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The map label for this gene is bcd [H]

Identifier: 222524403

GI number: 222524403

Start: 1425508

End: 1426677

Strand: Reverse

Name: bcd [H]

Synonym: Chy400_1127

Alternate gene names: 222524403

Gene position: 1426677-1425508 (Counterclockwise)

Preceding gene: 222524404

Following gene: 222524392

Centisome position: 27.08

GC content: 58.89

Gene sequence:

>1170_bases
ATGGAGTACGAGCACAGTGCAGAGATCAAGATGCTGCGACAGGCGGTGCGTGAGTTCGTTGACAAAGAGATTCGCCCGAT
TGCACGTGCCATCGATGAAGAGGAGCGCGTGCCCTTCGAGACGATGAAGAAAGCGGCTGAGCTAGGGTTTCTTGGCGTAC
CCTTCCCCGAACGGTACGGTGGGCTTGAGCTGGGCATTACCGGCTACTGCGTGTTGATGGAAGAACTGAACCGGGTCTGT
GCCAGCCATGCCACCATCATTGGTGCTCATTCGCAACTGGCGGCGATGAGTATCTATCTCGGTGGCACCGAGCAGCAAAA
AGAGACCTACCTTCGTGCCCTGATCGAAGGCCGGAAGTGGGGCGCTTGGGCGCTCACCGAACCCAATGCCGGCTCAGATG
CGGCTCACATTCAGACGACCGCCGAACGACGTGGCGATGAGTGGGTGATCAACGGTCAGAAGATGTGGATCACCAACGGC
AGCTTTGCCGATGTCATCGTGGTCTTTGCCGCAACCGACAAGAACCTCGGTGCGCGTGGTGGTATTACTGCCTTCATCGT
CGAGAAGACCATGCCCGGTTTCCGGGTCGGGAAGGTGGAAGAGAAGATGGGCTTGCGCGCCTCGCACACGGCCAGCCTCT
ACTTCGAGGATTGCCGGGTTCCGGCAGAAAATGTGCTCGGTCAGGTCGGTATGGGCTTTCCGCTCGCGATGCGCACGCTC
GACATCGGGCGCTGTGGGTTGGGCGCAAGCAGCATCGGGTCGGCGAAGGAAGCCTTTGAACTGAGCCGCCGGTACATGGT
TGAGCGCCATCAGTTCGGGCGCCCGATTGCCGAATTTCAGGCGTTGCAATTCAAGCTGGCCGATATGGCGGTGAAGCTCT
ACACCATGGAGCAGATCGTCTACGACTGTGCCCGTCGGGTTGACGCCGGTCAGCAGGCGACGCTCGAAAGCAGCATCGTC
AAGCTCTACTGCACCGAGATGGCCAGCCAGATCATCGACGAGGCGATTCAGATTCACGGTGGCATGGGCTTCTCACGTGA
ACTGCCCCTGGAGCGGATGTACCGCGATGCCCGCGTAACCCGCATCTTTGAGGGTACCAATGAGATTCAGCGCCACGTGA
TTGCCAGCGAGCTGCTCAAGCAGGTTGGTTACAAGGTACGGTTGTATTGA

Upstream 100 bases:

>100_bases
GACTGACCAGTTGGTAGCATCTTCTCTGATCCGTCTTGGGATAGATGGCAGTCAGGTTCGGTTGATGGCAGGTATTGTAT
GAACGAAGGGAGCTACGACA

Downstream 100 bases:

>100_bases
GGGGTCTGGGGGCGGGAACCGGCGGTGACGTATGGTTCCCGCTGCCCCCGTACCTGATCGTGATCACGGCTGCTGCGGCA
GCGTGGCTGCCGCAGCATAC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MEYEHSAEIKMLRQAVREFVDKEIRPIARAIDEEERVPFETMKKAAELGFLGVPFPERYGGLELGITGYCVLMEELNRVC
ASHATIIGAHSQLAAMSIYLGGTEQQKETYLRALIEGRKWGAWALTEPNAGSDAAHIQTTAERRGDEWVINGQKMWITNG
SFADVIVVFAATDKNLGARGGITAFIVEKTMPGFRVGKVEEKMGLRASHTASLYFEDCRVPAENVLGQVGMGFPLAMRTL
DIGRCGLGASSIGSAKEAFELSRRYMVERHQFGRPIAEFQALQFKLADMAVKLYTMEQIVYDCARRVDAGQQATLESSIV
KLYCTEMASQIIDEAIQIHGGMGFSRELPLERMYRDARVTRIFEGTNEIQRHVIASELLKQVGYKVRLY

Sequences:

>Translated_389_residues
MEYEHSAEIKMLRQAVREFVDKEIRPIARAIDEEERVPFETMKKAAELGFLGVPFPERYGGLELGITGYCVLMEELNRVC
ASHATIIGAHSQLAAMSIYLGGTEQQKETYLRALIEGRKWGAWALTEPNAGSDAAHIQTTAERRGDEWVINGQKMWITNG
SFADVIVVFAATDKNLGARGGITAFIVEKTMPGFRVGKVEEKMGLRASHTASLYFEDCRVPAENVLGQVGMGFPLAMRTL
DIGRCGLGASSIGSAKEAFELSRRYMVERHQFGRPIAEFQALQFKLADMAVKLYTMEQIVYDCARRVDAGQQATLESSIV
KLYCTEMASQIIDEAIQIHGGMGFSRELPLERMYRDARVTRIFEGTNEIQRHVIASELLKQVGYKVRLY
>Mature_389_residues
MEYEHSAEIKMLRQAVREFVDKEIRPIARAIDEEERVPFETMKKAAELGFLGVPFPERYGGLELGITGYCVLMEELNRVC
ASHATIIGAHSQLAAMSIYLGGTEQQKETYLRALIEGRKWGAWALTEPNAGSDAAHIQTTAERRGDEWVINGQKMWITNG
SFADVIVVFAATDKNLGARGGITAFIVEKTMPGFRVGKVEEKMGLRASHTASLYFEDCRVPAENVLGQVGMGFPLAMRTL
DIGRCGLGASSIGSAKEAFELSRRYMVERHQFGRPIAEFQALQFKLADMAVKLYTMEQIVYDCARRVDAGQQATLESSIV
KLYCTEMASQIIDEAIQIHGGMGFSRELPLERMYRDARVTRIFEGTNEIQRHVIASELLKQVGYKVRLY

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=371, Percent_Identity=44.2048517520216, Blast_Score=323, Evalue=1e-88,
Organism=Homo sapiens, GI21361497, Length=383, Percent_Identity=40.2088772845953, Blast_Score=275, Evalue=5e-74,
Organism=Homo sapiens, GI4557231, Length=381, Percent_Identity=39.3700787401575, Blast_Score=275, Evalue=7e-74,
Organism=Homo sapiens, GI187960098, Length=381, Percent_Identity=39.3700787401575, Blast_Score=274, Evalue=8e-74,
Organism=Homo sapiens, GI226958412, Length=372, Percent_Identity=40.0537634408602, Blast_Score=274, Evalue=1e-73,
Organism=Homo sapiens, GI226958414, Length=371, Percent_Identity=39.8921832884097, Blast_Score=266, Evalue=2e-71,
Organism=Homo sapiens, GI4501859, Length=368, Percent_Identity=35.8695652173913, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI76496475, Length=381, Percent_Identity=38.8451443569554, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI4557235, Length=381, Percent_Identity=38.8451443569554, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI7656849, Length=377, Percent_Identity=35.8090185676393, Blast_Score=234, Evalue=9e-62,
Organism=Homo sapiens, GI4501857, Length=376, Percent_Identity=33.7765957446808, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI4503943, Length=378, Percent_Identity=29.8941798941799, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI7669494, Length=367, Percent_Identity=29.9727520435967, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI48976061, Length=290, Percent_Identity=32.0689655172414, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI211971008, Length=290, Percent_Identity=32.0689655172414, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI38505218, Length=292, Percent_Identity=26.3698630136986, Blast_Score=112, Evalue=4e-25,
Organism=Escherichia coli, GI87081958, Length=386, Percent_Identity=31.3471502590674, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1786223, Length=387, Percent_Identity=29.7157622739018, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI87081702, Length=358, Percent_Identity=27.0949720670391, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI87082384, Length=273, Percent_Identity=27.8388278388278, Blast_Score=88, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17570075, Length=384, Percent_Identity=39.0625, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=39.2670157068063, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI17534899, Length=383, Percent_Identity=39.686684073107, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI17538396, Length=374, Percent_Identity=38.5026737967914, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI71985184, Length=350, Percent_Identity=40, Blast_Score=256, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17508101, Length=360, Percent_Identity=35.2777777777778, Blast_Score=250, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI17533517, Length=375, Percent_Identity=35.2, Blast_Score=241, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI17506239, Length=370, Percent_Identity=35.1351351351351, Blast_Score=238, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI71985192, Length=307, Percent_Identity=36.4820846905537, Blast_Score=198, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI71990804, Length=303, Percent_Identity=36.3036303630363, Blast_Score=197, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI17534353, Length=378, Percent_Identity=29.3650793650794, Blast_Score=180, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI71982178, Length=270, Percent_Identity=32.962962962963, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=38.7931034482759, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17505929, Length=366, Percent_Identity=26.775956284153, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17551932, Length=367, Percent_Identity=27.2479564032698, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17531909, Length=250, Percent_Identity=30.4, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17562446, Length=286, Percent_Identity=29.020979020979, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17531913, Length=187, Percent_Identity=27.807486631016, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI86563381, Length=316, Percent_Identity=26.2658227848101, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI86563383, Length=316, Percent_Identity=26.2658227848101, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17540842, Length=400, Percent_Identity=23.25, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356377, Length=377, Percent_Identity=41.6445623342175, Blast_Score=301, Evalue=6e-82,
Organism=Drosophila melanogaster, GI24646207, Length=379, Percent_Identity=41.4248021108179, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24660351, Length=369, Percent_Identity=41.7344173441734, Blast_Score=280, Evalue=1e-75,
Organism=Drosophila melanogaster, GI21355753, Length=372, Percent_Identity=40.0537634408602, Blast_Score=262, Evalue=3e-70,
Organism=Drosophila melanogaster, GI281363737, Length=382, Percent_Identity=39.0052356020942, Blast_Score=252, Evalue=4e-67,
Organism=Drosophila melanogaster, GI24666513, Length=371, Percent_Identity=35.3099730458221, Blast_Score=245, Evalue=5e-65,
Organism=Drosophila melanogaster, GI19920834, Length=378, Percent_Identity=30.6878306878307, Blast_Score=174, Evalue=8e-44,
Organism=Drosophila melanogaster, GI221473076, Length=313, Percent_Identity=24.9201277955272, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45550141, Length=313, Percent_Identity=24.9201277955272, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281365206, Length=342, Percent_Identity=26.0233918128655, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24585193, Length=342, Percent_Identity=26.0233918128655, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24585195, Length=342, Percent_Identity=26.0233918128655, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24585191, Length=342, Percent_Identity=26.0233918128655, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 43511; Mature: 43511

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYEHSAEIKMLRQAVREFVDKEIRPIARAIDEEERVPFETMKKAAELGFLGVPFPERYG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHCCCCCCCCCHHHC
GLELGITGYCVLMEELNRVCASHATIIGAHSQLAAMSIYLGGTEQQKETYLRALIEGRKW
CEEECHHHHHHHHHHHHHHHHHHHHEEECCHHHEEEEEEECCCCHHHHHHHHHHHCCCCC
GAWALTEPNAGSDAAHIQTTAERRGDEWVINGQKMWITNGSFADVIVVFAATDKNLGARG
CEEEECCCCCCCCCHHEEEHHHHCCCEEEECCEEEEEECCCCEEEEEEEEECCCCCCCCC
GITAFIVEKTMPGFRVGKVEEKMGLRASHTASLYFEDCRVPAENVLGQVGMGFPLAMRTL
CEEEEEEECCCCCCEECCHHHHHCCCCCCHHHEEEHHCCCCHHHHHHHCCCCCHHHHHHC
DIGRCGLGASSIGSAKEAFELSRRYMVERHQFGRPIAEFQALQFKLADMAVKLYTMEQIV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YDCARRVDAGQQATLESSIVKLYCTEMASQIIDEAIQIHGGMGFSRELPLERMYRDARVT
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
RIFEGTNEIQRHVIASELLKQVGYKVRLY
HHHHCHHHHHHHHHHHHHHHHCCCEEECC
>Mature Secondary Structure
MEYEHSAEIKMLRQAVREFVDKEIRPIARAIDEEERVPFETMKKAAELGFLGVPFPERYG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHCCCCCCCCCHHHC
GLELGITGYCVLMEELNRVCASHATIIGAHSQLAAMSIYLGGTEQQKETYLRALIEGRKW
CEEECHHHHHHHHHHHHHHHHHHHHEEECCHHHEEEEEEECCCCHHHHHHHHHHHCCCCC
GAWALTEPNAGSDAAHIQTTAERRGDEWVINGQKMWITNGSFADVIVVFAATDKNLGARG
CEEEECCCCCCCCCHHEEEHHHHCCCEEEECCEEEEEECCCCEEEEEEEEECCCCCCCCC
GITAFIVEKTMPGFRVGKVEEKMGLRASHTASLYFEDCRVPAENVLGQVGMGFPLAMRTL
CEEEEEEECCCCCCEECCHHHHHCCCCCCHHHEEEHHCCCCHHHHHHHCCCCCHHHHHHC
DIGRCGLGASSIGSAKEAFELSRRYMVERHQFGRPIAEFQALQFKLADMAVKLYTMEQIV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YDCARRVDAGQQATLESSIVKLYCTEMASQIIDEAIQIHGGMGFSRELPLERMYRDARVT
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
RIFEGTNEIQRHVIASELLKQVGYKVRLY
HHHHCHHHHHHHHHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]