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The map label for this gene is pgsA [H]

Identifier: 222151123

GI number: 222151123

Start: 962183

End: 962764

Strand: Direct

Name: pgsA [H]

Synonym: MCCL_0874

Alternate gene names: 222151123

Gene position: 962183-962764 (Clockwise)

Preceding gene: 222151122

Following gene: 222151124

Centisome position: 45.77

GC content: 37.29

Gene sequence:

>582_bases
ATGAATATACCAAATCAAATTACAGTAGCAAGGGTACTTTTAATACCGATATTTCTAGTATTCTTACTTTCAGATTTCAA
TATGGGTGATATTTCTGTGCTCGGGTCTGAAGTGATGCGCATCGAACAGTTTATTGCAGCATTAATTTTTATTTTTGCTT
CGCTGACGGACTGGATAGATGGCTATTTGGCGCGCAAATGGCAGCTCGTAACGAATATGGGGAAATTTCTAGATCCATTA
GCAGATAAATTACTTGTTTCAAGTGGTCTGATAGCATTAGTCGAGCTTGATGCAATATCTTCATGGGTGGCAATTGTAAT
TATTGCACGTGAATTTGCAGTTACAGGGCTTCGTCTTTTACAGATTGAACAAGGATTCGTGTCTGCAGCAGGACAATTAG
GAAAGATCAAAACGGCTGTAACTATGCTTGCGATGACATTACTTTTGCTTAATGAACCATTTTCAGAGTGGACAGGTCTT
AACAGTGGTTATCTTCTGATGTATGTAGCAGTATTCTTCACTGTATTATCTGGAATTGAATATTTTTATCACGGACGCGA
TGTATTTAAAAATTCAAAGTAG

Upstream 100 bases:

>100_bases
ATCAATAACCAGAAAGTTTCGGTTCCAAAGGAAGCGGAGAATCTTATCACACGAACTTATTTCTTCAAAGTTTCAAAAAA
TTAGAGTTAGGATGAATAAA

Downstream 100 bases:

>100_bases
CATAAAAAACATTTAGTATATTAGAAATACTAAATGTTTTTTATTGCAATAATTAAATTTTAGACGTGTTATTTTTCAGT
TTTCTCAAGTATCACCGTAA

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MNIPNQITVARVLLIPIFLVFLLSDFNMGDISVLGSEVMRIEQFIAALIFIFASLTDWIDGYLARKWQLVTNMGKFLDPL
ADKLLVSSGLIALVELDAISSWVAIVIIAREFAVTGLRLLQIEQGFVSAAGQLGKIKTAVTMLAMTLLLLNEPFSEWTGL
NSGYLLMYVAVFFTVLSGIEYFYHGRDVFKNSK

Sequences:

>Translated_193_residues
MNIPNQITVARVLLIPIFLVFLLSDFNMGDISVLGSEVMRIEQFIAALIFIFASLTDWIDGYLARKWQLVTNMGKFLDPL
ADKLLVSSGLIALVELDAISSWVAIVIIAREFAVTGLRLLQIEQGFVSAAGQLGKIKTAVTMLAMTLLLLNEPFSEWTGL
NSGYLLMYVAVFFTVLSGIEYFYHGRDVFKNSK
>Mature_193_residues
MNIPNQITVARVLLIPIFLVFLLSDFNMGDISVLGSEVMRIEQFIAALIFIFASLTDWIDGYLARKWQLVTNMGKFLDPL
ADKLLVSSGLIALVELDAISSWVAIVIIAREFAVTGLRLLQIEQGFVSAAGQLGKIKTAVTMLAMTLLLLNEPFSEWTGL
NSGYLLMYVAVFFTVLSGIEYFYHGRDVFKNSK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=191, Percent_Identity=38.2198952879581, Blast_Score=100, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24650130, Length=113, Percent_Identity=35.3982300884956, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650126, Length=113, Percent_Identity=35.3982300884956, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650128, Length=113, Percent_Identity=35.3982300884956, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21477; Mature: 21477

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIPNQITVARVLLIPIFLVFLLSDFNMGDISVLGSEVMRIEQFIAALIFIFASLTDWID
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYLARKWQLVTNMGKFLDPLADKLLVSSGLIALVELDAISSWVAIVIIAREFAVTGLRLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIEQGFVSAAGQLGKIKTAVTMLAMTLLLLNEPFSEWTGLNSGYLLMYVAVFFTVLSGIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHH
YFYHGRDVFKNSK
HHHCCHHHHCCCC
>Mature Secondary Structure
MNIPNQITVARVLLIPIFLVFLLSDFNMGDISVLGSEVMRIEQFIAALIFIFASLTDWID
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYLARKWQLVTNMGKFLDPLADKLLVSSGLIALVELDAISSWVAIVIIAREFAVTGLRLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIEQGFVSAAGQLGKIKTAVTMLAMTLLLLNEPFSEWTGLNSGYLLMYVAVFFTVLSGIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHH
YFYHGRDVFKNSK
HHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA