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The map label for this gene is ywbI [H]

Identifier: 222151705

GI number: 222151705

Start: 1578715

End: 1579602

Strand: Direct

Name: ywbI [H]

Synonym: MCCL_1458

Alternate gene names: 222151705

Gene position: 1578715-1579602 (Clockwise)

Preceding gene: 222151698

Following gene: 222151708

Centisome position: 75.09

GC content: 37.5

Gene sequence:

>888_bases
GTGAAAATTCTACATTTCGAATATTATATTGCTGTTGTTGAACATCAAAGCTTCACGAGAGCGAGTGCGTATCTGCATAT
TAGTCAGCCATCGTTAACGGCTGCAATCAAGAAGCTGGAAGCGGAAATAGGATACAAGCTATTGACCAGAAGCACGAAGG
AAATCAAGATTACGGAACGTGGTATACTGTTCTATCAATATGCAAAAGATATTGTACATAAATACCAGCAGACGGTTGAA
CAGATGTATGACTTAAATTACAGCAATACCCCTAAAATTAAAGTCGGTATATTAGAGTCTGCAAGCAAATGGGTAAGTGC
TGTTATCGCGCAGCATAAAGGACATTATACGGATCAGCATTATATGATCAGAGAAATATTGACGACAGATGCAATCACAC
AGGCCATCACCAATTATGATGTCCATATCGCATTATCAAACGAACAGCTTATCCATGATGATATTATTTCACTGCCGTTA
TATTCAGAAGACTATATACTCACTGCGCCTAAAGATACATTCAACAATAAAAGAAGTGTCAATTTAAGCGATCTGCCGCT
GATTCTGCCGAATGATTCTTTTCAAGTTCGTAAACATCTAAATGATTATTTCTTAAGACATAACATCAGACCGCATATCG
TCCTTGAGGTAGACCGTTTTGAGACAGCACTTAATTATGTACATGAGCGTGTCGGTTATGCAGTCATCCCTAAAATATAC
TATCAGTCTCATAATGCATCTCATCTTAATGCGATTACGATTCGTCCGAACATCAGTCGCACAATCTATATCAATTACCA
TAAAAAAAGAAAGCACTCCACGAGAGTACTTTCTTTAATAGACTGCTTTATAAAATACTGGGATTACGGTGCACTGCAAA
AAACATGA

Upstream 100 bases:

>100_bases
TTTATTGTACTCGTTACTTATTATAATCTGCTATTATATAGTTATCTAATATAAATAAACTAACTATTAATAGGATTTAA
CTATAAAAGGAGCAGGAACT

Downstream 100 bases:

>100_bases
TATGTCCGACAAGCTTCGCTGTACGGCCATCTATATCATATTCTGGATTCATCTCAGCAATACTTAGGTGACGCGTCTTG
CCGTATGAGAGTACTGCTCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MKILHFEYYIAVVEHQSFTRASAYLHISQPSLTAAIKKLEAEIGYKLLTRSTKEIKITERGILFYQYAKDIVHKYQQTVE
QMYDLNYSNTPKIKVGILESASKWVSAVIAQHKGHYTDQHYMIREILTTDAITQAITNYDVHIALSNEQLIHDDIISLPL
YSEDYILTAPKDTFNNKRSVNLSDLPLILPNDSFQVRKHLNDYFLRHNIRPHIVLEVDRFETALNYVHERVGYAVIPKIY
YQSHNASHLNAITIRPNISRTIYINYHKKRKHSTRVLSLIDCFIKYWDYGALQKT

Sequences:

>Translated_295_residues
MKILHFEYYIAVVEHQSFTRASAYLHISQPSLTAAIKKLEAEIGYKLLTRSTKEIKITERGILFYQYAKDIVHKYQQTVE
QMYDLNYSNTPKIKVGILESASKWVSAVIAQHKGHYTDQHYMIREILTTDAITQAITNYDVHIALSNEQLIHDDIISLPL
YSEDYILTAPKDTFNNKRSVNLSDLPLILPNDSFQVRKHLNDYFLRHNIRPHIVLEVDRFETALNYVHERVGYAVIPKIY
YQSHNASHLNAITIRPNISRTIYINYHKKRKHSTRVLSLIDCFIKYWDYGALQKT
>Mature_295_residues
MKILHFEYYIAVVEHQSFTRASAYLHISQPSLTAAIKKLEAEIGYKLLTRSTKEIKITERGILFYQYAKDIVHKYQQTVE
QMYDLNYSNTPKIKVGILESASKWVSAVIAQHKGHYTDQHYMIREILTTDAITQAITNYDVHIALSNEQLIHDDIISLPL
YSEDYILTAPKDTFNNKRSVNLSDLPLILPNDSFQVRKHLNDYFLRHNIRPHIVLEVDRFETALNYVHERVGYAVIPKIY
YQSHNASHLNAITIRPNISRTIYINYHKKRKHSTRVLSLIDCFIKYWDYGALQKT

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=275, Percent_Identity=21.8181818181818, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787879, Length=252, Percent_Identity=26.1904761904762, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=21.1382113821138, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790399, Length=284, Percent_Identity=22.5352112676056, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787806, Length=253, Percent_Identity=22.9249011857708, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788887, Length=282, Percent_Identity=23.0496453900709, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788748, Length=286, Percent_Identity=21.3286713286713, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789639, Length=106, Percent_Identity=33.0188679245283, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693105, Length=286, Percent_Identity=22.3776223776224, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788481, Length=290, Percent_Identity=22.4137931034483, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34544; Mature: 34544

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILHFEYYIAVVEHQSFTRASAYLHISQPSLTAAIKKLEAEIGYKLLTRSTKEIKITER
CEEEEEEEEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHCHHHHHCCCCEEEEEEC
GILFYQYAKDIVHKYQQTVEQMYDLNYSNTPKIKVGILESASKWVSAVIAQHKGHYTDQH
CEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCHH
YMIREILTTDAITQAITNYDVHIALSNEQLIHDDIISLPLYSEDYILTAPKDTFNNKRSV
HHHHHHHHHHHHHHHHCCCEEEEEECCCCEECHHHHCCCCCCCCEEEECCCHHCCCCCCC
NLSDLPLILPNDSFQVRKHLNDYFLRHNIRPHIVLEVDRFETALNYVHERVGYAVIPKIY
CCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCCEEECHHE
YQSHNASHLNAITIRPNISRTIYINYHKKRKHSTRVLSLIDCFIKYWDYGALQKT
ECCCCCCCEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKILHFEYYIAVVEHQSFTRASAYLHISQPSLTAAIKKLEAEIGYKLLTRSTKEIKITER
CEEEEEEEEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHCHHHHHCCCCEEEEEEC
GILFYQYAKDIVHKYQQTVEQMYDLNYSNTPKIKVGILESASKWVSAVIAQHKGHYTDQH
CEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCHH
YMIREILTTDAITQAITNYDVHIALSNEQLIHDDIISLPLYSEDYILTAPKDTFNNKRSV
HHHHHHHHHHHHHHHHCCCEEEEEECCCCEECHHHHCCCCCCCCEEEECCCHHCCCCCCC
NLSDLPLILPNDSFQVRKHLNDYFLRHNIRPHIVLEVDRFETALNYVHERVGYAVIPKIY
CCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCCEEECHHE
YQSHNASHLNAITIRPNISRTIYINYHKKRKHSTRVLSLIDCFIKYWDYGALQKT
ECCCCCCCEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]