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The map label for this gene is ina [H]

Identifier: 222150689

GI number: 222150689

Start: 466040

End: 467725

Strand: Direct

Name: ina [H]

Synonym: MCCL_0439

Alternate gene names: 222150689

Gene position: 466040-467725 (Clockwise)

Preceding gene: 222150688

Following gene: 222150690

Centisome position: 22.17

GC content: 36.71

Gene sequence:

>1686_bases
GTGAAGCTTATAAAGTTGATTGTGAGTATTGGAATATGTTCATTAGCATTTACTTGTAATGTTCAGGCAACTGAGAAACA
GCCAAATAATAATGTACAGTTGCAGAACGCTGAAAAAGTAAAGACAAAACCGATAATTACCCAGAAGAAGACAGTTCAGA
CGAAAGCAATACCACCTTTTAAATCCAAACCTTATAACGGGCCGGTCATTAATGAAAATGTACTGGTTGTATTGATGGAT
TTTAGTAATGCACCGCATGGAAAGCTTACGCAGAAGGATACCGAAAATTATATAAAATCATATGATAGGAAATACTATCA
AGACCTGTTCTTCGGTAAGAATGTCACAGGTCCAGGAGGATACAAATATCAATCACTTAAATCCTATTATAATAGTGCAT
CTAGTGGTAGTCTGTCATTAACAGGGCAAGTAGCAGGATGGTATCGTGCGAAACATCCGATTCAATATTACGGCGCTAAC
AATGATGCGCGGGCTTCTGAGCTGGTTATGGAAGCAGCAGCAAAAGTTGCTAAAGATAAAAGGATTGATATGAAACGCTA
TGACAGATTTGATTATTATGATCTTGATAAAGATAAAAAAGTAAATGAACCCGATGGTATTATCGATAAGTTTGTTGTTG
TATATAGTGGTATCGGTGAAAGCGAAGGCGGCGGGAAATTTGGGCAGAATACAATCTGGGAACATGTTTCCGAAGTACCA
TTCACTAAAGATAATAAGCCGTCAATAATTCCTGGAACCTATAGCAAGACTTCAAAGTTTTTAAAGAAACGACTTGCAAT
TGCAGAATATGGCATGATATCTGAAGACAGTACAGTAGGAACAGTAGCACATGAGTTCGGACATATGCTTGGTCTACCTG
ATGAATATGACACAGCAAGTAGCTCGGTGAGTCATGCAGGTGAACCCGTTCGTTACTGGTCGCTTATGAGTTATGGTAAA
GATGCCGGAAAGATTCCTGGATTGAATCCTGTCAGTATGAGCCCTTATGCTAAGATGCTTATTCAGAGAATCTACGGTGG
TAACTGGATTCGTATCAATGAAGTAGATTATAAGCAGATTAGTTCGAAGAAAAAGTATTACTTGCTGGATCAATCTGCTT
ATAAAGGACAGAACAATAACGTCATTAAAGTAAACTTGCCTCCGCTACAAAAGAAAGTAAAGGGTAAGCTAAAGAGCTAT
AAGCGCTATTATTTAATTGAGTGGAGGAATCATACAGGTTTAGATATCGGTTTATCGAGAATTAAAGATTCTTTTGGCAT
AAATAAATATGGTAAAGGAATGCTTGTGTGGTATGTGAATGAATATTATAAAGATAATAGTAATTTATCTAAACATTTTG
GTGAAAGTTTGATTGGCGTAGTCGATGCGAGTCCTGGAAATATCCGTACTGCTGGTGGATATATGCCGATGACAGATATA
CAAATTTTTGATGCGCCATTCAATACAAGATCGTTTGGGCAATACAATTCGAATAAAAACTACTTCTTCAAGAAGAAATC
TACAGCACCAGTACTACTTTTTGATGACAGGAATTATTCGAAAAAAGCGATGTTAAATATGCAGGCCCCAGATAGTAGCC
GTGTATTACCTCAACTTGGTATTAAAATTAAAGTAGAAGACCAAAATAAAGAAGGTACTGTCGGAAAGATCAGTATATAT
AAATAA

Upstream 100 bases:

>100_bases
CAAGAGAAACATCACATTCAGTTACGATTAAAGTGTATGTGAAAGGACGAATGATTGATAGTAAGCGTATAGACATAAAT
AGCTGAAAAGAGGTCGGACA

Downstream 100 bases:

>100_bases
GGGGTAATCGATGACATACTTTGAAACGGAACGTCTCATTTTTAGAAATTGGCATAACGCAGATCTTGCGCATTATATTG
AACTGAACCGGAATTTTGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MKLIKLIVSIGICSLAFTCNVQATEKQPNNNVQLQNAEKVKTKPIITQKKTVQTKAIPPFKSKPYNGPVINENVLVVLMD
FSNAPHGKLTQKDTENYIKSYDRKYYQDLFFGKNVTGPGGYKYQSLKSYYNSASSGSLSLTGQVAGWYRAKHPIQYYGAN
NDARASELVMEAAAKVAKDKRIDMKRYDRFDYYDLDKDKKVNEPDGIIDKFVVVYSGIGESEGGGKFGQNTIWEHVSEVP
FTKDNKPSIIPGTYSKTSKFLKKRLAIAEYGMISEDSTVGTVAHEFGHMLGLPDEYDTASSSVSHAGEPVRYWSLMSYGK
DAGKIPGLNPVSMSPYAKMLIQRIYGGNWIRINEVDYKQISSKKKYYLLDQSAYKGQNNNVIKVNLPPLQKKVKGKLKSY
KRYYLIEWRNHTGLDIGLSRIKDSFGINKYGKGMLVWYVNEYYKDNSNLSKHFGESLIGVVDASPGNIRTAGGYMPMTDI
QIFDAPFNTRSFGQYNSNKNYFFKKKSTAPVLLFDDRNYSKKAMLNMQAPDSSRVLPQLGIKIKVEDQNKEGTVGKISIY
K

Sequences:

>Translated_561_residues
MKLIKLIVSIGICSLAFTCNVQATEKQPNNNVQLQNAEKVKTKPIITQKKTVQTKAIPPFKSKPYNGPVINENVLVVLMD
FSNAPHGKLTQKDTENYIKSYDRKYYQDLFFGKNVTGPGGYKYQSLKSYYNSASSGSLSLTGQVAGWYRAKHPIQYYGAN
NDARASELVMEAAAKVAKDKRIDMKRYDRFDYYDLDKDKKVNEPDGIIDKFVVVYSGIGESEGGGKFGQNTIWEHVSEVP
FTKDNKPSIIPGTYSKTSKFLKKRLAIAEYGMISEDSTVGTVAHEFGHMLGLPDEYDTASSSVSHAGEPVRYWSLMSYGK
DAGKIPGLNPVSMSPYAKMLIQRIYGGNWIRINEVDYKQISSKKKYYLLDQSAYKGQNNNVIKVNLPPLQKKVKGKLKSY
KRYYLIEWRNHTGLDIGLSRIKDSFGINKYGKGMLVWYVNEYYKDNSNLSKHFGESLIGVVDASPGNIRTAGGYMPMTDI
QIFDAPFNTRSFGQYNSNKNYFFKKKSTAPVLLFDDRNYSKKAMLNMQAPDSSRVLPQLGIKIKVEDQNKEGTVGKISIY
K
>Mature_561_residues
MKLIKLIVSIGICSLAFTCNVQATEKQPNNNVQLQNAEKVKTKPIITQKKTVQTKAIPPFKSKPYNGPVINENVLVVLMD
FSNAPHGKLTQKDTENYIKSYDRKYYQDLFFGKNVTGPGGYKYQSLKSYYNSASSGSLSLTGQVAGWYRAKHPIQYYGAN
NDARASELVMEAAAKVAKDKRIDMKRYDRFDYYDLDKDKKVNEPDGIIDKFVVVYSGIGESEGGGKFGQNTIWEHVSEVP
FTKDNKPSIIPGTYSKTSKFLKKRLAIAEYGMISEDSTVGTVAHEFGHMLGLPDEYDTASSSVSHAGEPVRYWSLMSYGK
DAGKIPGLNPVSMSPYAKMLIQRIYGGNWIRINEVDYKQISSKKKYYLLDQSAYKGQNNNVIKVNLPPLQKKVKGKLKSY
KRYYLIEWRNHTGLDIGLSRIKDSFGINKYGKGMLVWYVNEYYKDNSNLSKHFGESLIGVVDASPGNIRTAGGYMPMTDI
QIFDAPFNTRSFGQYNSNKNYFFKKKSTAPVLLFDDRNYSKKAMLNMQAPDSSRVLPQLGIKIKVEDQNKEGTVGKISIY
K

Specific function: Neutral metalloprotease that is secreted to degrade antibacterial proteins produced by the insect host for its defense (attacins and cecropins). Probably degrades some unknown crucial protein(s) too, since it is toxic when injected to insect larvae [H]

COG id: COG4412

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M6 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012300
- InterPro:   IPR008757 [H]

Pfam domain/function: PF05547 Peptidase_M6 [H]

EC number: NA

Molecular weight: Translated: 63299; Mature: 63299

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIKLIVSIGICSLAFTCNVQATEKQPNNNVQLQNAEKVKTKPIITQKKTVQTKAIPPF
CHHHHHHHHHHHHHEEEEECEEECCCCCCCCEEECCCHHCCCCCCEECCHHHHHCCCCCC
KSKPYNGPVINENVLVVLMDFSNAPHGKLTQKDTENYIKSYDRKYYQDLFFGKNVTGPGG
CCCCCCCCEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
YKYQSLKSYYNSASSGSLSLTGQVAGWYRAKHPIQYYGANNDARASELVMEAAAKVAKDK
CCHHHHHHHHCCCCCCCEEEEEEECCHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHC
RIDMKRYDRFDYYDLDKDKKVNEPDGIIDKFVVVYSGIGESEGGGKFGQNTIWEHVSEVP
CCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCC
FTKDNKPSIIPGTYSKTSKFLKKRLAIAEYGMISEDSTVGTVAHEFGHMLGLPDEYDTAS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCH
SSVSHAGEPVRYWSLMSYGKDAGKIPGLNPVSMSPYAKMLIQRIYGGNWIRINEVDYKQI
HHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCHHHH
SSKKKYYLLDQSAYKGQNNNVIKVNLPPLQKKVKGKLKSYKRYYLIEWRNHTGLDIGLSR
CCCCCEEEEECHHCCCCCCCEEEEECCHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHH
IKDSFGINKYGKGMLVWYVNEYYKDNSNLSKHFGESLIGVVDASPGNIRTAGGYMPMTDI
HHHHCCCCCCCCEEEEEEEEHHHCCCCCHHHHHCCCEEEEEECCCCCEEECCCCCCCCCE
QIFDAPFNTRSFGQYNSNKNYFFKKKSTAPVLLFDDRNYSKKAMLNMQAPDSSRVLPQLG
EEEECCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCEEEEEECCCCCCCCHHHCC
IKIKVEDQNKEGTVGKISIYK
CEEEEECCCCCCCEEEEEEEC
>Mature Secondary Structure
MKLIKLIVSIGICSLAFTCNVQATEKQPNNNVQLQNAEKVKTKPIITQKKTVQTKAIPPF
CHHHHHHHHHHHHHEEEEECEEECCCCCCCCEEECCCHHCCCCCCEECCHHHHHCCCCCC
KSKPYNGPVINENVLVVLMDFSNAPHGKLTQKDTENYIKSYDRKYYQDLFFGKNVTGPGG
CCCCCCCCEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
YKYQSLKSYYNSASSGSLSLTGQVAGWYRAKHPIQYYGANNDARASELVMEAAAKVAKDK
CCHHHHHHHHCCCCCCCEEEEEEECCHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHC
RIDMKRYDRFDYYDLDKDKKVNEPDGIIDKFVVVYSGIGESEGGGKFGQNTIWEHVSEVP
CCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCC
FTKDNKPSIIPGTYSKTSKFLKKRLAIAEYGMISEDSTVGTVAHEFGHMLGLPDEYDTAS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCH
SSVSHAGEPVRYWSLMSYGKDAGKIPGLNPVSMSPYAKMLIQRIYGGNWIRINEVDYKQI
HHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCHHHH
SSKKKYYLLDQSAYKGQNNNVIKVNLPPLQKKVKGKLKSYKRYYLIEWRNHTGLDIGLSR
CCCCCEEEEECHHCCCCCCCEEEEECCHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHH
IKDSFGINKYGKGMLVWYVNEYYKDNSNLSKHFGESLIGVVDASPGNIRTAGGYMPMTDI
HHHHCCCCCCCCEEEEEEEEHHHCCCCCHHHHHCCCEEEEEECCCCCEEECCCCCCCCCE
QIFDAPFNTRSFGQYNSNKNYFFKKKSTAPVLLFDDRNYSKKAMLNMQAPDSSRVLPQLG
EEEECCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCEEEEEECCCCCCCCHHHCC
IKIKVEDQNKEGTVGKISIYK
CEEEEECCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2089225; 6421577 [H]