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The map label for this gene is zwf [H]

Identifier: 222151401

GI number: 222151401

Start: 1260140

End: 1261648

Strand: Direct

Name: zwf [H]

Synonym: MCCL_1154

Alternate gene names: 222151401

Gene position: 1260140-1261648 (Clockwise)

Preceding gene: 222151399

Following gene: 222151402

Centisome position: 59.94

GC content: 38.63

Gene sequence:

>1509_bases
TTGGATATAAAAAAGCAAAACATTCCCTGCTTAATTACCATTTTTGGTGCGACAGGAGACTTAAGTCATCGTAAATTATT
TCCATCCCTGTTCCACCTTTTTCAACAGGGAAATCTCAATGACCAAATTGCAATCATAGGAATCGGTCGACGCGACTGGT
CAAACGATAAATTCAGAGCCGAAATCAGAGCATCTATCGAGAACTTCGTAGCTGATACGCATAAGATTGACGCCTTTATG
GAACACGTATTTTACCAGCCGCATGATGTAAATGATGCAGCAAGCTATGCATCGCTCAAATCTCTTTCAGAAACTTTGGA
TGCTGAATTTAATCTGCAAGGTAACCGTCTATTTTATTTAGCAATGGCTCCAGAATTCTTTGGTACCGTTACCGATCATT
TAAAATTAAGTGGCCTTACAAAGACGGATGGTTTCAAACGTTTAATCATTGAAAAACCATTCGGTAAGGATCTGAAATCT
GCTGAACAGTTGAATCAGCAGATTCGTAAATCATTCAAAGAAGAAGAAATATATCGTATCGATCACTATCTCGGAAAAGA
CATGGTACAAAACATTGAGGTTATTCGCTTTAGCAATGCTATGTTCGAACCATTATGGAACAATAAATACATCTCAAATA
TCCAGGTCACATCATCTGAAATCCTTGGTGTTGAAGACCGAGGTGGCTACTATGATAAGAGTGGTGCGCTTAAAGATATG
GTTCAGAATCATATGCTGCAAATCGTTTCTCTTCTGGCAATGGAGCCTCCTATCTCACTTTCATCAGAAGATATCAGAAA
TGAAAAAGTAAAGGCTTTACGTTCCATTCGCAAGATCAAACCAGAACATGTCAGAAGCTATTTTGTTCGCGGACAGTATG
ATGCTGGTGAAATCAATGGTGAGAAGGTAAAAAAATATCGTGATGAAGATAATGTGGCACCAGATAGTAACACCCCTACT
TTCGTTGCAGCGAAAGTCATGCTCGATAACTTTAGATGGGCTGGTGTGCCATTTTATATTAGAACCGGAAAGCGTATGAA
AGAAAAAGAAATCAGAGTGGTTGTAGAATTCAAAGAAATGCCGATGAATCTATATTATCAAAAAGATAAAGAACTCGATT
CAAATCTGCTGATCATCAATATTCAGCCAAATGAAGGCATTGAACTTCATTTAAATGCCCGTAAATATATAGAAGGTATC
GATACAGAGCCTGTAAAACTCTCTTATGCGATGACTACACAAGATAAGATGAATACCGTAGATGCATACGAAGGATTAAT
CTACGACTGTTTACGTGGCGATGCGACAAACTTTACGCATTGGGAAGAGTTGAAAGCAACCTGGTCGTATGTTGATACAG
TAGCGGAATACTGGGATAATAATCCAGCACCATTTCCAAACTACCCTGCAGGTCGAGCAACGGACCAATCAAGAGCGAAT
TACTGCTTAGTCGTGACAATTTCCATTGGTGGGACTTCTAAACATATAGACAGCTTTATCATTAAATAA

Upstream 100 bases:

>100_bases
AACCACCTTTTCATCACGTAATTATAGCATGTTTTAATTGTATTTTTATGTGTTCTATGAAAAAATATAAAGAATAATAA
TAGAATCGAGGTTAGTTATC

Downstream 100 bases:

>100_bases
CACCTGAACAGTTTTTGTTCGGGTGTTATTTAATACGGTTCAACTCTAAAATTCAAAGTAATAATTTTATTTTCTATTTA
TTTATGTTATCTTAATCATA

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: G6PD; Vegetative protein 11; VEG11 [H]

