Click here to switch to the map view.

The map label for this gene is arnC [H]

Identifier: 222523727

GI number: 222523727

Start: 512630

End: 513415

Strand: Reverse

Name: arnC [H]

Synonym: Chy400_0433

Alternate gene names: 222523727

Gene position: 513415-512630 (Counterclockwise)

Preceding gene: 222523728

Following gene: 222523726

Centisome position: 9.74

GC content: 55.85

Gene sequence:

>786_bases
ATGACGACGAACAATGAGCCATTCCTATCCATTGTGATTCCTGCCTACAATGAAGAGCGGCGCTTGCCGGCCACTCTGGC
AGCTATCAAGGCGTTTCTGGTCAACGAACCGTACACTGCCGAAGTGATTGTGGTTGACGACGGCAGTGAGGATCGCACGG
CAGAGGTAGCAGAAGCAGCCGGTGCCACGGTGTTGCGCTGTGAGCATCGTGGCAAGGGATTTGCGGTACGCACCGGTGCT
CTGGCAGCGCGGGGTGACATTATCCTGCTCTGTGATGCTGATCTGGCAACCCCAATCGAAGAATGGCCGCGCTTGCGAGC
GGCAATTGAACGTGGCTATCCCATTGCCATCGGTTCGCGTGAGGGGATAGGGGCATCGCGTGAGGGCGAACCCTGGTATC
GTCACGTGATGGGCCGGGTCTTCAACTGGATTATTCGGCTGGTAGCACTGCGGGGGATTAACGATACCCAGTGTGGTTTT
AAAGCATTACGGCGAGCGGTTGCCCGTGATCTCTTTCAGCGTGTGCGCATTTATGGCGATGATGCGCCGATAGTGCGTGG
GGCAGCAGTGACTGCCTACGATGTTGAACTGCTCTTTTTAGCTCAGCGTCGAGGCTATGCCATTTGCGAAATTCCGGTGA
AATGGCGTTATGGCACCGAGACAAAAGTGAATCCGCTCCGTGACTCTTGGCGGAATCTGCGGGATGTGCTGCGGGTGCGG
ATCAACGATTTGTGTGGAAAGTATGATGTGACATCGACCCCAATTGAGGAGGTTGCTCCACGATGA

Upstream 100 bases:

>100_bases
CATTGCCGCACTTTTGGTCGCGTCGTGCATTCACGCCAGAAGAGGAAGCAGCCCTTGTCGCTGCATTTGAACTTTCGCAA
CCACCAGCACAGAGATTCGT

Downstream 100 bases:

>100_bases
AACCTGCGCAACGTGCATATTTGCGTCGGCTGGCCCATCCGTTGCCGGTCACGGTGATGATTGGCAAGAATGGCTTGACG
GAGGGTATCCTGGCCAAGAT

Product: glycosyl transferase family 2 protein

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTTNNEPFLSIVIPAYNEERRLPATLAAIKAFLVNEPYTAEVIVVDDGSEDRTAEVAEAAGATVLRCEHRGKGFAVRTGA
LAARGDIILLCDADLATPIEEWPRLRAAIERGYPIAIGSREGIGASREGEPWYRHVMGRVFNWIIRLVALRGINDTQCGF
KALRRAVARDLFQRVRIYGDDAPIVRGAAVTAYDVELLFLAQRRGYAICEIPVKWRYGTETKVNPLRDSWRNLRDVLRVR
INDLCGKYDVTSTPIEEVAPR

Sequences:

>Translated_261_residues
MTTNNEPFLSIVIPAYNEERRLPATLAAIKAFLVNEPYTAEVIVVDDGSEDRTAEVAEAAGATVLRCEHRGKGFAVRTGA
LAARGDIILLCDADLATPIEEWPRLRAAIERGYPIAIGSREGIGASREGEPWYRHVMGRVFNWIIRLVALRGINDTQCGF
KALRRAVARDLFQRVRIYGDDAPIVRGAAVTAYDVELLFLAQRRGYAICEIPVKWRYGTETKVNPLRDSWRNLRDVLRVR
INDLCGKYDVTSTPIEEVAPR
>Mature_260_residues
TTNNEPFLSIVIPAYNEERRLPATLAAIKAFLVNEPYTAEVIVVDDGSEDRTAEVAEAAGATVLRCEHRGKGFAVRTGAL
AARGDIILLCDADLATPIEEWPRLRAAIERGYPIAIGSREGIGASREGEPWYRHVMGRVFNWIIRLVALRGINDTQCGFK
ALRRAVARDLFQRVRIYGDDAPIVRGAAVTAYDVELLFLAQRRGYAICEIPVKWRYGTETKVNPLRDSWRNLRDVLRVRI
NDLCGKYDVTSTPIEEVAPR

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Homo sapiens, GI7019323, Length=266, Percent_Identity=33.4586466165414, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI215276969, Length=253, Percent_Identity=30.0395256916996, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI4503363, Length=215, Percent_Identity=25.1162790697674, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1788588, Length=174, Percent_Identity=28.735632183908, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25146207, Length=260, Percent_Identity=33.0769230769231, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71999402, Length=233, Percent_Identity=27.4678111587983, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325029, Length=271, Percent_Identity=30.6273062730627, Blast_Score=106, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24582769, Length=270, Percent_Identity=36.2962962962963, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI24585265, Length=241, Percent_Identity=31.9502074688797, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022857
- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.7.8.30 [H]

Molecular weight: Translated: 29211; Mature: 29080

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNNEPFLSIVIPAYNEERRLPATLAAIKAFLVNEPYTAEVIVVDDGSEDRTAEVAEAA
CCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHC
GATVLRCEHRGKGFAVRTGALAARGDIILLCDADLATPIEEWPRLRAAIERGYPIAIGSR
CCEEEEEECCCCCEEEECCCEEECCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEECCC
EGIGASREGEPWYRHVMGRVFNWIIRLVALRGINDTQCGFKALRRAVARDLFQRVRIYGD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
DAPIVRGAAVTAYDVELLFLAQRRGYAICEIPVKWRYGTETKVNPLRDSWRNLRDVLRVR
CCCEEECCEEEEEHHEEEEEECCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
INDLCGKYDVTSTPIEEVAPR
HHHHCCCCCCCCCCHHHHCCC
>Mature Secondary Structure 
TTNNEPFLSIVIPAYNEERRLPATLAAIKAFLVNEPYTAEVIVVDDGSEDRTAEVAEAA
CCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHC
GATVLRCEHRGKGFAVRTGALAARGDIILLCDADLATPIEEWPRLRAAIERGYPIAIGSR
CCEEEEEECCCCCEEEECCCEEECCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEECCC
EGIGASREGEPWYRHVMGRVFNWIIRLVALRGINDTQCGFKALRRAVARDLFQRVRIYGD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
DAPIVRGAAVTAYDVELLFLAQRRGYAICEIPVKWRYGTETKVNPLRDSWRNLRDVLRVR
CCCEEECCEEEEEHHEEEEEECCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
INDLCGKYDVTSTPIEEVAPR
HHHHCCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA