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The map label for this gene is namA [H]

Identifier: 222151913

GI number: 222151913

Start: 1807697

End: 1808737

Strand: Direct

Name: namA [H]

Synonym: MCCL_1670

Alternate gene names: 222151913

Gene position: 1807697-1808737 (Clockwise)

Preceding gene: 222151911

Following gene: 222151916

Centisome position: 85.99

GC content: 43.04

Gene sequence:

>1041_bases
ATGAACACAAAATTAAATACACATATAAAAATAAAAGATCTGACACTTAAAAATCGTATCGTTATGCCTCCGATGTGCCA
GTATTCTGTCGAAAAGAAAGATGGCACACCGACAGATTGGCACTATATACATTATGCTTCGCGTGCTGTTGGAGGCACAG
GACTGATTATTGTGGAAATGACAAATGTTGAACCCGACGGCAGAATTACCGATCACTGTCTTGGATTATGGGATGATGCT
CAAATTCCAGCTTATCAGCGTATCGTCCAGGGAATTCATGATAATGGTGCTAAAGCCGCAATTCAAATCGCACACGCAGG
ACGTAAAGCGACACATATAGAGACACCTGTCTCAAGCTCAGAAACACCGCTCGATGAACCGACAAAGTTCGGTCCAATAC
GTTATCCTCGCGCGCTTTCAACGGAAGAAGTAAAGGTTATGGTGGATAAGTATAAAGAAAGTGCGAGACGTGCGGTTGAA
GCCGGATTTGATGCGATTGAGGTTCACGGTGCACACGGATATCTCATTCATCAGTTTCACTCACCTTCGATCAACAAGCG
AACAGATGAATATGGTAAAGACTTATCTCTATTCGGCTGCGAAGTAATACAAGCGGTTAAGTCTGTTATGCCTGAAGGAA
TGCCGCTCATCTTCAGAATTTCTGCTCGTGAATATATGGATGGCGGTTATGACTTAGAACATGCACTGCATATTGCTGAA
GCTTATCAAGCAGCGGGTGTGGATGTTTTCCATATTTCAACTGGTGGAGAGGCACCTGCTGGCAAAGAGAAGCCAGGAAA
CTACCCAGGATATCAAGTGCCATTCGCACGTGCATTTAAAGAAAGATTCAACATACCTGTCATCGCAGTAGGCATGCTGG
ATAGTGCAGAAACTGCTGAAATGGTGCTGAACAATGATGATATCGATCTTGTTGCTATCGGACGTGGTATGCTAAATGAT
CCTTATTGGGCAATTCATGCAGTGAAATCTTTAAGAGATGATGTGGAAATTCCAAAACAATACGAACGTGGGATTCATTA
A

Upstream 100 bases:

>100_bases
TCACAAATGAAATTTTTACGACATCGAATATATTTAACAGTTCAAATATTCGAATTCTATATTTATTCAGTATAAAATAC
ACATATAAGGAGTGATTCAA

Downstream 100 bases:

>100_bases
TGTACGATTACTTACTCTTTAATCTGGATGGTGCTGGATAAAGCAGAAGTGATTGTGACAGTTATAGATACCTGTCAACT
AAATCCAGGTAAGACAAGGT

Product: NADH-dependent flavin oxidoreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MNTKLNTHIKIKDLTLKNRIVMPPMCQYSVEKKDGTPTDWHYIHYASRAVGGTGLIIVEMTNVEPDGRITDHCLGLWDDA
QIPAYQRIVQGIHDNGAKAAIQIAHAGRKATHIETPVSSSETPLDEPTKFGPIRYPRALSTEEVKVMVDKYKESARRAVE
AGFDAIEVHGAHGYLIHQFHSPSINKRTDEYGKDLSLFGCEVIQAVKSVMPEGMPLIFRISAREYMDGGYDLEHALHIAE
AYQAAGVDVFHISTGGEAPAGKEKPGNYPGYQVPFARAFKERFNIPVIAVGMLDSAETAEMVLNNDDIDLVAIGRGMLND
PYWAIHAVKSLRDDVEIPKQYERGIH

Sequences:

>Translated_346_residues
MNTKLNTHIKIKDLTLKNRIVMPPMCQYSVEKKDGTPTDWHYIHYASRAVGGTGLIIVEMTNVEPDGRITDHCLGLWDDA
QIPAYQRIVQGIHDNGAKAAIQIAHAGRKATHIETPVSSSETPLDEPTKFGPIRYPRALSTEEVKVMVDKYKESARRAVE
AGFDAIEVHGAHGYLIHQFHSPSINKRTDEYGKDLSLFGCEVIQAVKSVMPEGMPLIFRISAREYMDGGYDLEHALHIAE
AYQAAGVDVFHISTGGEAPAGKEKPGNYPGYQVPFARAFKERFNIPVIAVGMLDSAETAEMVLNNDDIDLVAIGRGMLND
PYWAIHAVKSLRDDVEIPKQYERGIH
>Mature_346_residues
MNTKLNTHIKIKDLTLKNRIVMPPMCQYSVEKKDGTPTDWHYIHYASRAVGGTGLIIVEMTNVEPDGRITDHCLGLWDDA
QIPAYQRIVQGIHDNGAKAAIQIAHAGRKATHIETPVSSSETPLDEPTKFGPIRYPRALSTEEVKVMVDKYKESARRAVE
AGFDAIEVHGAHGYLIHQFHSPSINKRTDEYGKDLSLFGCEVIQAVKSVMPEGMPLIFRISAREYMDGGYDLEHALHIAE
AYQAAGVDVFHISTGGEAPAGKEKPGNYPGYQVPFARAFKERFNIPVIAVGMLDSAETAEMVLNNDDIDLVAIGRGMLND
PYWAIHAVKSLRDDVEIPKQYERGIH

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=348, Percent_Identity=32.183908045977, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789463, Length=312, Percent_Identity=29.1666666666667, Blast_Score=126, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17564188, Length=308, Percent_Identity=28.5714285714286, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17559802, Length=331, Percent_Identity=26.5861027190332, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17559804, Length=274, Percent_Identity=30.6569343065693, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI72001454, Length=308, Percent_Identity=29.5454545454545, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17565138, Length=234, Percent_Identity=29.4871794871795, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17540738, Length=267, Percent_Identity=30.7116104868914, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17566914, Length=262, Percent_Identity=25.9541984732824, Blast_Score=91, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6321973, Length=230, Percent_Identity=30.4347826086957, Blast_Score=106, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6325086, Length=232, Percent_Identity=28.8793103448276, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 38417; Mature: 38417

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKLNTHIKIKDLTLKNRIVMPPMCQYSVEKKDGTPTDWHYIHYASRAVGGTGLIIVEM
CCCCCCCEEEEEEEEECCEECCCCHHCCEEECCCCCCCCEEEEEEHHHCCCCCEEEEEEE
TNVEPDGRITDHCLGLWDDAQIPAYQRIVQGIHDNGAKAAIQIAHAGRKATHIETPVSSS
ECCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCEEECCCCCC
ETPLDEPTKFGPIRYPRALSTEEVKVMVDKYKESARRAVEAGFDAIEVHGAHGYLIHQFH
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEC
SPSINKRTDEYGKDLSLFGCEVIQAVKSVMPEGMPLIFRISAREYMDGGYDLEHALHIAE
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCCCCHHHHHHHHH
AYQAAGVDVFHISTGGEAPAGKEKPGNYPGYQVPFARAFKERFNIPVIAVGMLDSAETAE
HHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHH
MVLNNDDIDLVAIGRGMLNDPYWAIHAVKSLRDDVEIPKQYERGIH
HEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
>Mature Secondary Structure
MNTKLNTHIKIKDLTLKNRIVMPPMCQYSVEKKDGTPTDWHYIHYASRAVGGTGLIIVEM
CCCCCCCEEEEEEEEECCEECCCCHHCCEEECCCCCCCCEEEEEEHHHCCCCCEEEEEEE
TNVEPDGRITDHCLGLWDDAQIPAYQRIVQGIHDNGAKAAIQIAHAGRKATHIETPVSSS
ECCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCEEECCCCCC
ETPLDEPTKFGPIRYPRALSTEEVKVMVDKYKESARRAVEAGFDAIEVHGAHGYLIHQFH
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEC
SPSINKRTDEYGKDLSLFGCEVIQAVKSVMPEGMPLIFRISAREYMDGGYDLEHALHIAE
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCCCCHHHHHHHHH
AYQAAGVDVFHISTGGEAPAGKEKPGNYPGYQVPFARAFKERFNIPVIAVGMLDSAETAE
HHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHH
MVLNNDDIDLVAIGRGMLNDPYWAIHAVKSLRDDVEIPKQYERGIH
HEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]