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The map label for this gene is 222151129

Identifier: 222151129

GI number: 222151129

Start: 970036

End: 971037

Strand: Direct

Name: 222151129

Synonym: MCCL_0880

Alternate gene names: NA

Gene position: 970036-971037 (Clockwise)

Preceding gene: 222151128

Following gene: 222151130

Centisome position: 46.14

GC content: 37.33

Gene sequence:

>1002_bases
ATGAATAAAAAGTTACTGTTAAGTGCGAGTTGTGTCATTTTATTAGCAGGCTGTGGTGATCAGTCAGCTGATAAAGGTAA
GGAAGATAAGAAAGAAAAAGTGACGATAATGCTGGACTGGACGCCGAATACGAATCATACAGGCCTATATGTAGCACAAG
AGAAAGGTTACTTTGACAAACACGGTCTAGATGTGGAAATTAAGACACCTGGTGAAGTGAATGCGGATCAGCTCATTGCT
GCGAATAAAAAAGATGTTCAGTTCGGAATTAGTGCTCAGGAAACAGTGACCCAGTCTCGTTCAGAAGGTATTCCGGTTAA
ATCTATAGGAGCGATTATCCAGCATAATACGAGTGGATTTATGAGCTTGAAAGATAAAGCTATTAAATCACCGAAAGATT
ATGCAGGGAGAACATACGGTGGATGGGGTGCACCGATTGAACAGCCAATGATTGATGCAGTTATGAAAAAAGACGGAGCA
TCAGTGAAAGACACTAAAATTATCAATATGGGAAATACTGATTTCTTTACTGCATCTAAGAAGAACATCGATTTCGCATG
GGTTTATTACGGATGGACTGGAATCGAAGCAGAAACACGTAATATCGATGTTAATATGCAGTATTTAATTGATTATGATA
AGAATCTAGATTATTACACACCTGTCGTTATCGCGAATGAAAAGTATTTAAAATCTAATGGTGAGACAGCTAAGAAATTT
ATGACCGCACTTAAAGAAGGTTATGAATATTCAATTAAACATGACAAAGAGAGTGCAGATATTTTGATGAAGTCTGTTCC
GGAACTTAGAAAACAAGAAAAGCTCGTCTATGCATCACAAAAATATCTGTCACCTAAATATCAGGATGATGGGAAATACT
GGGGTTATCAGGAAGAGCGCATCTGGAAGAATTTTGGGCAGTTTATGAAAGATAACAAGGTGATTACTAAAGACTTCGTT
GCTAGAGATGCATTTACAAATGAATATGTGGAGGGTAAATAA

Upstream 100 bases:

>100_bases
TTCGTCCTAAACCCTTATATACCTGATCTGGGTTATACCAGCGTAGGGAAGTGCCAATTGACACAACCTGCAGTCAGGTT
GTGTTTTTTTGGAGGCTAAT

Downstream 100 bases:

>100_bases
TGGCAGATACAATAATGAGCATACAAATTATTCCGAAGACGCCAAATGGTGAAGATGTAATTCCATATGTTGATCGTGCA
ATTGAAGTGATTGAAGCATC

Product: pyrimidine precursor biosynthesis enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MNKKLLLSASCVILLAGCGDQSADKGKEDKKEKVTIMLDWTPNTNHTGLYVAQEKGYFDKHGLDVEIKTPGEVNADQLIA
ANKKDVQFGISAQETVTQSRSEGIPVKSIGAIIQHNTSGFMSLKDKAIKSPKDYAGRTYGGWGAPIEQPMIDAVMKKDGA
SVKDTKIINMGNTDFFTASKKNIDFAWVYYGWTGIEAETRNIDVNMQYLIDYDKNLDYYTPVVIANEKYLKSNGETAKKF
MTALKEGYEYSIKHDKESADILMKSVPELRKQEKLVYASQKYLSPKYQDDGKYWGYQEERIWKNFGQFMKDNKVITKDFV
ARDAFTNEYVEGK

Sequences:

>Translated_333_residues
MNKKLLLSASCVILLAGCGDQSADKGKEDKKEKVTIMLDWTPNTNHTGLYVAQEKGYFDKHGLDVEIKTPGEVNADQLIA
ANKKDVQFGISAQETVTQSRSEGIPVKSIGAIIQHNTSGFMSLKDKAIKSPKDYAGRTYGGWGAPIEQPMIDAVMKKDGA
SVKDTKIINMGNTDFFTASKKNIDFAWVYYGWTGIEAETRNIDVNMQYLIDYDKNLDYYTPVVIANEKYLKSNGETAKKF
MTALKEGYEYSIKHDKESADILMKSVPELRKQEKLVYASQKYLSPKYQDDGKYWGYQEERIWKNFGQFMKDNKVITKDFV
ARDAFTNEYVEGK
>Mature_333_residues
MNKKLLLSASCVILLAGCGDQSADKGKEDKKEKVTIMLDWTPNTNHTGLYVAQEKGYFDKHGLDVEIKTPGEVNADQLIA
ANKKDVQFGISAQETVTQSRSEGIPVKSIGAIIQHNTSGFMSLKDKAIKSPKDYAGRTYGGWGAPIEQPMIDAVMKKDGA
SVKDTKIINMGNTDFFTASKKNIDFAWVYYGWTGIEAETRNIDVNMQYLIDYDKNLDYYTPVVIANEKYLKSNGETAKKF
MTALKEGYEYSIKHDKESADILMKSVPELRKQEKLVYASQKYLSPKYQDDGKYWGYQEERIWKNFGQFMKDNKVITKDFV
ARDAFTNEYVEGK

Specific function: Probably involved in thiamine biosynthesis [H]

COG id: COG0715

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NMT1 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322616, Length=315, Percent_Identity=24.4444444444444, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319957, Length=315, Percent_Identity=24.4444444444444, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321050, Length=315, Percent_Identity=24.4444444444444, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323997, Length=315, Percent_Identity=25.3968253968254, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 37697; Mature: 37697

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKLLLSASCVILLAGCGDQSADKGKEDKKEKVTIMLDWTPNTNHTGLYVAQEKGYFDK
CCCEEEEECCEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCC
HGLDVEIKTPGEVNADQLIAANKKDVQFGISAQETVTQSRSEGIPVKSIGAIIQHNTSGF
CCCEEEEECCCCCCHHHEEECCCCCEEECCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
MSLKDKAIKSPKDYAGRTYGGWGAPIEQPMIDAVMKKDGASVKDTKIINMGNTDFFTASK
EEEHHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEECC
KNIDFAWVYYGWTGIEAETRNIDVNMQYLIDYDKNLDYYTPVVIANEKYLKSNGETAKKF
CCCCEEEEEEEEECCCEECCEEEEEEEEEEEECCCCCEECCEEEECCHHHHCCCHHHHHH
MTALKEGYEYSIKHDKESADILMKSVPELRKQEKLVYASQKYLSPKYQDDGKYWGYQEER
HHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
IWKNFGQFMKDNKVITKDFVARDAFTNEYVEGK
HHHHHHHHHHCCCEEHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNKKLLLSASCVILLAGCGDQSADKGKEDKKEKVTIMLDWTPNTNHTGLYVAQEKGYFDK
CCCEEEEECCEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCC
HGLDVEIKTPGEVNADQLIAANKKDVQFGISAQETVTQSRSEGIPVKSIGAIIQHNTSGF
CCCEEEEECCCCCCHHHEEECCCCCEEECCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
MSLKDKAIKSPKDYAGRTYGGWGAPIEQPMIDAVMKKDGASVKDTKIINMGNTDFFTASK
EEEHHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEECC
KNIDFAWVYYGWTGIEAETRNIDVNMQYLIDYDKNLDYYTPVVIANEKYLKSNGETAKKF
CCCCEEEEEEEEECCCEECCEEEEEEEEEEEECCCCCEECCEEEECCHHHHCCCHHHHHH
MTALKEGYEYSIKHDKESADILMKSVPELRKQEKLVYASQKYLSPKYQDDGKYWGYQEER
HHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
IWKNFGQFMKDNKVITKDFVARDAFTNEYVEGK
HHHHHHHHHHCCCEEHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]