Click here to switch to the map view.

The map label for this gene is cdr [H]

Identifier: 222150633

GI number: 222150633

Start: 410018

End: 412456

Strand: Direct

Name: cdr [H]

Synonym: MCCL_0383

Alternate gene names: 222150633

Gene position: 410018-412456 (Clockwise)

Preceding gene: 222150631

Following gene: 222150634

Centisome position: 19.5

GC content: 39.57

Gene sequence:

>2439_bases
ATGAGAAAGATTATGATAATCGGTGGTGTTGCAGCTGGCGCATCTGTAGCAGCACGCTTAAGACGATTAAATGAACAAGA
TGAAATAACAATTATTGAAAGAGGTCCGCATGTATCATTTGCAAACTGTGGATTACCTTATTATATCGGTGATGAAATAC
AAGATAGAGATAAATTATTAATTCAAACACCTGAACTGATGAATGAGCGTATGAATATTAACGTCAGAACCAATACGGAA
GCAACTCAGATCAATCCAGATAATAAAACAGTCTTACTAAAAACACAGAATGGGGTCGAAGAAGCTTCATATGATGTTCT
TATTCTTTCGATGGGAGCGCGTGCGATCGAAGTACCGATTGAAGGTGCAAAACAAAACCATGTCTTTACTCTAAGAAATA
TTCCGGATATGGATAAAATAAAATCTTATATAAACGAGCACGATGTTAAAACAGCGTCTGTCGTTGGTGGAGGATTTATT
GGGTTAGAGATGGCTGAGAATTTACATGCATTAGGAATTGATGTAACACTGTTTGAGCTTGGGGATCAAGTGATGACGGG
CATGGATAAAGATATGACTAAATTATTAGAAACACATATGGTGCAGCGTGGTGTCCATTTAAAGTTAAAATCTTCTATTA
AAGAAATTAATGAGCATAATGTCATTGCAGAAAATGGAGATGTCATTCAAAGTGATATGGTCATTATGGCGATAGGGGTC
ATTCCAGAGTCTGCAATTGCTCAAGAAGCAGGGATTGAGACGGGTGCTAAAGGTGCTATCAAGACAAATGATGTATTTGA
AACATCAATAAAGGATATTTATGCTATTGGTGATGTTGCTGAGATTACACATAAGATTTCACAGCAGGATGTGCATATTC
CACTTGCGTGGATTGCGAATCGAGAAGGACGTCTCCTTGCTGATTACCTTAATGGAAAGGTGATTGAAAAGATAAAACCG
ATCGGCACAGCAATTGCGAAAGTATTTGATCTCACCGCAGCAAGCACAGGACTTAATGAACGTACATTGAAGATGCAGGG
ACTTGATTATCATATTATTCATGTATCTGGACAATCGAATGCGACCTATTATCCAGGCGCTGAGCCGATGACGATCAAGG
CGCTGTTTAGTCCTGAAGGCAAAATTTATGGGGCGCAGATTGTAGGACGTAAAGGTGTGGATAAACGTATCGATTTAATT
GCGAGCGCTATGACATTTAACCAGGATATTAGAAGCCTCGCTCAAATTGAAATTGCATATGCACCACCATTTTCATCAGC
AAAAGATCCGGTTAACATGGTGGGTTATATCGCACAAAACGTACTGGATGATGAGATGAAGATGGTTCAATACGATGAAA
TCGAAAATTTTAATCAATTGATAGATGTACGTGAACCAATTGAATACGACATGGGTACTATTGGCAGTGCGAAGAATATT
CCACTTGGCACGCTGCGTGATCGTCTAGCTGAACTTGATATAAATGAACCAGTAGCAATCTTCTGCCAAGTCGGTCAGCG
TGGTTATAATGCAGCACGTATATTACAGAATAATGGATTCGATGTCGTCAATCTTGATGGTGGATATAAACATTACAAAG
CGATGCATGAAACAGTAAATAGACCGGAAGTAAGAGCGGTTGAACAAACACAGATTGAAGAAGGTACTAAGAAGGAGCAG
CCGATGAAAAAAGATGATAGACGTATTATTGAAGCAAGTGGACTACAGTGTCCTGGCCCTATCCTAAAAGTAAAAGAAAA
TATGGATGAAATGAAAGACGGAGAGCAGCTTGAGATTCATGTGACGGATTTCGGTTTTTGTACAGATATCGAAGCTTGGG
CTAAGAATACAGGAAATACAATGATCAGCAACGAAATGAAGGATGGTAAAGTCGTTGCAGTAGTACAAAAAGGTGCTGAC
TTACCGATTAACGTGATGAACGGCAGAGAAGGACATCAGCTTGTTGAGACGAAGAATGGTGCAACGATGGTTGTATTCAG
TGGCGATCTTGATAAGGCGTTAGCTTCATTTATTATTGCAACAGGTGCAGCATCATATGGTAAGGAAGTGACGATGTTCT
TCACTTTCTGGGGCCTTAATGTGATTAAGAAACCTGGTGTGACTGTTGCAAAAGAAGGGCTCGATAAAATGTTCAGCAAG
ATGATGCCGAAACATGCAGGAAAACTCCCGATATCTAAGATGAATATGGGTGGTGCAGGTGCACGTATGATTCGTCACGT
AATGAACAAGAAGAAAGTAGATTCTTTAGAAACAATGATCGAAAAGGCCCAATCGATGGGTATTAAGATGGTTGCATGTA
CGATGAGCATGGATATTATGGCAGTGACAAAAGAAGAGTTAATCGATGGCGTTGAGTTTGGCGGTGTTGCAACATATCTC
GGTGATACAGAACAATCGAACTTAAACTTATTTATTTAG

Upstream 100 bases:

>100_bases
AGGTATATATGTCAATTAAAAAATACCCCGCAAGGTATTTGACAAAGGAATTTGTTCGTTGTATGATACCCCCACAGGTA
TAGAAAGAGGAGGAAACAAT

Downstream 100 bases:

>100_bases
GAGGCATATGATGTATTTTAAACAATTTTTTAATGAGCAACTTGCACAGTATTCTTATTTAGTAGGATGTCAAAAAACAG
GAGAAGCTATTGTCATTGAT

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 812; Mature: 812

Protein sequence:

>812_residues
MRKIMIIGGVAAGASVAARLRRLNEQDEITIIERGPHVSFANCGLPYYIGDEIQDRDKLLIQTPELMNERMNINVRTNTE
ATQINPDNKTVLLKTQNGVEEASYDVLILSMGARAIEVPIEGAKQNHVFTLRNIPDMDKIKSYINEHDVKTASVVGGGFI
GLEMAENLHALGIDVTLFELGDQVMTGMDKDMTKLLETHMVQRGVHLKLKSSIKEINEHNVIAENGDVIQSDMVIMAIGV
IPESAIAQEAGIETGAKGAIKTNDVFETSIKDIYAIGDVAEITHKISQQDVHIPLAWIANREGRLLADYLNGKVIEKIKP
IGTAIAKVFDLTAASTGLNERTLKMQGLDYHIIHVSGQSNATYYPGAEPMTIKALFSPEGKIYGAQIVGRKGVDKRIDLI
ASAMTFNQDIRSLAQIEIAYAPPFSSAKDPVNMVGYIAQNVLDDEMKMVQYDEIENFNQLIDVREPIEYDMGTIGSAKNI
PLGTLRDRLAELDINEPVAIFCQVGQRGYNAARILQNNGFDVVNLDGGYKHYKAMHETVNRPEVRAVEQTQIEEGTKKEQ
PMKKDDRRIIEASGLQCPGPILKVKENMDEMKDGEQLEIHVTDFGFCTDIEAWAKNTGNTMISNEMKDGKVVAVVQKGAD
LPINVMNGREGHQLVETKNGATMVVFSGDLDKALASFIIATGAASYGKEVTMFFTFWGLNVIKKPGVTVAKEGLDKMFSK
MMPKHAGKLPISKMNMGGAGARMIRHVMNKKKVDSLETMIEKAQSMGIKMVACTMSMDIMAVTKEELIDGVEFGGVATYL
GDTEQSNLNLFI

Sequences:

>Translated_812_residues
MRKIMIIGGVAAGASVAARLRRLNEQDEITIIERGPHVSFANCGLPYYIGDEIQDRDKLLIQTPELMNERMNINVRTNTE
ATQINPDNKTVLLKTQNGVEEASYDVLILSMGARAIEVPIEGAKQNHVFTLRNIPDMDKIKSYINEHDVKTASVVGGGFI
GLEMAENLHALGIDVTLFELGDQVMTGMDKDMTKLLETHMVQRGVHLKLKSSIKEINEHNVIAENGDVIQSDMVIMAIGV
IPESAIAQEAGIETGAKGAIKTNDVFETSIKDIYAIGDVAEITHKISQQDVHIPLAWIANREGRLLADYLNGKVIEKIKP
IGTAIAKVFDLTAASTGLNERTLKMQGLDYHIIHVSGQSNATYYPGAEPMTIKALFSPEGKIYGAQIVGRKGVDKRIDLI
ASAMTFNQDIRSLAQIEIAYAPPFSSAKDPVNMVGYIAQNVLDDEMKMVQYDEIENFNQLIDVREPIEYDMGTIGSAKNI
PLGTLRDRLAELDINEPVAIFCQVGQRGYNAARILQNNGFDVVNLDGGYKHYKAMHETVNRPEVRAVEQTQIEEGTKKEQ
PMKKDDRRIIEASGLQCPGPILKVKENMDEMKDGEQLEIHVTDFGFCTDIEAWAKNTGNTMISNEMKDGKVVAVVQKGAD
LPINVMNGREGHQLVETKNGATMVVFSGDLDKALASFIIATGAASYGKEVTMFFTFWGLNVIKKPGVTVAKEGLDKMFSK
MMPKHAGKLPISKMNMGGAGARMIRHVMNKKKVDSLETMIEKAQSMGIKMVACTMSMDIMAVTKEELIDGVEFGGVATYL
GDTEQSNLNLFI
>Mature_812_residues
MRKIMIIGGVAAGASVAARLRRLNEQDEITIIERGPHVSFANCGLPYYIGDEIQDRDKLLIQTPELMNERMNINVRTNTE
ATQINPDNKTVLLKTQNGVEEASYDVLILSMGARAIEVPIEGAKQNHVFTLRNIPDMDKIKSYINEHDVKTASVVGGGFI
GLEMAENLHALGIDVTLFELGDQVMTGMDKDMTKLLETHMVQRGVHLKLKSSIKEINEHNVIAENGDVIQSDMVIMAIGV
IPESAIAQEAGIETGAKGAIKTNDVFETSIKDIYAIGDVAEITHKISQQDVHIPLAWIANREGRLLADYLNGKVIEKIKP
IGTAIAKVFDLTAASTGLNERTLKMQGLDYHIIHVSGQSNATYYPGAEPMTIKALFSPEGKIYGAQIVGRKGVDKRIDLI
ASAMTFNQDIRSLAQIEIAYAPPFSSAKDPVNMVGYIAQNVLDDEMKMVQYDEIENFNQLIDVREPIEYDMGTIGSAKNI
PLGTLRDRLAELDINEPVAIFCQVGQRGYNAARILQNNGFDVVNLDGGYKHYKAMHETVNRPEVRAVEQTQIEEGTKKEQ
PMKKDDRRIIEASGLQCPGPILKVKENMDEMKDGEQLEIHVTDFGFCTDIEAWAKNTGNTMISNEMKDGKVVAVVQKGAD
LPINVMNGREGHQLVETKNGATMVVFSGDLDKALASFIIATGAASYGKEVTMFFTFWGLNVIKKPGVTVAKEGLDKMFSK
MMPKHAGKLPISKMNMGGAGARMIRHVMNKKKVDSLETMIEKAQSMGIKMVACTMSMDIMAVTKEELIDGVEFGGVATYL
GDTEQSNLNLFI

Specific function: Catalyzes specifically the NADPH-dependent reduction of coenzyme A disulfide [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI226437568, Length=312, Percent_Identity=23.0769230769231, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI65787454, Length=312, Percent_Identity=23.0769230769231, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI21389617, Length=312, Percent_Identity=23.0769230769231, Blast_Score=88, Evalue=3e-17,
Organism=Escherichia coli, GI1789065, Length=288, Percent_Identity=28.4722222222222, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1786307, Length=323, Percent_Identity=25.6965944272446, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1788892, Length=286, Percent_Identity=25.1748251748252, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1789765, Length=266, Percent_Identity=27.0676691729323, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI87082354, Length=344, Percent_Identity=25.2906976744186, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17559934, Length=287, Percent_Identity=25.0871080139373, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 89332; Mature: 89332

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50206 RHODANESE_3 ; PS01148 UPF0033

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIMIIGGVAAGASVAARLRRLNEQDEITIIERGPHVSFANCGLPYYIGDEIQDRDKLL
CCEEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCCEEECCCCCCCCCEE
IQTPELMNERMNINVRTNTEATQINPDNKTVLLKTQNGVEEASYDVLILSMGARAIEVPI
EECHHHHCCCEEEEEEECCCEEEECCCCCEEEEEECCCCCCCCCCEEEEECCCEEEEECC
EGAKQNHVFTLRNIPDMDKIKSYINEHDVKTASVVGGGFIGLEMAENLHALGIDVTLFEL
CCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEECCCEEEHHHHCCCEEEECEEEHHHH
GDQVMTGMDKDMTKLLETHMVQRGVHLKLKSSIKEINEHNVIAENGDVIQSDMVIMAIGV
CHHHHHCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCEEECCCCEEECCEEEEEEEC
IPESAIAQEAGIETGAKGAIKTNDVFETSIKDIYAIGDVAEITHKISQQDVHIPLAWIAN
CCCHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEEEC
REGRLLADYLNGKVIEKIKPIGTAIAKVFDLTAASTGLNERTLKMQGLDYHIIHVSGQSN
CCCCEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEEEECCCC
ATYYPGAEPMTIKALFSPEGKIYGAQIVGRKGVDKRIDLIASAMTFNQDIRSLAQIEIAY
CEECCCCCCEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEE
APPFSSAKDPVNMVGYIAQNVLDDEMKMVQYDEIENFNQLIDVREPIEYDMGTIGSAKNI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
PLGTLRDRLAELDINEPVAIFCQVGQRGYNAARILQNNGFDVVNLDGGYKHYKAMHETVN
CHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHCC
RPEVRAVEQTQIEEGTKKEQPMKKDDRRIIEASGLQCPGPILKVKENMDEMKDGEQLEIH
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCHHHHCCCCEEEEE
VTDFGFCTDIEAWAKNTGNTMISNEMKDGKVVAVVQKGADLPINVMNGREGHQLVETKNG
EECCCCCCCHHHHHCCCCCEEEECCCCCCCEEEEEECCCCCCEEECCCCCCCEEEEECCC
ATMVVFSGDLDKALASFIIATGAASYGKEVTMFFTFWGLNVIKKPGVTVAKEGLDKMFSK
CEEEEECCCHHHHHHHHHHHHCCHHCCCEEEEEEEEECCHHHCCCCCHHHHHHHHHHHHH
MMPKHAGKLPISKMNMGGAGARMIRHVMNKKKVDSLETMIEKAQSMGIKMVACTMSMDIM
HCHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCE
AVTKEELIDGVEFGGVATYLGDTEQSNLNLFI
EECHHHHHCCCCCCCEEEECCCCCCCCCEEEC
>Mature Secondary Structure
MRKIMIIGGVAAGASVAARLRRLNEQDEITIIERGPHVSFANCGLPYYIGDEIQDRDKLL
CCEEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCCEEECCCCCCCCCEE
IQTPELMNERMNINVRTNTEATQINPDNKTVLLKTQNGVEEASYDVLILSMGARAIEVPI
EECHHHHCCCEEEEEEECCCEEEECCCCCEEEEEECCCCCCCCCCEEEEECCCEEEEECC
EGAKQNHVFTLRNIPDMDKIKSYINEHDVKTASVVGGGFIGLEMAENLHALGIDVTLFEL
CCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEECCCEEEHHHHCCCEEEECEEEHHHH
GDQVMTGMDKDMTKLLETHMVQRGVHLKLKSSIKEINEHNVIAENGDVIQSDMVIMAIGV
CHHHHHCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCEEECCCCEEECCEEEEEEEC
IPESAIAQEAGIETGAKGAIKTNDVFETSIKDIYAIGDVAEITHKISQQDVHIPLAWIAN
CCCHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEEEC
REGRLLADYLNGKVIEKIKPIGTAIAKVFDLTAASTGLNERTLKMQGLDYHIIHVSGQSN
CCCCEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEEEECCCC
ATYYPGAEPMTIKALFSPEGKIYGAQIVGRKGVDKRIDLIASAMTFNQDIRSLAQIEIAY
CEECCCCCCEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEE
APPFSSAKDPVNMVGYIAQNVLDDEMKMVQYDEIENFNQLIDVREPIEYDMGTIGSAKNI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
PLGTLRDRLAELDINEPVAIFCQVGQRGYNAARILQNNGFDVVNLDGGYKHYKAMHETVN
CHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHCC
RPEVRAVEQTQIEEGTKKEQPMKKDDRRIIEASGLQCPGPILKVKENMDEMKDGEQLEIH
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCHHHHCCCCEEEEE
VTDFGFCTDIEAWAKNTGNTMISNEMKDGKVVAVVQKGADLPINVMNGREGHQLVETKNG
EECCCCCCCHHHHHCCCCCEEEECCCCCCCEEEEEECCCCCCEEECCCCCCCEEEEECCC
ATMVVFSGDLDKALASFIIATGAASYGKEVTMFFTFWGLNVIKKPGVTVAKEGLDKMFSK
CEEEEECCCHHHHHHHHHHHHCCHHCCCEEEEEEEEECCHHHCCCCCHHHHHHHHHHHHH
MMPKHAGKLPISKMNMGGAGARMIRHVMNKKKVDSLETMIEKAQSMGIKMVACTMSMDIM
HCHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCE
AVTKEELIDGVEFGGVATYLGDTEQSNLNLFI
EECHHHHHCCCCCCCEEEECCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA