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The map label for this gene is ptxB [H]

Identifier: 222111204

GI number: 222111204

Start: 2150224

End: 2151114

Strand: Direct

Name: ptxB [H]

Synonym: Dtpsy_2012

Alternate gene names: 222111204

Gene position: 2150224-2151114 (Clockwise)

Preceding gene: 222111203

Following gene: 222111205

Centisome position: 56.64

GC content: 67.23

Gene sequence:

>891_bases
ATGACCTCTTCAACGACCGCACGCCGTGCGGCGCTGCGCCGCTTTGCCGCAGCCGCCGCCGCTGTCGCCAGCTTCTCTCC
CCTCCTGTCCACCCAGGCCGCCGAGCCGCAGGTGCTGCGCGTATCCGCCATCCCCGACGAAGCGCCTACCGAACTGCAAC
GCAAGTTCAAGCCGCTGGGCGAATACCTGTCGCAGGCCACCGGAATGAAGGTGGTGTTCACCCCGGTAACCGACTACGCC
GCCGTGGTCGAATCCCTGGCCACGCGCAAGCTGGACCTGGCCTGGCTGGGCGGCTTCACCTACGTGCAGGCGCGCATCCG
CACGGGTGGTACGGCCATTCCGCTGGTGCAGCGGGAGGAGGACGCACGCTTTACCTCGCGCTTCATCACCGCCGACCCCA
CCATCCAGGGCCTGGCCGACCTCAAGGGCAAGACCTTTGCCTTTGGCGCTCCCTCGTCCACCTCGGGCAGCCTGATGCCG
CGCTACTTCCTGCAGCAAGCCGGCGTCCAGCCAGAGCGGGATTTCAAGACCGTGGCCTATTCCGGCGCGCATGACGCGAC
CGTGGCCTTCGTGGCCGCTGGCAAGGCGCAGGCCGGCGTGCTCAACGCCTCCGTCTGGGACAAGCTGGTCGAGACCAAGA
AGGTGGATCCGTCCAAGGTACGGGTGTTCGCCACCACCCCACCCTACTTCGACTACAACTGGACCGTGCGCGGCGATCTC
GATCCCGCCGTGGTGCAGAAGATCAAGGCCGCCTTCCTGGCGCTCGACCCCGCCAAGCCCGAGCACAAGGCCATCCTGGA
ACTGCAGCGCGCCTCGCGCTTCATCGCCACCGAGCCGCGCAACTACGACGGCATCGAAGACGCCGCCAAGACGGCCGGCC
TGCTGAAGTAA

Upstream 100 bases:

>100_bases
CCGGGCAGCCGGCGCCACCTTGGGCGACAATGGCGGCCCTCGCGCACACCCCGCAGGCCCTCGGCTTGCAGCGCGCTCGA
TTCAACTTTCCCGCACCGCC

Downstream 100 bases:

>100_bases
GCGCGCCGGCGCGCGCGGGCCTGGCCCAGGTAGCCCGCGCGTGCACCATTGGCGTTTTTGATCAAATCAGCCCCTAGCGC
TTGCTGGATAAGCGCTAGCA

Product: phosphonate ABC transporter periplasmic phosphonate-binding protein

Products: 3-phospho-serine [Cytoplasm]; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MTSSTTARRAALRRFAAAAAAVASFSPLLSTQAAEPQVLRVSAIPDEAPTELQRKFKPLGEYLSQATGMKVVFTPVTDYA
AVVESLATRKLDLAWLGGFTYVQARIRTGGTAIPLVQREEDARFTSRFITADPTIQGLADLKGKTFAFGAPSSTSGSLMP
RYFLQQAGVQPERDFKTVAYSGAHDATVAFVAAGKAQAGVLNASVWDKLVETKKVDPSKVRVFATTPPYFDYNWTVRGDL
DPAVVQKIKAAFLALDPAKPEHKAILELQRASRFIATEPRNYDGIEDAAKTAGLLK

Sequences:

>Translated_296_residues
MTSSTTARRAALRRFAAAAAAVASFSPLLSTQAAEPQVLRVSAIPDEAPTELQRKFKPLGEYLSQATGMKVVFTPVTDYA
AVVESLATRKLDLAWLGGFTYVQARIRTGGTAIPLVQREEDARFTSRFITADPTIQGLADLKGKTFAFGAPSSTSGSLMP
RYFLQQAGVQPERDFKTVAYSGAHDATVAFVAAGKAQAGVLNASVWDKLVETKKVDPSKVRVFATTPPYFDYNWTVRGDL
DPAVVQKIKAAFLALDPAKPEHKAILELQRASRFIATEPRNYDGIEDAAKTAGLLK
>Mature_295_residues
TSSTTARRAALRRFAAAAAAVASFSPLLSTQAAEPQVLRVSAIPDEAPTELQRKFKPLGEYLSQATGMKVVFTPVTDYAA
VVESLATRKLDLAWLGGFTYVQARIRTGGTAIPLVQREEDARFTSRFITADPTIQGLADLKGKTFAFGAPSSTSGSLMPR
YFLQQAGVQPERDFKTVAYSGAHDATVAFVAAGKAQAGVLNASVWDKLVETKKVDPSKVRVFATTPPYFDYNWTVRGDLD
PAVVQKIKAAFLALDPAKPEHKAILELQRASRFIATEPRNYDGIEDAAKTAGLLK

Specific function: Probably forms part of a binding-protein-dependent phosphite transporter. Required for oxidation of phosphite to phosphate [H]

COG id: COG3221

COG function: function code P; ABC-type phosphate/phosphonate transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790543, Length=262, Percent_Identity=28.2442748091603, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168
- InterPro:   IPR005770 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 31973; Mature: 31842

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSTTARRAALRRFAAAAAAVASFSPLLSTQAAEPQVLRVSAIPDEAPTELQRKFKPLG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHH
EYLSQATGMKVVFTPVTDYAAVVESLATRKLDLAWLGGFTYVQARIRTGGTAIPLVQREE
HHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCEEECCEEEEEEEECCCCCEECEEECCC
DARFTSRFITADPTIQGLADLKGKTFAFGAPSSTSGSLMPRYFLQQAGVQPERDFKTVAY
HHHHHHHEEECCCCHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCHHEEE
SGAHDATVAFVAAGKAQAGVLNASVWDKLVETKKVDPSKVRVFATTPPYFDYNWTVRGDL
CCCCCCEEEEEECCCCCCCEECHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEECCC
DPAVVQKIKAAFLALDPAKPEHKAILELQRASRFIATEPRNYDGIEDAAKTAGLLK
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
TSSTTARRAALRRFAAAAAAVASFSPLLSTQAAEPQVLRVSAIPDEAPTELQRKFKPLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHH
EYLSQATGMKVVFTPVTDYAAVVESLATRKLDLAWLGGFTYVQARIRTGGTAIPLVQREE
HHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCEEECCEEEEEEEECCCCCEECEEECCC
DARFTSRFITADPTIQGLADLKGKTFAFGAPSSTSGSLMPRYFLQQAGVQPERDFKTVAY
HHHHHHHEEECCCCHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCHHEEE
SGAHDATVAFVAAGKAQAGVLNASVWDKLVETKKVDPSKVRVFATTPPYFDYNWTVRGDL
CCCCCCEEEEEECCCCCCCEECHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEECCC
DPAVVQKIKAAFLALDPAKPEHKAILELQRASRFIATEPRNYDGIEDAAKTAGLLK
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]