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The map label for this gene is cysS [H]

Identifier: 222524094

GI number: 222524094

Start: 1022152

End: 1023348

Strand: Direct

Name: cysS [H]

Synonym: Chy400_0810

Alternate gene names: 222524094

Gene position: 1022152-1023348 (Clockwise)

Preceding gene: 222524093

Following gene: 222524113

Centisome position: 19.4

GC content: 56.56

Gene sequence:

>1197_bases
ATGCAGCTCTTCAGTACGCTATCACGAACCCGCGAAACCTTCACTGTACCGACCGACCGGCCCGTTACGCTGTATGTTTG
TGGCGTCACCCCTTACGACACTACCCACATGGGTCACGCTCGTACCTTCATTGTCTTTGATGTCCTGGTGCGTTACCTTC
AGTGGCAAGGGGCGACCGTGCGCTACTGTCAGAATGTTACCGATGTTGATGATCCGCTGTTTGAGCGCGCCCGCCGTGAT
GGCGTGCAATGGGATGAGCTGGCCGAACGTCAGATCAGACAACTCCGGGCCGATTGTGCCGACCTGAATATCTTACCCCC
AACCTTCTTCCCGCGGGTTAGTGAAGAGGTTGGCACCATGATCCCCATCATCGAGCGACTGATCGAGCTGGGTCACGCTT
ACGTTGTTGATGGCAATGTCTATTTCAGTATTCAAACCGACCCCGACTTTGGTCGCATGGCCCGTATGGGCTATAGCGAA
TTGCTCGCCATCGCCAACCAGAGAGGGAATAACCCGCATGACCCCAATAAACGCGATCCCCTTGACTTTGTGCTCTGGCA
GCGTGGCAATCCCGACGAACCGAAATGGGAGAGTCCATGGGGGCTGGGGCGACCAGGCTGGCATATCGAGTGTAGTGCAA
TGTCGCAACGCTACCTGGGTGAGCAGATCGATATTCACGGCGGTGGAGCTGATCTGATCTTTCCCCACCATTCATGCGAA
ATTGCCCAGAGTGAATCGGCAACCGGCAAACGGCCCTTTGCCCGCTTCTGGATGCACGTCGGCCTGGTCTGGCTCGACGG
TGAAAAGATGAGTAAGTCGCTAGGGAATCTGGTATTTGCCCGCGATGCCTTACGCGAGCACCATCCCGATGCGATCCGCT
GGTATTTGCTGAGTGAACACTACCGCGAAGATTTTGATTACCGTCGCGATGCCCTCGTGCGCTTCGAGCAATACGCTGCC
GATCTGCGGCAGGCGCTGAGTGTCACCGGCGGCTCGCATAGCCCGCTCGACGTTAGCCGTGGCCGTGAGGACGTCATCGC
CGCAATGAACGATGATCTTGACACCCCAACCGTCCTGGCCGTTCTGCATACGATGGCCGGTATGATCATTGATGGTGCAA
AAGAAGGCCGTGATGTGAGTTCAGCTCAGGCAGTAGTACGCGACCTGGCCTTGATGCTGGGGTTTACACTCCGTTGA

Upstream 100 bases:

>100_bases
TGCATCAAACAACAATATCTGTCTGAGCAATAGTAGTGGTACCATACTATATGAGACTCGAACTAACCATCCTGGATGGT
TTCAGTAAAGGATAGTTCCT

Downstream 100 bases:

>100_bases
GCAGCGCAGGTAGCGAAGCGACCTGATACAGCATATTTACCGCACAGGGTGGGTGAAGACATTTCTTCACCCACCCTTGC
TTCGCGTGCTGTCCATACGC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MQLFSTLSRTRETFTVPTDRPVTLYVCGVTPYDTTHMGHARTFIVFDVLVRYLQWQGATVRYCQNVTDVDDPLFERARRD
GVQWDELAERQIRQLRADCADLNILPPTFFPRVSEEVGTMIPIIERLIELGHAYVVDGNVYFSIQTDPDFGRMARMGYSE
LLAIANQRGNNPHDPNKRDPLDFVLWQRGNPDEPKWESPWGLGRPGWHIECSAMSQRYLGEQIDIHGGGADLIFPHHSCE
IAQSESATGKRPFARFWMHVGLVWLDGEKMSKSLGNLVFARDALREHHPDAIRWYLLSEHYREDFDYRRDALVRFEQYAA
DLRQALSVTGGSHSPLDVSRGREDVIAAMNDDLDTPTVLAVLHTMAGMIIDGAKEGRDVSSAQAVVRDLALMLGFTLR

Sequences:

>Translated_398_residues
MQLFSTLSRTRETFTVPTDRPVTLYVCGVTPYDTTHMGHARTFIVFDVLVRYLQWQGATVRYCQNVTDVDDPLFERARRD
GVQWDELAERQIRQLRADCADLNILPPTFFPRVSEEVGTMIPIIERLIELGHAYVVDGNVYFSIQTDPDFGRMARMGYSE
LLAIANQRGNNPHDPNKRDPLDFVLWQRGNPDEPKWESPWGLGRPGWHIECSAMSQRYLGEQIDIHGGGADLIFPHHSCE
IAQSESATGKRPFARFWMHVGLVWLDGEKMSKSLGNLVFARDALREHHPDAIRWYLLSEHYREDFDYRRDALVRFEQYAA
DLRQALSVTGGSHSPLDVSRGREDVIAAMNDDLDTPTVLAVLHTMAGMIIDGAKEGRDVSSAQAVVRDLALMLGFTLR
>Mature_398_residues
MQLFSTLSRTRETFTVPTDRPVTLYVCGVTPYDTTHMGHARTFIVFDVLVRYLQWQGATVRYCQNVTDVDDPLFERARRD
GVQWDELAERQIRQLRADCADLNILPPTFFPRVSEEVGTMIPIIERLIELGHAYVVDGNVYFSIQTDPDFGRMARMGYSE
LLAIANQRGNNPHDPNKRDPLDFVLWQRGNPDEPKWESPWGLGRPGWHIECSAMSQRYLGEQIDIHGGGADLIFPHHSCE
IAQSESATGKRPFARFWMHVGLVWLDGEKMSKSLGNLVFARDALREHHPDAIRWYLLSEHYREDFDYRRDALVRFEQYAA
DLRQALSVTGGSHSPLDVSRGREDVIAAMNDDLDTPTVLAVLHTMAGMIIDGAKEGRDVSSAQAVVRDLALMLGFTLR

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=383, Percent_Identity=34.9869451697128, Blast_Score=232, Evalue=5e-61,
Organism=Homo sapiens, GI10835051, Length=334, Percent_Identity=32.6347305389222, Blast_Score=185, Evalue=5e-47,
Organism=Homo sapiens, GI21269877, Length=334, Percent_Identity=32.6347305389222, Blast_Score=185, Evalue=6e-47,
Organism=Homo sapiens, GI303304987, Length=334, Percent_Identity=32.6347305389222, Blast_Score=185, Evalue=6e-47,
Organism=Homo sapiens, GI62240992, Length=334, Percent_Identity=32.6347305389222, Blast_Score=185, Evalue=6e-47,
Organism=Escherichia coli, GI1786737, Length=399, Percent_Identity=41.3533834586466, Blast_Score=317, Evalue=8e-88,
Organism=Caenorhabditis elegans, GI17509795, Length=338, Percent_Identity=32.2485207100592, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17509797, Length=338, Percent_Identity=32.2485207100592, Blast_Score=168, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6324082, Length=334, Percent_Identity=33.2335329341317, Blast_Score=181, Evalue=2e-46,
Organism=Drosophila melanogaster, GI19922218, Length=393, Percent_Identity=33.8422391857506, Blast_Score=214, Evalue=8e-56,
Organism=Drosophila melanogaster, GI19922364, Length=248, Percent_Identity=37.0967741935484, Blast_Score=172, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 45291; Mature: 45291

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLFSTLSRTRETFTVPTDRPVTLYVCGVTPYDTTHMGHARTFIVFDVLVRYLQWQGATV
CCHHHHHHHHHCEEECCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHH
RYCQNVTDVDDPLFERARRDGVQWDELAERQIRQLRADCADLNILPPTFFPRVSEEVGTM
HHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
IPIIERLIELGHAYVVDGNVYFSIQTDPDFGRMARMGYSELLAIANQRGNNPHDPNKRDP
HHHHHHHHHCCCEEEECCEEEEEEECCCCHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCC
LDFVLWQRGNPDEPKWESPWGLGRPGWHIECSAMSQRYLGEQIDIHGGGADLIFPHHSCE
CEEEEECCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCCEEEECCCCCC
IAQSESATGKRPFARFWMHVGLVWLDGEKMSKSLGNLVFARDALREHHPDAIRWYLLSEH
CCCCCCCCCCCHHHHHHHHHCEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
YREDFDYRRDALVRFEQYAADLRQALSVTGGSHSPLDVSRGREDVIAAMNDDLDTPTVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHCCCCCCHHHHH
VLHTMAGMIIDGAKEGRDVSSAQAVVRDLALMLGFTLR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQLFSTLSRTRETFTVPTDRPVTLYVCGVTPYDTTHMGHARTFIVFDVLVRYLQWQGATV
CCHHHHHHHHHCEEECCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHH
RYCQNVTDVDDPLFERARRDGVQWDELAERQIRQLRADCADLNILPPTFFPRVSEEVGTM
HHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
IPIIERLIELGHAYVVDGNVYFSIQTDPDFGRMARMGYSELLAIANQRGNNPHDPNKRDP
HHHHHHHHHCCCEEEECCEEEEEEECCCCHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCC
LDFVLWQRGNPDEPKWESPWGLGRPGWHIECSAMSQRYLGEQIDIHGGGADLIFPHHSCE
CEEEEECCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCCEEEECCCCCC
IAQSESATGKRPFARFWMHVGLVWLDGEKMSKSLGNLVFARDALREHHPDAIRWYLLSEH
CCCCCCCCCCCHHHHHHHHHCEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
YREDFDYRRDALVRFEQYAADLRQALSVTGGSHSPLDVSRGREDVIAAMNDDLDTPTVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHCCCCCCHHHHH
VLHTMAGMIIDGAKEGRDVSSAQAVVRDLALMLGFTLR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA