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The map label for this gene is dsbD [H]

Identifier: 222150255

GI number: 222150255

Start: 5308

End: 6015

Strand: Direct

Name: dsbD [H]

Synonym: MCCL_0005

Alternate gene names: 222150255

Gene position: 5308-6015 (Clockwise)

Preceding gene: 222150254

Following gene: 222150256

Centisome position: 0.25

GC content: 34.6

Gene sequence:

>708_bases
ATGAAAAATAAAGGATCACTAATTTTTACGATGATAATGACCCTACTTGTTATTGGTGTCATTGCTGCATTGATTATTTC
AAATCAAAATAAGAAAGAAAGTTCCGTAGATACTGAATCATTAGGTACTGCAAATACGAACAATCAGCAAGGATTAAAAC
TATTAGATCAAATCGATATTAAAGATCAACCAATGATTGGTAAAGATGAAGCAAAGGTTACCATCATAGAATTTGGAGAT
TTTAAATGTCCGGCATGTAAGGTGTTCGAATTAGATATCAAACCTGACTTGAAAAAGAAATATATAGATAGCGGAAAAGC
TAAGTTGTATTTCATTAATACCCCATTTCATGGTGAAGGATCGATGCTTGGGAGTCTGGCCGCGGAAACATTGATTAAAC
AAGAACCTGACAAGTATAGTGCATTTCAACAAGCATTGTTCGAAATGCAACCTGATACAGAAGAAGAATGGTTGACGATT
GATGCTGTTAAGAAAGCAGCAAAAACTGCCGCTGTCAGTAATATAGACAAACTTGTAAAGGATGTTGAAGCTTTAAAAGA
AAAAGCAGCAGTTAAAAAGGATATCAATCTCGTTGAAAAACATAATGTGACAATGACACCGACGATCATTGTAAACGGAA
AAGAAGTTAAAAATCCAATGGATCCTGCTGAAGTGGACAAAGTAATCGATGAGGCAGTTAAACAATGA

Upstream 100 bases:

>100_bases
AAACTAAATAATGTCACAAAATCGTAATGATTATACACGTGCAAAATTTGATTAATTAATATAAAATTTATACTATCAAT
TAATTGTATAGGAGATAGTT

Downstream 100 bases:

>100_bases
AAAATACTAAATACTTCTATATTTCCTGGGTAATTGCACTTGTCGCCACATTGGGAAGTCTGTACTTTTCTCAAATACGT
CATTTTATTCCTTGTGAGAT

Product: thiol-disulfide oxidoreductase

Products: NA

Alternate protein names: Disulfide oxidoreductase D; Thiol-disulfide oxidoreductase D [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MKNKGSLIFTMIMTLLVIGVIAALIISNQNKKESSVDTESLGTANTNNQQGLKLLDQIDIKDQPMIGKDEAKVTIIEFGD
FKCPACKVFELDIKPDLKKKYIDSGKAKLYFINTPFHGEGSMLGSLAAETLIKQEPDKYSAFQQALFEMQPDTEEEWLTI
DAVKKAAKTAAVSNIDKLVKDVEALKEKAAVKKDINLVEKHNVTMTPTIIVNGKEVKNPMDPAEVDKVIDEAVKQ

Sequences:

>Translated_235_residues
MKNKGSLIFTMIMTLLVIGVIAALIISNQNKKESSVDTESLGTANTNNQQGLKLLDQIDIKDQPMIGKDEAKVTIIEFGD
FKCPACKVFELDIKPDLKKKYIDSGKAKLYFINTPFHGEGSMLGSLAAETLIKQEPDKYSAFQQALFEMQPDTEEEWLTI
DAVKKAAKTAAVSNIDKLVKDVEALKEKAAVKKDINLVEKHNVTMTPTIIVNGKEVKNPMDPAEVDKVIDEAVKQ
>Mature_235_residues
MKNKGSLIFTMIMTLLVIGVIAALIISNQNKKESSVDTESLGTANTNNQQGLKLLDQIDIKDQPMIGKDEAKVTIIEFGD
FKCPACKVFELDIKPDLKKKYIDSGKAKLYFINTPFHGEGSMLGSLAAETLIKQEPDKYSAFQQALFEMQPDTEEEWLTI
DAVKKAAKTAAVSNIDKLVKDVEALKEKAAVKKDINLVEKHNVTMTPTIIVNGKEVKNPMDPAEVDKVIDEAVKQ

Specific function: Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. May be required for the stability of secreted proteins with disulfide bonds. Not required for sporulation [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25970; Mature: 25970

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKGSLIFTMIMTLLVIGVIAALIISNQNKKESSVDTESLGTANTNNQQGLKLLDQIDI
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHCCC
KDQPMIGKDEAKVTIIEFGDFKCPACKVFELDIKPDLKKKYIDSGKAKLYFINTPFHGEG
CCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCHHHHHHCCCCEEEEEEECCCCCCC
SMLGSLAAETLIKQEPDKYSAFQQALFEMQPDTEEEWLTIDAVKKAAKTAAVSNIDKLVK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHH
DVEALKEKAAVKKDINLVEKHNVTMTPTIIVNGKEVKNPMDPAEVDKVIDEAVKQ
HHHHHHHHHHHHHHHHHHHHCCCEECCEEEECCHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNKGSLIFTMIMTLLVIGVIAALIISNQNKKESSVDTESLGTANTNNQQGLKLLDQIDI
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHCCC
KDQPMIGKDEAKVTIIEFGDFKCPACKVFELDIKPDLKKKYIDSGKAKLYFINTPFHGEG
CCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCHHHHHHCCCCEEEEEEECCCCCCC
SMLGSLAAETLIKQEPDKYSAFQQALFEMQPDTEEEWLTIDAVKKAAKTAAVSNIDKLVK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHH
DVEALKEKAAVKKDINLVEKHNVTMTPTIIVNGKEVKNPMDPAEVDKVIDEAVKQ
HHHHHHHHHHHHHHHHHHHHCCCEECCEEEECCHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11844773; 11744713 [H]