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The map label for this gene is dsbC [H]

Identifier: 222150256

GI number: 222150256

Start: 6012

End: 6428

Strand: Direct

Name: dsbC [H]

Synonym: MCCL_0006

Alternate gene names: 222150256

Gene position: 6012-6428 (Clockwise)

Preceding gene: 222150255

Following gene: 222150257

Centisome position: 0.29

GC content: 32.13

Gene sequence:

>417_bases
ATGAAAAATACTAAATACTTCTATATTTCCTGGGTAATTGCACTTGTCGCCACATTGGGAAGTCTGTACTTTTCTCAAAT
ACGTCATTTTATTCCTTGTGAGATGTGCTGGTATCAGAGGATACTCATGTATCCTATAGTGATTATTGCAGGGTTTGCAG
TATTTAATCACACTTATCATTATAAATATTTAATAATGACTTTCTCTATCATAGGTTTTTGTTTCTCATGCTATCATTAT
ATGGAGCAGAAGATACCAGGATTTGCAGAGGTTAAACCTTGTGTCGGAGGAGTACCTTGTAGTGCTCAGTATATTAATTA
TTTTGGATTTATCACAATTCCTTTTTTAGCGGGCGTTGCATTTCTATTAATTACAATAACTATGTTGTGTGTAAAAAAAG
AAAATTATGCAAATTAA

Upstream 100 bases:

>100_bases
ATGTGACAATGACACCGACGATCATTGTAAACGGAAAAGAAGTTAAAAATCCAATGGATCCTGCTGAAGTGGACAAAGTA
ATCGATGAGGCAGTTAAACA

Downstream 100 bases:

>100_bases
ACTTTAATAATTATGACTTATGTGTTAAAGCGTTGGAATATCTTATTCCCACGCTTTTTATTCGTTTAAAAAACATGCAT
TTTTTGTGAATTAACGGTAT

Product: thiol-disulfide oxidoreductase DsbC

Products: NA

Alternate protein names: Disulfide oxidoreductase C; Thiol-disulfide oxidoreductase C [H]

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MKNTKYFYISWVIALVATLGSLYFSQIRHFIPCEMCWYQRILMYPIVIIAGFAVFNHTYHYKYLIMTFSIIGFCFSCYHY
MEQKIPGFAEVKPCVGGVPCSAQYINYFGFITIPFLAGVAFLLITITMLCVKKENYAN

Sequences:

>Translated_138_residues
MKNTKYFYISWVIALVATLGSLYFSQIRHFIPCEMCWYQRILMYPIVIIAGFAVFNHTYHYKYLIMTFSIIGFCFSCYHY
MEQKIPGFAEVKPCVGGVPCSAQYINYFGFITIPFLAGVAFLLITITMLCVKKENYAN
>Mature_138_residues
MKNTKYFYISWVIALVATLGSLYFSQIRHFIPCEMCWYQRILMYPIVIIAGFAVFNHTYHYKYLIMTFSIIGFCFSCYHY
MEQKIPGFAEVKPCVGGVPCSAQYINYFGFITIPFLAGVAFLLITITMLCVKKENYAN

Specific function: Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. Not normally required for production of the secreted lantibiotic sublancin 168, although it can partially substitute for BdbB when the

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family. BdbC subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003752
- InterPro:   IPR012187 [H]

Pfam domain/function: PF02600 DsbB [H]

EC number: NA

Molecular weight: Translated: 16035; Mature: 16035

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
9.4 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
9.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNTKYFYISWVIALVATLGSLYFSQIRHFIPCEMCWYQRILMYPIVIIAGFAVFNHTYH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKYLIMTFSIIGFCFSCYHYMEQKIPGFAEVKPCVGGVPCSAQYINYFGFITIPFLAGVA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FLLITITMLCVKKENYAN
HHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKNTKYFYISWVIALVATLGSLYFSQIRHFIPCEMCWYQRILMYPIVIIAGFAVFNHTYH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKYLIMTFSIIGFCFSCYHYMEQKIPGFAEVKPCVGGVPCSAQYINYFGFITIPFLAGVA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FLLITITMLCVKKENYAN
HHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 10455116; 11844773; 11744713; 11872755 [H]