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The map label for this gene is fhuD [H]

Identifier: 222150383

GI number: 222150383

Start: 137412

End: 138323

Strand: Direct

Name: fhuD [H]

Synonym: MCCL_0133

Alternate gene names: 222150383

Gene position: 137412-138323 (Clockwise)

Preceding gene: 222150381

Following gene: 222150384

Centisome position: 6.54

GC content: 32.46

Gene sequence:

>912_bases
ATGAAAAAAATATTAATATTATTCATCGCATGTATTATTACGCTCGCAGCATGTGGGAATCAAGATAGCAAGAAAGAGCA
AAAAGAAACAACAGTAGAATTTAAAACAGATAGCGGCAAAACAATAAAAATTCCAAAAGAACCAAAACGTATCGTTGTTA
TGGGTGCAAGCTATGTTGGGAATTTAATTGATTTAGGTGTCACTCCGGTTGGAGCAGATCAATATGCATTCCAATCTGAT
ATATTAAAACCGAAGCTTAAGGGTGTAGAACAGTTAAATCCAGGCGATGTTGAGAAAGTCGCTAAACTAAAACCAGATTT
AATTATTTCATTTGATACGGATAAAGATAATAAGAAGTATGAAAAAATTGCACCAACAATTCCTTTTACATATACAAAGC
ATGGTTATTTAGAAGTACATGAATTATTAGGAAAAATTGTTGGTAAAGAAAAAGAAGCAAAAGCATTTGTGGATAAATGG
AATAAAGAGACGAAAAAAGATGGTAAAGAAATTAAAAAACACCTTGGTGAAGATAAAACTTATTCTATATTCCAGTTCTT
CCAGAAAGAAATCTATGTGTATGGCGATAACTGGGGACGTGGATCAGAAATTATTTATCAAGCATTTGACTTGAAGATGC
AAGATAAAATCGTTAAAGATGTTAAACCGACAGGATGGAAGAAAGTTTCTTCTGAAAGTTTGAGTAGTTATGCAGGAGAC
ATTGTACTCGTGTCAAGTGATGCAGGATCTGCTACAAATACTGTAACTGAATCTAATTTGTGGAAGAACATGGATGCAGT
TAAAAATAACCGCCTCGTTGAATATGATGCTGAAGATTTTTGGTTTAATGATCCAATTTCTTTAGAACATCAAAGAAAAG
TTCTGAAAGACAAGTTGATGAAATTGAAATAA

Upstream 100 bases:

>100_bases
AATTCAATGTAATAAAAGATATAAAAAAATATTGCTTTTATTAATAATTATTCATATAATTAATTGGTAATGATAATCAA
TATCAATTGGAGGCAAAGTA

Downstream 100 bases:

>100_bases
TAAATAGCTGGATATTCCAGCTATTTTTTTATAGCTATTGTTAACTTTTTGTACTAAAAGGTTAACGAATAGTGTAGAAT
AAGTTTATTCTGTTGAAATG

Product: iron compound ABC transporter binding protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein D; Ferrichrome-binding protein; Iron(III)-hydroxamate-binding protein fhuD [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKKILILFIACIITLAACGNQDSKKEQKETTVEFKTDSGKTIKIPKEPKRIVVMGASYVGNLIDLGVTPVGADQYAFQSD
ILKPKLKGVEQLNPGDVEKVAKLKPDLIISFDTDKDNKKYEKIAPTIPFTYTKHGYLEVHELLGKIVGKEKEAKAFVDKW
NKETKKDGKEIKKHLGEDKTYSIFQFFQKEIYVYGDNWGRGSEIIYQAFDLKMQDKIVKDVKPTGWKKVSSESLSSYAGD
IVLVSSDAGSATNTVTESNLWKNMDAVKNNRLVEYDAEDFWFNDPISLEHQRKVLKDKLMKLK

Sequences:

>Translated_303_residues
MKKILILFIACIITLAACGNQDSKKEQKETTVEFKTDSGKTIKIPKEPKRIVVMGASYVGNLIDLGVTPVGADQYAFQSD
ILKPKLKGVEQLNPGDVEKVAKLKPDLIISFDTDKDNKKYEKIAPTIPFTYTKHGYLEVHELLGKIVGKEKEAKAFVDKW
NKETKKDGKEIKKHLGEDKTYSIFQFFQKEIYVYGDNWGRGSEIIYQAFDLKMQDKIVKDVKPTGWKKVSSESLSSYAGD
IVLVSSDAGSATNTVTESNLWKNMDAVKNNRLVEYDAEDFWFNDPISLEHQRKVLKDKLMKLK
>Mature_303_residues
MKKILILFIACIITLAACGNQDSKKEQKETTVEFKTDSGKTIKIPKEPKRIVVMGASYVGNLIDLGVTPVGADQYAFQSD
ILKPKLKGVEQLNPGDVEKVAKLKPDLIISFDTDKDNKKYEKIAPTIPFTYTKHGYLEVHELLGKIVGKEKEAKAFVDKW
NKETKKDGKEIKKHLGEDKTYSIFQFFQKEIYVYGDNWGRGSEIIYQAFDLKMQDKIVKDVKPTGWKKVSSESLSSYAGD
IVLVSSDAGSATNTVTESNLWKNMDAVKNNRLVEYDAEDFWFNDPISLEHQRKVLKDKLMKLK

Specific function: Part of the ABC transporter complex fhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen [H]

COG id: COG0614

COG function: function code P; ABC-type Fe3+-hydroxamate transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 34371; Mature: 34371

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILILFIACIITLAACGNQDSKKEQKETTVEFKTDSGKTIKIPKEPKRIVVMGASYVG
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHCEEEEECCCCCEEECCCCCCEEEEECCHHHH
NLIDLGVTPVGADQYAFQSDILKPKLKGVEQLNPGDVEKVAKLKPDLIISFDTDKDNKKY
HHHHCCCCCCCCCHHHHHHHHCCHHHHCHHCCCCCCHHHHHHCCCCEEEEECCCCCCCHH
EKIAPTIPFTYTKHGYLEVHELLGKIVGKEKEAKAFVDKWNKETKKDGKEIKKHLGEDKT
HHHCCCCCEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCH
YSIFQFFQKEIYVYGDNWGRGSEIIYQAFDLKMQDKIVKDVKPTGWKKVSSESLSSYAGD
HHHHHHHHHEEEEEECCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCC
IVLVSSDAGSATNTVTESNLWKNMDAVKNNRLVEYDAEDFWFNDPISLEHQRKVLKDKLM
EEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHH
KLK
CCC
>Mature Secondary Structure
MKKILILFIACIITLAACGNQDSKKEQKETTVEFKTDSGKTIKIPKEPKRIVVMGASYVG
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHCEEEEECCCCCEEECCCCCCEEEEECCHHHH
NLIDLGVTPVGADQYAFQSDILKPKLKGVEQLNPGDVEKVAKLKPDLIISFDTDKDNKKY
HHHHCCCCCCCCCHHHHHHHHCCHHHHCHHCCCCCCHHHHHHCCCCEEEEECCCCCCCHH
EKIAPTIPFTYTKHGYLEVHELLGKIVGKEKEAKAFVDKWNKETKKDGKEIKKHLGEDKT
HHHCCCCCEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCH
YSIFQFFQKEIYVYGDNWGRGSEIIYQAFDLKMQDKIVKDVKPTGWKKVSSESLSSYAGD
HHHHHHHHHEEEEEECCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCC
IVLVSSDAGSATNTVTESNLWKNMDAVKNNRLVEYDAEDFWFNDPISLEHQRKVLKDKLM
EEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHH
KLK
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8388528; 9639930; 9384377 [H]