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The map label for this gene is speH [H]

Identifier: 222151905

GI number: 222151905

Start: 1800279

End: 1800704

Strand: Direct

Name: speH [H]

Synonym: MCCL_1662

Alternate gene names: 222151905

Gene position: 1800279-1800704 (Clockwise)

Preceding gene: 222151904

Following gene: 222151906

Centisome position: 85.63

GC content: 38.26

Gene sequence:

>426_bases
ATGAAGTTAACGACACTTGGAAGACACGTTTTAATCGAATACTATAACTGTGACAAAGATATTTTAAAGGACCATGATAA
AGTAGAAGCAATCATGAATGAAGCTGCCCGCGTAAGTGGTGCGACAATCGTTGAGAGCTGTTTCCATACATTCAATCCGT
ACGGTGTAAGTGGTGCTGTTATCATCTCAGAGTCACATTTAACAATTCATACATGGCCTGAATATGGCTATGCATCAGTT
GATGTATTTACTTGTGGAGATACAGTTGACCCTTGGCGTGCTGAAGATTATCTCCAAAAAGCATTGAAAGCTGAACTTTC
AGATTCATATGAAATCGGTCGTGGTATGGCTGATAAAATTCACAAATATTCTAATGGTGAAATCGTCGTAGAATCATTCA
AACCTGTGGAAGTAGCAGCTAAATAA

Upstream 100 bases:

>100_bases
TCGACTACTGGAAATTTATTAACGACCAGCCCATCATCAAGATTGGCGCAGAAAACAAAAATGAAGTATTTATAATTGAT
CATAAGGGAGATATTTAATA

Downstream 100 bases:

>100_bases
GGAGGAATTATACATGTTAGATTTATGGTATACAGAGAATCACACGGACAACGTAAAATTTTCTATTAAAACAACAGAAC
ATCTATTAACCGAAAAAACA

Product: S-adenosylmethionine decarboxylase

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MKLTTLGRHVLIEYYNCDKDILKDHDKVEAIMNEAARVSGATIVESCFHTFNPYGVSGAVIISESHLTIHTWPEYGYASV
DVFTCGDTVDPWRAEDYLQKALKAELSDSYEIGRGMADKIHKYSNGEIVVESFKPVEVAAK

Sequences:

>Translated_141_residues
MKLTTLGRHVLIEYYNCDKDILKDHDKVEAIMNEAARVSGATIVESCFHTFNPYGVSGAVIISESHLTIHTWPEYGYASV
DVFTCGDTVDPWRAEDYLQKALKAELSDSYEIGRGMADKIHKYSNGEIVVESFKPVEVAAK
>Mature_141_residues
MKLTTLGRHVLIEYYNCDKDILKDHDKVEAIMNEAARVSGATIVESCFHTFNPYGVSGAVIISESHLTIHTWPEYGYASV
DVFTCGDTVDPWRAEDYLQKALKAELSDSYEIGRGMADKIHKYSNGEIVVESFKPVEVAAK

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 15762; Mature: 15762

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTTLGRHVLIEYYNCDKDILKDHDKVEAIMNEAARVSGATIVESCFHTFNPYGVSGAV
CCCCCCCCEEEEEEECCCHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEE
IISESHLTIHTWPEYGYASVDVFTCGDTVDPWRAEDYLQKALKAELSDSYEIGRGMADKI
EEECCCEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCHHHHH
HKYSNGEIVVESFKPVEVAAK
HCCCCCCEEEECCCCEEEECC
>Mature Secondary Structure
MKLTTLGRHVLIEYYNCDKDILKDHDKVEAIMNEAARVSGATIVESCFHTFNPYGVSGAV
CCCCCCCCEEEEEEECCCHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEE
IISESHLTIHTWPEYGYASVDVFTCGDTVDPWRAEDYLQKALKAELSDSYEIGRGMADKI
EEECCCEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCHHHHH
HKYSNGEIVVESFKPVEVAAK
HCCCCCCEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA