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The map label for this gene is purL

Identifier: 222150942

GI number: 222150942

Start: 743152

End: 745338

Strand: Direct

Name: purL

Synonym: MCCL_0692

Alternate gene names: 222150942

Gene position: 743152-745338 (Clockwise)

Preceding gene: 222150941

Following gene: 222150943

Centisome position: 35.35

GC content: 45.72

Gene sequence:

>2187_bases
ATGGTCAAGTTTCTAGAACCAACTGCAAATGAAATTAAAGAGAATAAATTATACCAGGATATGGGGCTTTCAGATAAAGA
GTACGACAAGGTGGTCGACATATTAGGACGTATGCCAAACTATACTGAAATTGGTATCTTCTCTGTAATGTGGAGTGAAC
ATTGTTCATACAAGCATTCTAAACCTTTCTTAAAGCAGTTCCCGACGACAGGTGAGCGTGTGTTGATGGGTCCTGGTGAA
GGCGCTGGTGTTGTGGATATCGGTGATAACCAGGCAGTAGTATTCAAGGTTGAGTCACATAACCACCCGTCTGCCATTGA
ACCTTATCAAGGTGCGGCGACAGGTGTCGGCGGTATCGTCCGTGATATCGTATCCATCGGTGCGCGTCCAATTCAGCTGC
TCAACAGCTTACGTTTCGGTGAATTAACAGAGAAGCAGAACCAGCGTCTATTCAAAGGGGTCGTTGCGGGTATCGGCGGC
TACGGTAACTGTATCGGTATCCCTACAGTTGCAGGTGAAATCGAGTTTGATCGTCAGTACGAAGGGAACCCCCTTGTCAA
TGCGATGTGCGTCGGTATTATCGACCATGACAAGATTCAAAAAGGAACAGCGAAAGGTGAAGGTAATCCTGTCATCTACG
TGGGACTTAAGACGGGACGTGACGGGATCCACGGTGCAACATTCGCATCTGAGGAGTTAAGTGAAGAAAGCGAATCTAAA
CGTCCATCAGTGCAGATCGGTGACCCATTTGTCGGTAAGAAGTTGATGGAAGCGACACTTAAAGCCATCACCTTCCCTGA
ATTAGTCGGAATCCAGGATATGGGTGCAGCAGGTCTGACATCATCAAGTTCTGAAATGGCGGCTAAAGGTGGCAGTGGTA
TTCATCTCGAACTCGAGAAAGTGCCGACGCGTGAAGCGGGTATTTCACCCTATGAGATGATGTTATCTGAAACACAGGAA
CGTATGCTGCTTGTTGTTGAAAAAGGAACGGAGCAGAAATTCTTAGATTTATTCGACCATTACGAATTAGATAGTGCTGT
AATCGGTCAAGTAACGGATACAGATCGTTTCGTATTGACGTATGAAGGGGAGGTCTTTGCAGATATTCCGGTACAGCCGT
TATCTGACGAAGCACCGGTATACATATTAGAAGGTCGTGCAGCACAGTTTGATGCTGTGAATCACGACTACTCAAATATC
GATGCACAGGATACTTTGATGAAGTTATTATCTCACCCGACAATGGCTTCTAAGAACTGGGCATATAGTCAATATGATCA
GCAGGTGGGTGCAAACACGATCATCAAGCCAGGACTATCAGCAGGTGTAACACGTGTTGAAGGTACGAAAAAAGCCATCG
CTGCAACACTTGACGGCGAAGCACGTTACGTATTCAACAACCCATACGAAGGTGGTAAGATGGTCGTTGCAGAAGCATAT
CGTAACTTAATATCTGTCGGCAGCTTACCTCTTGCAATGACGGACTGCTTAAACTACGGTAATCCTGAAAAGCCTGAAAT
CTATCAGCAGCTCGCAGATTCTACACGTGGTATGGCGGAAGCGTGTGGCGCACTGAACACACCTGTTGTTTCAGGTAACG
TCAGCCTATATAACGAAACAAAAGGTGATGCAATCTTCCCGACACCAGTAGTGGGTATGGTCGGATTGATTGAAGATGTT
GATTATTTAGTAGATTTTAAACCGTCTAAAGGCGATACAATCTATTTCGTCGGAGAGGTTAAACCGGACTTCGGTGGCAG
CCAGCTCGAGAAGCTATTATTCAATGAAGTCGCACATACTGATGTAGCGATCGACCTCGAACAGGAAGTAGCGCGCGGTG
AAGCGATTCGTCAGCACATCATTGACGGTAAGCTTGGTCATGTTCAAGCTGTCGGTAAAGGTGGGGTCGGCGTGAAACTC
GCACAGATTGCAGCATACTTCAATACAGGTCTTGAAGCGCAGCTTGATGTGAGTGATGCAGAACTGTTTGCTGAAACACA
AGGGAACTACATTGTTATTGCAAAACAAGGTAAAGAAATTGATATCGACGGTGCAGAAGCGATCGGTACATTCGGTACAG
AATCATTTAAACTATCTACAAACCAAGGGGAAGTTACTTTAGACGTGAATCGTATGACGGAGGCTTGGAAAGGGGCAATT
CACGCATGTATGACATCAGAGGTCTAA

Upstream 100 bases:

>100_bases
GTATGATGCCTCACCCGGAACGTGCGATGGAAGCATTGCTTGGTACGGATGACGGTGTGAAATTATTCGAATCCATTTTA
GAAAGCTGGGGGAAATAATC

Downstream 100 bases:

>100_bases
ACGAAGAGTGTGGCGTGTTCGGTATCTGGGGTCACCCAAATGCCGCGGAACTCACTTATATGGCGCTGCACTCATTGCAG
CACCGTGGTCAGGAAGGTGC

Product: phosphoribosylformylglycinamidine synthase II

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase II; FGAM synthase II

Number of amino acids: Translated: 728; Mature: 728

Protein sequence:

>728_residues
MVKFLEPTANEIKENKLYQDMGLSDKEYDKVVDILGRMPNYTEIGIFSVMWSEHCSYKHSKPFLKQFPTTGERVLMGPGE
GAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIVRDIVSIGARPIQLLNSLRFGELTEKQNQRLFKGVVAGIGG
YGNCIGIPTVAGEIEFDRQYEGNPLVNAMCVGIIDHDKIQKGTAKGEGNPVIYVGLKTGRDGIHGATFASEELSEESESK
RPSVQIGDPFVGKKLMEATLKAITFPELVGIQDMGAAGLTSSSSEMAAKGGSGIHLELEKVPTREAGISPYEMMLSETQE
RMLLVVEKGTEQKFLDLFDHYELDSAVIGQVTDTDRFVLTYEGEVFADIPVQPLSDEAPVYILEGRAAQFDAVNHDYSNI
DAQDTLMKLLSHPTMASKNWAYSQYDQQVGANTIIKPGLSAGVTRVEGTKKAIAATLDGEARYVFNNPYEGGKMVVAEAY
RNLISVGSLPLAMTDCLNYGNPEKPEIYQQLADSTRGMAEACGALNTPVVSGNVSLYNETKGDAIFPTPVVGMVGLIEDV
DYLVDFKPSKGDTIYFVGEVKPDFGGSQLEKLLFNEVAHTDVAIDLEQEVARGEAIRQHIIDGKLGHVQAVGKGGVGVKL
AQIAAYFNTGLEAQLDVSDAELFAETQGNYIVIAKQGKEIDIDGAEAIGTFGTESFKLSTNQGEVTLDVNRMTEAWKGAI
HACMTSEV

Sequences:

>Translated_728_residues
MVKFLEPTANEIKENKLYQDMGLSDKEYDKVVDILGRMPNYTEIGIFSVMWSEHCSYKHSKPFLKQFPTTGERVLMGPGE
GAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIVRDIVSIGARPIQLLNSLRFGELTEKQNQRLFKGVVAGIGG
YGNCIGIPTVAGEIEFDRQYEGNPLVNAMCVGIIDHDKIQKGTAKGEGNPVIYVGLKTGRDGIHGATFASEELSEESESK
RPSVQIGDPFVGKKLMEATLKAITFPELVGIQDMGAAGLTSSSSEMAAKGGSGIHLELEKVPTREAGISPYEMMLSETQE
RMLLVVEKGTEQKFLDLFDHYELDSAVIGQVTDTDRFVLTYEGEVFADIPVQPLSDEAPVYILEGRAAQFDAVNHDYSNI
DAQDTLMKLLSHPTMASKNWAYSQYDQQVGANTIIKPGLSAGVTRVEGTKKAIAATLDGEARYVFNNPYEGGKMVVAEAY
RNLISVGSLPLAMTDCLNYGNPEKPEIYQQLADSTRGMAEACGALNTPVVSGNVSLYNETKGDAIFPTPVVGMVGLIEDV
DYLVDFKPSKGDTIYFVGEVKPDFGGSQLEKLLFNEVAHTDVAIDLEQEVARGEAIRQHIIDGKLGHVQAVGKGGVGVKL
AQIAAYFNTGLEAQLDVSDAELFAETQGNYIVIAKQGKEIDIDGAEAIGTFGTESFKLSTNQGEVTLDVNRMTEAWKGAI
HACMTSEV
>Mature_728_residues
MVKFLEPTANEIKENKLYQDMGLSDKEYDKVVDILGRMPNYTEIGIFSVMWSEHCSYKHSKPFLKQFPTTGERVLMGPGE
GAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIVRDIVSIGARPIQLLNSLRFGELTEKQNQRLFKGVVAGIGG
YGNCIGIPTVAGEIEFDRQYEGNPLVNAMCVGIIDHDKIQKGTAKGEGNPVIYVGLKTGRDGIHGATFASEELSEESESK
RPSVQIGDPFVGKKLMEATLKAITFPELVGIQDMGAAGLTSSSSEMAAKGGSGIHLELEKVPTREAGISPYEMMLSETQE
RMLLVVEKGTEQKFLDLFDHYELDSAVIGQVTDTDRFVLTYEGEVFADIPVQPLSDEAPVYILEGRAAQFDAVNHDYSNI
DAQDTLMKLLSHPTMASKNWAYSQYDQQVGANTIIKPGLSAGVTRVEGTKKAIAATLDGEARYVFNNPYEGGKMVVAEAY
RNLISVGSLPLAMTDCLNYGNPEKPEIYQQLADSTRGMAEACGALNTPVVSGNVSLYNETKGDAIFPTPVVGMVGLIEDV
DYLVDFKPSKGDTIYFVGEVKPDFGGSQLEKLLFNEVAHTDVAIDLEQEVARGEAIRQHIIDGKLGHVQAVGKGGVGVKL
AQIAAYFNTGLEAQLDVSDAELFAETQGNYIVIAKQGKEIDIDGAEAIGTFGTESFKLSTNQGEVTLDVNRMTEAWKGAI
HACMTSEV

Specific function: Unknown

COG id: COG0046

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGAMS family

Homologues:

Organism=Escherichia coli, GI48994899, Length=776, Percent_Identity=24.0979381443299, Blast_Score=113, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURL_MACCJ (B9EAY8)

Other databases:

- EMBL:   AP009484
- RefSeq:   YP_002560095.1
- GeneID:   7389856
- GenomeReviews:   AP009484_GR
- KEGG:   mcl:MCCL_0692
- OMA:   ADYGNSI
- ProtClustDB:   PRK01213
- GO:   GO:0005737
- HAMAP:   MF_00420
- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR010074
- InterPro:   IPR016188
- TIGRFAMs:   TIGR01736

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C; SSF56042 AIR_synth_C; SSF55326 PurM_N-like

EC number: =6.3.5.3

Molecular weight: Translated: 78674; Mature: 78674

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKFLEPTANEIKENKLYQDMGLSDKEYDKVVDILGRMPNYTEIGIFSVMWSEHCSYKHS
CCEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
KPFLKQFPTTGERVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIV
CCHHHHCCCCCCEEEECCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHH
RDIVSIGARPIQLLNSLRFGELTEKQNQRLFKGVVAGIGGYGNCIGIPTVAGEIEFDRQY
HHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCEEECCEEECCCC
EGNPLVNAMCVGIIDHDKIQKGTAKGEGNPVIYVGLKTGRDGIHGATFASEELSEESESK
CCCCCEEEEEEEEECCCHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHC
RPSVQIGDPFVGKKLMEATLKAITFPELVGIQDMGAAGLTSSSSEMAAKGGSGIHLELEK
CCCEEECCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCHHHHCCCCCEEEEEEC
VPTREAGISPYEMMLSETQERMLLVVEKGTEQKFLDLFDHYELDSAVIGQVTDTDRFVLT
CCCCCCCCCHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCHHHCCEECCCCEEEEE
YEGEVFADIPVQPLSDEAPVYILEGRAAQFDAVNHDYSNIDAQDTLMKLLSHPTMASKNW
ECCCEEEECCCCCCCCCCCEEEEECCCCEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
AYSQYDQQVGANTIIKPGLSAGVTRVEGTKKAIAATLDGEARYVFNNPYEGGKMVVAEAY
CHHHHHHHCCCCCEECCCCHHCCEEECCCHHHEEEEECCCEEEEECCCCCCCEEEHHHHH
RNLISVGSLPLAMTDCLNYGNPEKPEIYQQLADSTRGMAEACGALNTPVVSGNVSLYNET
HHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCEEECCEEEEECC
KGDAIFPTPVVGMVGLIEDVDYLVDFKPSKGDTIYFVGEVKPDFGGSQLEKLLFNEVAHT
CCCEECCCHHHHHHHHHHHHHHHEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHC
DVAIDLEQEVARGEAIRQHIIDGKLGHVQAVGKGGVGVKLAQIAAYFNTGLEAQLDVSDA
CEEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEECCHH
ELFAETQGNYIVIAKQGKEIDIDGAEAIGTFGTESFKLSTNQGEVTLDVNRMTEAWKGAI
HHHHCCCCCEEEEECCCCEECCCCHHHHHCCCCCEEEEECCCCCEEEEHHHHHHHHHHHH
HACMTSEV
HHHHHCCC
>Mature Secondary Structure
MVKFLEPTANEIKENKLYQDMGLSDKEYDKVVDILGRMPNYTEIGIFSVMWSEHCSYKHS
CCEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
KPFLKQFPTTGERVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIV
CCHHHHCCCCCCEEEECCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHH
RDIVSIGARPIQLLNSLRFGELTEKQNQRLFKGVVAGIGGYGNCIGIPTVAGEIEFDRQY
HHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCEEECCEEECCCC
EGNPLVNAMCVGIIDHDKIQKGTAKGEGNPVIYVGLKTGRDGIHGATFASEELSEESESK
CCCCCEEEEEEEEECCCHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHC
RPSVQIGDPFVGKKLMEATLKAITFPELVGIQDMGAAGLTSSSSEMAAKGGSGIHLELEK
CCCEEECCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCHHHHCCCCCEEEEEEC
VPTREAGISPYEMMLSETQERMLLVVEKGTEQKFLDLFDHYELDSAVIGQVTDTDRFVLT
CCCCCCCCCHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCHHHCCEECCCCEEEEE
YEGEVFADIPVQPLSDEAPVYILEGRAAQFDAVNHDYSNIDAQDTLMKLLSHPTMASKNW
ECCCEEEECCCCCCCCCCCEEEEECCCCEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
AYSQYDQQVGANTIIKPGLSAGVTRVEGTKKAIAATLDGEARYVFNNPYEGGKMVVAEAY
CHHHHHHHCCCCCEECCCCHHCCEEECCCHHHEEEEECCCEEEEECCCCCCCEEEHHHHH
RNLISVGSLPLAMTDCLNYGNPEKPEIYQQLADSTRGMAEACGALNTPVVSGNVSLYNET
HHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCEEECCEEEEECC
KGDAIFPTPVVGMVGLIEDVDYLVDFKPSKGDTIYFVGEVKPDFGGSQLEKLLFNEVAHT
CCCEECCCHHHHHHHHHHHHHHHEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHC
DVAIDLEQEVARGEAIRQHIIDGKLGHVQAVGKGGVGVKLAQIAAYFNTGLEAQLDVSDA
CEEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEECCHH
ELFAETQGNYIVIAKQGKEIDIDGAEAIGTFGTESFKLSTNQGEVTLDVNRMTEAWKGAI
HHHHCCCCCEEEEECCCCEECCCCHHHHHCCCCCEEEEECCCCCEEEEHHHHHHHHHHHH
HACMTSEV
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA