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The map label for this gene is yhdH [H]

Identifier: 222150327

GI number: 222150327

Start: 79309

End: 80646

Strand: Direct

Name: yhdH [H]

Synonym: MCCL_0077

Alternate gene names: 222150327

Gene position: 79309-80646 (Clockwise)

Preceding gene: 222150326

Following gene: 222150329

Centisome position: 3.77

GC content: 34.75

Gene sequence:

>1338_bases
ATGGAGAGGCAATCAGGTTTCACATCAAAATTAGGTTTTATACTAGCAAGTGCAGGTTCAGCGATAGGTTTGGGAGCGAT
GTGGAAATTCCCTTATGTGATGGCTGATAATGGAGGAGCAGCATTCCTTATTTTGTTTATCATTTTCACTTTATTTATTG
GATTACCAATATTAATGAGTGAATTTGTGATGGGCGTCGCTGGGGAGACTTATAGTACACGAGCATTTAGTAAGTTATCT
GGTAAGAAGAAGTATGATTTAATCGGCTATCTTGGTAATATCGGGGTATTTTTATTAATGAGTTTTTACAGCGTTATCGG
CGGTTTCATCTTAATATATATTATTCGTACGATAAAAGTGATGTTTACTGGAGATGCGACTAAAGATTATACAGTGTTAT
TTGGTAGTATCATATCAAATCCATTGAATACAATTGCAGGGGTTATTTTGTTCCTGGCATTAACGGGCATTATTGTTATT
AAAGGGGTGCAAAATGGTATTGAACGTGTCTCTAAGTTTATGATGCCGATGTTATTTGTAATGTTTCTCATTATGATCAT
TAGGTCCATAACATTACCAAATGCGATGGAAGGTGTATCATTCTTTTTAAATCCAGACTTTAATAAACTAGATCAAGAAG
CCGTTTTATTTGCGTTAGGACAATCGTTCTTCTCTTTATCTGTAGGGTTTGGGGGGATGTTGACTTATGCTTCTTATATG
AAAAAAGGAACTGATCTTGTGCAAGCAGGAGGATATATTGTATTACTTAATATTTTAGTAACGTTATTAGCGGGATTGGC
GATATTTCCAGCCACGGCATCTTTGGGCATAGATAATGCACAAGGCCCAGGTTTACTCTTTATCGTGTTACCTTATGTCT
TTAATCAGCTGCCATTTGGCTCAATATTCTATTTGATTTTCTTGTTGCTGTTTTTCTTTGCAACAATTACGTCATCCATC
AATCTTGTAGAAATCAATGTTTCAAACATGACAAAGAATGATAATACGAAACGTATGAAGTCTGTTCTTGTGATTATTTT
AGGTATCTTCATTGTAAGTATTCCGTGTGCACTATCATTTGGACCGATAAGTGACATGAAGTTCCTAAAAGGAACATTCT
TTGATAATATGGACTTCCTTGTATCCAATATCATGTTGCCAATTGGTGTATTATGCTATACGTTGTTCTCAGGTTACGTA
CTAGACAAAAAGATAATGAAAGCACACTTCGTCCAGAAGCCATATCAGAATAAACTATTTAATGTATGGATTATATTACT
GCGATATGTTATTCCAATCGTCATATTATTTGTAATGATCAATCAATTGATGCAGTAA

Upstream 100 bases:

>100_bases
TCGCTTAAGAGGCCGATGTATGAGCGGTCTCTATACTTAAGAGACCGTGTGTACACACGGTCTCTTTTTTATTTTTATAT
TTATTTTAGGAGGGATTTAT

Downstream 100 bases:

>100_bases
AGGTTTTGCACATTTCATTATGTAAGTTGACCAACGATATAATGTATCACTTCTTCTTGAGCTCTATCGGTGTTTGAATA
TCAGATAGATGAGTCATAAT

Product: sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MERQSGFTSKLGFILASAGSAIGLGAMWKFPYVMADNGGAAFLILFIIFTLFIGLPILMSEFVMGVAGETYSTRAFSKLS
GKKKYDLIGYLGNIGVFLLMSFYSVIGGFILIYIIRTIKVMFTGDATKDYTVLFGSIISNPLNTIAGVILFLALTGIIVI
KGVQNGIERVSKFMMPMLFVMFLIMIIRSITLPNAMEGVSFFLNPDFNKLDQEAVLFALGQSFFSLSVGFGGMLTYASYM
KKGTDLVQAGGYIVLLNILVTLLAGLAIFPATASLGIDNAQGPGLLFIVLPYVFNQLPFGSIFYLIFLLLFFFATITSSI
NLVEINVSNMTKNDNTKRMKSVLVIILGIFIVSIPCALSFGPISDMKFLKGTFFDNMDFLVSNIMLPIGVLCYTLFSGYV
LDKKIMKAHFVQKPYQNKLFNVWIILLRYVIPIVILFVMINQLMQ

Sequences:

>Translated_445_residues
MERQSGFTSKLGFILASAGSAIGLGAMWKFPYVMADNGGAAFLILFIIFTLFIGLPILMSEFVMGVAGETYSTRAFSKLS
GKKKYDLIGYLGNIGVFLLMSFYSVIGGFILIYIIRTIKVMFTGDATKDYTVLFGSIISNPLNTIAGVILFLALTGIIVI
KGVQNGIERVSKFMMPMLFVMFLIMIIRSITLPNAMEGVSFFLNPDFNKLDQEAVLFALGQSFFSLSVGFGGMLTYASYM
KKGTDLVQAGGYIVLLNILVTLLAGLAIFPATASLGIDNAQGPGLLFIVLPYVFNQLPFGSIFYLIFLLLFFFATITSSI
NLVEINVSNMTKNDNTKRMKSVLVIILGIFIVSIPCALSFGPISDMKFLKGTFFDNMDFLVSNIMLPIGVLCYTLFSGYV
LDKKIMKAHFVQKPYQNKLFNVWIILLRYVIPIVILFVMINQLMQ
>Mature_445_residues
MERQSGFTSKLGFILASAGSAIGLGAMWKFPYVMADNGGAAFLILFIIFTLFIGLPILMSEFVMGVAGETYSTRAFSKLS
GKKKYDLIGYLGNIGVFLLMSFYSVIGGFILIYIIRTIKVMFTGDATKDYTVLFGSIISNPLNTIAGVILFLALTGIIVI
KGVQNGIERVSKFMMPMLFVMFLIMIIRSITLPNAMEGVSFFLNPDFNKLDQEAVLFALGQSFFSLSVGFGGMLTYASYM
KKGTDLVQAGGYIVLLNILVTLLAGLAIFPATASLGIDNAQGPGLLFIVLPYVFNQLPFGSIFYLIFLLLFFFATITSSI
NLVEINVSNMTKNDNTKRMKSVLVIILGIFIVSIPCALSFGPISDMKFLKGTFFDNMDFLVSNIMLPIGVLCYTLFSGYV
LDKKIMKAHFVQKPYQNKLFNVWIILLRYVIPIVILFVMINQLMQ

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI21361581, Length=400, Percent_Identity=25.75, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI188528618, Length=371, Percent_Identity=24.7978436657682, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI4507043, Length=421, Percent_Identity=25.6532066508314, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI134304856, Length=353, Percent_Identity=26.3456090651558, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI197276623, Length=352, Percent_Identity=25.8522727272727, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI54607094, Length=352, Percent_Identity=25.8522727272727, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI194018524, Length=301, Percent_Identity=27.5747508305648, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI7657587, Length=376, Percent_Identity=23.4042553191489, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI4507041, Length=421, Percent_Identity=22.8028503562945, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI171184408, Length=411, Percent_Identity=23.6009732360097, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI171184406, Length=411, Percent_Identity=23.6009732360097, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI171184404, Length=411, Percent_Identity=23.6009732360097, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI289191351, Length=492, Percent_Identity=22.7642276422764, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4557046, Length=492, Percent_Identity=22.7642276422764, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI289191377, Length=492, Percent_Identity=22.7642276422764, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI58219014, Length=298, Percent_Identity=23.8255033557047, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI33354281, Length=298, Percent_Identity=24.1610738255034, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI92859670, Length=191, Percent_Identity=31.413612565445, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI5032097, Length=354, Percent_Identity=22.8813559322034, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI300360519, Length=219, Percent_Identity=27.3972602739726, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI218563756, Length=354, Percent_Identity=22.316384180791, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI67782317, Length=168, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI67782313, Length=168, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI67782315, Length=168, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI289191353, Length=274, Percent_Identity=23.7226277372263, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI6005715, Length=211, Percent_Identity=28.436018957346, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI21361693, Length=126, Percent_Identity=29.3650793650794, Blast_Score=66, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17554804, Length=469, Percent_Identity=23.8805970149254, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI25146584, Length=374, Percent_Identity=23.7967914438503, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI71995588, Length=416, Percent_Identity=23.5576923076923, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71998244, Length=359, Percent_Identity=24.7910863509749, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI133952791, Length=201, Percent_Identity=28.3582089552239, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555248, Length=164, Percent_Identity=26.219512195122, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI212642127, Length=322, Percent_Identity=23.2919254658385, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19921936, Length=411, Percent_Identity=26.0340632603406, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17136952, Length=379, Percent_Identity=23.7467018469657, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI281364394, Length=377, Percent_Identity=23.8726790450928, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI28574704, Length=377, Percent_Identity=23.8726790450928, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI17136950, Length=377, Percent_Identity=23.8726790450928, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI28574702, Length=377, Percent_Identity=23.8726790450928, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI281365034, Length=418, Percent_Identity=24.4019138755981, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24762620, Length=420, Percent_Identity=27.1428571428571, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI19921352, Length=424, Percent_Identity=24.7641509433962, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24584353, Length=424, Percent_Identity=24.7641509433962, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24661428, Length=380, Percent_Identity=24.7368421052632, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI221329674, Length=386, Percent_Identity=24.8704663212435, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24639514, Length=392, Percent_Identity=24.7448979591837, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI45551088, Length=394, Percent_Identity=24.8730964467005, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24652942, Length=394, Percent_Identity=24.8730964467005, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24639516, Length=412, Percent_Identity=23.7864077669903, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24582567, Length=488, Percent_Identity=25.2049180327869, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281364136, Length=215, Percent_Identity=30.6976744186047, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45550877, Length=235, Percent_Identity=26.3829787234043, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24654186, Length=176, Percent_Identity=28.9772727272727, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI45551183, Length=235, Percent_Identity=26.3829787234043, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582569, Length=164, Percent_Identity=28.6585365853659, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI281363702, Length=178, Percent_Identity=26.4044943820225, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 49169; Mature: 49169

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]