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The map label for this gene is iscR [H]

Identifier: 222111232

GI number: 222111232

Start: 2179514

End: 2180077

Strand: Direct

Name: iscR [H]

Synonym: Dtpsy_2040

Alternate gene names: 222111232

Gene position: 2179514-2180077 (Clockwise)

Preceding gene: 222111231

Following gene: 222111235

Centisome position: 57.41

GC content: 65.25

Gene sequence:

>564_bases
ATGCGTTTGACCACCCGAGGCAAACTCGCCGTCACTGCGGTCACCGATCTGGCCTTGCGCTCCCACGGCCGGCCCATCGC
GCTTCCCTCCATCAGCGCCCGCCAAGGCATCTCCCTTTCGTATCTCGAAGACATCTTCAGCGCACTGCGCCGCGCCGGCC
TGGTCCACAGCATTCGCGGGCCCGGCGGGGGGTACACACTGACACGGCCGCCACAGGAACTCTCTGTGGCCGATATCGTC
ATCGCCTCCGAAAAATACATGGGCGGCGCCGATGACAAGGGCACGGACACCGGCATCGCATCGGCACCAGGCGAGATGAC
GGCCGAGCTGTGGGCCAACTTCCACTCGCGTGTCATGGAATACCTGCAGTCCATTACGGTGGCGGACCTGCTGACCCAAC
GGGAAGCCAGCGCCTGCCATGCCGACCATTCTGCAGCCGTGGTAGTGGCCCCGCCCGCCAGCACCACAGGCCGACGGGCA
GCGAAAACCCAGCTACCGTCAGGGGATGTGCCGAACTCCGTATTTGCCTTGGGGCTTGCCGTTCCGCGCACCCGGACGAG
TTGA

Upstream 100 bases:

>100_bases
GTGCGCCGCGCAACTCCGGCGTGCAACCCCCTTCCTCTTTTCCTTCCTGACCATCGGACCGATGGCTTCAGGCCCTTTTC
CTACCCTCAGGAACAGCACC

Downstream 100 bases:

>100_bases
TGCGCCGGCATCCGTAGCGTCCTTCTCCGGAACGACACGGATGCCCGCCCTGGGCGACGACACCGCCGACTATTTGCCGA
GCAGGACCTTCAATGCGCTC

Product: BadM/Rrf2 family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MRLTTRGKLAVTAVTDLALRSHGRPIALPSISARQGISLSYLEDIFSALRRAGLVHSIRGPGGGYTLTRPPQELSVADIV
IASEKYMGGADDKGTDTGIASAPGEMTAELWANFHSRVMEYLQSITVADLLTQREASACHADHSAAVVVAPPASTTGRRA
AKTQLPSGDVPNSVFALGLAVPRTRTS

Sequences:

>Translated_187_residues
MRLTTRGKLAVTAVTDLALRSHGRPIALPSISARQGISLSYLEDIFSALRRAGLVHSIRGPGGGYTLTRPPQELSVADIV
IASEKYMGGADDKGTDTGIASAPGEMTAELWANFHSRVMEYLQSITVADLLTQREASACHADHSAAVVVAPPASTTGRRA
AKTQLPSGDVPNSVFALGLAVPRTRTS
>Mature_187_residues
MRLTTRGKLAVTAVTDLALRSHGRPIALPSISARQGISLSYLEDIFSALRRAGLVHSIRGPGGGYTLTRPPQELSVADIV
IASEKYMGGADDKGTDTGIASAPGEMTAELWANFHSRVMEYLQSITVADLLTQREASACHADHSAAVVVAPPASTTGRRA
AKTQLPSGDVPNSVFALGLAVPRTRTS

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=135, Percent_Identity=41.4814814814815, Blast_Score=105, Evalue=2e-24,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 19635; Mature: 19635

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTTRGKLAVTAVTDLALRSHGRPIALPSISARQGISLSYLEDIFSALRRAGLVHSIRG
CCCCCCCCEEEHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCC
PGGGYTLTRPPQELSVADIVIASEKYMGGADDKGTDTGIASAPGEMTAELWANFHSRVME
CCCCCCCCCCCHHCCHHHEEEECHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YLQSITVADLLTQREASACHADHSAAVVVAPPASTTGRRAAKTQLPSGDVPNSVFALGLA
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHCCCCCCCCCHHHHHHHHC
VPRTRTS
CCCCCCC
>Mature Secondary Structure
MRLTTRGKLAVTAVTDLALRSHGRPIALPSISARQGISLSYLEDIFSALRRAGLVHSIRG
CCCCCCCCEEEHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCC
PGGGYTLTRPPQELSVADIVIASEKYMGGADDKGTDTGIASAPGEMTAELWANFHSRVME
CCCCCCCCCCCHHCCHHHEEEECHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YLQSITVADLLTQREASACHADHSAAVVVAPPASTTGRRAAKTQLPSGDVPNSVFALGLA
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHCCCCCCCCCHHHHHHHHC
VPRTRTS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA