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The map label for this gene is ywcA [H]

Identifier: 222150335

GI number: 222150335

Start: 88468

End: 89700

Strand: Direct

Name: ywcA [H]

Synonym: MCCL_0085

Alternate gene names: 222150335

Gene position: 88468-89700 (Clockwise)

Preceding gene: 222150334

Following gene: 222150338

Centisome position: 4.21

GC content: 38.36

Gene sequence:

>1233_bases
ATGATTGCTGCTCGATTTGAACTGAAGAAAGTACGTGCAACGGCTGCAATATCATCGATTACGATTGTTATTTTCTATAT
GCTTGCACAGCTTGTAGGTGCTGGTGCGCTGATTCAGCTCTTATTCAATATACCTTATACATGGGCGGTTATCATCGTTG
GAATTATGATGACAATTTATGTATTATTTGGTGGCATGACAGCAACGAGCTGGGTACAGATGGTTAAAGCAGTGTTATTG
ATGGTTGGAACGATTATTATTTCTTTTCTCGTATTAAAGCACTTTAACTTTAGTATCGCCAACATGTTTGGTGCGATGAA
GTCCATTAATGCACCTGAACTTAAGAGTGACTATATTAATCCGGGGTCACAGGGAAAATCGCCATTAGATAATATCTCTT
TAATCGTTGCTTTATTATTTGGTACAGCAGGATTACCGCATATTCTGATGCGTTTCTTCACGGTAAGTGATGCGAAGACT
GCACGATCATCCGTGATGTGGGCAACATGGATTATTGGGATTTTTTACATACTTACAATATTTTTAGGATTTGGTGCAGC
AAGTTTATTGACACGTGAAGAAATTATTACAGCAAATCCTGCAGGAAATATGGCGGCACCTCTTCTTGCAGATAAATTTG
GTGGAGATATCTTGATGTCATTTGTATGTGCTGTTGCGTTTGCTATAATTCTTGCAGTAGTTGCAGGACTTGTATTATCT
GGTGCTTCTGCTTTTGCACATGATATTTATGGCGAAATCATTAAGAAAGGTAATATATCAGAACGTGAACAGATGAAAGC
AGCAAAAATAGCTTCTTTAGCTGTATCCGTATTATCGATATTACTAGCATTGTTTGCTCAAAATATGAATGTTGCCTTCC
TGGTATCACTTGCTTTTTGTGTGGCAGCAAGTGCAAACTTACCGGTAATTGTATTTACGATTTTCTGGAAGAGGTTTAAT
ACTCAAGGTGCAATCGCTGGACTTTTAACAGGATTAATAACGTCATTAGTGCTTGTAATATTGAGTCCGAATGTAATGAA
TCCTGATGGAACAGCATTTATTACAGCGAATCCCATATTTCCGTTAGCGAACCCTGCAATCATATCTGTGCCTGCAGGAT
TTATCGGAGCGTTCTTAGGAACGTATTTAGGTAAAGCGGAATCTGAAGATAAGTTCAGAGAAGTTGAAGTGAAGTCTGTG
ACAGGTATTGCTCATTCCGAAGTGACACATTAA

Upstream 100 bases:

>100_bases
GGGTTTTTTTATAGTATTGGATATTTAACAGCCTATTTAATTGTAATTATATATTGTTGCAGAACCTTTACGAAACTTAG
GGAAGTATACATTAGCAGAT

Downstream 100 bases:

>100_bases
GCGTAAATTTGGCACCATGCCAATTTCGAGCAAGAAAAAAGAGGGTGAATTTGGCACCATGCCAATTTCACCCTTATACT
TTATCTTTCTTTTACTAATT

Product: sodium-dependent symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MIAARFELKKVRATAAISSITIVIFYMLAQLVGAGALIQLLFNIPYTWAVIIVGIMMTIYVLFGGMTATSWVQMVKAVLL
MVGTIIISFLVLKHFNFSIANMFGAMKSINAPELKSDYINPGSQGKSPLDNISLIVALLFGTAGLPHILMRFFTVSDAKT
ARSSVMWATWIIGIFYILTIFLGFGAASLLTREEIITANPAGNMAAPLLADKFGGDILMSFVCAVAFAIILAVVAGLVLS
GASAFAHDIYGEIIKKGNISEREQMKAAKIASLAVSVLSILLALFAQNMNVAFLVSLAFCVAASANLPVIVFTIFWKRFN
TQGAIAGLLTGLITSLVLVILSPNVMNPDGTAFITANPIFPLANPAIISVPAGFIGAFLGTYLGKAESEDKFREVEVKSV
TGIAHSEVTH

Sequences:

>Translated_410_residues
MIAARFELKKVRATAAISSITIVIFYMLAQLVGAGALIQLLFNIPYTWAVIIVGIMMTIYVLFGGMTATSWVQMVKAVLL
MVGTIIISFLVLKHFNFSIANMFGAMKSINAPELKSDYINPGSQGKSPLDNISLIVALLFGTAGLPHILMRFFTVSDAKT
ARSSVMWATWIIGIFYILTIFLGFGAASLLTREEIITANPAGNMAAPLLADKFGGDILMSFVCAVAFAIILAVVAGLVLS
GASAFAHDIYGEIIKKGNISEREQMKAAKIASLAVSVLSILLALFAQNMNVAFLVSLAFCVAASANLPVIVFTIFWKRFN
TQGAIAGLLTGLITSLVLVILSPNVMNPDGTAFITANPIFPLANPAIISVPAGFIGAFLGTYLGKAESEDKFREVEVKSV
TGIAHSEVTH
>Mature_410_residues
MIAARFELKKVRATAAISSITIVIFYMLAQLVGAGALIQLLFNIPYTWAVIIVGIMMTIYVLFGGMTATSWVQMVKAVLL
MVGTIIISFLVLKHFNFSIANMFGAMKSINAPELKSDYINPGSQGKSPLDNISLIVALLFGTAGLPHILMRFFTVSDAKT
ARSSVMWATWIIGIFYILTIFLGFGAASLLTREEIITANPAGNMAAPLLADKFGGDILMSFVCAVAFAIILAVVAGLVLS
GASAFAHDIYGEIIKKGNISEREQMKAAKIASLAVSVLSILLALFAQNMNVAFLVSLAFCVAASANLPVIVFTIFWKRFN
TQGAIAGLLTGLITSLVLVILSPNVMNPDGTAFITANPIFPLANPAIISVPAGFIGAFLGTYLGKAESEDKFREVEVKSV
TGIAHSEVTH

Specific function: Unknown

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Escherichia coli, GI1790503, Length=416, Percent_Identity=43.75, Blast_Score=325, Evalue=3e-90,
Organism=Escherichia coli, GI87082237, Length=346, Percent_Identity=23.6994219653179, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787251, Length=348, Percent_Identity=24.7126436781609, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 43699; Mature: 43699

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAARFELKKVRATAAISSITIVIFYMLAQLVGAGALIQLLFNIPYTWAVIIVGIMMTIY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHH
VLFGGMTATSWVQMVKAVLLMVGTIIISFLVLKHFNFSIANMFGAMKSINAPELKSDYIN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHCCC
PGSQGKSPLDNISLIVALLFGTAGLPHILMRFFTVSDAKTARSSVMWATWIIGIFYILTI
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
FLGFGAASLLTREEIITANPAGNMAAPLLADKFGGDILMSFVCAVAFAIILAVVAGLVLS
HHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GASAFAHDIYGEIIKKGNISEREQMKAAKIASLAVSVLSILLALFAQNMNVAFLVSLAFC
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VAASANLPVIVFTIFWKRFNTQGAIAGLLTGLITSLVLVILSPNVMNPDGTAFITANPIF
HHCCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCC
PLANPAIISVPAGFIGAFLGTYLGKAESEDKFREVEVKSVTGIAHSEVTH
CCCCCCEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHCCCC
>Mature Secondary Structure
MIAARFELKKVRATAAISSITIVIFYMLAQLVGAGALIQLLFNIPYTWAVIIVGIMMTIY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHH
VLFGGMTATSWVQMVKAVLLMVGTIIISFLVLKHFNFSIANMFGAMKSINAPELKSDYIN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHCCC
PGSQGKSPLDNISLIVALLFGTAGLPHILMRFFTVSDAKTARSSVMWATWIIGIFYILTI
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
FLGFGAASLLTREEIITANPAGNMAAPLLADKFGGDILMSFVCAVAFAIILAVVAGLVLS
HHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GASAFAHDIYGEIIKKGNISEREQMKAAKIASLAVSVLSILLALFAQNMNVAFLVSLAFC
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VAASANLPVIVFTIFWKRFNTQGAIAGLLTGLITSLVLVILSPNVMNPDGTAFITANPIF
HHCCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCC
PLANPAIISVPAGFIGAFLGTYLGKAESEDKFREVEVKSVTGIAHSEVTH
CCCCCCEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]