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MDIKKQNIPCLITIFGATGDLSHRKLFPSLFHLFQQGNLNDQIAIIGIGRRDWSNDKFRAEIRASIENFVADTHKIDAFM
EHVFYQPHDVNDAASYASLKSLSETLDAEFNLQGNRLFYLAMAPEFFGTVTDHLKLSGLTKTDGFKRLIIEKPFGKDLKS
AEQLNQQIRKSFKEEEIYRIDHYLGKDMVQNIEVIRFSNAMFEPLWNNKYISNIQVTSSEILGVEDRGGYYDKSGALKDM
VQNHMLQIVSLLAMEPPISLSSEDIRNEKVKALRSIRKIKPEHVRSYFVRGQYDAGEINGEKVKKYRDEDNVAPDSNTPT
FVAAKVMLDNFRWAGVPFYIRTGKRMKEKEIRVVVEFKEMPMNLYYQKDKELDSNLLIINIQPNEGIELHLNARKYIEGI
DTEPVKLSYAMTTQDKMNTVDAYEGLIYDCLRGDATNFTHWEELKATWSYVDTVAEYWDNNPAPFPNYPAGRATDQSRAN
YCLVVTISIGGTSKHIDSFIIK

Sequences:

>Translated_502_residues
MDIKKQNIPCLITIFGATGDLSHRKLFPSLFHLFQQGNLNDQIAIIGIGRRDWSNDKFRAEIRASIENFVADTHKIDAFM
EHVFYQPHDVNDAASYASLKSLSETLDAEFNLQGNRLFYLAMAPEFFGTVTDHLKLSGLTKTDGFKRLIIEKPFGKDLKS
AEQLNQQIRKSFKEEEIYRIDHYLGKDMVQNIEVIRFSNAMFEPLWNNKYISNIQVTSSEILGVEDRGGYYDKSGALKDM
VQNHMLQIVSLLAMEPPISLSSEDIRNEKVKALRSIRKIKPEHVRSYFVRGQYDAGEINGEKVKKYRDEDNVAPDSNTPT
FVAAKVMLDNFRWAGVPFYIRTGKRMKEKEIRVVVEFKEMPMNLYYQKDKELDSNLLIINIQPNEGIELHLNARKYIEGI
DTEPVKLSYAMTTQDKMNTVDAYEGLIYDCLRGDATNFTHWEELKATWSYVDTVAEYWDNNPAPFPNYPAGRATDQSRAN
YCLVVTISIGGTSKHIDSFIIK
>Mature_502_residues
MDIKKQNIPCLITIFGATGDLSHRKLFPSLFHLFQQGNLNDQIAIIGIGRRDWSNDKFRAEIRASIENFVADTHKIDAFM
EHVFYQPHDVNDAASYASLKSLSETLDAEFNLQGNRLFYLAMAPEFFGTVTDHLKLSGLTKTDGFKRLIIEKPFGKDLKS
AEQLNQQIRKSFKEEEIYRIDHYLGKDMVQNIEVIRFSNAMFEPLWNNKYISNIQVTSSEILGVEDRGGYYDKSGALKDM
VQNHMLQIVSLLAMEPPISLSSEDIRNEKVKALRSIRKIKPEHVRSYFVRGQYDAGEINGEKVKKYRDEDNVAPDSNTPT
FVAAKVMLDNFRWAGVPFYIRTGKRMKEKEIRVVVEFKEMPMNLYYQKDKELDSNLLIINIQPNEGIELHLNARKYIEGI
DTEPVKLSYAMTTQDKMNTVDAYEGLIYDCLRGDATNFTHWEELKATWSYVDTVAEYWDNNPAPFPNYPAGRATDQSRAN
YCLVVTISIGGTSKHIDSFIIK

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI108773793, Length=476, Percent_Identity=36.1344537815126, Blast_Score=299, Evalue=5e-81,
Organism=Homo sapiens, GI109389365, Length=476, Percent_Identity=36.1344537815126, Blast_Score=298, Evalue=6e-81,
Organism=Homo sapiens, GI52145310, Length=363, Percent_Identity=30.0275482093664, Blast_Score=155, Evalue=6e-38,
Organism=Escherichia coli, GI1788158, Length=483, Percent_Identity=39.7515527950311, Blast_Score=358, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17538218, Length=452, Percent_Identity=37.3893805309735, Blast_Score=308, Evalue=3e-84,
Organism=Saccharomyces cerevisiae, GI6324088, Length=469, Percent_Identity=36.4605543710021, Blast_Score=291, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24643350, Length=444, Percent_Identity=33.7837837837838, Blast_Score=261, Evalue=6e-70,
Organism=Drosophila melanogaster, GI24643352, Length=444, Percent_Identity=33.7837837837838, Blast_Score=261, Evalue=7e-70,
Organism=Drosophila melanogaster, GI221513548, Length=459, Percent_Identity=25.9259259259259, Blast_Score=186, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 57690; Mature: 57690

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKKQNIPCLITIFGATGDLSHRKLFPSLFHLFQQGNLNDQIAIIGIGRRDWSNDKFRA
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHH
EIRASIENFVADTHKIDAFMEHVFYQPHDVNDAASYASLKSLSETLDAEFNLQGNRLFYL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCEEEEE
AMAPEFFGTVTDHLKLSGLTKTDGFKRLIIEKPFGKDLKSAEQLNQQIRKSFKEEEIYRI
EECHHHHHHHHHHEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DHYLGKDMVQNIEVIRFSNAMFEPLWNNKYISNIQVTSSEILGVEDRGGYYDKSGALKDM
HHHHCHHHHCCEEEEEECCHHHCCCCCCCEECEEEEEHHHEEEECCCCCEECCCCHHHHH
VQNHMLQIVSLLAMEPPISLSSEDIRNEKVKALRSIRKIKPEHVRSYFVRGQYDAGEING
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCH
EKVKKYRDEDNVAPDSNTPTFVAAKVMLDNFRWAGVPFYIRTGKRMKEKEIRVVVEFKEM
HHHHHHCCCCCCCCCCCCCCCEEHEEHHCCCEECCCCEEEECCCCCCCCCEEEEEEEECC
PMNLYYQKDKELDSNLLIINIQPNEGIELHLNARKYIEGIDTEPVKLSYAMTTQDKMNTV
CCEEEEECCCCCCCCEEEEEECCCCCEEEEECHHHHHCCCCCCCEEEEEEEECCHHCCHH
DAYEGLIYDCLRGDATNFTHWEELKATWSYVDTVAEYWDNNPAPFPNYPAGRATDQSRAN
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
YCLVVTISIGGTSKHIDSFIIK
EEEEEEEEECCCHHHHHHHHCC
>Mature Secondary Structure
MDIKKQNIPCLITIFGATGDLSHRKLFPSLFHLFQQGNLNDQIAIIGIGRRDWSNDKFRA
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHH
EIRASIENFVADTHKIDAFMEHVFYQPHDVNDAASYASLKSLSETLDAEFNLQGNRLFYL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCEEEEE
AMAPEFFGTVTDHLKLSGLTKTDGFKRLIIEKPFGKDLKSAEQLNQQIRKSFKEEEIYRI
EECHHHHHHHHHHEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DHYLGKDMVQNIEVIRFSNAMFEPLWNNKYISNIQVTSSEILGVEDRGGYYDKSGALKDM
HHHHCHHHHCCEEEEEECCHHHCCCCCCCEECEEEEEHHHEEEECCCCCEECCCCHHHHH
VQNHMLQIVSLLAMEPPISLSSEDIRNEKVKALRSIRKIKPEHVRSYFVRGQYDAGEING
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCH
EKVKKYRDEDNVAPDSNTPTFVAAKVMLDNFRWAGVPFYIRTGKRMKEKEIRVVVEFKEM
HHHHHHCCCCCCCCCCCCCCCEEHEEHHCCCEECCCCEEEECCCCCCCCCEEEEEEEECC
PMNLYYQKDKELDSNLLIINIQPNEGIELHLNARKYIEGIDTEPVKLSYAMTTQDKMNTV
CCEEEEECCCCCCCCEEEEEECCCCCEEEEECHHHHHCCCCCCCEEEEEEEECCHHCCHH
DAYEGLIYDCLRGDATNFTHWEELKATWSYVDTVAEYWDNNPAPFPNYPAGRATDQSRAN
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
YCLVVTISIGGTSKHIDSFIIK
EEEEEEEEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9298659 [H]