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The map label for this gene is coaD

Identifier: 222150996

GI number: 222150996

Start: 804704

End: 805201

Strand: Direct

Name: coaD

Synonym: MCCL_0746

Alternate gene names: 222150996

Gene position: 804704-805201 (Clockwise)

Preceding gene: 222150995

Following gene: 222150998

Centisome position: 38.28

GC content: 37.95

Gene sequence:

>498_bases
ATGAAGAATATAGCAGTTATACCTGGCAGTTTCGATCCGATTACTTTAGGTCATCTTGATATCATCAAGCGCAGTGCGGG
TCTATTTGATGTAGTTCATGTATCAGTGCTGAACAATGCAAGTAAACAAGGGTTCTTTACGATTGAAGAACGTATCGAAA
TGATTAGTGAAGCGGTTAAAGATATTCCGAATGTTGAAGTCGAGTATTTTCAAGGACTCCTTGTGGACTACTGTAACAAA
GTAGGTGCAAAACAGATAGTGCGTGGCCTACGTGCAGTCAGTGACTTTGAATATGAGATGCAGCTGACAAGTATGAATAA
GAAGCTTGATGATGACCTTGAAACATTATATATGATGACGAATAATCAGTATTCATTTATTTCATCGAGTATGACAAAAG
ATGTTGCAAAGTACGGTGGCGACGTTTCAAGTATCGTACCTCCGAATGTTGAACTTGCTTTAAAGCAAAAATATGCAGAA
ATAAACAGAAGGCCTTAA

Upstream 100 bases:

>100_bases
TAGAATGTGAAAAGCACGAAACAATCGATACGTTAGATTATGAAGTGCTGAAGCATGATAATTATGGCATTACAAAACTA
ATCTTATTAAGAGGGATAGA

Downstream 100 bases:

>100_bases
TTTAAGGTCTTCTGTAGATTACTGGATTATTGAATTCCGTCTGTGATTGATCCGTCAGTATGTTGTATACATCAGTAGCT
TTAACTTCCAGTGAGAAGTA

Product: phosphopantetheine adenyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MKNIAVIPGSFDPITLGHLDIIKRSAGLFDVVHVSVLNNASKQGFFTIEERIEMISEAVKDIPNVEVEYFQGLLVDYCNK
VGAKQIVRGLRAVSDFEYEMQLTSMNKKLDDDLETLYMMTNNQYSFISSSMTKDVAKYGGDVSSIVPPNVELALKQKYAE
INRRP

Sequences:

>Translated_165_residues
MKNIAVIPGSFDPITLGHLDIIKRSAGLFDVVHVSVLNNASKQGFFTIEERIEMISEAVKDIPNVEVEYFQGLLVDYCNK
VGAKQIVRGLRAVSDFEYEMQLTSMNKKLDDDLETLYMMTNNQYSFISSSMTKDVAKYGGDVSSIVPPNVELALKQKYAE
INRRP
>Mature_165_residues
MKNIAVIPGSFDPITLGHLDIIKRSAGLFDVVHVSVLNNASKQGFFTIEERIEMISEAVKDIPNVEVEYFQGLLVDYCNK
VGAKQIVRGLRAVSDFEYEMQLTSMNKKLDDDLETLYMMTNNQYSFISSSMTKDVAKYGGDVSSIVPPNVELALKQKYAE
INRRP

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=159, Percent_Identity=44.6540880503145, Blast_Score=155, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_MACCJ (B9EB42)

Other databases:

- EMBL:   AP009484
- RefSeq:   YP_002560149.1
- ProteinModelPortal:   B9EB42
- GeneID:   7389918
- GenomeReviews:   AP009484_GR
- KEGG:   mcl:MCCL_0746
- OMA:   VRQIAAM
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18561; Mature: 18561

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIAVIPGSFDPITLGHLDIIKRSAGLFDVVHVSVLNNASKQGFFTIEERIEMISEAVK
CCCEEECCCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHH
DIPNVEVEYFQGLLVDYCNKVGAKQIVRGLRAVSDFEYEMQLTSMNKKLDDDLETLYMMT
HCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
NNQYSFISSSMTKDVAKYGGDVSSIVPPNVELALKQKYAEINRRP
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKNIAVIPGSFDPITLGHLDIIKRSAGLFDVVHVSVLNNASKQGFFTIEERIEMISEAVK
CCCEEECCCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHH
DIPNVEVEYFQGLLVDYCNKVGAKQIVRGLRAVSDFEYEMQLTSMNKKLDDDLETLYMMT
HCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
NNQYSFISSSMTKDVAKYGGDVSSIVPPNVELALKQKYAEINRRP
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA