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The map label for this gene is ltaS [H]

Identifier: 222150719

GI number: 222150719

Start: 494750

End: 496681

Strand: Direct

Name: ltaS [H]

Synonym: MCCL_0469

Alternate gene names: 222150719

Gene position: 494750-496681 (Clockwise)

Preceding gene: 222150718

Following gene: 222150721

Centisome position: 23.53

GC content: 34.11

Gene sequence:

>1932_bases
ATGAAAGATAAAAGGATTACAGTTTTTATGTTTTTCCTGTTGACTGTTATCACAGTTTCGATAAAGACATATTTTGCCTA
TTATATTGATTTATCATTAGGTGTTAAAGGATTAATCCAGAACTTAATATTACTGATGAACCCCTATAGTTTGGTTGCAC
TAATTTTAAGTGTGTTTTTATTCTTTAAAGGTAGAAAAGCTTATTGGTTCATTTATATCGGAGGATTTCTGTTAACATTC
CTTCTTTATTCTAATGTCGTTTACTTCAGATTTTTCTCAGATTTTATTACTTTTAGTACTTTAAACCAGGTGAGCAACGT
AGAATCCATGTCAGGAGCGTTGTGGAGTTCATTTAAATGGTATGACTTTATCTATTTTCTGGATATTTTTGTATTCTTAT
ATTTATTATTGATGAAAAAGCAGTACTTTTCTACGCGTTCATTCAAGAAGAAGTATATCCCAGTTGTGATGGGTGTTTCA
GTATCTTTATTTTTTCTGAACCTTGCCTTTGCGGAAACTGATCGTCCGGAATTATTAACAAGAACGTTTGACCATAAATA
TTTAGTCAAATATCTTGGGCCGTATAACTTTACCGTATATGATGGTATCCAGACGATTCAGAACAACCAGCAAAAAGCAC
ATGCGAGCTCGGATGACTTAGCGCAAGTGCAGTCATATACAAAAACGAAATATGCTGCGCCGAATGGTGCTACATTTGGT
ATTGCTAAAGAGAAGAATGTGATTAAGATTCATCTTGAAAGCTTCCAGACATTCCTGATTAACTATAAAGTGAACGGCGA
GGAAGTAACACCATTCTTAAATTCACTTGCTTCAGGAAATAAAGATTTTATTTATTATGATAATTTCTTCCATCAGACTG
GCCAAGGTAAGACAAGCGATTCAGAGTTAACAATGGATAACTCAATTTATGGCTTACAGCAAGGTTCAGCTTATTCACTG
AAAGGTGATAATACGTATCAGTCGTTACCTGCAATCATGAATCAGCAGCAAGGTTATTCAACTTCTGTTATGCATGGTGA
TTATAAAACATTCTGGAACAGAGATCAGGTGTATAAACACTTCGGTATCGATAAATTCTATGATGCGACGTATTATGATA
TGAGCGAGAAAAATTTAGAGAACCTAGGACTTAAAGACAAAGAGTTCTTCAAAGAGTCAGTACCATATTTAAAGAATGAG
AAACAACCGTTCTACGCTCATTTGATCACATTAACTAATCACTATCCATTTACAATTGATAAAAATGAAGCAACAATAGA
TTCACCTGAAACTGGTAACCCTACTGTCGATGGTTATGTACAAACTGCAAGATATCTAGATGAAGCAGTTCAGCAGTTTA
TAGAAGATCTAAAAAAAGAAGGACTCTATGATGATTCTGTAATATTAATTTACGGCGATCATTATGGTATATCTGAAAAC
CATAATAAAGCGATGGCAAAATTATTAGGTGAAGAAATTACGCCAACAAAATTTATGGACCTACAACGTACAGGTCTATT
CCTTAAAGTGCCAGGTGTTGAAGGTAAGGTAGATCATACGTATGCAGCTCAGGTCGATGTAGCACCTACTTTATTACATC
TACTTGGAATTGACGCAAAACCTTATGTAATGTTTGGAACGGACTTATTCTCTAAACAGCACAAGGATACTGTAACATTT
AGAAATGGTGATTTCATAACACCGGATTATAAATCGATTAATGGTATCTTTTATAGTAATAAAACAAACCAGCCGCTAAC
AGATAAAACAGAAAAGGCTGCAGCGGAGGCAATAAAAAGACAAGCTGAAAAAGAATTAGAAATGTCTGATGCGCTTATCA
ATGGTGACTTATTAAGATTCTATAACAATCCAGAGTTTGAGAAAATTAACGCTTCAAAATACCATTATGATAATGGGGAC
GTATCTCAATAA

Upstream 100 bases:

>100_bases
GACTGTTACAAAGAATAATTCATTGTAAGTATTATAAACATCATTAAATAAAAATATTGCCTGGAGTATATAGATAGTCT
GAATAAATGGAGGTATGAAG

Downstream 100 bases:

>100_bases
TAAAAAAACCAGTCAATATAGAAATCCATTTAGGTTTTCTGTATTGACTGGTTTTTATTTTACAGCGAGTCAGTCCGCGT
TTTTTCCAACCTTAGCCCAA

Product: sulfatase family protein

Products: NA

Alternate protein names: LTA synthase; Polyglycerol phosphate synthase [H]

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MKDKRITVFMFFLLTVITVSIKTYFAYYIDLSLGVKGLIQNLILLMNPYSLVALILSVFLFFKGRKAYWFIYIGGFLLTF
LLYSNVVYFRFFSDFITFSTLNQVSNVESMSGALWSSFKWYDFIYFLDIFVFLYLLLMKKQYFSTRSFKKKYIPVVMGVS
VSLFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGIQTIQNNQQKAHASSDDLAQVQSYTKTKYAAPNGATFG
IAKEKNVIKIHLESFQTFLINYKVNGEEVTPFLNSLASGNKDFIYYDNFFHQTGQGKTSDSELTMDNSIYGLQQGSAYSL
KGDNTYQSLPAIMNQQQGYSTSVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSEKNLENLGLKDKEFFKESVPYLKNE
KQPFYAHLITLTNHYPFTIDKNEATIDSPETGNPTVDGYVQTARYLDEAVQQFIEDLKKEGLYDDSVILIYGDHYGISEN
HNKAMAKLLGEEITPTKFMDLQRTGLFLKVPGVEGKVDHTYAAQVDVAPTLLHLLGIDAKPYVMFGTDLFSKQHKDTVTF
RNGDFITPDYKSINGIFYSNKTNQPLTDKTEKAAAEAIKRQAEKELEMSDALINGDLLRFYNNPEFEKINASKYHYDNGD
VSQ

Sequences:

>Translated_643_residues
MKDKRITVFMFFLLTVITVSIKTYFAYYIDLSLGVKGLIQNLILLMNPYSLVALILSVFLFFKGRKAYWFIYIGGFLLTF
LLYSNVVYFRFFSDFITFSTLNQVSNVESMSGALWSSFKWYDFIYFLDIFVFLYLLLMKKQYFSTRSFKKKYIPVVMGVS
VSLFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGIQTIQNNQQKAHASSDDLAQVQSYTKTKYAAPNGATFG
IAKEKNVIKIHLESFQTFLINYKVNGEEVTPFLNSLASGNKDFIYYDNFFHQTGQGKTSDSELTMDNSIYGLQQGSAYSL
KGDNTYQSLPAIMNQQQGYSTSVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSEKNLENLGLKDKEFFKESVPYLKNE
KQPFYAHLITLTNHYPFTIDKNEATIDSPETGNPTVDGYVQTARYLDEAVQQFIEDLKKEGLYDDSVILIYGDHYGISEN
HNKAMAKLLGEEITPTKFMDLQRTGLFLKVPGVEGKVDHTYAAQVDVAPTLLHLLGIDAKPYVMFGTDLFSKQHKDTVTF
RNGDFITPDYKSINGIFYSNKTNQPLTDKTEKAAAEAIKRQAEKELEMSDALINGDLLRFYNNPEFEKINASKYHYDNGD
VSQ
>Mature_643_residues
MKDKRITVFMFFLLTVITVSIKTYFAYYIDLSLGVKGLIQNLILLMNPYSLVALILSVFLFFKGRKAYWFIYIGGFLLTF
LLYSNVVYFRFFSDFITFSTLNQVSNVESMSGALWSSFKWYDFIYFLDIFVFLYLLLMKKQYFSTRSFKKKYIPVVMGVS
VSLFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGIQTIQNNQQKAHASSDDLAQVQSYTKTKYAAPNGATFG
IAKEKNVIKIHLESFQTFLINYKVNGEEVTPFLNSLASGNKDFIYYDNFFHQTGQGKTSDSELTMDNSIYGLQQGSAYSL
KGDNTYQSLPAIMNQQQGYSTSVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSEKNLENLGLKDKEFFKESVPYLKNE
KQPFYAHLITLTNHYPFTIDKNEATIDSPETGNPTVDGYVQTARYLDEAVQQFIEDLKKEGLYDDSVILIYGDHYGISEN
HNKAMAKLLGEEITPTKFMDLQRTGLFLKVPGVEGKVDHTYAAQVDVAPTLLHLLGIDAKPYVMFGTDLFSKQHKDTVTF
RNGDFITPDYKSINGIFYSNKTNQPLTDKTEKAAAEAIKRQAEKELEMSDALINGDLLRFYNNPEFEKINASKYHYDNGD
VSQ

Specific function: Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate. Is required for staphylococcal growth and cell division process [H]

COG id: COG1368

COG function: function code M; Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily

Gene ontology:

Cell location: Processed glycerol phosphate lipoteichoic acid synthase:Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LTA synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR012160
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: NA

Molecular weight: Translated: 74090; Mature: 74090

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDKRITVFMFFLLTVITVSIKTYFAYYIDLSLGVKGLIQNLILLMNPYSLVALILSVFL
CCCCEEHHHHHHHHHHHHHHHHHHHHHEEEHHHCHHHHHHHHHHHHCCHHHHHHHHHHHH
FFKGRKAYWFIYIGGFLLTFLLYSNVVYFRFFSDFITFSTLNQVSNVESMSGALWSSFKW
HHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
YDFIYFLDIFVFLYLLLMKKQYFSTRSFKKKYIPVVMGVSVSLFFLNLAFAETDRPELLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCCHHHHH
RTFDHKYLVKYLGPYNFTVYDGIQTIQNNQQKAHASSDDLAQVQSYTKTKYAAPNGATFG
HHCCHHHHHHHCCCCCEEEEHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEE
IAKEKNVIKIHLESFQTFLINYKVNGEEVTPFLNSLASGNKDFIYYDNFFHQTGQGKTSD
EECCCCEEEEEEECEEEEEEEEEECCHHHHHHHHHHHCCCCCEEEECCHHHCCCCCCCCC
SELTMDNSIYGLQQGSAYSLKGDNTYQSLPAIMNQQQGYSTSVMHGDYKTFWNRDQVYKH
CCEEECCCEEEECCCCEEEECCCCHHHHHHHHHCCCCCCCEEEEECCHHHHCCHHHHHHH
FGIDKFYDATYYDMSEKNLENLGLKDKEFFKESVPYLKNEKQPFYAHLITLTNHYPFTID
CCCCHHCCCCEECCCCCCHHHCCCCHHHHHHHCCCHHCCCCCCCEEEEEEEECCCCEEEC
KNEATIDSPETGNPTVDGYVQTARYLDEAVQQFIEDLKKEGLYDDSVILIYGDHYGISEN
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCC
HNKAMAKLLGEEITPTKFMDLQRTGLFLKVPGVEGKVDHTYAAQVDVAPTLLHLLGIDAK
CHHHHHHHHCCCCCCHHHHHHHHCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHCCCCC
PYVMFGTDLFSKQHKDTVTFRNGDFITPDYKSINGIFYSNKTNQPLTDKTEKAAAEAIKR
CEEEECHHHHCCCCCCEEEECCCCCCCCCHHHCCEEEEECCCCCCCCCHHHHHHHHHHHH
QAEKELEMSDALINGDLLRFYNNPEFEKINASKYHYDNGDVSQ
HHHHHHHHHHHHHCCCHHEECCCCCCCEECCCEEECCCCCCCC
>Mature Secondary Structure
MKDKRITVFMFFLLTVITVSIKTYFAYYIDLSLGVKGLIQNLILLMNPYSLVALILSVFL
CCCCEEHHHHHHHHHHHHHHHHHHHHHEEEHHHCHHHHHHHHHHHHCCHHHHHHHHHHHH
FFKGRKAYWFIYIGGFLLTFLLYSNVVYFRFFSDFITFSTLNQVSNVESMSGALWSSFKW
HHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
YDFIYFLDIFVFLYLLLMKKQYFSTRSFKKKYIPVVMGVSVSLFFLNLAFAETDRPELLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCCHHHHH
RTFDHKYLVKYLGPYNFTVYDGIQTIQNNQQKAHASSDDLAQVQSYTKTKYAAPNGATFG
HHCCHHHHHHHCCCCCEEEEHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEE
IAKEKNVIKIHLESFQTFLINYKVNGEEVTPFLNSLASGNKDFIYYDNFFHQTGQGKTSD
EECCCCEEEEEEECEEEEEEEEEECCHHHHHHHHHHHCCCCCEEEECCHHHCCCCCCCCC
SELTMDNSIYGLQQGSAYSLKGDNTYQSLPAIMNQQQGYSTSVMHGDYKTFWNRDQVYKH
CCEEECCCEEEECCCCEEEECCCCHHHHHHHHHCCCCCCCEEEEECCHHHHCCHHHHHHH
FGIDKFYDATYYDMSEKNLENLGLKDKEFFKESVPYLKNEKQPFYAHLITLTNHYPFTID
CCCCHHCCCCEECCCCCCHHHCCCCHHHHHHHCCCHHCCCCCCCEEEEEEEECCCCEEEC
KNEATIDSPETGNPTVDGYVQTARYLDEAVQQFIEDLKKEGLYDDSVILIYGDHYGISEN
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCC
HNKAMAKLLGEEITPTKFMDLQRTGLFLKVPGVEGKVDHTYAAQVDVAPTLLHLLGIDAK
CHHHHHHHHCCCCCCHHHHHHHHCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHCCCCC
PYVMFGTDLFSKQHKDTVTFRNGDFITPDYKSINGIFYSNKTNQPLTDKTEKAAAEAIKR
CEEEECHHHHCCCCCCEEEECCCCCCCCCHHHCCEEEEECCCCCCCCCHHHHHHHHHHHH
QAEKELEMSDALINGDLLRFYNNPEFEKINASKYHYDNGDVSQ
HHHHHHHHHHHHHCCCHHEECCCCCCCEECCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA