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The map label for this gene is sir1 [H]

Identifier: 222111119

GI number: 222111119

Start: 2062260

End: 2064047

Strand: Direct

Name: sir1 [H]

Synonym: Dtpsy_1927

Alternate gene names: 222111119

Gene position: 2062260-2064047 (Clockwise)

Preceding gene: 222111118

Following gene: 222111120

Centisome position: 54.32

GC content: 68.4

Gene sequence:

>1788_bases
ATGTACCAGTACACCGAATTCGACCGCCAGTTCGTCCACCTGCGCGCCCAGCAATTCCGCGATCAGCTCGAACGCTGGCA
GCGCGGCGAGTTGACCGACGAGCAACTGCTGCCCCTGCGCCTGCAAAACGGCTGGTACATCCAGCGCTACGCGCCCATGG
CCCGCATCGCCGTGCCCTATGGCGACATCAACAGCGCTCAGCTGCGCATGCTGGCCCACATCGCCCGCGAATACGACCGC
CCTACGCCCGAGCTGCTGGCCCATGCCCAGGCCACGCAGGACCAGCTGCAGGCCGCCCAGCCGGGCCTGACACTGGCCGC
GCCCCCGCTGCGCTACGGCTACGGCCACTTCACCACGCGCACCAACGTGCAGTTCAACTGGATTCCCATCACCCGCGCGG
CCGACGTGATGGACCTGCTGGCCAGCGTGCACATGCACGGCATCCAGACCAGCGGCAACGACATCCGCAACATCACCTGC
GAGGCCTACGCCGGCATCGCCGAGGACGAGATCGTGGACACCCGGCCGTTCGCCGAGATCACGCGCCAGTGGAGTTCGCT
GCACCCCGAGTTCACCTACCTGCCGCGCAAGTTCAAGATCGCCTTCAACGGCGCCGCGGAAGACCGTGCCGCCACCGGCT
GGTATGACATCGGCCTGCAGGCGCTGAAGAACGCGGCTGGCGAGGTGGGCTTTGCCGTCAAGGTGGGCGGCGGCATGGGG
CGCACGCCCGTCATCGGCACCGTGGTGCGTGAATTTCTGCCGTGGGACCAGCTGCTGAACTACATCGAAGCCATCGTGCG
CGTGTACAACAGCTACGGCCGCCGCGACAACAAGTGGAAGGCGCGCATCAAGATCCTGGTCAAGAGCGAAGGCCAGCAGT
TCATCGACGCGGTGGAGGCCGAATACCGCGCCATCCTGGAGCAGGACGGCGCCCCCCACACCATCACCCAGGCCGAGCTG
GACCGCGTGACCGGCCATTTCGTCGTGCCACCACTGCGGCCCGCCGGCCGGCCGCACGGCGTGAACACCTCCGGCCAGCT
GTACCAGCGCTGGCTGCAGCAGAACGTGCGCGGCCACCGCATGGCCGGCCTGAAGGCGGTGACACTGTCGTTCAAGCGCG
TGGGCTTTGCGCCCGGCGATGCCGACGGCGACACGCTGGACGCCCTGGCCCAGCTGGCCGACCAGTTCAGCGCCGGCGAG
GCGCGCCTGACGCACGAGCAGAACCTGCTGCTGCCCTGGGTGCACGAAGCCGACCTGCCCGCGCTGTACGAGGCCGCGCG
CAAGCTGGGCCTGGCGCAGCCCAACATCGGCCTGCTGACGGACATGATCGCCTGCCCGGGCGGCGACTTCTGCTCACTGG
CCAACGCGCGTTCGCTGCCCATCGCCGCGGCGATCACCGAGCGCTACCAGGATTTGGACGAACTGTTCGACATCGGCCCC
ATCGACCTGCACATGAGCGGCTGCATCAACAGCTGCGGCCACCACCACAGCGGCCACATCGGCATCCTGGGCGTGGACAA
GGACGGCAAGGAGTGGTACCAGATCACGCTGGGCGGCTCCGACGGTACGCAGCTGTCCGGCCCCGCCATTGGCGGCAAGG
TGGTCGGCCCGTCGTTCTCGGCCGCCGAAGTGCCCGACGTGATCGAGGCGCTGCTGGACACCTACCGCGCGCTGCGCAAG
GGCAACGAGCTGTTCATCGACACCCTGCGCCGCGTGGGCCAGGACCCGTTCAAGGCCGCCGCCAACGGCGCGCGCCATCC
CAAGGCGGCCGAAGAAGCCGTGGCCTGA

Upstream 100 bases:

>100_bases
GTTTGTCTTTATAAGACAGACTTTTAAAGTGCGCCCATCGATGCTGCGGGCGCCATTCGGGGCCCGGCGGCACCTGTGTT
GAAACGCCCACGGCCCTGCC

Downstream 100 bases:

>100_bases
CCCCATCCGAAAGATCTCGAACACTATGAAAATCATAGCTGCTGGCGCTTTGTCCCTGGGCGCTGACGACCTCAAAACCC
TGCAGATCGCCAACGACGCC

Product: nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MYQYTEFDRQFVHLRAQQFRDQLERWQRGELTDEQLLPLRLQNGWYIQRYAPMARIAVPYGDINSAQLRMLAHIAREYDR
PTPELLAHAQATQDQLQAAQPGLTLAAPPLRYGYGHFTTRTNVQFNWIPITRAADVMDLLASVHMHGIQTSGNDIRNITC
EAYAGIAEDEIVDTRPFAEITRQWSSLHPEFTYLPRKFKIAFNGAAEDRAATGWYDIGLQALKNAAGEVGFAVKVGGGMG
RTPVIGTVVREFLPWDQLLNYIEAIVRVYNSYGRRDNKWKARIKILVKSEGQQFIDAVEAEYRAILEQDGAPHTITQAEL
DRVTGHFVVPPLRPAGRPHGVNTSGQLYQRWLQQNVRGHRMAGLKAVTLSFKRVGFAPGDADGDTLDALAQLADQFSAGE
ARLTHEQNLLLPWVHEADLPALYEAARKLGLAQPNIGLLTDMIACPGGDFCSLANARSLPIAAAITERYQDLDELFDIGP
IDLHMSGCINSCGHHHSGHIGILGVDKDGKEWYQITLGGSDGTQLSGPAIGGKVVGPSFSAAEVPDVIEALLDTYRALRK
GNELFIDTLRRVGQDPFKAAANGARHPKAAEEAVA

Sequences:

>Translated_595_residues
MYQYTEFDRQFVHLRAQQFRDQLERWQRGELTDEQLLPLRLQNGWYIQRYAPMARIAVPYGDINSAQLRMLAHIAREYDR
PTPELLAHAQATQDQLQAAQPGLTLAAPPLRYGYGHFTTRTNVQFNWIPITRAADVMDLLASVHMHGIQTSGNDIRNITC
EAYAGIAEDEIVDTRPFAEITRQWSSLHPEFTYLPRKFKIAFNGAAEDRAATGWYDIGLQALKNAAGEVGFAVKVGGGMG
RTPVIGTVVREFLPWDQLLNYIEAIVRVYNSYGRRDNKWKARIKILVKSEGQQFIDAVEAEYRAILEQDGAPHTITQAEL
DRVTGHFVVPPLRPAGRPHGVNTSGQLYQRWLQQNVRGHRMAGLKAVTLSFKRVGFAPGDADGDTLDALAQLADQFSAGE
ARLTHEQNLLLPWVHEADLPALYEAARKLGLAQPNIGLLTDMIACPGGDFCSLANARSLPIAAAITERYQDLDELFDIGP
IDLHMSGCINSCGHHHSGHIGILGVDKDGKEWYQITLGGSDGTQLSGPAIGGKVVGPSFSAAEVPDVIEALLDTYRALRK
GNELFIDTLRRVGQDPFKAAANGARHPKAAEEAVA
>Mature_595_residues
MYQYTEFDRQFVHLRAQQFRDQLERWQRGELTDEQLLPLRLQNGWYIQRYAPMARIAVPYGDINSAQLRMLAHIAREYDR
PTPELLAHAQATQDQLQAAQPGLTLAAPPLRYGYGHFTTRTNVQFNWIPITRAADVMDLLASVHMHGIQTSGNDIRNITC
EAYAGIAEDEIVDTRPFAEITRQWSSLHPEFTYLPRKFKIAFNGAAEDRAATGWYDIGLQALKNAAGEVGFAVKVGGGMG
RTPVIGTVVREFLPWDQLLNYIEAIVRVYNSYGRRDNKWKARIKILVKSEGQQFIDAVEAEYRAILEQDGAPHTITQAEL
DRVTGHFVVPPLRPAGRPHGVNTSGQLYQRWLQQNVRGHRMAGLKAVTLSFKRVGFAPGDADGDTLDALAQLADQFSAGE
ARLTHEQNLLLPWVHEADLPALYEAARKLGLAQPNIGLLTDMIACPGGDFCSLANARSLPIAAAITERYQDLDELFDIGP
IDLHMSGCINSCGHHHSGHIGILGVDKDGKEWYQITLGGSDGTQLSGPAIGGKVVGPSFSAAEVPDVIEALLDTYRALRK
GNELFIDTLRRVGQDPFKAAANGARHPKAAEEAVA

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

None

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 65812; Mature: 65812

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQYTEFDRQFVHLRAQQFRDQLERWQRGELTDEQLLPLRLQNGWYIQRYAPMARIAVPY
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCEEEEECCCCEEEEECC
GDINSAQLRMLAHIAREYDRPTPELLAHAQATQDQLQAAQPGLTLAAPPLRYGYGHFTTR
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCHHCCCCCEEEE
TNVQFNWIPITRAADVMDLLASVHMHGIQTSGNDIRNITCEAYAGIAEDEIVDTRPFAEI
CCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHEEEHHHHCCCCCCCCCCCCCHHHH
TRQWSSLHPEFTYLPRKFKIAFNGAAEDRAATGWYDIGLQALKNAAGEVGFAVKVGGGMG
HHHHHHCCCCEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCC
RTPVIGTVVREFLPWDQLLNYIEAIVRVYNSYGRRDNKWKARIKILVKSEGQQFIDAVEA
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCHHHHHHHHH
EYRAILEQDGAPHTITQAELDRVTGHFVVPPLRPAGRPHGVNTSGQLYQRWLQQNVRGHR
HHHHHHHCCCCCCCHHHHHHHHCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHH
MAGLKAVTLSFKRVGFAPGDADGDTLDALAQLADQFSAGEARLTHEQNLLLPWVHEADLP
HCCHHHEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCCCCH
ALYEAARKLGLAQPNIGLLTDMIACPGGDFCSLANARSLPIAAAITERYQDLDELFDIGP
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCC
IDLHMSGCINSCGHHHSGHIGILGVDKDGKEWYQITLGGSDGTQLSGPAIGGKVVGPSFS
CEEEHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCEEECCCCC
AAEVPDVIEALLDTYRALRKGNELFIDTLRRVGQDPFKAAANGARHPKAAEEAVA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHCC
>Mature Secondary Structure
MYQYTEFDRQFVHLRAQQFRDQLERWQRGELTDEQLLPLRLQNGWYIQRYAPMARIAVPY
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCEEEEECCCCEEEEECC
GDINSAQLRMLAHIAREYDRPTPELLAHAQATQDQLQAAQPGLTLAAPPLRYGYGHFTTR
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCHHCCCCCEEEE
TNVQFNWIPITRAADVMDLLASVHMHGIQTSGNDIRNITCEAYAGIAEDEIVDTRPFAEI
CCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHEEEHHHHCCCCCCCCCCCCCHHHH
TRQWSSLHPEFTYLPRKFKIAFNGAAEDRAATGWYDIGLQALKNAAGEVGFAVKVGGGMG
HHHHHHCCCCEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCC
RTPVIGTVVREFLPWDQLLNYIEAIVRVYNSYGRRDNKWKARIKILVKSEGQQFIDAVEA
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCHHHHHHHHH
EYRAILEQDGAPHTITQAELDRVTGHFVVPPLRPAGRPHGVNTSGQLYQRWLQQNVRGHR
HHHHHHHCCCCCCCHHHHHHHHCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHH
MAGLKAVTLSFKRVGFAPGDADGDTLDALAQLADQFSAGEARLTHEQNLLLPWVHEADLP
HCCHHHEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCCCCH
ALYEAARKLGLAQPNIGLLTDMIACPGGDFCSLANARSLPIAAAITERYQDLDELFDIGP
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCC
IDLHMSGCINSCGHHHSGHIGILGVDKDGKEWYQITLGGSDGTQLSGPAIGGKVVGPSFS
CEEEHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCEEECCCCC
AAEVPDVIEALLDTYRALRKGNELFIDTLRRVGQDPFKAAANGARHPKAAEEAVA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA