Click here to switch to the map view.

The map label for this gene is moaE [H]

Identifier: 222150400

GI number: 222150400

Start: 154355

End: 154795

Strand: Direct

Name: moaE [H]

Synonym: MCCL_0150

Alternate gene names: 222150400

Gene position: 154355-154795 (Clockwise)

Preceding gene: 222150399

Following gene: 222150401

Centisome position: 7.34

GC content: 40.82

Gene sequence:

>441_bases
GTGAAACAATTTGAAGTAGTAACAATGCCGATTGATGTTGAATATTATCGCAAGATGACGGTAACACCTCATCAAGGTGC
AGTATGTGTATTTACCGGGATCGTCAGAGAATGGACACAAGGTATTAAAACAGAGTATCTGGAGTACGAAGCATACATAC
CGATGGCAGAGAAGAAATTAGAACAAATTGGTCAGGAAATCAACGAGAAATGGCCGGGGACGATTGTAAGTATCGCACAT
CGTATCGGCAATCTTGATGTGTCTGAAATTGCTGTCGTTATTTGTGTTTCAAGCCCACACCGAAAAGATAGTTACGCTGC
AAATGAATATGCAATTGAACGCATCAAAGAGATTGTTCCAATATGGAAAAAAGAAATATGGGAAGACGGAGAACAGTGGA
TCGGTGGCCAAAGAGGTTACCATCCGAATTATAAGGAGTGA

Upstream 100 bases:

>100_bases
GCGTTATCTCAGTTACAAAATATTAAACTGATGGTAGATACATCTGTGGATAGCGAACAAGTGATAAAGGAATTTATACA
AATTTGGGTAGGTGACACAC

Downstream 100 bases:

>100_bases
TATGATGAAAGTATTATATTTTGCACATATTAAAGCGAAGCTGGATCGTACAGAAGATCAGTTTTCGTTTGCTGAGCCTA
TTACAGTAAGTCGGTTTAGA

Product: molybdopterin converting factor subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MKQFEVVTMPIDVEYYRKMTVTPHQGAVCVFTGIVREWTQGIKTEYLEYEAYIPMAEKKLEQIGQEINEKWPGTIVSIAH
RIGNLDVSEIAVVICVSSPHRKDSYAANEYAIERIKEIVPIWKKEIWEDGEQWIGGQRGYHPNYKE

Sequences:

>Translated_146_residues
MKQFEVVTMPIDVEYYRKMTVTPHQGAVCVFTGIVREWTQGIKTEYLEYEAYIPMAEKKLEQIGQEINEKWPGTIVSIAH
RIGNLDVSEIAVVICVSSPHRKDSYAANEYAIERIKEIVPIWKKEIWEDGEQWIGGQRGYHPNYKE
>Mature_146_residues
MKQFEVVTMPIDVEYYRKMTVTPHQGAVCVFTGIVREWTQGIKTEYLEYEAYIPMAEKKLEQIGQEINEKWPGTIVSIAH
RIGNLDVSEIAVVICVSSPHRKDSYAANEYAIERIKEIVPIWKKEIWEDGEQWIGGQRGYHPNYKE

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=130, Percent_Identity=40.7692307692308, Blast_Score=114, Evalue=4e-26,
Organism=Escherichia coli, GI1787003, Length=110, Percent_Identity=35.4545454545455, Blast_Score=77, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17509279, Length=122, Percent_Identity=37.7049180327869, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21356259, Length=145, Percent_Identity=35.8620689655172, Blast_Score=96, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16991; Mature: 16991

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQFEVVTMPIDVEYYRKMTVTPHQGAVCVFTGIVREWTQGIKTEYLEYEAYIPMAEKKL
CCCCEEEEECCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
EQIGQEINEKWPGTIVSIAHRIGNLDVSEIAVVICVSSPHRKDSYAANEYAIERIKEIVP
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
IWKKEIWEDGEQWIGGQRGYHPNYKE
HHHHHHHHCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKQFEVVTMPIDVEYYRKMTVTPHQGAVCVFTGIVREWTQGIKTEYLEYEAYIPMAEKKL
CCCCEEEEECCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
EQIGQEINEKWPGTIVSIAHRIGNLDVSEIAVVICVSSPHRKDSYAANEYAIERIKEIVP
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
IWKKEIWEDGEQWIGGQRGYHPNYKE
HHHHHHHHCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9675851 [H]