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The map label for this gene is arg [H]

Identifier: 222150568

GI number: 222150568

Start: 332057

End: 332962

Strand: Direct

Name: arg [H]

Synonym: MCCL_0318

Alternate gene names: 222150568

Gene position: 332057-332962 (Clockwise)

Preceding gene: 222150567

Following gene: 222150569

Centisome position: 15.79

GC content: 38.96

Gene sequence:

>906_bases
ATGAACAAGACAATTGAAATTATTGGTGCGCCAAATGCGTTCGGGCAACGTAAGTTAGGGGTAAATATGGGACCGGATGC
AATGCGTTATGCTGGTTTAGTAGAGCGCATAGAAGCAATTGGACATAAGGTAGTAGACAGTGGAAATATTGAATCACCTG
TAATTGATATGAAAGTGTATAAAAGCGAACAGGACGGTGGTTTAAGAAATTTACCAGAAGTTACTACTTTTTGTGAGACT
TTATGTGAGGCTGTTGATACATCAGTACAAAATGGACATTATCCATTAGTTATTGGTGGTGATCATTCTATTGCGATGGG
TACGATATCAGGGATTGCAAAGCATTATGATAATCTAGGAGTAATCTGGTATGATGCCCATGGTGATCTGAATGTCGCGG
ATTCATCACCTTCTGGCAATATTCACGGAATGCCGTTACGTGCATTAATTGGCGACGGCCATGAAGATTTAGTGAATATC
GGTGGTTATGACAAGAAAGTTAAAGTTGAAAATATTGTCCTTATCGGTATGCGTGATCTTGATGAGGGAGAAAAGTCGTA
TATTAAAGAGGTAGGTATAAAAACCTATACGATGGCAGATATCGATCAGCTCGGTATGAAGACAGTGATCGAACAGACAT
TAGAGCATTTATCAAATTGTGATGGTATTCATTTATCACTTGATGTAGATGCACTGGATCCAAATGAAACACCAGGGACA
GGTACTACAGTTCCAGGTGGTATTACGTATCGCGAAAGTCATCTTGCAATGGAAATGCTAAATGACAGTGACAGAGTGAC
TTCGTTTGAAATCGTAGAAGTGAATCCATTGATAGATATTAATAATCAAACAGCAGAACAAGCGGTAGGACTAACGGGTT
CATTTTTTGGAGAGAAGTTGTTATAA

Upstream 100 bases:

>100_bases
CTGAAATTATTTCTACTATTTTTGTGAGTTTTAATTTTGTGAGTTTTAATTTCGTTGATTTAGATATATTGATATATGAA
TTTTTAAAGGGGAATGAATG

Downstream 100 bases:

>100_bases
GTTGTGCTGTGAATTAAAATATTCAAATACCAGACTTTTAAGGTCTGGTATTTTCTTTTTTTAATATAATTCATATTTTA
AATTATATACTGATTTATAG

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MNKTIEIIGAPNAFGQRKLGVNMGPDAMRYAGLVERIEAIGHKVVDSGNIESPVIDMKVYKSEQDGGLRNLPEVTTFCET
LCEAVDTSVQNGHYPLVIGGDHSIAMGTISGIAKHYDNLGVIWYDAHGDLNVADSSPSGNIHGMPLRALIGDGHEDLVNI
GGYDKKVKVENIVLIGMRDLDEGEKSYIKEVGIKTYTMADIDQLGMKTVIEQTLEHLSNCDGIHLSLDVDALDPNETPGT
GTTVPGGITYRESHLAMEMLNDSDRVTSFEIVEVNPLIDINNQTAEQAVGLTGSFFGEKLL

Sequences:

>Translated_301_residues
MNKTIEIIGAPNAFGQRKLGVNMGPDAMRYAGLVERIEAIGHKVVDSGNIESPVIDMKVYKSEQDGGLRNLPEVTTFCET
LCEAVDTSVQNGHYPLVIGGDHSIAMGTISGIAKHYDNLGVIWYDAHGDLNVADSSPSGNIHGMPLRALIGDGHEDLVNI
GGYDKKVKVENIVLIGMRDLDEGEKSYIKEVGIKTYTMADIDQLGMKTVIEQTLEHLSNCDGIHLSLDVDALDPNETPGT
GTTVPGGITYRESHLAMEMLNDSDRVTSFEIVEVNPLIDINNQTAEQAVGLTGSFFGEKLL
>Mature_301_residues
MNKTIEIIGAPNAFGQRKLGVNMGPDAMRYAGLVERIEAIGHKVVDSGNIESPVIDMKVYKSEQDGGLRNLPEVTTFCET
LCEAVDTSVQNGHYPLVIGGDHSIAMGTISGIAKHYDNLGVIWYDAHGDLNVADSSPSGNIHGMPLRALIGDGHEDLVNI
GGYDKKVKVENIVLIGMRDLDEGEKSYIKEVGIKTYTMADIDQLGMKTVIEQTLEHLSNCDGIHLSLDVDALDPNETPGT
GTTVPGGITYRESHLAMEMLNDSDRVTSFEIVEVNPLIDINNQTAEQAVGLTGSFFGEKLL

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI4502215, Length=309, Percent_Identity=36.2459546925566, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI10947139, Length=305, Percent_Identity=38.6885245901639, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI37537722, Length=229, Percent_Identity=27.9475982532751, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71996843, Length=297, Percent_Identity=30.3030303030303, Blast_Score=132, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6325146, Length=325, Percent_Identity=33.8461538461538, Blast_Score=167, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24638886, Length=312, Percent_Identity=35.2564102564103, Blast_Score=177, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 32525; Mature: 32525

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTIEIIGAPNAFGQRKLGVNMGPDAMRYAGLVERIEAIGHKVVDSGNIESPVIDMKVY
CCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEEEEE
KSEQDGGLRNLPEVTTFCETLCEAVDTSVQNGHYPLVIGGDHSIAMGTISGIAKHYDNLG
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHCCCCEEEEECCCCCEEHHHHHHHHHHHCCCE
VIWYDAHGDLNVADSSPSGNIHGMPLRALIGDGHEDLVNIGGYDKKVKVENIVLIGMRDL
EEEEECCCCEEECCCCCCCCCCCCCHHHHHCCCHHHHEECCCCCCEEEEEEEEEEEECCC
DEGEKSYIKEVGIKTYTMADIDQLGMKTVIEQTLEHLSNCDGIHLSLDVDALDPNETPGT
CCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCC
GTTVPGGITYRESHLAMEMLNDSDRVTSFEIVEVNPLIDINNQTAEQAVGLTGSFFGEKL
CCCCCCCEEEEHHHHHHHHHCCCCCCEEEEEEEECCEEECCCCHHHHHHCCCHHHHHHCC
L
C
>Mature Secondary Structure
MNKTIEIIGAPNAFGQRKLGVNMGPDAMRYAGLVERIEAIGHKVVDSGNIESPVIDMKVY
CCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEEEEE
KSEQDGGLRNLPEVTTFCETLCEAVDTSVQNGHYPLVIGGDHSIAMGTISGIAKHYDNLG
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHCCCCEEEEECCCCCEEHHHHHHHHHHHCCCE
VIWYDAHGDLNVADSSPSGNIHGMPLRALIGDGHEDLVNIGGYDKKVKVENIVLIGMRDL
EEEEECCCCEEECCCCCCCCCCCCCHHHHHCCCHHHHEECCCCCCEEEEEEEEEEEECCC
DEGEKSYIKEVGIKTYTMADIDQLGMKTVIEQTLEHLSNCDGIHLSLDVDALDPNETPGT
CCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCC
GTTVPGGITYRESHLAMEMLNDSDRVTSFEIVEVNPLIDINNQTAEQAVGLTGSFFGEKL
CCCCCCCEEEEHHHHHHHHHCCCCCCEEEEEEEECCEEECCCCHHHHHHCCCHHHHHHCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10332717 [H]