Click here to switch to the map view.

The map label for this gene is cysH [H]

Identifier: 222111121

GI number: 222111121

Start: 2064465

End: 2065106

Strand: Direct

Name: cysH [H]

Synonym: Dtpsy_1929

Alternate gene names: 222111121

Gene position: 2064465-2065106 (Clockwise)

Preceding gene: 222111120

Following gene: 222111122

Centisome position: 54.38

GC content: 68.54

Gene sequence:

>642_bases
ATGAGCACCGCCACGGCAGTCAGCGCCGCCGAACTCGCCCGCGTCAACGCCGAGCACGGCCACGATGCCGCCGCGCTGGT
GGCCTGGGCGCTGGGCCTGGGCCAGACGCCCATCGTCACCACCAATTTCCGCCCGTTCGAGGCCGTGATCCTGCACTTGG
TCACCCGCGTGCAGCCGGGCGTGCCCGTGGTCTGGATGGACAACGGCTACAACACCGAGGCCACCTACCGCTTTGCCGAC
GCGGTGACGAAGCAGCTGGGGCTCAACCTGAAGATCTACCTGCCGCGCCGCTCGCGCGCCCACCGCGAGGCCGTCGAAGG
CCCGACGCCCGCACTGGACGACCCGCGCCACGCCGCGTTCACCGAAGAGGTGAAGCTCGAACCCTTCGCCCGCGCCCTGC
GCGAAACGGCACCCAGGGTGTGGTTCACCGCGCTGCGCGCCACCGACACCGCCGTGCGCGCGCAGATGGAGCCCGTGAGC
ATCAACCCCGACGGCCTGATCAAGGTCGCGCCGCTATTGCACTGGTCGTCCAAACAGTTGCACGAATACTGCCAGCAGCA
CGGCCTGCCCAACAACTTTGACTACGTGGACCCCACCAAGGGCGAAGACAACCGCGAATGCGGCCTGCACCTGGCCCACT
AA

Upstream 100 bases:

>100_bases
GCGTGGACCCGGCCGCGGCCGAACGCCAGTTCGCGCGCTATGCCGCCTTCTACCAGGGCGACGTGCTGGAGCCGCGCCCG
CTGTTCGCCCGGGAGGCCGC

Downstream 100 bases:

>100_bases
AAACGATAGCTGCCTGCGCTTGCCCCACAAGCGCTGGAGCCAGATTTTACTGGAACATCGAATGAACGTCCGTGTTGACT
CCCAAGTGCTCAACCAGCTC

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MSTATAVSAAELARVNAEHGHDAAALVAWALGLGQTPIVTTNFRPFEAVILHLVTRVQPGVPVVWMDNGYNTEATYRFAD
AVTKQLGLNLKIYLPRRSRAHREAVEGPTPALDDPRHAAFTEEVKLEPFARALRETAPRVWFTALRATDTAVRAQMEPVS
INPDGLIKVAPLLHWSSKQLHEYCQQHGLPNNFDYVDPTKGEDNRECGLHLAH

Sequences:

>Translated_213_residues
MSTATAVSAAELARVNAEHGHDAAALVAWALGLGQTPIVTTNFRPFEAVILHLVTRVQPGVPVVWMDNGYNTEATYRFAD
AVTKQLGLNLKIYLPRRSRAHREAVEGPTPALDDPRHAAFTEEVKLEPFARALRETAPRVWFTALRATDTAVRAQMEPVS
INPDGLIKVAPLLHWSSKQLHEYCQQHGLPNNFDYVDPTKGEDNRECGLHLAH
>Mature_212_residues
STATAVSAAELARVNAEHGHDAAALVAWALGLGQTPIVTTNFRPFEAVILHLVTRVQPGVPVVWMDNGYNTEATYRFADA
VTKQLGLNLKIYLPRRSRAHREAVEGPTPALDDPRHAAFTEEVKLEPFARALRETAPRVWFTALRATDTAVRAQMEPVSI
NPDGLIKVAPLLHWSSKQLHEYCQQHGLPNNFDYVDPTKGEDNRECGLHLAH

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=180, Percent_Identity=37.7777777777778, Blast_Score=113, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR011800
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 23587; Mature: 23456

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTATAVSAAELARVNAEHGHDAAALVAWALGLGQTPIVTTNFRPFEAVILHLVTRVQPG
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHCCCC
VPVVWMDNGYNTEATYRFADAVTKQLGLNLKIYLPRRSRAHREAVEGPTPALDDPRHAAF
CCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCCCCCHHH
TEEVKLEPFARALRETAPRVWFTALRATDTAVRAQMEPVSINPDGLIKVAPLLHWSSKQL
HHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEHHHCCCHHHH
HEYCQQHGLPNNFDYVDPTKGEDNRECGLHLAH
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCEECC
>Mature Secondary Structure 
STATAVSAAELARVNAEHGHDAAALVAWALGLGQTPIVTTNFRPFEAVILHLVTRVQPG
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHCCCC
VPVVWMDNGYNTEATYRFADAVTKQLGLNLKIYLPRRSRAHREAVEGPTPALDDPRHAAF
CCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCCCCCHHH
TEEVKLEPFARALRETAPRVWFTALRATDTAVRAQMEPVSINPDGLIKVAPLLHWSSKQL
HHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEHHHCCCHHHH
HEYCQQHGLPNNFDYVDPTKGEDNRECGLHLAH
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1463852 [H]