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The map label for this gene is mro [H]

Identifier: 222150601

GI number: 222150601

Start: 367651

End: 368619

Strand: Direct

Name: mro [H]

Synonym: MCCL_0351

Alternate gene names: 222150601

Gene position: 367651-368619 (Clockwise)

Preceding gene: 222150600

Following gene: 222150603

Centisome position: 17.49

GC content: 32.4

Gene sequence:

>969_bases
TTGAACAATAAAGAATACAAAACCTACACAATTTCCAGTAACAATATAACCATTGAATTAACAAATCTCGGTGCAATCAT
TAAAAGAATCATGGTTCCTCATAATGATCAGGAAATTGATATTGTCCTGGGGTTTGATAATGAACAGGACTACCTCGAAA
ACGATTCAACTTATTTTGGTGCAGTTATTGGTAGAAATGCTAATAGAATAGAGGATAGTATTTTTAACATAGAAGGTACA
CAATTTCATGTTGAATCTAATGAAGGAAACAATAACCTGCATAGTGGTTCAAGCGGTTTTCATACTAGAAAATGGGATGT
TGTATCTCATAATGAATATAGCATCACTTTTTCATTACTTAGTCCGCACTTAGATCAGGGATTTCCCGGGGAATTAAAGA
TGGAAGTAACATACGCACTTACTGAAGATAATGCCTTAGAAGTGACTTACAAAGGTCAAAGTGATAGATTAACTGTGTTT
AATCTAACGAACCATAGTTATTTCAATTTAAATGGGCATGATTCAGGTGACATATTAGATCACAATCTATGGTTGAATAG
TGATAAATATAGTGAATTAAATGATGAGAGTATTCCTACGGGTAAACAGATAGAAGCGACGGATACGAATATGGACTTTA
CAGAAATGAGAAAGATCTCAGAAGATAAGACGGTTGAATATGATGATAATTTTATCTTAAATAGTAATGACATTCATCAG
AAAGCAGCAATACTTATAGGGGATGTTACTGGAATACAAATGGATGTTTATACGAATAGTCCATGTATTCAGCTTTATAC
CGGAAATGGTTTGGATAATGTATATGGTAAAAAGGGTACGGTTTATAACAAACATGCTGGTGTTTGTTTAGAAACTCAAT
TTGAACCGAATAGTATAAATTCAAATCATCCACCGTTAATTGATGGTGAGAAAGAATATAAAACGATTTATAGATTTTCA
GGTTTTTAA

Upstream 100 bases:

>100_bases
AAAATATTTTGTATTTGAGACAAGAGGGTATACATTAGAAGAAATAGAACAGGCACTTGTTACAAATAATACAAAATCTC
TTAATTAAGGTGTGAACACA

Downstream 100 bases:

>100_bases
TAAATGAAAGAAACAAAAAAGTGAGCAATCCATCATCGGATTACTCACTTTTTTATGACTTTTTCAACACGTCATACGCC
CCGGCTGTTACTGCCAGGTC

Product: hypothetical protein

Products: NA

Alternate protein names: Galactose mutarotase; Type-1 mutarotase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MNNKEYKTYTISSNNITIELTNLGAIIKRIMVPHNDQEIDIVLGFDNEQDYLENDSTYFGAVIGRNANRIEDSIFNIEGT
QFHVESNEGNNNLHSGSSGFHTRKWDVVSHNEYSITFSLLSPHLDQGFPGELKMEVTYALTEDNALEVTYKGQSDRLTVF
NLTNHSYFNLNGHDSGDILDHNLWLNSDKYSELNDESIPTGKQIEATDTNMDFTEMRKISEDKTVEYDDNFILNSNDIHQ
KAAILIGDVTGIQMDVYTNSPCIQLYTGNGLDNVYGKKGTVYNKHAGVCLETQFEPNSINSNHPPLIDGEKEYKTIYRFS
GF

Sequences:

>Translated_322_residues
MNNKEYKTYTISSNNITIELTNLGAIIKRIMVPHNDQEIDIVLGFDNEQDYLENDSTYFGAVIGRNANRIEDSIFNIEGT
QFHVESNEGNNNLHSGSSGFHTRKWDVVSHNEYSITFSLLSPHLDQGFPGELKMEVTYALTEDNALEVTYKGQSDRLTVF
NLTNHSYFNLNGHDSGDILDHNLWLNSDKYSELNDESIPTGKQIEATDTNMDFTEMRKISEDKTVEYDDNFILNSNDIHQ
KAAILIGDVTGIQMDVYTNSPCIQLYTGNGLDNVYGKKGTVYNKHAGVCLETQFEPNSINSNHPPLIDGEKEYKTIYRFS
GF
>Mature_322_residues
MNNKEYKTYTISSNNITIELTNLGAIIKRIMVPHNDQEIDIVLGFDNEQDYLENDSTYFGAVIGRNANRIEDSIFNIEGT
QFHVESNEGNNNLHSGSSGFHTRKWDVVSHNEYSITFSLLSPHLDQGFPGELKMEVTYALTEDNALEVTYKGQSDRLTVF
NLTNHSYFNLNGHDSGDILDHNLWLNSDKYSELNDESIPTGKQIEATDTNMDFTEMRKISEDKTVEYDDNFILNSNDIHQ
KAAILIGDVTGIQMDVYTNSPCIQLYTGNGLDNVYGKKGTVYNKHAGVCLETQFEPNSINSNHPPLIDGEKEYKTIYRFS
GF

Specific function: Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose [H]

COG id: COG2017

COG function: function code G; Galactose mutarotase and related enzymes

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldose epimerase family [H]

Homologues:

Organism=Homo sapiens, GI20270355, Length=324, Percent_Identity=37.037037037037, Blast_Score=191, Evalue=7e-49,
Organism=Escherichia coli, GI1786971, Length=314, Percent_Identity=31.8471337579618, Blast_Score=174, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI17557428, Length=299, Percent_Identity=31.7725752508361, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI115533334, Length=299, Percent_Identity=31.7725752508361, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6319493, Length=324, Percent_Identity=29.320987654321, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324399, Length=282, Percent_Identity=31.5602836879433, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6322004, Length=296, Percent_Identity=29.3918918918919, Blast_Score=98, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24668278, Length=328, Percent_Identity=32.9268292682927, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24659048, Length=336, Percent_Identity=34.8214285714286, Blast_Score=177, Evalue=7e-45,
Organism=Drosophila melanogaster, GI24583720, Length=316, Percent_Identity=31.0126582278481, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24668282, Length=333, Percent_Identity=28.5285285285285, Blast_Score=151, Evalue=7e-37,
Organism=Drosophila melanogaster, GI24641876, Length=340, Percent_Identity=27.3529411764706, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018052
- InterPro:   IPR008183
- InterPro:   IPR015443
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.3 [H]

Molecular weight: Translated: 36486; Mature: 36486

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS00545 ALDOSE_1_EPIMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKEYKTYTISSNNITIELTNLGAIIKRIMVPHNDQEIDIVLGFDNEQDYLENDSTYFG
CCCCCEEEEEEECCCEEEEEECHHHHHHHHHCCCCCCEEEEEEECCCCHHHHCCCCEEEE
AVIGRNANRIEDSIFNIEGTQFHVESNEGNNNLHSGSSGFHTRKWDVVSHNEYSITFSLL
EEECCCCCCCCHHEEEECCCEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCEEEEEEEE
SPHLDQGFPGELKMEVTYALTEDNALEVTYKGQSDRLTVFNLTNHSYFNLNGHDSGDILD
CCCCCCCCCCCEEEEEEEEEECCCEEEEEECCCCCCEEEEEECCCEEEEECCCCCCCEEE
HNLWLNSDKYSELNDESIPTGKQIEATDTNMDFTEMRKISEDKTVEYDDNFILNSNDIHQ
CEEEECCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHCCCCCEEEECCCEEECCCCCCC
KAAILIGDVTGIQMDVYTNSPCIQLYTGNGLDNVYGKKGTVYNKHAGVCLETQFEPNSIN
EEEEEEEECCCEEEEEEECCCEEEEEECCCCCCCCCCCCCEEECCCCEEEEEECCCCCCC
SNHPPLIDGEKEYKTIYRFSGF
CCCCCCCCCCHHHEEEEEECCC
>Mature Secondary Structure
MNNKEYKTYTISSNNITIELTNLGAIIKRIMVPHNDQEIDIVLGFDNEQDYLENDSTYFG
CCCCCEEEEEEECCCEEEEEECHHHHHHHHHCCCCCCEEEEEEECCCCHHHHCCCCEEEE
AVIGRNANRIEDSIFNIEGTQFHVESNEGNNNLHSGSSGFHTRKWDVVSHNEYSITFSLL
EEECCCCCCCCHHEEEECCCEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCEEEEEEEE
SPHLDQGFPGELKMEVTYALTEDNALEVTYKGQSDRLTVFNLTNHSYFNLNGHDSGDILD
CCCCCCCCCCCEEEEEEEEEECCCEEEEEECCCCCCEEEEEECCCEEEEECCCCCCCEEE
HNLWLNSDKYSELNDESIPTGKQIEATDTNMDFTEMRKISEDKTVEYDDNFILNSNDIHQ
CEEEECCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHCCCCCEEEECCCEEECCCCCCC
KAAILIGDVTGIQMDVYTNSPCIQLYTGNGLDNVYGKKGTVYNKHAGVCLETQFEPNSIN
EEEEEEEECCCEEEEEEECCCEEEEEECCCCCCCCCCCCCEEECCCCEEEEEECCCCCCC
SNHPPLIDGEKEYKTIYRFSGF
CCCCCCCCCCHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3012466; 3531172 [H]