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The map label for this gene is mntH [H]

Identifier: 222150618

GI number: 222150618

Start: 390492

End: 391502

Strand: Direct

Name: mntH [H]

Synonym: MCCL_0368

Alternate gene names: 222150618

Gene position: 390492-391502 (Clockwise)

Preceding gene: 222150617

Following gene: 222150620

Centisome position: 18.57

GC content: 42.04

Gene sequence:

>1011_bases
ATGAATAAAAGTCTGGAAGAAATAAATGGTAAGGTGTCTTTTGATAGTGAGGCACATGGCATCAAGAAAATGATTATGTA
TTTGGGACCAGGGCTGTTGGTAGCCGTCGGTTATATGGATCCAGGAAACTGGATCACATCAATGGCAGGGGGTGCACAGT
TTGGGTATACGCTGCTCTTTGTCATACTGTTATCCAGTCTGTCAGCGATGCTCTTACAAAGTATGTGCGCGCGTCTAGGG
ATTGCTAGTGGTATGGACCTCGCTCAGGTTATCAAGCATATGAGCAATAAGCCTGTGTCCATCGCTGCATGGGTTGTTAC
AGAGCTTGCAATTATGGCGACAGATATTGCGGAGATCATCGGTAGTGCAATTGCTTTAAATCTGCTGTTCAACATTCCTC
TAGTTATCGGAGTAACGATTACTGTTGTAGATGTCTTACTGCTACTTGTCATCATCAAGCTGGGTTTCAGGAAGATAGAA
GCTATTGTTGGTGTTTTAGTATTCACGGTCTTATTTATCTTTATGTTTGAAGTATATTTTTCTTCACCTGAATGGAGAGA
CGTGCTGGAAGGATTTCTGCCAAGTACAGCTATCGCTACAAACAGTAACCTGCTATATCTTGCTCTTGGAATCATCGGTG
CAACCATCATGCCCCATAATCTTTATCTGCACTCATCTATCGTGCAGTCTCGGAACTATATACGTGATAATGTTGCTAAG
AAGAAAGAGGCTATTAAGTATGCAGTGATCGATTCACATATTCAGTTGACGATTGCTTTTGTAATCAACTGTCTTATATT
GATACTTGGGGCTTCGTTATTCTATGGCAACGGGGAAGAACTCGGCAGATTCTATGATCTATATAATGCGCTAAAGGCAT
CGACATTCACAGGTGCAGTGGGCGGTGCATTGATGAGTACATTATTCGCTATAGCATTGTTAGCTTCGGGTCAGAAACTC
GACAATTACAGGGACATTATCAGGTCAGATAGTTATGGAAGGGTTCCTTAA

Upstream 100 bases:

>100_bases
GGGGTAACGACAGAGAACAAAAGAATATATTTTATCATTTTGAAAAATTTTTTAGGTTGCCCTAAAGATATGGTATATTA
TTGTATAAGGAGATGATAAT

Downstream 100 bases:

>100_bases
CATAAAGATACCGCAGTGGGCAAGACGACTGATTACAAGGATGATTGCTGTAATTCCTGTCTTCCTATGCTTGTGGTTGT
ATGGTTCAAGTGCAACAAAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MNKSLEEINGKVSFDSEAHGIKKMIMYLGPGLLVAVGYMDPGNWITSMAGGAQFGYTLLFVILLSSLSAMLLQSMCARLG
IASGMDLAQVIKHMSNKPVSIAAWVVTELAIMATDIAEIIGSAIALNLLFNIPLVIGVTITVVDVLLLLVIIKLGFRKIE
AIVGVLVFTVLFIFMFEVYFSSPEWRDVLEGFLPSTAIATNSNLLYLALGIIGATIMPHNLYLHSSIVQSRNYIRDNVAK
KKEAIKYAVIDSHIQLTIAFVINCLILILGASLFYGNGEELGRFYDLYNALKASTFTGAVGGALMSTLFAIALLASGQKL
DNYRDIIRSDSYGRVP

Sequences:

>Translated_336_residues
MNKSLEEINGKVSFDSEAHGIKKMIMYLGPGLLVAVGYMDPGNWITSMAGGAQFGYTLLFVILLSSLSAMLLQSMCARLG
IASGMDLAQVIKHMSNKPVSIAAWVVTELAIMATDIAEIIGSAIALNLLFNIPLVIGVTITVVDVLLLLVIIKLGFRKIE
AIVGVLVFTVLFIFMFEVYFSSPEWRDVLEGFLPSTAIATNSNLLYLALGIIGATIMPHNLYLHSSIVQSRNYIRDNVAK
KKEAIKYAVIDSHIQLTIAFVINCLILILGASLFYGNGEELGRFYDLYNALKASTFTGAVGGALMSTLFAIALLASGQKL
DNYRDIIRSDSYGRVP
>Mature_336_residues
MNKSLEEINGKVSFDSEAHGIKKMIMYLGPGLLVAVGYMDPGNWITSMAGGAQFGYTLLFVILLSSLSAMLLQSMCARLG
IASGMDLAQVIKHMSNKPVSIAAWVVTELAIMATDIAEIIGSAIALNLLFNIPLVIGVTITVVDVLLLLVIIKLGFRKIE
AIVGVLVFTVLFIFMFEVYFSSPEWRDVLEGFLPSTAIATNSNLLYLALGIIGATIMPHNLYLHSSIVQSRNYIRDNVAK
KKEAIKYAVIDSHIQLTIAFVINCLILILGASLFYGNGEELGRFYDLYNALKASTFTGAVGGALMSTLFAIALLASGQKL
DNYRDIIRSDSYGRVP

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=321, Percent_Identity=36.1370716510903, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI295293167, Length=278, Percent_Identity=39.568345323741, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI295293171, Length=278, Percent_Identity=39.568345323741, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI295293169, Length=278, Percent_Identity=39.568345323741, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI295293178, Length=278, Percent_Identity=39.568345323741, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI295293175, Length=278, Percent_Identity=39.568345323741, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI295293173, Length=278, Percent_Identity=39.568345323741, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI10835169, Length=278, Percent_Identity=39.568345323741, Blast_Score=172, Evalue=5e-43,
Organism=Escherichia coli, GI1788736, Length=272, Percent_Identity=35.6617647058824, Blast_Score=161, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI193210616, Length=342, Percent_Identity=33.3333333333333, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI71993856, Length=232, Percent_Identity=37.5, Blast_Score=160, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI17569473, Length=288, Percent_Identity=35.0694444444444, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71999499, Length=325, Percent_Identity=32.6153846153846, Blast_Score=155, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6321841, Length=331, Percent_Identity=39.5770392749245, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6323062, Length=318, Percent_Identity=38.6792452830189, Blast_Score=189, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6324450, Length=341, Percent_Identity=36.6568914956012, Blast_Score=186, Evalue=5e-48,
Organism=Drosophila melanogaster, GI45553443, Length=322, Percent_Identity=34.1614906832298, Blast_Score=188, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24648607, Length=322, Percent_Identity=34.1614906832298, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI281362176, Length=322, Percent_Identity=34.1614906832298, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24648609, Length=322, Percent_Identity=34.1614906832298, Blast_Score=188, Evalue=5e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 36503; Mature: 36503

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSLEEINGKVSFDSEAHGIKKMIMYLGPGLLVAVGYMDPGNWITSMAGGAQFGYTLLF
CCCCHHHCCCCCCCCCHHHHHHHHHHHHCCCHHEEEECCCCCHHHHHHCCCHHHHHHHHH
VILLSSLSAMLLQSMCARLGIASGMDLAQVIKHMSNKPVSIAAWVVTELAIMATDIAEII
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GSAIALNLLFNIPLVIGVTITVVDVLLLLVIIKLGFRKIEAIVGVLVFTVLFIFMFEVYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSPEWRDVLEGFLPSTAIATNSNLLYLALGIIGATIMPHNLYLHSSIVQSRNYIRDNVAK
CCCCHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KKEAIKYAVIDSHIQLTIAFVINCLILILGASLFYGNGEELGRFYDLYNALKASTFTGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GGALMSTLFAIALLASGQKLDNYRDIIRSDSYGRVP
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNKSLEEINGKVSFDSEAHGIKKMIMYLGPGLLVAVGYMDPGNWITSMAGGAQFGYTLLF
CCCCHHHCCCCCCCCCHHHHHHHHHHHHCCCHHEEEECCCCCHHHHHHCCCHHHHHHHHH
VILLSSLSAMLLQSMCARLGIASGMDLAQVIKHMSNKPVSIAAWVVTELAIMATDIAEII
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GSAIALNLLFNIPLVIGVTITVVDVLLLLVIIKLGFRKIEAIVGVLVFTVLFIFMFEVYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSPEWRDVLEGFLPSTAIATNSNLLYLALGIIGATIMPHNLYLHSSIVQSRNYIRDNVAK
CCCCHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KKEAIKYAVIDSHIQLTIAFVINCLILILGASLFYGNGEELGRFYDLYNALKASTFTGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GGALMSTLFAIALLASGQKLDNYRDIIRSDSYGRVP
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA