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The map label for this gene is yfmJ [H]

Identifier: 222150298

GI number: 222150298

Start: 50706

End: 51707

Strand: Direct

Name: yfmJ [H]

Synonym: MCCL_0048

Alternate gene names: 222150298

Gene position: 50706-51707 (Clockwise)

Preceding gene: 222150297

Following gene: 222150299

Centisome position: 2.41

GC content: 38.02

Gene sequence:

>1002_bases
ATGAATAATGAACAAATTGTACTTGCTAAACGTCCTGAAGGATTACCACAAGCTGATGTATTTCGATATGAACCGATTGA
GATAACAGCGCCTGAAGAGGGTGAAGTACAAGTGGAATCTATCTATATTTCAGTTGATCCTTATATGAGAGGACGAATGA
ATGATACAAAGAGTTATGTTCAACCTTATGAAATCGATGCCCCGATTCATGGACATATCGTCGGAAAAATTATTGAGTCA
AATCATGCGCAATATAAAAGCGGAGATTATATAACAGGGATATTACCTTGGAAGAAAGTGAATACGATTAGTGCAGACAA
AGTAACAAAAGTTGCTTCTGAATCTGTACCTTTGTACTTATACTTAAGCGTATTAGGTATGCCTGGTATGACGGCCTATA
CAGGACTATTGCAAATAGGAAAGCCACAAGAAGGTGAAACCGTAGTTGTTTCTGCCGCTTCAGGTGCTGTGGGTTCAGTT
GTAGGACAAATTGCCAAGATTAAAGGTGCACGAGTTGTGGGTATTGCAGGTGGAGAAAAGAAAACCTCGTATTTAAAAGA
TGTGCTAGGTTTTGATGCTGTAATAGATTACAAAAGAGAAGATTTTGCACAGCAACTAAAATCTGCAGTACCAGACGGTA
TAGATGTGTATTTTGAAAATGTTGGTGGAGAAGTATCAGACGAAGTTTTCAAATATTTAAATAAATTTGCTAGAATTCCT
GTCTGCGGTGCAATTTCAACGTACAATAGTAAAGAAGATATTGGACCAAGAATCCAAGGCACTTTAGTAAAAAGTCAGGC
ACTTATGCAAGGGTTTGTAGTAGCGCAGTTTGCAGAACACTTTAAAGAAGCGAGTGAACAATTAGCGCAATGGGTAGCAG
AAGGTAAGATTAAATCAGAAGTAACGATTGATGAAGGATTTGATCAGCTGCCATCAGCCTTCAGAAAGCTATTTACAGGA
GAAAACTTTGGGAAACAAATTGTCAAGGTGGCAGAAGAATAA

Upstream 100 bases:

>100_bases
AGTATTAACAGATACTAGACTCAAAGGTCGAGAGTTCCAGGTAATCAATGGGGAATTAAATCTAGATGATGCAGTCATCA
AATACTTGGGGGAATAATAA

Downstream 100 bases:

>100_bases
AGGAAAGACATGAGAATATTAATATAGAAATTATGTTCAGTACAAAGGATATTAGTTAATCATGTAAAGATTACAGTAAT
TACTTTAACTGAATATATGA

Product: quinone oxidoreductase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MNNEQIVLAKRPEGLPQADVFRYEPIEITAPEEGEVQVESIYISVDPYMRGRMNDTKSYVQPYEIDAPIHGHIVGKIIES
NHAQYKSGDYITGILPWKKVNTISADKVTKVASESVPLYLYLSVLGMPGMTAYTGLLQIGKPQEGETVVVSAASGAVGSV
VGQIAKIKGARVVGIAGGEKKTSYLKDVLGFDAVIDYKREDFAQQLKSAVPDGIDVYFENVGGEVSDEVFKYLNKFARIP
VCGAISTYNSKEDIGPRIQGTLVKSQALMQGFVVAQFAEHFKEASEQLAQWVAEGKIKSEVTIDEGFDQLPSAFRKLFTG
ENFGKQIVKVAEE

Sequences:

>Translated_333_residues
MNNEQIVLAKRPEGLPQADVFRYEPIEITAPEEGEVQVESIYISVDPYMRGRMNDTKSYVQPYEIDAPIHGHIVGKIIES
NHAQYKSGDYITGILPWKKVNTISADKVTKVASESVPLYLYLSVLGMPGMTAYTGLLQIGKPQEGETVVVSAASGAVGSV
VGQIAKIKGARVVGIAGGEKKTSYLKDVLGFDAVIDYKREDFAQQLKSAVPDGIDVYFENVGGEVSDEVFKYLNKFARIP
VCGAISTYNSKEDIGPRIQGTLVKSQALMQGFVVAQFAEHFKEASEQLAQWVAEGKIKSEVTIDEGFDQLPSAFRKLFTG
ENFGKQIVKVAEE
>Mature_333_residues
MNNEQIVLAKRPEGLPQADVFRYEPIEITAPEEGEVQVESIYISVDPYMRGRMNDTKSYVQPYEIDAPIHGHIVGKIIES
NHAQYKSGDYITGILPWKKVNTISADKVTKVASESVPLYLYLSVLGMPGMTAYTGLLQIGKPQEGETVVVSAASGAVGSV
VGQIAKIKGARVVGIAGGEKKTSYLKDVLGFDAVIDYKREDFAQQLKSAVPDGIDVYFENVGGEVSDEVFKYLNKFARIP
VCGAISTYNSKEDIGPRIQGTLVKSQALMQGFVVAQFAEHFKEASEQLAQWVAEGKIKSEVTIDEGFDQLPSAFRKLFTG
ENFGKQIVKVAEE

Specific function: Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds (Potential) [H]

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226246682, Length=347, Percent_Identity=39.4812680115274, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI226246680, Length=347, Percent_Identity=39.4812680115274, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI22748929, Length=347, Percent_Identity=39.4812680115274, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI226059159, Length=328, Percent_Identity=41.7682926829268, Blast_Score=225, Evalue=5e-59,
Organism=Homo sapiens, GI226059133, Length=328, Percent_Identity=41.7682926829268, Blast_Score=225, Evalue=5e-59,
Organism=Homo sapiens, GI226056130, Length=299, Percent_Identity=40.8026755852843, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI28557745, Length=318, Percent_Identity=30.8176100628931, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI47519420, Length=215, Percent_Identity=28.3720930232558, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI226510941, Length=336, Percent_Identity=45.5357142857143, Blast_Score=314, Evalue=6e-87,
Organism=Escherichia coli, GI1790485, Length=282, Percent_Identity=27.3049645390071, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI133901712, Length=355, Percent_Identity=32.6760563380282, Blast_Score=193, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI133901710, Length=355, Percent_Identity=32.6760563380282, Blast_Score=193, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6323504, Length=326, Percent_Identity=31.5950920245399, Blast_Score=129, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 36455; Mature: 36455

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNEQIVLAKRPEGLPQADVFRYEPIEITAPEEGEVQVESIYISVDPYMRGRMNDTKSYV
CCCCEEEEEECCCCCCCCCCEEECCEEEECCCCCCEEEEEEEEEECCHHCCCCCCHHHHC
QPYEIDAPIHGHIVGKIIESNHAQYKSGDYITGILPWKKVNTISADKVTKVASESVPLYL
CCEECCCCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCEE
YLSVLGMPGMTAYTGLLQIGKPQEGETVVVSAASGAVGSVVGQIAKIKGARVVGIAGGEK
EEHHHCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCH
KTSYLKDVLGFDAVIDYKREDFAQQLKSAVPDGIDVYFENVGGEVSDEVFKYLNKFARIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHCCCCHHHHHHHHHHHHHCCC
VCGAISTYNSKEDIGPRIQGTLVKSQALMQGFVVAQFAEHFKEASEQLAQWVAEGKIKSE
CEEECCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VTIDEGFDQLPSAFRKLFTGENFGKQIVKVAEE
EEHHCCHHHHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MNNEQIVLAKRPEGLPQADVFRYEPIEITAPEEGEVQVESIYISVDPYMRGRMNDTKSYV
CCCCEEEEEECCCCCCCCCCEEECCEEEECCCCCCEEEEEEEEEECCHHCCCCCCHHHHC
QPYEIDAPIHGHIVGKIIESNHAQYKSGDYITGILPWKKVNTISADKVTKVASESVPLYL
CCEECCCCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCEE
YLSVLGMPGMTAYTGLLQIGKPQEGETVVVSAASGAVGSVVGQIAKIKGARVVGIAGGEK
EEHHHCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCH
KTSYLKDVLGFDAVIDYKREDFAQQLKSAVPDGIDVYFENVGGEVSDEVFKYLNKFARIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHCCCCHHHHHHHHHHHHHCCC
VCGAISTYNSKEDIGPRIQGTLVKSQALMQGFVVAQFAEHFKEASEQLAQWVAEGKIKSE
CEEECCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VTIDEGFDQLPSAFRKLFTGENFGKQIVKVAEE
EEHHCCHHHHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]