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The map label for this gene is 222150587

Identifier: 222150587

GI number: 222150587

Start: 353754

End: 355376

Strand: Direct

Name: 222150587

Synonym: MCCL_0337

Alternate gene names: NA

Gene position: 353754-355376 (Clockwise)

Preceding gene: 222150586

Following gene: 222150588

Centisome position: 16.83

GC content: 26.0

Gene sequence:

>1623_bases
ATGAAAATACAAAATATAAATAGCTTTACAGAACTTTCTTTTGTATTAGGTTATAAAACAGGTCATTTAAGAAGGATTTT
ATTTGATATTAATAGTTCTTCCTATACTTCCTTTGAGATTCCTAAGAAGAATGGTGAGGTCAGAAAAATTTATTCTCCAC
ATTCACAGCTTTTATTTTTACAGAAAAAAGTTGCTGCAATATTAGAAAACAGTTTTAATCCTCATTACAAATCTTTTGGA
TTTATAAAAAGAAAAAGTATTGAAAAAAATGCAAAGTTACATTTAAAGAAAAAGTATTTAATAAATATTGATTTAAAAAA
TTTTTTTGAATCAATAACAGCTGGTAGAGTCTACAGTATGTTTGTAAATTATTTTAAATTAGATAGAAATATAGCAGCAA
TACTTACAAATATTTGTTGTCATCCTGATGGTTTTCTACCTCAAGGAGCACCAACTTCTCCTATCATAACGAATATATTA
TGTAAAACTTTAGATAAAGAATTGGATAATTTATCAAAAAGGTACTCTATAACCTATTCTAGATATGCAGATGATATAAC
ATTTTCATCAAATAAGGCTTTTAATTCATATTTTTTAACTCAAGAAGAGTTATTATCAGATGATATAAAAAGAAAAATCG
AGCAAAATGGTTTTTTAATCAATGAAAATAAGTTTCGATACTCAAAGTTTAATCAAAGAAAAGAAGTAACAGGAATAATT
GTTAATGAAAAGTTAAATGTAGATAGGCGATACATAAGAAAGATAAGAGCTATGTTATATTCGATAGAAAATAATTTAGA
TAATTTGGAAGTTCCTAGAACGAAATTTGTTAAAAGTCACTATAAAGGTGATACCATAGAAGATTTATTGAATGTAATAA
AAGGAATGATATCGTATACTACTATGGTAAAAGGGAAAAATAACATTTCTACCAAGTTAGAAATGCGTTTTAATGATATT
TTAGAATGTTTAGAAATTGATTCTGTTAAACCTATTAAAGTAAAGCCACTAGATATAAACGAAGAAAAGGTATGTGTAAT
AAAATTAGAGAAAGTATTTTTTGAAAGTAAAAATAGTGGATTTTATGATATAGATTATGGTCAGGGAACTGGGTTCATAC
TAAAAAATGTAGGTATTGTTTCAAACTATCATGTGTTTGAATTTATTATAGAAGAGTTAGAAAAAGGAAAAAAACCAATA
TGTACAGATAAATATTTTATCAATCTTTATTTCGGAATAAATTGTAGTAAAAAAGTAAAAGCAAAAGTATTAAATTATGA
TAAAGATAAAGATTTGGTAATTTTGCAACCAAAAGATTTAAACATTTTAGAACTGGGATTTGAGTTAGAAGAGGGAACTA
TTGAAAATAACTCGAAAGTAACCTTACTTGGCTATCCTTCTTATAATGAAGGTGATCGTATTAAAGAAGAACAAGGAAAG
TTACTCAGAAAAATAAATGATAAAAAAGATTTTGAAAAATTTGAAATATCGTCTGTAATTCATGCAGGTAATAGTGGCGG
CCCGGTTCTCAATAATAAAGGTAAAGTATTAGGAGTTGCTACAGAAGGAAGAGGAAATGATATTAATAAAGTGGTTCCAA
TAACCAATGTTCTTTCTATGTAG

Upstream 100 bases:

>100_bases
TCGCTATGTATATACTATGTTATTCTATATTATTTTCCGTTTAGAAAATATTGTACTCGAAAACGGTAGAACTTCCCTCT
TTATAAAATAGGAGTGTTTT

Downstream 100 bases:

>100_bases
AAATAAAGAGAATTAATATTAAGCTATTTACAAACTCTACACATCCACTTCACTTTTGCTTAATGTTTGTATTATACGAT
TCAAACATAAAACAAAAGTA

Product: hypothetical protein

Products: NA

Alternate protein names: ORF4-EC67 RT; RNA-directed DNA polymerase; Reverse transcriptase; Ribonuclease H; RNase H [H]

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MKIQNINSFTELSFVLGYKTGHLRRILFDINSSSYTSFEIPKKNGEVRKIYSPHSQLLFLQKKVAAILENSFNPHYKSFG
FIKRKSIEKNAKLHLKKKYLINIDLKNFFESITAGRVYSMFVNYFKLDRNIAAILTNICCHPDGFLPQGAPTSPIITNIL
CKTLDKELDNLSKRYSITYSRYADDITFSSNKAFNSYFLTQEELLSDDIKRKIEQNGFLINENKFRYSKFNQRKEVTGII
VNEKLNVDRRYIRKIRAMLYSIENNLDNLEVPRTKFVKSHYKGDTIEDLLNVIKGMISYTTMVKGKNNISTKLEMRFNDI
LECLEIDSVKPIKVKPLDINEEKVCVIKLEKVFFESKNSGFYDIDYGQGTGFILKNVGIVSNYHVFEFIIEELEKGKKPI
CTDKYFINLYFGINCSKKVKAKVLNYDKDKDLVILQPKDLNILELGFELEEGTIENNSKVTLLGYPSYNEGDRIKEEQGK
LLRKINDKKDFEKFEISSVIHAGNSGGPVLNNKGKVLGVATEGRGNDINKVVPITNVLSM

Sequences:

>Translated_540_residues
MKIQNINSFTELSFVLGYKTGHLRRILFDINSSSYTSFEIPKKNGEVRKIYSPHSQLLFLQKKVAAILENSFNPHYKSFG
FIKRKSIEKNAKLHLKKKYLINIDLKNFFESITAGRVYSMFVNYFKLDRNIAAILTNICCHPDGFLPQGAPTSPIITNIL
CKTLDKELDNLSKRYSITYSRYADDITFSSNKAFNSYFLTQEELLSDDIKRKIEQNGFLINENKFRYSKFNQRKEVTGII
VNEKLNVDRRYIRKIRAMLYSIENNLDNLEVPRTKFVKSHYKGDTIEDLLNVIKGMISYTTMVKGKNNISTKLEMRFNDI
LECLEIDSVKPIKVKPLDINEEKVCVIKLEKVFFESKNSGFYDIDYGQGTGFILKNVGIVSNYHVFEFIIEELEKGKKPI
CTDKYFINLYFGINCSKKVKAKVLNYDKDKDLVILQPKDLNILELGFELEEGTIENNSKVTLLGYPSYNEGDRIKEEQGK
LLRKINDKKDFEKFEISSVIHAGNSGGPVLNNKGKVLGVATEGRGNDINKVVPITNVLSM
>Mature_540_residues
MKIQNINSFTELSFVLGYKTGHLRRILFDINSSSYTSFEIPKKNGEVRKIYSPHSQLLFLQKKVAAILENSFNPHYKSFG
FIKRKSIEKNAKLHLKKKYLINIDLKNFFESITAGRVYSMFVNYFKLDRNIAAILTNICCHPDGFLPQGAPTSPIITNIL
CKTLDKELDNLSKRYSITYSRYADDITFSSNKAFNSYFLTQEELLSDDIKRKIEQNGFLINENKFRYSKFNQRKEVTGII
VNEKLNVDRRYIRKIRAMLYSIENNLDNLEVPRTKFVKSHYKGDTIEDLLNVIKGMISYTTMVKGKNNISTKLEMRFNDI
LECLEIDSVKPIKVKPLDINEEKVCVIKLEKVFFESKNSGFYDIDYGQGTGFILKNVGIVSNYHVFEFIIEELEKGKKPI
CTDKYFINLYFGINCSKKVKAKVLNYDKDKDLVILQPKDLNILELGFELEEGTIENNSKVTLLGYPSYNEGDRIKEEQGK
LLRKINDKKDFEKFEISSVIHAGNSGGPVLNNKGKVLGVATEGRGNDINKVVPITNVLSM

Specific function: Participates in the synthesis of a msDNA (a branched RNA linked by a 2',5'-phosphodiester linkage to a single-stranded DNA) of unknown function. The retron transcript serves as primer and template to the reaction, and codes for the RT [H]

COG id: COG3344

COG function: function code L; Retron-type reverse transcriptase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 reverse transcriptase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000123
- InterPro:   IPR000477 [H]

Pfam domain/function: PF00078 RVT_1 [H]

EC number: =2.7.7.49; =3.1.26.4 [H]

Molecular weight: Translated: 62134; Mature: 62134

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS50878 RT_POL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIQNINSFTELSFVLGYKTGHLRRILFDINSSSYTSFEIPKKNGEVRKIYSPHSQLLFL
CCCCCCCCHHHEEEEEECCCCCEEEEEEEECCCCEEEEECCCCCCCEEEEECCHHHHHHH
QKKVAAILENSFNPHYKSFGFIKRKSIEKNAKLHLKKKYLINIDLKNFFESITAGRVYSM
HHHHHHHHHCCCCCCHHHCCCHHHHCCCCCCEEEEEEEEEEEEEHHHHHHHHHHHHHHHH
FVNYFKLDRNIAAILTNICCHPDGFLPQGAPTSPIITNILCKTLDKELDNLSKRYSITYS
HHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEHH
RYADDITFSSNKAFNSYFLTQEELLSDDIKRKIEQNGFLINENKFRYSKFNQRKEVTGII
HHCCCEEECCCCCCCCEECCHHHHHHHHHHHHHHHCCEEECCCCEEHHHHCCCCCEEEEE
VNEKLNVDRRYIRKIRAMLYSIENNLDNLEVPRTKFVKSHYKGDTIEDLLNVIKGMISYT
EECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHH
TMVKGKNNISTKLEMRFNDILECLEIDSVKPIKVKPLDINEEKVCVIKLEKVFFESKNSG
HEECCCCCCCEEEEEHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEEEHHHCCCCCC
FYDIDYGQGTGFILKNVGIVSNYHVFEFIIEELEKGKKPICTDKYFINLYFGINCSKKVK
EEEEECCCCCCEEEECCCEECCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCHHHH
AKVLNYDKDKDLVILQPKDLNILELGFELEEGTIENNSKVTLLGYPSYNEGDRIKEEQGK
HHHHCCCCCCCEEEECCCCCCEEEECEEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHH
LLRKINDKKDFEKFEISSVIHAGNSGGPVLNNKGKVLGVATEGRGNDINKVVPITNVLSM
HHHHHCCCHHHHHHHHHHHHCCCCCCCCEECCCCCEEEEEECCCCCCCCEEECHHHHHCC
>Mature Secondary Structure
MKIQNINSFTELSFVLGYKTGHLRRILFDINSSSYTSFEIPKKNGEVRKIYSPHSQLLFL
CCCCCCCCHHHEEEEEECCCCCEEEEEEEECCCCEEEEECCCCCCCEEEEECCHHHHHHH
QKKVAAILENSFNPHYKSFGFIKRKSIEKNAKLHLKKKYLINIDLKNFFESITAGRVYSM
HHHHHHHHHCCCCCCHHHCCCHHHHCCCCCCEEEEEEEEEEEEEHHHHHHHHHHHHHHHH
FVNYFKLDRNIAAILTNICCHPDGFLPQGAPTSPIITNILCKTLDKELDNLSKRYSITYS
HHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEHH
RYADDITFSSNKAFNSYFLTQEELLSDDIKRKIEQNGFLINENKFRYSKFNQRKEVTGII
HHCCCEEECCCCCCCCEECCHHHHHHHHHHHHHHHCCEEECCCCEEHHHHCCCCCEEEEE
VNEKLNVDRRYIRKIRAMLYSIENNLDNLEVPRTKFVKSHYKGDTIEDLLNVIKGMISYT
EECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHH
TMVKGKNNISTKLEMRFNDILECLEIDSVKPIKVKPLDINEEKVCVIKLEKVFFESKNSG
HEECCCCCCCEEEEEHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEEEHHHCCCCCC
FYDIDYGQGTGFILKNVGIVSNYHVFEFIIEELEKGKKPICTDKYFINLYFGINCSKKVK
EEEEECCCCCCEEEECCCEECCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCHHHH
AKVLNYDKDKDLVILQPKDLNILELGFELEEGTIENNSKVTLLGYPSYNEGDRIKEEQGK
HHHHCCCCCCCEEEECCCCCCEEEECEEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHH
LLRKINDKKDFEKFEISSVIHAGNSGGPVLNNKGKVLGVATEGRGNDINKVVPITNVLSM
HHHHHCCCHHHHHHHHHHHHCCCCCCCCEECCCCCEEEEEECCCCCCCCEEECHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2466332; 1701261; 1722556 [H]