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The map label for this gene is ktrB [H]

Identifier: 222151927

GI number: 222151927

Start: 1821309

End: 1822625

Strand: Direct

Name: ktrB [H]

Synonym: MCCL_1684

Alternate gene names: 222151927

Gene position: 1821309-1822625 (Clockwise)

Preceding gene: 222151924

Following gene: 222151933

Centisome position: 86.63

GC content: 40.09

Gene sequence:

>1317_bases
GTGAAAAAGAAAAAAAGTAATCCATATCTCGTGATTATCAGTTCGTTCTTCATCTTCTTAGCTATCGGCACAATGCTGTT
GGCACTTCCGATAGCACAAAGACAGCCAACATCATTTATCGACTGTCTGTTTATTGCAACCAGTGCATTTACAGTGACAG
GACTTGCAACGATAGATATTACAGCAAATTTCAATACATTTGGTCATATTATCATTATGATCCTTGTACAGGCTGGCGGA
CTCGGGATCATCACATTAGCGATGATCGTCTTTATCATGCTTGGTCGTAAGGTAGGACTAAAAAGCCGTTCATTAGCTAC
GGAAGCTTTGAACCAGCAAAACTTAGGCGGCATACTGCGTCTTGTTCTTAAACTGTTACTGATCAGTCTTTTATTCGAGT
CGATCGGTGCGGTATTGCTGGCTCTTGAATGGGTCCCATTGCTCGGGATTAAACGTGGATTATTCAATAGTTTCTTTACC
GCGGTAAGCGCATTTAACAATGCCGGTTTTGCACTGCACAGTGATAATCTCGTGCAGTATCAGACAAATCCTTTAACTAA
CTTTATTATCACTACATTAATCATTCTTGGAGGATTAGGATTTACTGTTATTCTTGATCTATACCAGAAAAAAAAGTTTA
GTCATCTTAGGCTGCATACGAAAATCATGATATTCGGCACAATCATTATTAATACGTTCGCGACACTGTCCATCTATTTA
CTTGAAATGAATAATCTTAAGACGCTCGGTGGCCATAATACGTTCGATCAGTTTCAGATGGCTTACTTCCAGGCTATTAC
GACAAGAACAGCAGGATTTAATACCATAGATATCGGTGCACTACAAACACCGACCATCTTGCTGATGATGCTATTTATGT
TTATCGGAGGCGGATCAACATCAACTGCCGGCGGGATTAAATTGACGACAGCTGTCGTTATCTTCTTCGGGACAATCAGT
TATATTAAACAACGTGAACAAATCAGTTTATTCAAAAGAGCCATCGATACTAAAAATCTTTTTAAAAGCTTCGCAATTGT
CGTATTGAGCTCCACCTTTATATTTATCATCACTTTGGCGCTTGTTATCGCAGAGCCGGATCTGCCATTTCTTGCAGTAA
TGTTCGAAGTCATATCAGCATTCGGCACAGTCGGATTGACGATGGGCATCACAGCGAAACTCTCTGTTATCGGAAAGTTG
CTCATTATTCTAATGATGATGATTGGTAAGATTGGTGTATTAACCATCGTGCTGACATTCTCTAAACCACAGAAAGCGCT
CTATACGTATCCGAAAGAAGATGTACTGACGGGGTAG

Upstream 100 bases:

>100_bases
TTATACCTAATTTTTTACAACAAATAAAGATAGATGTATATTGTAATTTATATCTTTATCATGTAATCTATTGCTATCAA
ATATTAAAGAAGGTTTCTAA

Downstream 100 bases:

>100_bases
ATAATATTATAAATTTGCATCAAAAAAGAGAAGAACTTCAAAATTCTTCTCTTTTTTAACATTAAAAATTAATCTTCAAT
ATTTTTCTTAATTCTTATTA

Product: K+ transporter integral membrane subunit

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: K(+)-uptake protein ktrB [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MKKKKSNPYLVIISSFFIFLAIGTMLLALPIAQRQPTSFIDCLFIATSAFTVTGLATIDITANFNTFGHIIIMILVQAGG
LGIITLAMIVFIMLGRKVGLKSRSLATEALNQQNLGGILRLVLKLLLISLLFESIGAVLLALEWVPLLGIKRGLFNSFFT
AVSAFNNAGFALHSDNLVQYQTNPLTNFIITTLIILGGLGFTVILDLYQKKKFSHLRLHTKIMIFGTIIINTFATLSIYL
LEMNNLKTLGGHNTFDQFQMAYFQAITTRTAGFNTIDIGALQTPTILLMMLFMFIGGGSTSTAGGIKLTTAVVIFFGTIS
YIKQREQISLFKRAIDTKNLFKSFAIVVLSSTFIFIITLALVIAEPDLPFLAVMFEVISAFGTVGLTMGITAKLSVIGKL
LIILMMMIGKIGVLTIVLTFSKPQKALYTYPKEDVLTG

Sequences:

>Translated_438_residues
MKKKKSNPYLVIISSFFIFLAIGTMLLALPIAQRQPTSFIDCLFIATSAFTVTGLATIDITANFNTFGHIIIMILVQAGG
LGIITLAMIVFIMLGRKVGLKSRSLATEALNQQNLGGILRLVLKLLLISLLFESIGAVLLALEWVPLLGIKRGLFNSFFT
AVSAFNNAGFALHSDNLVQYQTNPLTNFIITTLIILGGLGFTVILDLYQKKKFSHLRLHTKIMIFGTIIINTFATLSIYL
LEMNNLKTLGGHNTFDQFQMAYFQAITTRTAGFNTIDIGALQTPTILLMMLFMFIGGGSTSTAGGIKLTTAVVIFFGTIS
YIKQREQISLFKRAIDTKNLFKSFAIVVLSSTFIFIITLALVIAEPDLPFLAVMFEVISAFGTVGLTMGITAKLSVIGKL
LIILMMMIGKIGVLTIVLTFSKPQKALYTYPKEDVLTG
>Mature_438_residues
MKKKKSNPYLVIISSFFIFLAIGTMLLALPIAQRQPTSFIDCLFIATSAFTVTGLATIDITANFNTFGHIIIMILVQAGG
LGIITLAMIVFIMLGRKVGLKSRSLATEALNQQNLGGILRLVLKLLLISLLFESIGAVLLALEWVPLLGIKRGLFNSFFT
AVSAFNNAGFALHSDNLVQYQTNPLTNFIITTLIILGGLGFTVILDLYQKKKFSHLRLHTKIMIFGTIIINTFATLSIYL
LEMNNLKTLGGHNTFDQFQMAYFQAITTRTAGFNTIDIGALQTPTILLMMLFMFIGGGSTSTAGGIKLTTAVVIFFGTIS
YIKQREQISLFKRAIDTKNLFKSFAIVVLSSTFIFIITLALVIAEPDLPFLAVMFEVISAFGTVGLTMGITAKLSVIGKL
LIILMMMIGKIGVLTIVLTFSKPQKALYTYPKEDVLTG

Specific function: Integral membrane subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family. Ktr (TC 2.A.38.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787626, Length=437, Percent_Identity=24.9427917620137, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 47909; Mature: 47909

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKKSNPYLVIISSFFIFLAIGTMLLALPIAQRQPTSFIDCLFIATSAFTVTGLATIDI
CCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEEEEEEE
TANFNTFGHIIIMILVQAGGLGIITLAMIVFIMLGRKVGLKSRSLATEALNQQNLGGILR
EECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHH
LVLKLLLISLLFESIGAVLLALEWVPLLGIKRGLFNSFFTAVSAFNNAGFALHSDNLVQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEE
QTNPLTNFIITTLIILGGLGFTVILDLYQKKKFSHLRLHTKIMIFGTIIINTFATLSIYL
ECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
LEMNNLKTLGGHNTFDQFQMAYFQAITTRTAGFNTIDIGALQTPTILLMMLFMFIGGGST
EEECCEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCCCC
STAGGIKLTTAVVIFFGTISYIKQREQISLFKRAIDTKNLFKSFAIVVLSSTFIFIITLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVIAEPDLPFLAVMFEVISAFGTVGLTMGITAKLSVIGKLLIILMMMIGKIGVLTIVLTF
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEC
SKPQKALYTYPKEDVLTG
CCCCHHHHCCCCHHCCCC
>Mature Secondary Structure
MKKKKSNPYLVIISSFFIFLAIGTMLLALPIAQRQPTSFIDCLFIATSAFTVTGLATIDI
CCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEEEEEEE
TANFNTFGHIIIMILVQAGGLGIITLAMIVFIMLGRKVGLKSRSLATEALNQQNLGGILR
EECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHH
LVLKLLLISLLFESIGAVLLALEWVPLLGIKRGLFNSFFTAVSAFNNAGFALHSDNLVQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEE
QTNPLTNFIITTLIILGGLGFTVILDLYQKKKFSHLRLHTKIMIFGTIIINTFATLSIYL
ECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
LEMNNLKTLGGHNTFDQFQMAYFQAITTRTAGFNTIDIGALQTPTILLMMLFMFIGGGST
EEECCEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCCCC
STAGGIKLTTAVVIFFGTISYIKQREQISLFKRAIDTKNLFKSFAIVVLSSTFIFIITLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVIAEPDLPFLAVMFEVISAFGTVGLTMGITAKLSVIGKLLIILMMMIGKIGVLTIVLTF
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEC
SKPQKALYTYPKEDVLTG
CCCCHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]