Click here to switch to the map view.

The map label for this gene is cycZ [H]

Identifier: 222524303

GI number: 222524303

Start: 1305301

End: 1306257

Strand: Reverse

Name: cycZ [H]

Synonym: Chy400_1026

Alternate gene names: 222524303

Gene position: 1306257-1305301 (Counterclockwise)

Preceding gene: 222524304

Following gene: 222524302

Centisome position: 24.79

GC content: 54.02

Gene sequence:

>957_bases
ATGACGCAACGGCTGGCACAGATGGCAAAATTTGGGATCGGCTTGTGGATAGCCGGTGTAATGATTGCCACCTTCCTGAT
AGTTCCCCAATATGAAGGATTAGGTGATGCTGGTCGAATTGTTATTGTCCACGTACCCACTGCGTGGGTTAGCGTGATTG
CCTTTACGATCTCAGCCATCTTCAGTGGCCTCTACCTCTGGCGGCGGCGCGAGCGTGATGATCATATCGCGGTAGCCGCA
GCCGAGGCAGGTCTCCTCTTCACCTTCCTGGCTACTATTACCGGCATGATCTTCTCGCAAGTGGCGTGGGGTATTTTCTG
GAACTGGGATCCCCGCCAGACATCAATCTTTGTTCTTCTCCTCATCTACGCTGCCCTCTTCGCCTTACGCGCAGCGATTG
ACGATGCTGACCGGCGTCGTCAGCTCAGTGCTGTCTATTCACTCTTTGCATTTGTTACGATGCCGTTCCTCTTCTTCGTC
GCGCCACGGATCGCCGATAGTACATTACACCCCAATTGTGCCTTTATTCAGGGCAGCAACTGCGACGGTGTTGTTCTGGA
AGTGGGCAAGGTTGGGTTGATCGGCGATCAGAAGGTGCAGTTACTCGGCCTTGAGCGGCAGGGTAATCTGCTGGTGGCGG
AAGTGAAGGTGAGTACGCCAGGTTTGCAGAGCGAAGCGATTCTCTACCCCAGCCTCGATCTGGTTGACGGTGGGATGGCT
GCCCGCCCTGAGTTTCCCGGTTCGCGTTTCCAGCTTGGGCTTGAAGAGTATAATGAGGCAACCGGTGCGGTGCGGTTGAA
TATGGAAGCCCCTGGCACCAATTTGCTAGAGAATCGCCGCACGCTTTACGTCTTTTTAGCGGCAAATCTGGGCTTTACCG
CACTCTTTTTCTGGATGTTGCAGATACGTTCACAGGTGCTAAACTTACAATGGGCAATTGCCCAGCGGAGGGCCTAA

Upstream 100 bases:

>100_bases
CATAACTGGAACTTACGTTCCTTGTTTTTTAAGCAACAACGTTGTATGATGATCAAAGCAGGGATAGGCTACCACCCGTA
GGGCTAGAAAGCAGTTTGCC

Downstream 100 bases:

>100_bases
CCCATGGATAGCGCAGCAATTTATGTGGCGACAGCCGCTGTGTTGTCGGTCTGGATCACGATCTTTATCTATCTCTGGCG
GATCGATGCGACTGCACGTG

Product: cytochrome c assembly protein

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycZ [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MTQRLAQMAKFGIGLWIAGVMIATFLIVPQYEGLGDAGRIVIVHVPTAWVSVIAFTISAIFSGLYLWRRRERDDHIAVAA
AEAGLLFTFLATITGMIFSQVAWGIFWNWDPRQTSIFVLLLIYAALFALRAAIDDADRRRQLSAVYSLFAFVTMPFLFFV
APRIADSTLHPNCAFIQGSNCDGVVLEVGKVGLIGDQKVQLLGLERQGNLLVAEVKVSTPGLQSEAILYPSLDLVDGGMA
ARPEFPGSRFQLGLEEYNEATGAVRLNMEAPGTNLLENRRTLYVFLAANLGFTALFFWMLQIRSQVLNLQWAIAQRRA

Sequences:

>Translated_318_residues
MTQRLAQMAKFGIGLWIAGVMIATFLIVPQYEGLGDAGRIVIVHVPTAWVSVIAFTISAIFSGLYLWRRRERDDHIAVAA
AEAGLLFTFLATITGMIFSQVAWGIFWNWDPRQTSIFVLLLIYAALFALRAAIDDADRRRQLSAVYSLFAFVTMPFLFFV
APRIADSTLHPNCAFIQGSNCDGVVLEVGKVGLIGDQKVQLLGLERQGNLLVAEVKVSTPGLQSEAILYPSLDLVDGGMA
ARPEFPGSRFQLGLEEYNEATGAVRLNMEAPGTNLLENRRTLYVFLAANLGFTALFFWMLQIRSQVLNLQWAIAQRRA
>Mature_317_residues
TQRLAQMAKFGIGLWIAGVMIATFLIVPQYEGLGDAGRIVIVHVPTAWVSVIAFTISAIFSGLYLWRRRERDDHIAVAAA
EAGLLFTFLATITGMIFSQVAWGIFWNWDPRQTSIFVLLLIYAALFALRAAIDDADRRRQLSAVYSLFAFVTMPFLFFVA
PRIADSTLHPNCAFIQGSNCDGVVLEVGKVGLIGDQKVQLLGLERQGNLLVAEVKVSTPGLQSEAILYPSLDLVDGGMAA
RPEFPGSRFQLGLEEYNEATGAVRLNMEAPGTNLLENRRTLYVFLAANLGFTALFFWMLQIRSQVLNLQWAIAQRRA

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=147, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 35209; Mature: 35077

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRLAQMAKFGIGLWIAGVMIATFLIVPQYEGLGDAGRIVIVHVPTAWVSVIAFTISAI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHH
FSGLYLWRRRERDDHIAVAAAEAGLLFTFLATITGMIFSQVAWGIFWNWDPRQTSIFVLL
HHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHH
LIYAALFALRAAIDDADRRRQLSAVYSLFAFVTMPFLFFVAPRIADSTLHPNCAFIQGSN
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCC
CDGVVLEVGKVGLIGDQKVQLLGLERQGNLLVAEVKVSTPGLQSEAILYPSLDLVDGGMA
CCEEEEEECCEEECCCCEEEEEEEECCCCEEEEEEEECCCCCCCCEEECCCCHHCCCCCC
ARPEFPGSRFQLGLEEYNEATGAVRLNMEAPGTNLLENRRTLYVFLAANLGFTALFFWML
CCCCCCCHHEEECHHHHCCCCCEEEEEECCCCCHHHHCCCEEEEEEECCCCHHHHHHHHH
QIRSQVLNLQWAIAQRRA
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQRLAQMAKFGIGLWIAGVMIATFLIVPQYEGLGDAGRIVIVHVPTAWVSVIAFTISAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHH
FSGLYLWRRRERDDHIAVAAAEAGLLFTFLATITGMIFSQVAWGIFWNWDPRQTSIFVLL
HHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHH
LIYAALFALRAAIDDADRRRQLSAVYSLFAFVTMPFLFFVAPRIADSTLHPNCAFIQGSN
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCC
CDGVVLEVGKVGLIGDQKVQLLGLERQGNLLVAEVKVSTPGLQSEAILYPSLDLVDGGMA
CCEEEEEECCEEECCCCEEEEEEEECCCCEEEEEEEECCCCCCCCEEECCCCHHCCCCCC
ARPEFPGSRFQLGLEEYNEATGAVRLNMEAPGTNLLENRRTLYVFLAANLGFTALFFWML
CCCCCCCHHEEECHHHHCCCCCEEEEEECCCCCHHHHCCCEEEEEEECCCCHHHHHHHHH
QIRSQVLNLQWAIAQRRA
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]