATATGSTAYALAAGGPIVDPRSQALVLVPIAAHLTNIPSMVLHEDAVVTMQLRSRHHALLAVDGRENIDLI
EGDEVVVRRSPQVCTFVRLRPSNQFYTQLVARLRRS

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family

Homologues:

Organism=Homo sapiens, GI55743112, Length=296, Percent_Identity=28.7162162162162, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1788968, Length=216, Percent_Identity=29.6296296296296, Blast_Score=114, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6320794, Length=216, Percent_Identity=32.8703703703704, Blast_Score=112, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6322509, Length=307, Percent_Identity=29.3159609120521, Blast_Score=111, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6325068, Length=235, Percent_Identity=29.7872340425532, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI161077047, Length=250, Percent_Identity=29.2, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573832, Length=250, Percent_Identity=29.2, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573826, Length=250, Percent_Identity=29.2, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573830, Length=250, Percent_Identity=29.2, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573828, Length=259, Percent_Identity=28.957528957529, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281363321, Length=264, Percent_Identity=26.1363636363636, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363323, Length=264, Percent_Identity=26.1363636363636, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24653424, Length=264, Percent_Identity=26.1363636363636, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653422, Length=264, Percent_Identity=26.1363636363636, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20129957, Length=264, Percent_Identity=26.1363636363636, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPNK_CHLAA (A9WIJ8)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001634687.1
- ProteinModelPortal:   A9WIJ8
- SMR:   A9WIJ8
- GeneID:   5825867
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_1066
- HOGENOM:   HBG713904
- OMA:   CVPEGFD
- ProtClustDB:   CLSK935630
- GO:   GO:0005737
- HAMAP:   MF_00361
- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504
- Gene3D:   G3DSA:2.60.200.30
- Gene3D:   G3DSA:3.40.50.10330
- PANTHER:   PTHR20275

Pfam domain/function: PF01513 NAD_kinase; SSF111331 ATP-NAD_kinase_PpnK-typ

EC number: =2.7.1.23

Molecular weight: Translated: 30253; Mature: 30253

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLERVAVLYNPLSDASIKLSRELADWLVERGVKTTRGVSQEFRDQPHLVADCDLMIALGG
CCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHCCCHHHHCCCCCEEEECEEEEEECC
DGTVLRAARLCFPHNIPVLPVALGHLSFMAEIGPDEVYSGCEQIMNGGGWFDERSLVRAQ
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
LWRGGQKLSQHTALNEVVISRSDLSRIVNVHVTIDDSPLTTYHADGVIVATATGSTAYAL
HHCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCEEEECCCEEEEEECCCCEEEE
AAGGPIVDPRSQALVLVPIAAHLTNIPSMVLHEDAVVTMQLRSRHHALLAVDGRENIDLI
ECCCCCCCCCCCEEEEEEEHHHHCCCCHHHEECCCEEEEEECCCCCEEEEECCCCCCEEE
EGDEVVVRRSPQVCTFVRLRPSNQFYTQLVARLRRS
ECCEEEEECCCCEEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLERVAVLYNPLSDASIKLSRELADWLVERGVKTTRGVSQEFRDQPHLVADCDLMIALGG
CCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHCCCHHHHCCCCCEEEECEEEEEECC
DGTVLRAARLCFPHNIPVLPVALGHLSFMAEIGPDEVYSGCEQIMNGGGWFDERSLVRAQ
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
LWRGGQKLSQHTALNEVVISRSDLSRIVNVHVTIDDSPLTTYHADGVIVATATGSTAYAL
HHCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCEEEECCCEEEEEECCCCEEEE
AAGGPIVDPRSQALVLVPIAAHLTNIPSMVLHEDAVVTMQLRSRHHALLAVDGRENIDLI
ECCCCCCCCCCCEEEEEEEHHHHCCCCHHHEECCCEEEEEECCCCCEEEEECCCCCCEEE
EGDEVVVRRSPQVCTFVRLRPSNQFYTQLVARLRRS
ECCEEEEECCCCEEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA