Click here to switch to the map view.

The map label for this gene is purQ [H]

Identifier: 222150941

GI number: 222150941

Start: 742487

End: 743149

Strand: Direct

Name: purQ [H]

Synonym: MCCL_0691

Alternate gene names: 222150941

Gene position: 742487-743149 (Clockwise)

Preceding gene: 222150940

Following gene: 222150942

Centisome position: 35.32

GC content: 44.34

Gene sequence:

>663_bases
ATGAAGTTTGCTGTGATTGAATTTCCAGGTTCAAACTGCGATCGCGATATGTTCAATGCAGCTTTGAAGACTGGTTTTGA
AGCGGAATATGTTGATTATCGTAAGACGTCACTTGAAGGCTTTGACGGTGTGTTGATTCCAGGTGGATTCTCATTTGGTG
ACTACCTGCGCTGTGGTGCGATGGCACGTGTGGCACCGATTGTGCCGGAAGTAAGACGTTTAGCTGCTGAAGGTAAGCCA
GTGCTAGGTGTATGTAATGGATTCCAGATCCTGACGGAGATCGGATTATTACCAGGTGCTTTAATGCATAATACGAAGCA
TCAGTTTATCTGTCAGAACGAACCGCTTAAAATCGTCAATAACGACACGAAGTTTACACATAAGTACGATAAAGATGAGA
CAGTGATCTATCCGATTGCGCACGGGGAAGGTAATTACTACTGCTCAGATGAAACGTTAGCTGAACTGAAAGCAAACAAT
CAGATCATCTTAACGTATCATGACAATCCGAACGGCTCGATCGAAGATATCGCGGGAATCGTGAATAAAGCAGGCAACGT
ATGTGGTATGATGCCTCACCCGGAACGTGCGATGGAAGCATTGCTTGGTACGGATGACGGTGTGAAATTATTCGAATCCA
TTTTAGAAAGCTGGGGGAAATAA

Upstream 100 bases:

>100_bases
CCGTTGCAAACGTAGTCAATACATTAAGTGAGAAGTTATTTGCGAACACTGTAATCGAAGAATACAGCTACAAAATTGTT
GAAGATGAGGAGACGAAATA

Downstream 100 bases:

>100_bases
TCATGGTCAAGTTTCTAGAACCAACTGCAAATGAAATTAAAGAGAATAAATTATACCAGGATATGGGGCTTTCAGATAAA
GAGTACGACAAGGTGGTCGA

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MKFAVIEFPGSNCDRDMFNAALKTGFEAEYVDYRKTSLEGFDGVLIPGGFSFGDYLRCGAMARVAPIVPEVRRLAAEGKP
VLGVCNGFQILTEIGLLPGALMHNTKHQFICQNEPLKIVNNDTKFTHKYDKDETVIYPIAHGEGNYYCSDETLAELKANN
QIILTYHDNPNGSIEDIAGIVNKAGNVCGMMPHPERAMEALLGTDDGVKLFESILESWGK

Sequences:

>Translated_220_residues
MKFAVIEFPGSNCDRDMFNAALKTGFEAEYVDYRKTSLEGFDGVLIPGGFSFGDYLRCGAMARVAPIVPEVRRLAAEGKP
VLGVCNGFQILTEIGLLPGALMHNTKHQFICQNEPLKIVNNDTKFTHKYDKDETVIYPIAHGEGNYYCSDETLAELKANN
QIILTYHDNPNGSIEDIAGIVNKAGNVCGMMPHPERAMEALLGTDDGVKLFESILESWGK
>Mature_220_residues
MKFAVIEFPGSNCDRDMFNAALKTGFEAEYVDYRKTSLEGFDGVLIPGGFSFGDYLRCGAMARVAPIVPEVRRLAAEGKP
VLGVCNGFQILTEIGLLPGALMHNTKHQFICQNEPLKIVNNDTKFTHKYDKDETVIYPIAHGEGNYYCSDETLAELKANN
QIILTYHDNPNGSIEDIAGIVNKAGNVCGMMPHPERAMEALLGTDDGVKLFESILESWGK

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=246, Percent_Identity=28.8617886178862, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17553022, Length=235, Percent_Identity=28.5106382978723, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24582111, Length=231, Percent_Identity=30.7359307359307, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24582109, Length=231, Percent_Identity=30.7359307359307, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17137292, Length=231, Percent_Identity=30.7359307359307, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 24225; Mature: 24225

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAVIEFPGSNCDRDMFNAALKTGFEAEYVDYRKTSLEGFDGVLIPGGFSFGDYLRCGA
CCEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEECCCCCHHHHHHHCH
MARVAPIVPEVRRLAAEGKPVLGVCNGFQILTEIGLLPGALMHNTKHQFICQNEPLKIVN
HHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCHHHCCCCCCEEECCCCEEEEE
NDTKFTHKYDKDETVIYPIAHGEGNYYCSDETLAELKANNQIILTYHDNPNGSIEDIAGI
CCCEEEEECCCCCEEEEEEEECCCCEEECCHHHHHHCCCCEEEEEEECCCCCCHHHHHHH
VNKAGNVCGMMPHPERAMEALLGTDDGVKLFESILESWGK
HHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKFAVIEFPGSNCDRDMFNAALKTGFEAEYVDYRKTSLEGFDGVLIPGGFSFGDYLRCGA
CCEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEECCCCCHHHHHHHCH
MARVAPIVPEVRRLAAEGKPVLGVCNGFQILTEIGLLPGALMHNTKHQFICQNEPLKIVN
HHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCHHHCCCCCCEEECCCCEEEEE
NDTKFTHKYDKDETVIYPIAHGEGNYYCSDETLAELKANNQIILTYHDNPNGSIEDIAGI
CCCEEEEECCCCCEEEEEEEECCCCEEECCHHHHHHCCCCEEEEEEECCCCCCHHHHHHH
VNKAGNVCGMMPHPERAMEALLGTDDGVKLFESILESWGK
HHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA