Click here to switch to the map view.

The map label for this gene is ruvC

Identifier: 222524418

GI number: 222524418

Start: 1444688

End: 1445182

Strand: Direct

Name: ruvC

Synonym: Chy400_1142

Alternate gene names: 222524418

Gene position: 1444688-1445182 (Clockwise)

Preceding gene: 222524417

Following gene: 222524419

Centisome position: 27.42

GC content: 61.82

Gene sequence:

>495_bases
GTGCGTGCGCTTGGTATCGACCCCGGTACGGCTACGATGGGCTGGGGCATCGTTGAGTTCAACAATGGTCATTTGCGCCT
GATCGATGTTGGTGCCTTGACGACGCCTGCCGGTATGCCCCACCCTGAACGGCTCTTGCAGCTCTACAATGGCCTCCGTG
CGATTATTGAGCGCTTGCGCCCGGATACTGCTGCGGTCGAGGAGCTGTTTTTCGGGAAGAATGTCAATACCGCACTGACG
GTTGGTCAGGCGCGCGGGGTGGCCTTACTGGCGCTCGCGCAGGCCGGTATTCCTGTTCACGAGTATAAGCCGCTGGCGGT
GAAGCAGGCAGTGGCAGGCTACGGTGGCGCCGATAAGCGGCAGATGCAGGAGATGGTGCGCCTGACGCTCGGTCTGGCCA
CGATACCCCGCCCCGATGACGCTGCCGATGCGCTGGCGATTGCGATCTGCCACGCCTATACTGCCCCAACTCTCCAGCGC
TTTGGGTTGTCGTGA

Upstream 100 bases:

>100_bases
TCTCGACGACGTGCAGAAGGTGTACTCGAACCTCGATATTACCGCCGAACTGGTTGCGCGCTTCGATGCGTAGCTGGCTG
GCGTTGAACAGGAACAAGCT

Downstream 100 bases:

>100_bases
CATCCCGCGCTGCGTAACGCTGGGACAAGACACAGTTCCTGGTAGTGTTGATAGGTGTATTGCATTATGGTTTCTCGTCG
TCGCCCCGGTGCGCCCGCCG

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MRALGIDPGTATMGWGIVEFNNGHLRLIDVGALTTPAGMPHPERLLQLYNGLRAIIERLRPDTAAVEELFFGKNVNTALT
VGQARGVALLALAQAGIPVHEYKPLAVKQAVAGYGGADKRQMQEMVRLTLGLATIPRPDDAADALAIAICHAYTAPTLQR
FGLS

Sequences:

>Translated_164_residues
MRALGIDPGTATMGWGIVEFNNGHLRLIDVGALTTPAGMPHPERLLQLYNGLRAIIERLRPDTAAVEELFFGKNVNTALT
VGQARGVALLALAQAGIPVHEYKPLAVKQAVAGYGGADKRQMQEMVRLTLGLATIPRPDDAADALAIAICHAYTAPTLQR
FGLS
>Mature_164_residues
MRALGIDPGTATMGWGIVEFNNGHLRLIDVGALTTPAGMPHPERLLQLYNGLRAIIERLRPDTAAVEELFFGKNVNTALT
VGQARGVALLALAQAGIPVHEYKPLAVKQAVAGYGGADKRQMQEMVRLTLGLATIPRPDDAADALAIAICHAYTAPTLQR
FGLS

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=134, Percent_Identity=41.044776119403, Blast_Score=102, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_CHLAA (A9WIH6)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001634665.1
- ProteinModelPortal:   A9WIH6
- SMR:   A9WIH6
- GeneID:   5825844
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_1044
- HOGENOM:   HBG437552
- OMA:   RTGWGVI
- ProtClustDB:   PRK00039
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 17465; Mature: 17465

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALGIDPGTATMGWGIVEFNNGHLRLIDVGALTTPAGMPHPERLLQLYNGLRAIIERLR
CCCCCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
PDTAAVEELFFGKNVNTALTVGQARGVALLALAQAGIPVHEYKPLAVKQAVAGYGGADKR
CCHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHCCCCHHHCCCHHHHHHHHCCCCCCHH
QMQEMVRLTLGLATIPRPDDAADALAIAICHAYTAPTLQRFGLS
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCC
>Mature Secondary Structure
MRALGIDPGTATMGWGIVEFNNGHLRLIDVGALTTPAGMPHPERLLQLYNGLRAIIERLR
CCCCCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
PDTAAVEELFFGKNVNTALTVGQARGVALLALAQAGIPVHEYKPLAVKQAVAGYGGADKR
CCHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHCCCCHHHCCCHHHHHHHHCCCCCCHH
QMQEMVRLTLGLATIPRPDDAADALAIAICHAYTAPTLQRFGLS
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA