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The map label for this gene is 222523675

Identifier: 222523675

GI number: 222523675

Start: 448161

End: 449786

Strand: Direct

Name: 222523675

Synonym: Chy400_0381

Alternate gene names: NA

Gene position: 448161-449786 (Clockwise)

Preceding gene: 222523672

Following gene: 222523678

Centisome position: 8.51

GC content: 59.1

Gene sequence:

>1626_bases
ATGGAGACCCAACAGCCCGAAACGTTTACAGAGCAGGAAATCGAGCTGCTTCAGCCATTTGTAACCAATGTAGATCGCCC
CATCTTCTGTCTGCGCAACCTACCGGAAGTAGTGAAAGGTGCCCTCTTTGCCCGCTACAGTCGCAGTAGCAAAAGTCTGC
GGCGGCTCTTGCTCGACGAGTTTATCAACGAACCAGAGTCTGGCTTTTCCGCCATGGTATCAGCCCAGGATCACAATCCA
GCAGCACAACTGATCGCTACCCGTCAGGCAGAGGCGTTCTACGACCGGGTGCTCATCGGGTACGGTGACGACTCGGTGGC
TGAACTTGGCGGGGCACATCTGGCGTGTGAGGGGGTGAGCAACATTGCCGCCAAACTGCTCGAAGATAGCCGGCTCGGTA
TCTCACCGCTTGAGAAATCAACCCGCTACGTTCGCTTTGATCGCAAAGGACCGGACGGTTATCCCTACCTGCGCGAACCG
GCCATCATGGCATCGCCATTGGCCGACCGCTATGTCGCGGTGATGGATCATCTCTTCACGACCTACAGTGAATTGCTGGA
ACCTGTTCAGGCGTGGCTCCAACAACAGTACCCGCGTGACGAGGCAACAACCCCGCGTGCGTATCGCAATACTATTCAGG
CCAAAGCGCTTGATCTGTTGCGCGGACTCTTGCCGATGGCAACCCAAACCAATGTCGGCTTATTCGGCAATGGCCGGGCT
TTTGAGTATCTGATCATCAAGCTGGCTGCCTCACCATTTGCCGAAGCGCAGGCGCTGAGCAAGATGATTCAGGCCGAACT
GGATCAGGTCATTCCATCGTTTGTCAAGCGTGCCCGCTCTGACCGTGGGCAGGCGTATGCCGACTATCTTGCGACGACGC
GGGAGCAGGTGGCAGCGCTGGCCCATCAGATACCGGTCGAAGCCGATTCCACCACGCCGGTGACCGTCACGCTGGTTGAT
TACGATCCGCGTGCCGAATGGAAACTCGCCGCAGCCATCCTCTATCCCCACCTCGATCTGCCATTGCCTGCTATCGAAGA
GCTGGTCGCAGCTATGCCGGAAGCAGAACGCCATGCCCTGATCAACGCCGCTGTCGGTGATCGGGCCAACCGCTTCCATC
GTCCCGGTCGGGCATTCGAGGAGCCGTACTACACCTTCGACATCCTGGCCGACATCGGGGCGTATCGCGATCTGCAACGG
CACCGCGTCCTCACCCAGGAACGCCAGCGCTTCACCGTGCGTCATGGCTACGTCACGCCACCAGAACTGGAGGAGATCGG
GGTTGCCGACCGGTACCGAACGGCGCTCGAACAGGCTGCCGACCTGGTCACGGCGCTTGAGGCCACGCTCCCCAACGAAG
CGCAGTATGCAGTACCGCTTGCCTTTCGGGTGCGCTGGCGGATCAAACTCAACCTGCGTGAAGCCTACCACCTGATTGAA
CTCCGCAGCGCCCGGCAAGGCCACCCCAGCTACCGCCAGATCGCACAGCTCATGTTTCGCGAGATCAGCGCCGTCCATCC
CTTCCTGGCGGCTGGAATGCGCTTTGTTGATCACAATGAATACGACCTGGAACGTCTCGCCGCCGAACAACGGATTGATC
AAAAGCGGCAGCAGGTGGGGAGGTGA

Upstream 100 bases:

>100_bases
AATGGTACAATGCCGGCGTTGACCTTCGTTCAATGTTGTATGACCGGCAAGTAATCACCGGCATAACGATATAGACACGC
CGCGTGTCAGAGGAAAACGC

Downstream 100 bases:

>100_bases
GGCCGGCGCATCGCTAACCTTGCAATCAACACAAAAGCCTGATGTCGTGACGACATCAGGCTTTACTGGTGAGCCGGGTG
GGGATCGAACCCACGACCCT

Product: thymidylate synthase complementing protein ThyX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
METQQPETFTEQEIELLQPFVTNVDRPIFCLRNLPEVVKGALFARYSRSSKSLRRLLLDEFINEPESGFSAMVSAQDHNP
AAQLIATRQAEAFYDRVLIGYGDDSVAELGGAHLACEGVSNIAAKLLEDSRLGISPLEKSTRYVRFDRKGPDGYPYLREP
AIMASPLADRYVAVMDHLFTTYSELLEPVQAWLQQQYPRDEATTPRAYRNTIQAKALDLLRGLLPMATQTNVGLFGNGRA
FEYLIIKLAASPFAEAQALSKMIQAELDQVIPSFVKRARSDRGQAYADYLATTREQVAALAHQIPVEADSTTPVTVTLVD
YDPRAEWKLAAAILYPHLDLPLPAIEELVAAMPEAERHALINAAVGDRANRFHRPGRAFEEPYYTFDILADIGAYRDLQR
HRVLTQERQRFTVRHGYVTPPELEEIGVADRYRTALEQAADLVTALEATLPNEAQYAVPLAFRVRWRIKLNLREAYHLIE
LRSARQGHPSYRQIAQLMFREISAVHPFLAAGMRFVDHNEYDLERLAAEQRIDQKRQQVGR

Sequences:

>Translated_541_residues
METQQPETFTEQEIELLQPFVTNVDRPIFCLRNLPEVVKGALFARYSRSSKSLRRLLLDEFINEPESGFSAMVSAQDHNP
AAQLIATRQAEAFYDRVLIGYGDDSVAELGGAHLACEGVSNIAAKLLEDSRLGISPLEKSTRYVRFDRKGPDGYPYLREP
AIMASPLADRYVAVMDHLFTTYSELLEPVQAWLQQQYPRDEATTPRAYRNTIQAKALDLLRGLLPMATQTNVGLFGNGRA
FEYLIIKLAASPFAEAQALSKMIQAELDQVIPSFVKRARSDRGQAYADYLATTREQVAALAHQIPVEADSTTPVTVTLVD
YDPRAEWKLAAAILYPHLDLPLPAIEELVAAMPEAERHALINAAVGDRANRFHRPGRAFEEPYYTFDILADIGAYRDLQR
HRVLTQERQRFTVRHGYVTPPELEEIGVADRYRTALEQAADLVTALEATLPNEAQYAVPLAFRVRWRIKLNLREAYHLIE
LRSARQGHPSYRQIAQLMFREISAVHPFLAAGMRFVDHNEYDLERLAAEQRIDQKRQQVGR
>Mature_541_residues
METQQPETFTEQEIELLQPFVTNVDRPIFCLRNLPEVVKGALFARYSRSSKSLRRLLLDEFINEPESGFSAMVSAQDHNP
AAQLIATRQAEAFYDRVLIGYGDDSVAELGGAHLACEGVSNIAAKLLEDSRLGISPLEKSTRYVRFDRKGPDGYPYLREP
AIMASPLADRYVAVMDHLFTTYSELLEPVQAWLQQQYPRDEATTPRAYRNTIQAKALDLLRGLLPMATQTNVGLFGNGRA
FEYLIIKLAASPFAEAQALSKMIQAELDQVIPSFVKRARSDRGQAYADYLATTREQVAALAHQIPVEADSTTPVTVTLVD
YDPRAEWKLAAAILYPHLDLPLPAIEELVAAMPEAERHALINAAVGDRANRFHRPGRAFEEPYYTFDILADIGAYRDLQR
HRVLTQERQRFTVRHGYVTPPELEEIGVADRYRTALEQAADLVTALEATLPNEAQYAVPLAFRVRWRIKLNLREAYHLIE
LRSARQGHPSYRQIAQLMFREISAVHPFLAAGMRFVDHNEYDLERLAAEQRIDQKRQQVGR

Specific function: Unknown

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 thyX (flavin-dependent thymidylate synthase) domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: NA

Molecular weight: Translated: 61248; Mature: 61248

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METQQPETFTEQEIELLQPFVTNVDRPIFCLRNLPEVVKGALFARYSRSSKSLRRLLLDE
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FINEPESGFSAMVSAQDHNPAAQLIATRQAEAFYDRVLIGYGDDSVAELGGAHLACEGVS
HHCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCEEEECCCCHHHHHCCCCEEHHHHH
NIAAKLLEDSRLGISPLEKSTRYVRFDRKGPDGYPYLREPAIMASPLADRYVAVMDHLFT
HHHHHHHHCCCCCCCHHHHCCCEEEEECCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHH
TYSELLEPVQAWLQQQYPRDEATTPRAYRNTIQAKALDLLRGLLPMATQTNVGLFGNGRA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
FEYLIIKLAASPFAEAQALSKMIQAELDQVIPSFVKRARSDRGQAYADYLATTREQVAAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AHQIPVEADSTTPVTVTLVDYDPRAEWKLAAAILYPHLDLPLPAIEELVAAMPEAERHAL
HHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHH
INAAVGDRANRFHRPGRAFEEPYYTFDILADIGAYRDLQRHRVLTQERQRFTVRHGYVTP
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PELEEIGVADRYRTALEQAADLVTALEATLPNEAQYAVPLAFRVRWRIKLNLREAYHLIE
CCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEEEHHHHHHHHH
LRSARQGHPSYRQIAQLMFREISAVHPFLAAGMRFVDHNEYDLERLAAEQRIDQKRQQVG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHC
R
C
>Mature Secondary Structure
METQQPETFTEQEIELLQPFVTNVDRPIFCLRNLPEVVKGALFARYSRSSKSLRRLLLDE
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FINEPESGFSAMVSAQDHNPAAQLIATRQAEAFYDRVLIGYGDDSVAELGGAHLACEGVS
HHCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCEEEECCCCHHHHHCCCCEEHHHHH
NIAAKLLEDSRLGISPLEKSTRYVRFDRKGPDGYPYLREPAIMASPLADRYVAVMDHLFT
HHHHHHHHCCCCCCCHHHHCCCEEEEECCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHH
TYSELLEPVQAWLQQQYPRDEATTPRAYRNTIQAKALDLLRGLLPMATQTNVGLFGNGRA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
FEYLIIKLAASPFAEAQALSKMIQAELDQVIPSFVKRARSDRGQAYADYLATTREQVAAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AHQIPVEADSTTPVTVTLVDYDPRAEWKLAAAILYPHLDLPLPAIEELVAAMPEAERHAL
HHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHH
INAAVGDRANRFHRPGRAFEEPYYTFDILADIGAYRDLQRHRVLTQERQRFTVRHGYVTP
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PELEEIGVADRYRTALEQAADLVTALEATLPNEAQYAVPLAFRVRWRIKLNLREAYHLIE
CCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEEEHHHHHHHHH
LRSARQGHPSYRQIAQLMFREISAVHPFLAAGMRFVDHNEYDLERLAAEQRIDQKRQQVG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]