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The map label for this gene is mecA

Identifier: 222150862

GI number: 222150862

Start: 656997

End: 657659

Strand: Direct

Name: mecA

Synonym: MCCL_0612

Alternate gene names: 222150862

Gene position: 656997-657659 (Clockwise)

Preceding gene: 222150861

Following gene: 222150863

Centisome position: 31.25

GC content: 35.75

Gene sequence:

>663_bases
ATGAGAATAGAGCGAGTGAATGAATCAACTTTAAAATTTTATTTGACATATACTGATATTGAAGCGCGTGGTTTCAAGCG
TGATGATCTGTGGACGAGCCGCAAGAAAGGTGAGGAATTCTTCTGGTCTGTGATGGAAGAGGTTAATCAGGAAGAGGATT
TCTTTTTCGATGGCCCTTTATGGATACAAGTCCATGCCTTTGATAAAGGAATTGAGGTTGTTGTAACAAAATCTAAGAAT
GATGATCTGCAGTTACCAGAAGATGACAGTGACTTAAATATAGATGAGAAAGTGAATGATTTTATTAATAATTCAATGCA
CAGCGATTCTGAACTACGCGATTTACTTATGCGTGCGTCAGAAGAATCGACAGAACAGTTCTTTATTGTACACTTTGACG
ATCTGGAAGATGTGATTCAGTTTAGTTATCATAATTATGAAGATGTAGACATTGAAGACTTATTGTATATGTATGAAGGT
AAATATTATTACTATGTAGAGTTCGATGACCATATGTCAGAAGATGCGATTCATAGTTATATTGCACATCTGCTGGAATA
TGCGAATGAGACACAAATTTCTCATGAACAGCTGGATGAATACGGTAAGATTGTGATGAGTCACAACGTAAAGCGTCAAG
TAAAGCAGTATTTTAAACAGTAA

Upstream 100 bases:

>100_bases
ATTTGCAGGTACCTCTATTTATAAACAGTTTTATTGTAGGAAATCTTTTCTTCGTGTACAATGATATTACCATTCATACA
TAGGATTGGAGGAATGACTC

Downstream 100 bases:

>100_bases
TCTTTACAAAATCTTATAGAATCAAAACAGCACTTTCTGATATATATTATCAGGAGGTGCTGTTTTTGATTCAGGCGATG
AATAGTAACGGAGAAATAGT

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MRIERVNESTLKFYLTYTDIEARGFKRDDLWTSRKKGEEFFWSVMEEVNQEEDFFFDGPLWIQVHAFDKGIEVVVTKSKN
DDLQLPEDDSDLNIDEKVNDFINNSMHSDSELRDLLMRASEESTEQFFIVHFDDLEDVIQFSYHNYEDVDIEDLLYMYEG
KYYYYVEFDDHMSEDAIHSYIAHLLEYANETQISHEQLDEYGKIVMSHNVKRQVKQYFKQ

Sequences:

>Translated_220_residues
MRIERVNESTLKFYLTYTDIEARGFKRDDLWTSRKKGEEFFWSVMEEVNQEEDFFFDGPLWIQVHAFDKGIEVVVTKSKN
DDLQLPEDDSDLNIDEKVNDFINNSMHSDSELRDLLMRASEESTEQFFIVHFDDLEDVIQFSYHNYEDVDIEDLLYMYEG
KYYYYVEFDDHMSEDAIHSYIAHLLEYANETQISHEQLDEYGKIVMSHNVKRQVKQYFKQ
>Mature_220_residues
MRIERVNESTLKFYLTYTDIEARGFKRDDLWTSRKKGEEFFWSVMEEVNQEEDFFFDGPLWIQVHAFDKGIEVVVTKSKN
DDLQLPEDDSDLNIDEKVNDFINNSMHSDSELRDLLMRASEESTEQFFIVHFDDLEDVIQFSYHNYEDVDIEDLLYMYEG
KYYYYVEFDDHMSEDAIHSYIAHLLEYANETQISHEQLDEYGKIVMSHNVKRQVKQYFKQ

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MECA_MACCJ (B9EAQ8)

Other databases:

- EMBL:   AP009484
- RefSeq:   YP_002560015.1
- GeneID:   7390229
- GenomeReviews:   AP009484_GR
- KEGG:   mcl:MCCL_0612
- OMA:   VNENTIR
- ProtClustDB:   PRK02315
- HAMAP:   MF_01124
- InterPro:   IPR008681
- PIRSF:   PIRSF029008

Pfam domain/function: PF05389 MecA

EC number: NA

Molecular weight: Translated: 26539; Mature: 26539

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIERVNESTLKFYLTYTDIEARGFKRDDLWTSRKKGEEFFWSVMEEVNQEEDFFFDGPL
CCCCCCCCCEEEEEEEEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCEEECCCE
WIQVHAFDKGIEVVVTKSKNDDLQLPEDDSDLNIDEKVNDFINNSMHSDSELRDLLMRAS
EEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCC
EESTEQFFIVHFDDLEDVIQFSYHNYEDVDIEDLLYMYEGKYYYYVEFDDHMSEDAIHSY
CCCCCEEEEEEECCHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCHHHHHHH
IAHLLEYANETQISHEQLDEYGKIVMSHNVKRQVKQYFKQ
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MRIERVNESTLKFYLTYTDIEARGFKRDDLWTSRKKGEEFFWSVMEEVNQEEDFFFDGPL
CCCCCCCCCEEEEEEEEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCEEECCCE
WIQVHAFDKGIEVVVTKSKNDDLQLPEDDSDLNIDEKVNDFINNSMHSDSELRDLLMRAS
EEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCC
EESTEQFFIVHFDDLEDVIQFSYHNYEDVDIEDLLYMYEGKYYYYVEFDDHMSEDAIHSY
CCCCCEEEEEEECCHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCHHHHHHH
IAHLLEYANETQISHEQLDEYGKIVMSHNVKRQVKQYFKQ
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA