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The map label for this gene is glpT [H]

Identifier: 222150620

GI number: 222150620

Start: 393557

End: 394915

Strand: Direct

Name: glpT [H]

Synonym: MCCL_0370

Alternate gene names: 222150620

Gene position: 393557-394915 (Clockwise)

Preceding gene: 222150618

Following gene: 222150621

Centisome position: 18.72

GC content: 43.71

Gene sequence:

>1359_bases
ATGTTAAAGTTTTTACAACCTGCGCCTAAAGCACAGCCTTTAGACAGCAAAGAAGTTGACGCAGAGTACAAGAAGTTACG
CCTGCAGGTCTTTATCGGAATCTTTATTGGTTACGCAGCTTACTATCTGTTAAGAAAGAATTTCTCGCTTGCGATGCCAG
CACTTATTGAACAGGGGTTCACAAAGACCGATCTTGGTTTCGCGTTATCGGCGGTATCTATTGCATACGGTATTAGTAAA
TTTGTGATGGGAACGGTATCAGACAGGAGCCACGCCAGAAACTTCATGGTGCTTGGTCTTGTACTGACAGCAATCGTCAA
CTTGCTGCTTGGTTTTGTTCCGTTCTTTACCTCTTCGATTGCTATTATGTTTGTCTTATTATTCTTGAATGGATGGTTCC
AGGGTATGGGCTGGCCGCCTGCAGGAAGAACATTAGTCCATTGGTTCAGTGTATCTGAGCGTGGGAGTAAGACAGCACTA
TGGAATGTTGCGCATAATGTAGGTGGTGGAGTGATGGCACCGCTTGCTGTATTTGGTATCACACTGTTTACAACATACAA
CTTCGGCTATTTAAAAGGTTTTGAAGGGGCGTTTATCTTTCCAGCACTGATTGCCTTAGTATGTGCTGCAATAACGTTCT
ATTTCATGAAGGATACACCTCAGTCACAAGGATTACCACCGATTGAAGTATATAAGAATGATTATCCGAATAAGGCACAT
GAGACATTGGAAGAAGAATTAACGACGAAAGAGATTCTCTTCAAATATGTACTGAATAACAAGTGGGTCTGGATGATTGC
AATCGCTAATATCTTTGTCTACTTCGTAAGATACGGTGTATTAGACTGGGCACCGACGTATCTTAATGAAGAGAAAGGCT
TTCAGCTTAACGAATCCAGCTGGTCTTACTTCTTATATGAATGGGCAGGTATCCCAGGTACCTTATTGTGTGGCTGGTTA
TCAGATAAAGTATTCAAAGGGCGTCGTGGTCCGGCAGGATTTATCTTTATGATCGGCGTAACGCTTGCAGTAATCGTCTA
CTGGCTGAACCCTGCAGGCAACCCGTGGATTGATAATGTTGCACTGATTACTATCGGGTTCTTGATCTATGGACCGGTAA
TGCTGATTGGCTTACAGGCGCTGGATTATGTACCGAAAAAAGCAGCAGGAACAGCAGCAGGACTTACTGGATTGTTCGGT
TACCTGGCTGGTGCGGTGATGGCGAATATCCTGATGGGAGTAGTCGTTGATAATTTTGGCTGGGATGCAGGATTTATGCT
ATTGGTCGGAGCCTCTGTACTTGCGACATTAAGCTTTACCTTCACGTGGAACGTGCGTGGACAAGAAGTAATTAAATAG

Upstream 100 bases:

>100_bases
ATAATAAGCTTAAACTTTTTGTAAAGGCTTTCTTTACGAATTATGTCTAGTTTGTTAAGATTGTAAAGATAATGTAAATA
TAGAAAACAGGAGGAAATTT

Downstream 100 bases:

>100_bases
GACAAAAAATGCATAGAGTATTCTATGCATTTTTTTTATAATACAGGTAAGGAGGTGTGGAGAATGCTGAAGCTAGAACA
TATCAGTAAACGTTATAGAG

Product: glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MLKFLQPAPKAQPLDSKEVDAEYKKLRLQVFIGIFIGYAAYYLLRKNFSLAMPALIEQGFTKTDLGFALSAVSIAYGISK
FVMGTVSDRSHARNFMVLGLVLTAIVNLLLGFVPFFTSSIAIMFVLLFLNGWFQGMGWPPAGRTLVHWFSVSERGSKTAL
WNVAHNVGGGVMAPLAVFGITLFTTYNFGYLKGFEGAFIFPALIALVCAAITFYFMKDTPQSQGLPPIEVYKNDYPNKAH
ETLEEELTTKEILFKYVLNNKWVWMIAIANIFVYFVRYGVLDWAPTYLNEEKGFQLNESSWSYFLYEWAGIPGTLLCGWL
SDKVFKGRRGPAGFIFMIGVTLAVIVYWLNPAGNPWIDNVALITIGFLIYGPVMLIGLQALDYVPKKAAGTAAGLTGLFG
YLAGAVMANILMGVVVDNFGWDAGFMLLVGASVLATLSFTFTWNVRGQEVIK

Sequences:

>Translated_452_residues
MLKFLQPAPKAQPLDSKEVDAEYKKLRLQVFIGIFIGYAAYYLLRKNFSLAMPALIEQGFTKTDLGFALSAVSIAYGISK
FVMGTVSDRSHARNFMVLGLVLTAIVNLLLGFVPFFTSSIAIMFVLLFLNGWFQGMGWPPAGRTLVHWFSVSERGSKTAL
WNVAHNVGGGVMAPLAVFGITLFTTYNFGYLKGFEGAFIFPALIALVCAAITFYFMKDTPQSQGLPPIEVYKNDYPNKAH
ETLEEELTTKEILFKYVLNNKWVWMIAIANIFVYFVRYGVLDWAPTYLNEEKGFQLNESSWSYFLYEWAGIPGTLLCGWL
SDKVFKGRRGPAGFIFMIGVTLAVIVYWLNPAGNPWIDNVALITIGFLIYGPVMLIGLQALDYVPKKAAGTAAGLTGLFG
YLAGAVMANILMGVVVDNFGWDAGFMLLVGASVLATLSFTFTWNVRGQEVIK
>Mature_452_residues
MLKFLQPAPKAQPLDSKEVDAEYKKLRLQVFIGIFIGYAAYYLLRKNFSLAMPALIEQGFTKTDLGFALSAVSIAYGISK
FVMGTVSDRSHARNFMVLGLVLTAIVNLLLGFVPFFTSSIAIMFVLLFLNGWFQGMGWPPAGRTLVHWFSVSERGSKTAL
WNVAHNVGGGVMAPLAVFGITLFTTYNFGYLKGFEGAFIFPALIALVCAAITFYFMKDTPQSQGLPPIEVYKNDYPNKAH
ETLEEELTTKEILFKYVLNNKWVWMIAIANIFVYFVRYGVLDWAPTYLNEEKGFQLNESSWSYFLYEWAGIPGTLLCGWL
SDKVFKGRRGPAGFIFMIGVTLAVIVYWLNPAGNPWIDNVALITIGFLIYGPVMLIGLQALDYVPKKAAGTAAGLTGLFG
YLAGAVMANILMGVVVDNFGWDAGFMLLVGASVLATLSFTFTWNVRGQEVIK

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=438, Percent_Identity=28.5388127853881, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4503847, Length=438, Percent_Identity=28.5388127853881, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI256219483, Length=438, Percent_Identity=28.5388127853881, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI256219543, Length=462, Percent_Identity=27.7056277056277, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI256219564, Length=369, Percent_Identity=24.9322493224932, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI46361976, Length=378, Percent_Identity=24.8677248677249, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI38093649, Length=462, Percent_Identity=24.6753246753247, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI223717983, Length=462, Percent_Identity=24.6753246753247, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788573, Length=437, Percent_Identity=61.3272311212815, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI87082310, Length=445, Percent_Identity=38.2022471910112, Blast_Score=285, Evalue=4e-78,
Organism=Escherichia coli, GI2367259, Length=425, Percent_Identity=32.9411764705882, Blast_Score=205, Evalue=6e-54,
Organism=Escherichia coli, GI1789152, Length=433, Percent_Identity=22.6327944572748, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87082320, Length=445, Percent_Identity=20.6741573033708, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789515, Length=448, Percent_Identity=22.0982142857143, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI2367379, Length=318, Percent_Identity=23.5849056603774, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17542316, Length=461, Percent_Identity=24.0780911062907, Blast_Score=95, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI133901856, Length=451, Percent_Identity=23.9467849223947, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI133901854, Length=451, Percent_Identity=23.9467849223947, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI133930953, Length=471, Percent_Identity=21.656050955414, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17564202, Length=440, Percent_Identity=24.5454545454545, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17564204, Length=377, Percent_Identity=25.1989389920424, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24656866, Length=478, Percent_Identity=22.1757322175732, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45550478, Length=478, Percent_Identity=22.1757322175732, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24656861, Length=474, Percent_Identity=22.1518987341772, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50067; Mature: 50067

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHHHHHEEEEEEEECCCHHHCC
>Mature Secondary Structure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CCHHHHHHHHHHHHHHEEEEEEEECCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8012593; 9384377 [H]