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The map label for this gene is luxS

Identifier: 222152034

GI number: 222152034

Start: 1927706

End: 1928191

Strand: Direct

Name: luxS

Synonym: MCCL_1791

Alternate gene names: 222152034

Gene position: 1927706-1928191 (Clockwise)

Preceding gene: 222152033

Following gene: 222152036

Centisome position: 91.69

GC content: 37.45

Gene sequence:

>486_bases
ATGACTAAAAAAATGAACGTTGAAAGTTTCAACTTAGACCACACAATCGTAGATGCACCATTTGTACGATTAGCTGGTAT
CAAAGAAGGTATCAATGGTGATGTTATTCATAAATACGATATCCGTTTTAAACAACCGAATAAAGAACATATGGAGATGC
CTGCACTTCATTCTTTAGAACATCTGATGGCTGAAAACATCCGCAATCATACAGATAAAGTGGTAGACATCTCTCCTATG
GGATGTCAGACTGGCTTCTACGTTTCACTTATCAACCATGATAATTACGAAGACGTATTAGCGATATTAGAAAAGACTTT
AAATGACGTATTAGCAGCTGATGAAGTTCCTGCTTGTAATGAAGTTCAATGTGGATGGGCAGCGAGTCATTCTTTAGAAG
GTGCAAAAGCAATCGCACAGGAAATGTTATCTAAAAAAGACAGCTGGCATGTCATTTATCAGCCTGGAAAAGAACCACAA
GCTTAA

Upstream 100 bases:

>100_bases
CTGACGGTTTAGTTCGAATCTCTGTGGGTATTGAAGATAGTGAAGATTTAATCGCAGACTTAGAACAAGCATTTAAACAA
TTAAACTAGGAGTGACACTT

Downstream 100 bases:

>100_bases
TTCATAAACAAAGAAGTGTCGATTCTAAATATCGACACTTCTTTTTAAAATCTTATTAAATTTGTAGCTGCATATACATC
ATCATATTCATTTAAAACTT

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTKKMNVESFNLDHTIVDAPFVRLAGIKEGINGDVIHKYDIRFKQPNKEHMEMPALHSLEHLMAENIRNHTDKVVDISPM
GCQTGFYVSLINHDNYEDVLAILEKTLNDVLAADEVPACNEVQCGWAASHSLEGAKAIAQEMLSKKDSWHVIYQPGKEPQ
A

Sequences:

>Translated_161_residues
MTKKMNVESFNLDHTIVDAPFVRLAGIKEGINGDVIHKYDIRFKQPNKEHMEMPALHSLEHLMAENIRNHTDKVVDISPM
GCQTGFYVSLINHDNYEDVLAILEKTLNDVLAADEVPACNEVQCGWAASHSLEGAKAIAQEMLSKKDSWHVIYQPGKEPQ
A
>Mature_160_residues
TKKMNVESFNLDHTIVDAPFVRLAGIKEGINGDVIHKYDIRFKQPNKEHMEMPALHSLEHLMAENIRNHTDKVVDISPMG
CQTGFYVSLINHDNYEDVLAILEKTLNDVLAADEVPACNEVQCGWAASHSLEGAKAIAQEMLSKKDSWHVIYQPGKEPQA

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=146, Percent_Identity=41.0958904109589, Blast_Score=113, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_MACCJ (B9E8I0)

Other databases:

- EMBL:   AP009484
- RefSeq:   YP_002561194.1
- GeneID:   7390394
- GenomeReviews:   AP009484_GR
- KEGG:   mcl:MCCL_1791
- OMA:   VRIAKTM
- ProtClustDB:   PRK02260
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 18081; Mature: 17950

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKMNVESFNLDHTIVDAPFVRLAGIKEGINGDVIHKYDIRFKQPNKEHMEMPALHSLE
CCCCCCCCEECCCCEEECCCHHHHHHHHCCCCCCEEEEEECEECCCCHHHHCCCHHHHHH
HLMAENIRNHTDKVVDISPMGCQTGFYVSLINHDNYEDVLAILEKTLNDVLAADEVPACN
HHHHHHHHHHCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCC
EVQCGWAASHSLEGAKAIAQEMLSKKDSWHVIYQPGKEPQA
CCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
TKKMNVESFNLDHTIVDAPFVRLAGIKEGINGDVIHKYDIRFKQPNKEHMEMPALHSLE
CCCCCCCEECCCCEEECCCHHHHHHHHCCCCCCEEEEEECEECCCCHHHHCCCHHHHHH
HLMAENIRNHTDKVVDISPMGCQTGFYVSLINHDNYEDVLAILEKTLNDVLAADEVPACN
HHHHHHHHHHCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCC
EVQCGWAASHSLEGAKAIAQEMLSKKDSWHVIYQPGKEPQA
CCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA